ILLUMINA, INC. — Director's Dealing 2011

Jan 13, 2011

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: ILLUMINA INC (ILMN)
CIK: 0001110803
Period of Report: 2011-01-11

Reporting Person: HENRY CHRISTIAN O (Sr VP & CFO)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2011-01-11	Common Stock	M	4582	$10.485	Acquired	30654	Direct
2011-01-11	Common Stock	S	4582	$66.8358	Disposed	26072	Direct
2011-01-11	Common Stock	M	418	$10.485	Acquired	26490	Direct
2011-01-11	Common Stock	S	418	$67.2652	Disposed	26072	Direct
2011-01-11	Common Stock	M	6844	$20.04	Acquired	32916	Direct
2011-01-11	Common Stock	S	6844	$66.8409	Disposed	26072	Direct
2011-01-11	Common Stock	M	656	$20.04	Acquired	26728	Direct
2011-01-11	Common Stock	S	656	$67.2556	Disposed	26072	Direct
2011-01-11	Common Stock	M	4570	$32.485	Acquired	30642	Direct
2011-01-11	Common Stock	S	4570	$66.8227	Disposed	26072	Direct
2011-01-11	Common Stock	M	430	$32.485	Acquired	26502	Direct
2011-01-11	Common Stock	S	430	$67.2553	Disposed	26072	Direct

Derivative Transactions

Date	Security	Exercise Price	Code	Shares	A/D	Expiration	Underlying	Ownership
2011-01-11	Non-Qualified Stock Option (right to buy)	$10.485	M	5000	Disposed	2016-01-30	Common Stock (5000)	Direct
2011-01-11	Non-Qualified Stock Option (right to buy)	$20.04	M	7500	Disposed	2017-01-25	Common Stock (7500)	Direct
2011-01-11	Non-Qualified Stock Option (right to buy)	$32.485	M	5000	Disposed	2018-01-29	Common Stock (5000)	Direct

Footnotes

F1: The sale was made pursuant to a 10b5-1 plan.

F2: Weighted average sale price representing 4,582 shares sold ranging from $66.17 to $67.15 per share. Number of shares sold at each separate price will be made available to the SEC staff, the issuer, or a security holder of the issuer upon request.

F3: Weighted average sale price representing 418 shares sold ranging from $67.19 to $67.29 per share. Number of shares sold at each separate price will be made available to the SEC staff, the issuer, or a security holder of the issuer upon request.

F4: Weighted average sale price representing 6,844 shares sold ranging from $66.175 to $67.14 per share. Number of shares sold at each separate price will be made available to the SEC staff, the issuer, or a security holder of the issuer upon request.

F5: Weighted average sale price representing 656 shares sold ranging from $67.21 to $67.28 per share. Number of shares sold at each separate price will be made available to the SEC staff, the issuer, or a security holder of the issuer upon request.

F6: Weighted average sale price representing 4,570 shares sold ranging from $66.17 to $67.16 per share. Number of shares sold at each separate price will be made available to the SEC staff, the issuer, or a security holder of the issuer upon request.

F7: Weighted average sale price representing 430 shares sold ranging from $67.21 to $67.30 per share. Number of shares sold at each separate price will be made available to the SEC staff, the issuer, or a security holder of the issuer upon request.