ILLUMINA, INC. — Director's Dealing 2011

Jan 31, 2011

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: ILLUMINA INC (ILMN)
CIK: 0001110803
Period of Report: 2011-01-27

Reporting Person: FLATLEY JAY T (Director, President & CEO)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2011-01-27	Common Stock	M	21743	$4.3	Acquired	347647	Direct
2011-01-27	Common Stock	S	21743	$70.495	Disposed	325904	Direct
2011-01-27	Common Stock	M	3257	$4.3	Acquired	329161	Direct
2011-01-27	Common Stock	S	3257	$71.066	Disposed	325904	Direct
2011-01-28	Common Stock	F	1750	$69.05	Disposed	324154	Direct
2011-01-31	Common Stock	F	2800	$69.34	Disposed	321354	Direct

Derivative Transactions

Date	Security	Exercise Price	Code	Shares	A/D	Expiration	Underlying	Ownership
2011-01-27	Non-Qualified Stock Option (right to buy)	$4.3	M	25000	Disposed	2015-02-25	Common Stock (25000)	Direct

Holdings (Non-Derivative)

Security	Shares	Ownership
Common Stock	15000	Indirect

Footnotes

F1: The sale was made pursuant to a 10b5-1 plan.

F2: Weighted average sale price representing 21,743 shares sold ranging from $69.95 to $70.90 per share. Number of shares sold at each separate price will be made available to the SEC staff, the issuer, or a security holder of the issuer upon request.

F3: Weighted average sale price representing 3,257 shares sold ranging from $70.985 to $71.24 per share. Number of shares sold at each separate price will be made available to the SEC staff, the issuer, or a security holder of the issuer upon request.