IMUGENE LIMITED — Director's Dealing 2004

Dec 21, 2004

Rule 3.19A.2

Appendix 3Y Change of Director's Interest Notice

Information or documents not available now must be given to ASX as soon as available. Information and documents given to ASX become ASX's property and may be made public.

Introduced 30/9/2001.

Name of entity	IMUGENE LIMITED
IABN	99 009 179 551

We (the entity) give ASX the following information under listing rule 3.19A.2 and as agent for the director for the purposes of section 205G of the Corporations Act.

Name of Director	GRAHAM DOWLAND
l Date of last notice.	1 December 2003

Part 1 - Change of director's relevant interests in securities

In the case of a trust, this includes interests in the trust made available by the responsible entity of the trust

Note: In the case of a company, interests which come within paragraph (i) of the definition of "notifiable interest of a director"
should be disclosed in this part.

Direct or indirect interest	Direct and Indirect
Nature of indirect interest (including registered holder) Note: Provide details of the circumstances giving rise to the relevant interest.	• Eurasia Pty Ltd, G Dowland Shareholder and Director. Treffina Dowland, Spouse.
Date of change	22 December 2004
No. of securities held prior to change	13,334 Ordinary Shares held by ٠ Graham Dowland 1,666,667 Ordinary Shares held by ۰ Eurasia Pty Ltd 5,086,667 Ordinary Shares held by Treffina Dowland 23,334 Options held by Treffina $\bullet$ Dowland 2,500,000 Performance Options held $\bullet$ by Graham Dowland
Class	Fully paid ordinary shares ٠ Options exercisable at 11.25 cents on or before 31 December 2004 Performance Options exercisable at $\bullet$ various prices
Number acquired	23,334 Ordinary Shares
Number disposed	23,334 Options

⁺ See chapter 19 for defined terms.

Value/Consideration Note: If consideration is non-cash, provide details and estimated valuation	11.25 cents each
No. of securities held after change	13,334 Ordinary Shares held b٧ Graham Dowland 1,666,667 Ordinary Shares held by Eurasia Pty Ltd 5,110,001 Ordinary Shares held by Treffina Dowland • 2,500,000 Performance Options held by Graham Dowland
Nature of change Example: on-market trade, off-market trade, exercise of options, issue of securities under dividend reinvestment plan, participation in buy-back	Exercise of 23,334 Options at 11.25 cents each

Part 2 - Change of director's interests in contracts

Note: In the case of a company, interests which come within paragraph (ii) of the definition of "notifiable interest of a director"
should be disclosed in this part.

Detail of contract	Not Applicable
Nature of interest
Name of registered holder (if issued securities)
Date of change
No. and class of securities to which interest related prior to change Note: Details are only required for a contract in relation to which the interest has changed
Interest acquired
Interest disposed
Value/Consideration Note: if consideration is non-cash, provide details and an estimated valuation
Interest after change

⁺ See chapter 19 for defined terms.

Rule 3.19A.2

Appendix 3Y Change of Director's Interest Notice

Information or documents not available now must be given to ASX as soon as available. Information and documents given to ASX become ASX's property and may be made public.

Introduced 30/9/2001.

Name of entity	IMUGENE LIMITED
IABN	99 009 179 551

We (the entity) give ASX the following information under listing rule 3.19A.2 and as agent for the director for the purposes of section 205G of the Corporations Act.

Name of Director	ROGER STEINEPREIS
l Date of last notice.	1 August 2003

Part 1 - Change of director's relevant interests in securities

In the case of a trust, this includes interests in the trust made available by the responsible entity of the trust

Note: In the case of a company, interests which come within paragraph (i) of the definition of "notifiable interest of a director"
should be disclosed in this part.

Direct or indirect interest	Indirect
Nature of indirect interest (including registered holder) Note: Provide details of the circumstances giving rise to the relevant interest	Blueknight Corporation Pty Ltd, director and beneficial shareholder
Date of change	22 December 2004
No. of securities held prior to change	3,202,937 fully paid ordinary shares ۰ held by Blueknight Corporation Pty Ltd. 1,060,741 unlisted options held by Blueknight Corporation Pty Ltd.
Class	Fully paid ordinary shares Options exercisable at 11.25 cents on or before 31 December 2004
Number acquired	1,060,741 Ordinary Shares
Number disposed	1,060,741 Options
Value/Consideration Note: If consideration is non-cash, provide details and estimated valuation	11.25 cents each
No. of securities held after change	4,263,678 fully paid ordinary shares $\bullet$ held by Blueknight Corporation Pty Ltd

⁺ See chapter 19 for defined terms.

Nature of change Example: on-market trade, off-market trade, exercise of options, issue of securities under dividend reinvestment plan, participation in buy-back	Exercise of 1,060,741 Options at 11.25 cents each

Part 2 - Change of director's interests in contracts

Note: In the case of a company, interests which come within paragraph (ii) of the definition of "notifiable interest of a director"
should be disclosed in this part.

Detail of contract	Not Applicable
Nature of interest
Name of registered holder (if issued securities)
Date of change
No. and class of securities to which interest related prior to change Note: Details are only required for a contract in relation to which the interest has changed
Interest acquired
Interest disposed
Value/Consideration Note: if consideration is non-cash, provide details and an estimated valuation.
Interest after change

⁺ See chapter 19 for defined terms.

Appendix 3Y

Rule 3,19A.2

Change of Director's Interest Notice

Information or documents not available now must be given to ASX as soon as available. Information and documents given to ASX become ASX's property and may be made public.

Introduced 30/9/2001.

Name of entity	IMUGENE LIMITED
IABN	99 009 179 551

We (the entity) give ASX the following information under listing rule 3.19A.2 and as agent for the director for the purposes of section 205G of the Corporations Act.

Name of Director	WARWICK LAMB
l Date of last notice.	1 December 2003

Part 1 - Change of director's relevant interests in securities

In the case of a trust, this includes interests in the trust made available by the responsible entity of the trust

Note: In the case of a company, interests which come within paragraph (i) of the definition of "notifiable interest of a director" should be disclosed in this part.

Direct or indirect interest	Direct
Nature of indirect interest (including registered holder) Note: Provide details of the circumstances giving rise to the relevant interest.	Not Applicable
Date of change	22 December 2004
No. of securities held prior to change	6,133,334 Ordinary Shares ۰ 46,667 Options ۰ 2,500,000 Performance Options
Class	Fully paid ordinary shares ۰ Options exercisable at 11.25 cents on ۰ or before 31 December 2004 Performance Options exercisable at $\bullet$ various prices
Number acquired	46,667 Ordinary Shares
Number disposed	46,667 Options
Value/Consideration Note: If consideration is non-cash, provide details and estimated valuation	11.25 cents each
No. of securities held after change	6,180,001 Ordinary Shares ۰ 2,500,000 Performance Options

⁺ See chapter 19 for defined terms.

Nature of change Example: on-market trade, off-market trade, exercise of options, issue of securities under dividend reinvestment plan, participation in buv-back	Exercise of 46,667 Options at 11.25 cents each

Part 2 - Change of director's interests in contracts

Note: In the case of a company, interests which come within paragraph (ii) of the definition of "notifiable interest of a director"
should be disclosed in this part.

Detail of contract	Not Applicable
Nature of interest
Name of registered holder
(if issued securities)
Date of change
No. and class of securities to
which interest related prior to
change Note: Details are only required for a contract in relation to which the interest has changed
Interest acquired
Interest disposed
Value/Consideration Note: if consideration is non-cash, provide details and an estimated valuation
Interest after change

⁺ See chapter 19 for defined terms.