Immunome Inc. — Director's Dealing 2025

Dec 22, 2025

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: Immunome Inc. (IMNM)
CIK: 0001472012
Period of Report: 2025-12-19

Reporting Person: Higgins Jack (N/A)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2025-12-19	Common Stock	G	1000	—	Disposed	39729	Direct
2025-12-19	Common Stock	G	1000	—	Acquired	1000	Indirect
2025-12-19	Common Stock	G	1000	—	Disposed	38729	Direct
2025-12-19	Common Stock	G	1000	—	Acquired	1000	Indirect
2025-12-19	Common Stock	G	1000	—	Disposed	37729	Direct
2025-12-19	Common Stock	G	1000	—	Acquired	1000	Indirect

Footnotes

F1: Reflects the gift of shares by the Reporting Person to a custodial account for the child of the Reporting Person established pursuant to the Uniform Transfer to Minors Act, for which the Reporting Person serves as a custodian. The Reporting Person disclaims beneficial ownership of these shares, and this report shall not be deemed an admission that the Reporting Person is the beneficial owner of such shares for purposes of Section 16 or for any other purpose.

F2: The shares are subject to a lockup agreement entered into by the Reporting Person on December 15, 2025 (the "Lock-up Agreement"). The transferee has agreed to be bound by the terms of the Lock-up Agreement.