IMUGENE LIMITED — Director's Dealing 2022

Jun 8, 2022

Appendix 3Y Change of Director’s Interest Notice

Rule 3.19A.2

Appendix 3Y

Change of Director’s Interest Notice

Information or documents not available now must be given to ASX as soon as available. Information and documents given to ASX become ASX’s property and may be made public.

Introduced 30/9/2001. Amended 01/01/11

Name of Entity:	Imugene Limited (ASX:IMU)
ABN:	99 009 179 551

We (the entity) give ASX the following information under listing rule 3.19A.2 and as agent for the director for the purposes of section 205G of the Corporations Act.

Name of Director:	Dr Lesley Russell
Date of Last Notice:	11 October 2021

Part 1 - Change of director’s relevant interests in securities

In the case of a trust, this includes interests in the trust made available by the responsible entity of the trust

Note: In the case of a company, interests which come within paragraph (i) of the definition of “notifiable interest of a director” should be disclosed in this part.

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----- Start of picture text ----- Direct or Indirect Interest DirectNature of indirect interest(including registered holder)Note: Provide details of the circumstances giving rise to therelevant interest.Date of change 7 June 2022No. of securities held prior to changeShares OptionsDirect 10,000,000 10,000,000Indirect 500,000 -Total 10,500,000 10,000,000Class Fully Paid Ordinary Shares (IMU) andUnlisted OptionsNumber acquiredShares OptionsDirect 10,000,000 -Indirect - -Total 10,000,000 -Number disposed Shares OptionsDirect - 10,000,000Indirect - -Total - 10,000,000----- End of picture text -----

• See chapter 19 for defined terms.

01/01/2011

Appendix 3Y Page 1

Appendix 3Y Change of Director’s Interest Notice

Value/Consideration	Value/Consideration
	Value/Consideration		$0045	r share
	Note:If consideration is non-cash	rovide details and estimated	. p	.
	,valuation
							---
	No. of securities held a	fter change		SharesOptions
			Direct	20,000,000			-
			Idi	t500000			-
			nrec	,
			Total		20,500,000		-
	Nature of chane		Exercis	of otions
	gExample:on-market trade, off-market trade, exercise of options, issue ofsecurities under dividend reinvestment plan, participation in buy-back

Part 2 – Change of director’s interests in contracts

Note: In the case of a company, interests which come within paragraph (ii) of the definition of “notifiable interest of a director” should be disclosed in this part.

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----- Start of picture text ----- Detail of contract N/ANature of interest N/AName of registered holder N/A(if issued securities)Date of change N/ANo. and class of securities to which N/Ainterest related prior to changeNote: Details are only required for a contract inrelation to which the interest has changedInterest acquired N/AInterest disposed N/AValue/Consideration N/ANote: If consideration is non-cash, provide detailsand an estimated valuationInterest after change N/A----- End of picture text -----

Part 3 – Closed period

art 3 – Closed period
Were the interests in the securities orcontractsdetailedabovetradedduring a +closed period where priorwritten clearance was required?	No
If so, was prior written clearanceprovided to allow the trade to proceedduring this period?	N/A
Ifpriorwrittenclearance wasprovided, on what date was thisprovided?	N/A

The CFO Solution

• See chapter 19 for defined terms.

Appendix 3Y Page 2

01/01/2011