IMUGENE LIMITED — Director's Dealing 2008

Jan 31, 2008

Appendix 3Y Change of Director’s Interest Notice

Rule 3.19A.2

Appendix 3Y

Change of Director’s Interest Notice

Information or documents not available now must be given to ASX as soon as available. Information and documents given to ASX become ASX’s property and may be made public.

Introduced 30/9/2001.

Name of entity: Imugene Limited

ABN: 99 009 179 551

We (the entity) give ASX the following information under listing rule 3.19A.2 and as agent for the director for the purposes of section 205G of the Corporations Act.

Name of Director	Graham Dowland
Date of last notice	9 January 2007

Part 1 - Change of director’s relevant interests in securities

In the case of a trust, this includes interests in the trust made available by the responsible entity of the trust

Note: In the case of a company, interests which come within paragraph (i) of the definition of “notifiable interest of a director” should be disclosed in this part.

Direct or indirect interest	Direct and indirect
Nature of indirect interest (including registered holder) Note: Provide details of the circumstances giving rise to the relevant interest.	Treffina Dowland – (Spouse) Eurasia Pty Ltd – Controlled Body Corporate Avalon Valley Pty Ltd – Controlled Body Corporate
Date of change	31 January 2008
No. of securities held prior to change	Treffina Dowland 4,830,001 Ordinary Shares Eurasia Pty Ltd **Trust> 1,666,667 Ordinary Shares Avalon Valley Pty Ltd **Dowland S/F A/C> 280,000 Ordinary Shares Graham Dowland 13,334 Ordinary Shares 500,000 Performance Options
Class	Various

• See chapter 19 for defined terms.

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Appendix 3Y Change of Director’s Interest Notice

Number acquired	Treffina Dowland 483,001 Ordinary Shares Eurasia Pty Ltd **Trust> 166,667 Ordinary Shares Avalon Valley Pty Ltd **Dowland S/F A/C> 28,000 Ordinary Shares Graham Dowland 1,334 Ordinary Shares Avalon Valley Pty Ltd **Family Trust> 48,572 Ordinary Shares
Number disposed	Nil
Value/Consideration Note: If consideration is non-cash, provide details and estimated valuation	$101,860
No. of securities held after change	Treffina Dowland 5,313,002 Ordinary Shares Eurasia Pty Ltd **Trust> 1,833,334 Ordinary Shares Avalon Valley Pty Ltd **Dowland S/F A/C> 308,000 Ordinary Shares Avalon Valley Pty Ltd **Family Trust> 48,572 Ordinary Shares Graham Dowland 14,668 Ordinary Shares 500,000 Performance Options
Nature of change Example: on-market trade, off-market trade, exercise of options, issue of securities under dividend reinvestment plan, participation in buy-back	Participation in Rights Issue and shortfall placement.

Part 2 – Change of director’s interests in contracts

Note: In the case of a company, interests which come within paragraph (ii) of the definition of “notifiable interest of a director” should be disclosed in this part.

• See chapter 19 for defined terms.

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Appendix 3Y Change of Director’s Interest Notice

Detail of contract	N/A
Nature of interest	N/A
Name of registered holder (if issued securities)	N/A
Date of change	N/A
No. and class of securities to which interest related prior to change Note: Details are only required for a contract in relation to which the interest has changed	N/A
Interest acquired	N/A
Interest disposed	N/A
Value/Consideration Note: If consideration is non-cash, provide details and an estimated valuation	N/A
Interest after change	N/A

• See chapter 19 for defined terms.

Appendix 3Y Page 3

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Appendix 3Y Change of Director’s Interest Notice

Rule 3.19A.2

Appendix 3Y

Change of Director’s Interest Notice

Information or documents not available now must be given to ASX as soon as available. Information and documents given to ASX become ASX’s property and may be made public.

Introduced 30/9/2001.

Name of entity: Imugene Limited

ABN: 99 009 179 551

We (the entity) give ASX the following information under listing rule 3.19A.2 and as agent for the director for the purposes of section 205G of the Corporations Act.

Name of Director	Roger Steinepreis
Date of last notice	22 December 2004

Part 1 - Change of director’s relevant interests in securities

In the case of a trust, this includes interests in the trust made available by the responsible entity of the trust

Note: In the case of a company, interests which come within paragraph (i) of the definition of “notifiable interest of a director” should be disclosed in this part.

Direct or indirect interest	Indirect
Nature of indirect interest (including registered holder) Note: Provide details of the circumstances giving rise to the relevant interest.	Blueknight Corporation Pty Ltd – Controlled Body Corporate
Date of change	31 January 2008
No. of securities held prior to change	4,263,678 Ordinary Shares
Class	Ordinary Shares
Number acquired	726,368 Ordinary Shares
Number disposed	Nil
Value/Consideration Note: If consideration is non-cash, provide details and estimated valuation	$101,692
No. of securities held after change	4,990,046 Ordinary Shares

• See chapter 19 for defined terms.

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Appendix 3Y Change of Director’s Interest Notice

Nature of change Participation in Rights Issue and shortfall Example: on-market trade, off-market trade, exercise of options, issue of placement securities under dividend reinvestment plan, participation in buy-back

Part 2 – Change of director’s interests in contracts

Note: In the case of a company, interests which come within paragraph (ii) of the definition of “notifiable interest of a director” should be disclosed in this part.

Detail of contract	N/A
Nature of interest	N/A
Name of registered holder (if issued securities)	N/A
Date of change	N/A
No. and class of securities to which interest related prior to change Note: Details are only required for a contract in relation to which the interest has changed	N/A
Interest acquired	N/A
Interest disposed	N/A
Value/Consideration Note: If consideration is non-cash, provide details and an estimated valuation	N/A
Interest after change	N/A

• See chapter 19 for defined terms.

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Appendix 3Y Change of Director’s Interest Notice

Rule 3.19A.2

Appendix 3Y

Change of Director’s Interest Notice

Information or documents not available now must be given to ASX as soon as available. Information and documents given to ASX become ASX’s property and may be made public.

Introduced 30/9/2001.

Name of entity: Imugene Limited

ABN: 99 009 179 551

We (the entity) give ASX the following information under listing rule 3.19A.2 and as agent for the director for the purposes of section 205G of the Corporations Act.

Name of Director	Warwick Lamb
Date of last notice	9 January 2007

Part 1 - Change of director’s relevant interests in securities

In the case of a trust, this includes interests in the trust made available by the responsible entity of the trust

Note: In the case of a company, interests which come within paragraph (i) of the definition of “notifiable interest of a director” should be disclosed in this part.

Direct or indirect interest	Direct and indirect
Nature of indirect interest (including registered holder) Note: Provide details of the circumstances giving rise to the relevant interest.	Vetspec Pty Ltd - Controlled Body Corporate)
Date of change	1 January 2007
No. of securities held prior to change	Held directly 6,150,001 Ordinary Shares 2,500,000 Performance Options Vetspec Pty Ltd 250,000 Ordinary Shares
Class	Various
Number acquired	Held directly 1,095,001 Ordinary Shares Vetspec Pty Ltd 25,000 Ordinary Shares
Number disposed	Nil

• See chapter 19 for defined terms.

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Appendix 3Y Change of Director’s Interest Notice

Value/Consideration Note: If consideration is non-cash, provide details and estimated valuation	$156,800
No. of securities held after change	Held directly 7,245,002 Ordinary Shares 2,500,000 Performance Options Vetspec Pty Ltd 275,000 Ordinary Shares
Nature of change Example: on-market trade, off-market trade, exercise of options, issue of securities under dividend reinvestment plan, participation in buy-back	Participation in Rights Issue and shortfall placement.

Part 2 – Change of director’s interests in contracts

Note: In the case of a company, interests which come within paragraph (ii) of the definition of “notifiable interest of a director” should be disclosed in this part.

Detail of contract	N/A
Nature of interest	N/A
Name of registered holder (if issued securities)	N/A
Date of change	N/A
No. and class of securities to which interest related prior to change Note: Details are only required for a contract in relation to which the interest has changed	N/A
Interest acquired	N/A
Interest disposed	N/A
Value/Consideration Note: If consideration is non-cash, provide details and an estimated valuation	N/A
Interest after change	N/A

• See chapter 19 for defined terms.

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