IMPEDIMED LIMITED — Director's Dealing 2007

Oct 24, 2007

Appendix 3X Initial Director’s Interest Notice

Rule 3.19A.1

Appendix 3X

Initial Director’s Interest Notice

Information or documents not available now must be given to ASX as soon as available. Information and documents given to ASX become ASX’s property and may be made public.

Introduced 30/9/2001.

Name of entity	IMPEDIMED LIMITED
ABN	65 089 705 144

We (the entity) give ASX the following information under listing rule 3.19A.1 and as agent for the director for the purposes of section 205G of the Corporations Act.

Name of Director	Dr Michael Panaccio
Date of appointment	25 January 2007

Part 1 - Director’s relevant interests in securities of which the director is the registered holder

In the case of a trust, this includes interests in the trust made available by the responsible entity of the trust

Note: In the case of a company, interests which come within paragraph (i) of the definition of “notifiable interest of a director” should be disclosed in this part.

Number & class of securities

Nil

• See chapter for defined terms.

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Appendix 3X Initial Director’s Interest Notice

Part 2 – Director’s relevant interests in securities of which the director is not the registered holder

In the case of a trust, this includes interests in the trust made available by the responsible entity of the trust

Name of holder & nature of interest Note: Provide details of the circumstances giving rise to the relevant interest. Masto Pty Ltd (a company controlled by Michael Panaccio) Starfish Technology Fund 1, LP (an entity controlled by Michael Panaccio) Various holders (deemed relevant interest under section 608(3)(b) of the Corporations Act in shares which are subject to voluntary and mandatory escrow agreements with the entity–refer Annexure A)

Number & class of Securities 229,000 ordinary shares • Subscribed for at IPO, not subject to escrow 114,500 options to subscribe for ordinary shares at an exercise price of $0.72 per share • subscribed for at IPO, not subject to escrow 24,285,465 ordinary shares • 6,395,783 subject to voluntary escrow for 12 months • 17,889,682 not subject to escrow (including 5,526,400 subscribed for at IPO) 2,763,200 options to subscribe for ordinary shares at an exercise price of $0.72 per share • Subscribed for at IPO, not subject to escrow 28,819,833 ordinary shares

Part 3 – Director’s interests in contracts

Note: In the case of a company, interests which come within paragraph (ii) of the definition of “notifiable interest of a director” should be disclosed in this part.

Detail of contract	Nil
Nature of interest
Name of registered holder (if issued securities)
No. and class of securities to which interest relates

• See chapter for defined terms.

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Appendix 3X Initial Director’s Interest Notice

Annexure

Name of entity	IMPEDIMED LIMITED
ABN	65 089 705 144

Part 2 – Director’s relevant interests in securities of which the director is not the registered holder

In the case of a trust, this includes interests in the trust made available by the responsible entity of the trust

Name of holder & nature of interest Note: Provide details of the circumstances giving rise to the relevant interest. Candlegrove Pty Ltd Cherrell Hirst Colin Frederick & Lynette Anne Brown Greg Brown Klemzig Pty Ltd Melvyn Bridges Parma Corporation Pty Ltd Alan Armstrong Biophys Pty Ltd ACN 111 517 956 Dennis Bourque Bruce Cairney Steve Conway Chelsea Services, Inc. Mike Drotar Intellidesign Pty Ltd ACN 068 564 036 Matt Leitner Pamela Cove Pty Ltd ACN 074 544 906 Queensland University of Technology Roxanne Pty Ltd ACN 110 755 345 Carl Sanchez Dennis Schlaht Steve Smith Steve St. Amand Statewide Superannuation Pty Ltd ACN 008 099 223	Number & class of Securities 16,331 ordinary shares 69,826 ordinary shares 6,364 ordinary shares 4,335,349 ordinary shares 86,791 ordinary shares 69,826 ordinary shares 4,235,000 ordinary shares 18,850 ordinary shares 1,260,870 ordinary shares 564,061 ordinary shares 195,432 ordinary shares 325,773 ordinary shares 42,212 ordinary shares 154,347 ordinary shares 658,375 ordinary shares 2,256 ordinary shares 30,928 ordinary shares 373,815 ordinary shares 1,260,870 ordinary shares 42,212 ordinary shares 121,964 ordinary shares 538,927 ordinary shares 35,284 ordinary shares 916,546 ordinary shares

• See chapter for defined terms.

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Appendix 3X Initial Director’s Interest Notice

Thorpe Road Nominees Pty Ltd	4,134,373 ordinary shares
ACN 007 852 173
Tregoning Trailers Distributors Pty Ltd	2,064,005 ordinary shares
ACN 007 565 175
Ian Tregoning	20,619 ordinary shares
UniQuest Pty Limited ACN 010 529 898	1,490,000 ordinary shares
Versant Side Fund III LP	28,346 ordinary shares
Versant Venture Capital III LP	4,803,735 ordinary shares
Westscheme Pty Ltd ACN 009 194 218	916,546 ordinary shares

• See chapter for defined terms.

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