ILLUMINA, INC. — Director's Dealing 2010

Jan 15, 2010

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: ILLUMINA INC (ILMN)
CIK: 0001110803
Period of Report: 2010-01-13

Reporting Person: Cabou Christian (Sr VP & General Counsel)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2010-01-13	Common Stock	M	4000	$28.45	Acquired	21499	Direct
2010-01-13	Common Stock	S	4000	$40	Disposed	17499	Direct
2010-01-13	Common Stock	M	6800	$20.04	Acquired	24299	Direct
2010-01-13	Common Stock	S	6800	$39.805	Disposed	17499	Direct
2010-01-13	Common Stock	M	3200	$20.04	Acquired	20699	Direct
2010-01-13	Common Stock	S	3200	$40.357	Disposed	17499	Direct

Derivative Transactions

Date	Security	Exercise Price	Code	Shares	A/D	Expiration	Underlying	Ownership
2010-01-13	Non-Qualified Stock Option (right to buy)	$20.04	M	10000	Disposed	2017-01-25	Common Stock (10000)	Direct
2010-01-13	Non-Qualified Stock Option (right to buy)	$28.45	M	4000	Disposed	2019-01-28	Common Stock (4000)	Direct

Holdings (Non-Derivative)

Security	Shares	Ownership
Common Stock	1000	Indirect

Footnotes

F1: The sale was made pursuant to a 10b5-1 plan.

F2: Weighted average sale price representing 6,800 shares sold ranging from $39.23 to $40.19 per share. Number of shares sold at each separate price will be made available to the SEC staff, the issuer, or a security holder of the issuer upon request.

F3: Weighted average sale price representing 3,200 shares sold ranging from $40.24 to $40.68 per share. Number of shares sold at each separate price will be made available to the SEC staff, the issuer, or a security holder of the issuer upon request.