HLS Therapeutics Inc. — AGM Information 2021

May 28, 2021

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NOTICE OF ANNUAL MEETING OF SHAREHOLDERS

NOTICE IS HEREBY GIVEN that the annual meeting (the “ Meeting ”) of the holders (“ Shareholders ”) of common shares (“ Common Shares ”) of HLS Therapeutics Inc. (the “ Company ”) is scheduled to be held on Friday June 18, 2021 at 10:00 a.m. (Toronto time) in a virtual format via live webcast available online using https://virtualmeetings.tsxtrust.com/1154 for the following purposes:

• (a) to receive the audited consolidated financial statements of the Company as at and for the year ended December 31, 2020 together with the auditor’s report thereon;

• (b) to elect directors of the Company for the ensuing year;

• (c) to reappoint the auditor of the Company for the ensuing year and authorize the directors of the Company to fix such auditor’s remuneration;

• (d) to consider and, if deemed advisable, to pass, with or without variation, an ordinary resolution approving certain amendments to the Company’s stock option plan, as more particularly described in the accompanying management information circular (the “ Circular ”), and approving the unallocated options thereunder; and

• (e) to transact such other business as may properly be brought before the Meeting or any adjournment(s) thereof.

The accompanying Circular provides additional information relating to the matters to be dealt with at the Meeting. The directors of the Company have fixed May 14, 2021 as the record date for determining those Shareholders entitled to receive notice of and vote at the Meeting.

The Company has been carefully monitoring the outbreak of COVID-19. To address the ongoing public health impact of COVID-19 and mitigate risks to the health and safety of the Company’s communities, shareholders, employees and other stakeholders, the Company will be conducting the Meeting in a virtual only format via live audio webcast available online using https://virtual-meetings.tsxtrust.com/1154. Registered Shareholders and duly appointed proxyholders will be able to attend, submit questions and vote at the virtual Meeting. The Company hopes that hosting a virtual meeting helps enable greater participation by Shareholders by allowing Shareholders that might not otherwise be able to travel to a physical meeting to attend online, while minimizing the health risks that are associated with large gatherings.

A registered Shareholder may attend the Meeting virtually or may be represented by proxy. If you are a registered Shareholder (i.e., you hold a physical certificate representing your Common Shares in your name), whether or not you plan to attend the Meeting, we encourage you to exercise your right to vote by dating, signing and returning the accompanying form of proxy to TSX Trust Company. To be valid, completed proxy forms must be dated, completed, signed and deposited with TSX Trust Company (i) by mail using the enclosed return envelope or one addressed to TSX Trust Company, 301 - 100 Adelaide Street West, Toronto, ON, M5H 4H1, Canada (Attention: Proxy Department), (ii) by hand delivery to TSX Trust Company, 301 – 100 Adelaide Street West, Toronto, ON, M5H 4H1, Canada, (iii) by facsimile at (416) 595-9593, or (iv) through the internet at www.voteproxyonline.com, in each case no later than 10:00 a.m. (Toronto time) on June 16, 2021 or, if the Meeting is adjourned or postponed, not less than 48 hours (excluding Saturdays, Sundays and statutory holidays in Toronto, Ontario) before any adjournment or postponement of the Meeting.

A non-registered Shareholder may attend the Meeting and vote virtually by duly appointing themselves as proxyholder or may attend the Meeting (but may not vote) as a guest. If you are a non-registered Shareholder and have received these materials from your broker or another intermediary, please complete and return the voting instruction form or other authorization form provided to you by your broker or intermediary in accordance with the instructions provided. Failure to do so may result in your Common Shares not being eligible to be voted at the Meeting.

Dated at Toronto, Ontario, this 18th day of May, 2021.

BY ORDER OF THE BOARD OF DIRECTORS OF HLS THERAPEUTICS INC.

“Ryan C. Lennox”

RYAN C. LENNOX Corporate Secretary and Senior Vice President, Legal, HR and Compliance

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