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GENINCODE PLC Earnings Release 2025

Jun 8, 2026

7669_10-k_2026-06-08_1ec53bf1-3105-4b23-a314-2e1226333d3d.html

Earnings Release

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National Storage Mechanism | Additional information

RNS Number : 2754H

GENinCode PLC

08 June 2026

8 June 2026

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GENinCode Plc

("GENinCode" or the "Company")

Final results

Well positioned for accelerated commercial scale up with revenue growth and expanding US adoption

Oxford, UK. GENinCode Plc (AIM: GENI), the predictive genetics company focused on the prevention of cardiovascular disease ("CVD") and risk of ovarian cancer announces its audited final results for the year ended 31 December 2025 ("FY25"). FY25 saw the Company strengthen its revenues in the US and Europe.   

Operational highlights

· Revenues increased by 14% year on year to £3.1m, (2024: £2.7m) driven by volume growth in US and EU.

· FDA - CARDIO inCode-Score: FDA 'De Novo' Supervisory Review completed. Discussions with FDA were extended to ensure agreement of the current ongoing program to resolve the outstanding deficiencies. Submission of New De Novo PMA expected during Q3 2026.

· Thermo Fisher - Collaboration agreement to manufacture, distribute and sell CARDIO inCode - Coronary Artery Disease Polygenic Risk Score (CAD PRS) test through the Thermo Fisher lab network in US and EMEA.
· US Sales - Increasing commercial sales of LIPID inCode and CARDIO inCode® with over 45 clinics and hospital Institutions onboarded at the end of 2025.
· New York State Department of Health - Clinical approval received for CARDIO inCode (CAD PRS).
· Reimbursement - Inclusion of CARDIO inCode in 2025 US clinical lab fee schedule.
· Growth of LIPID inCode:

NHS expansion in North of England recently offset by headwinds from major strategic, organisational and funding changes across the NHS.
University Clinic Dresden, Germany growth in primary care diagnosis and expansion of LIPID inCode and THROMBO inCode in Spain and Italy.
· Spanish regions - CARDIO inCode pilot progressing in Extremadura and Catalonia regions of Spain.
· ROCA - First ROCA commercial contract with NHS (UCLH) announced with ongoing contractual discussions with other NHS trusts.

· Despite margins improving to 59% (2024: 53%), adjusted EBITDA loss widened to £4.9m (2024: loss of (£4.4m)) reflecting increased commercial support and a reduced 2025 annual R&D tax credit.

· Cash reserves of £0.8m at 31 December 2025 (2024: £1.1m)

Post-period end

· Successful completion of a £4.7m secondary placing to support scale up and commercialisation.

· American College of Cardiology and American Heart Association (ACC/AHA) Dyslipidemia and Lipid Management guidelines updated including CAD PRS new 'risk enhancer' for prevention of heart disease.  

· Progressing manufacturing and commercial preparations for CARDIO inCode (CAD PRS) launch with Thermo Fisher.  

Current trading and Outlook

·    First four months of the year to April 2026 consolidated revenues are broadly in line with the same period in 2025, despite lower revenues from NHS and Catalonia pilot study.

·    Over 70 US Institutions and clinics now onboarded with ramp up in orders over the first four months of 2026 supported by new US ACC/AHA guidelines including CAD PRS for prevention of heart disease.

·    Ongoing commercial discussions with Thermo Fisher regarding pricing and distribution of CARDIO inCode.

·    Ongoing strategic discussions with NHS for prevention of heart disease and surveillance of ovarian cancer.

·    During 2026, the Company expects to complete the following key deliverables:

o  Increase in year-on-year revenues, improved margins with a reduction in EBITDA losses moving the Company towards breakeven

o  Commercial expansion of LIPID inCode® and scale-up of CARDIO inCode® with Thermo Fisher

o  Submit new FDA De Novo PMA for CARDIO inCode, targeting an approval end Q4.26.

o  Expansion of the MVZ Uniklinikum, Germany collaborative programme to provide LIPID inCode® testing for patients

o  Build on EU partnerships and finalise ongoing collaborative discussions

o  Growth of ROCA® trust adoption across the NHS and expansion in EU

o  Continued strengthening of the commercial, marketing and selling teams to support revenue growth

Matthew Walls, Chief Executive Officer of GENinCode Plc said: "We continue to strengthen our commercial position supported by the progress of our Thermo Fisher collaboration in the US and EU and the recent US ACC/AHA guideline changes which have increased visibility of our testing and established Polygenic Risk Scores as a new 'risk enhancer' for the prevention of heart disease. Discussions have progressed with the FDA and we anticipate filing our updated De Novo PMA submission in Q3.2026. We have a busy period ahead and anticipate continued growth and commercial updates which we will advise in due course. With a strengthened balance sheet following our £4.7 million fundraise, growing commercial traction and continued progress towards our FDA submission, we believe we are well positioned to accelerate growth and deliver on our strategic objectives."

Analyst briefing

A briefing open to equity research analysts will take place on Monday, 8 June 2026 at 09.30am BST. To register and for more details please contact Walbrook PR on [email protected].

Investor presentation

Matthew Walls, Chief Executive Officer, and Paul Foulger, Chief Financial Officer, will provide a live presentation relating to the results via the Investor Meet Company platform on Wednesday, 10 June at 11am BST.

The presentation is open to all existing and potential shareholders. Questions can be submitted pre-event via the Investor Meet Company dashboard until 9am the day before the meeting or at any time during the live presentation.

Investors can sign up to Investor Meet Company for free and add to meet GENinCode here. Investors who already follow GENinCode on the Investor Meet Company platform will automatically be invited.

For more information visit www.genincode.com

Enquiries:

GENinCode Plc www.genincode.com or via Walbrook PR
Matthew Walls, CEO
Cavendish Capital Markets Limited Tel: +44 (0)20 7397 8900
Giles Balleny / Trisyia Jamaludin  (Corporate Finance)
Nigel Birks (Life Sciences Specialist Sales)

Harriet Ward (Corporate Broking)
Dale Bellis / Michael Johnson (Sales)
Walbrook PR Limited
Anna Dunphy Tel: 020 7933 8780 or [email protected]

About GENinCode:

GENinCode Plc is a UK based company specialising in genetic risk assessment of cardiovascular disease. Cardiovascular disease is the leading cause of death and disability worldwide.

GENinCode operates business units in the UK, Europe through GENinCode S.L.U, and in the United States through GENinCode U.S. Inc.

GENinCode predictive technology provides patients and physicians with globally leading preventative care and treatment strategies. GENinCode CE marked invitro-diagnostic molecular tests combine clinical algorithms and bioinformatics to provide advanced patient risk assessment to predict cardiovascular disease.

CHAIRMAN AND CHIEF EXECUTIVE OFFICER'S STATEMENT

On behalf of the Board, we are pleased to present the audited financial statements for the twelve-month period ended 31 December 2025 for GENinCode Plc. 

This statement provides a summary of progress over the past year for the Group, recent developments, and an outlook for the year ahead.    

2025 Business review

During the period, the Company saw a 14% increase in revenues to £3.1m (2023: £2.7m), driven by growth across its European and US businesses.

GENinCode is a genetics company focused on the prevention of cardiovascular disease ("CVD") and the early detection of ovarian cancer. The Group's test portfolio includes:

CARDIO inCode® - Polygenic risk assessment of coronary heart disease

LIPID inCode® - Prevention of heart disease, genetic diagnosis and risk assessment of familial (inherited) hypercholesterolemia

THROMBO inCode® - Genetic diagnosis and risk assessment of thrombophilia and thrombotic risk

SUDD inCode® - Genetic diagnosis and cause of sudden cardiac death and familial heart disease

ROCA® - Risk of Ovarian Cancer Algorithm ("ROCA")

The Group is scaling its commercial programmes across the US, UK, and Europe.

US Business

GENinCode's US strategy includes targeted test engagement of the top US physicians in preventive cardiology and lipidology. The Company continues to build partnerships with US key opinion leaders (KOLs) and major institutions, supported by education programmes using our 'SITAB' system (System of Integrated Traceability Analysis and Biology) to deliver polygenic risk scores and data registry capability. Our testing continues to expand across institutions, community clinics, and executive health settings.

The Company has now successfully onboarded over 45 top-tier institutional sites, mainly for the sale of LIPID inCode. Test volumes are anticipated to grow following the recent CARDIO inCode-Score Thermo Fisher collaboration and are expected to materially increase once FDA approval and expanded insurance coverage are received. The Total Addressable Market for CARDIO inCode is estimated at $10.5 billion, with a Serviceable Available Market of $4.5 billion. Initial market scoping indicates an addressable patient pool of approximately 21 million patients, of whom around 8.5 million likely to be prescribed CARDIO inCode-Score once covered by insurance.

Following progressive and ongoing discussions with the FDA, the Company is now finalising its updated CARDIO inCode-Score Coronary Artery Disease Polygenic Risk Score (CAD PRS) De Novo Pre Market submission. Discussions with the FDA were primarily focused on provision of further data around multi-ethnic population groups, statistical and medical review analysis to confirm the accuracy of the new clinical data to be submitted to FDA. The agreed study requirements to resolve these remaining deficiencies have been included in the new Kaiser Permanente study protocols with the clinical studies now ongoing and expected to complete over the next quarter in preparation for the new Pre Market submission to be filed in Q3.26.

US FDA approval of CARDIO inCode-Score (CAD PRS) would allow the test to be marketed nationally as a Medical Device, substantially expanding the potential market opportunity in the US.

In January 2025 CARDIO inCode-Score was included in the US Centres for Medicare and Medicaid Services (CMS) 2025 Clinical Lab Fee Schedule with a median price of $500 per test. This development marks an important step in facilitating reimbursement from Medicare and Medicaid across the US. In addition, the Company is preparing its MolDx submission for US state-based reimbursement.

In December 2025, GENinCode and Thermo Fisher Scientific signed a collaboration covering manufacturing, distribution and sales of CARDIO inCode-Score to laboratories across the US and Europe, Middle East and Africa (EMEA) regions. Prior to US FDA approval, laboratories are being introduced to CARDIO in-Score as an 'In House Assay' for the prevention of heart disease. Once FDA Medical Device approval is received, the collaboration will extend to manufacturing and sale of the Medical Device to laboratories and test centres across the US. A similar approach will be adopted in the EMEA market.

Thermo Fisher Scientific has been chosen as the preferred partner based on the design and development of the CARDIO inCode-Score (CAD PRS) test on Thermo Fisher's proprietary QuantStudio™ 5 Dx Real Time PCR System. The QuantStudio™ 5 Dx Real Time PCR System is globally available with significant installation coverage across the US and EMEA region. Increasing demand for CARDIO inCode-Score will be met by Thermo Fisher Scientific's scale up of the test manufacturing. Thermo Fisher Scientific is a major global provider of genetic reagents to labs with an installed QuantStudio (QS Dx) platform user base.

The Thermo Fisher collaboration is non-exclusive for a 3 Year term that is extendable. Sales and distribution will be conducted through Thermo Fisher Scientific's lab network with end pricing under discussion. GENinCode's core US products, CARDIO inCode and LIPID inCode, are US CLIA and CAP approved.

GENinCode has built a significant body of clinical evidence around the clinical utility of the CARDIO inCode-Score (CAD PRS). In March 2026, post period end, the American College of Cardiology and American Heart Association announced an update to the Dyslipidemia and Lipid Management guidelines which now includes coronary artery disease polygenic risk scores (CAD PRS) as a new risk assessment tool for the prevention of heart disease. We are delighted to see CAD PRS included in the US guidelines to improve coronary heart disease risk Calculation, Personalisation and Reclassification (CPR) to prevent heart disease.   

LIPID inCode is a leading test for Familial Hypercholesterolemia (FH) with increasing recognition by the US Centres for Disease Control (CDC) of the public health importance of testing to identify individuals suffering with FH as these individuals are at high risk of 'earlier in-life' onset of cardiovascular disease, in the form of atherosclerosis, angina or heart attack. LIPID inCode® has received reimbursement coding and medical classification coding (ICD-10) coverage in the US with an average insurance reimbursement of $1,229, reflecting the Clinical Laboratory Fee Schedule for the test and the broad Familial Hypercholesterolemia Panel of tests to identify FH genetic variants.

UK and Europe Business

In the UK, we continue to progress our NHS commercial collaboration to improve diagnosis and turnaround time for testing of Familial Hypercholesterolemia (FH) and for the prevention of heart disease using coronary artery disease (CAD) and cholesterol (LDL) polygenic risk scores at significantly reduced costs to the NHS. The LIPID inCode implementation in the North-East and North-Cumbria (Newcastle) has now resulted in GENinCode processing approximately 2,800 FH tests over the past 24 months enabling the region to meet the NHS 10 Year Plan. Importantly, the region is the only region in NHS England to meet the NHS 10 Year Plan for FH testing. FH genetic testing is critically important to diagnose patients in the population who are at high risk of heart disease and from these tests over 500 positive FH patients have been identified and diagnosed.

https://thehealthinnovationnetwork.co.uk/case_studies/genomic-testing-for-cardiovascular-conditions/

Whilst we have made great progress to support the NHS for FH diagnosis and cardiovascular disease prevention, future progress has been slowed by the major strategic, organisational and funding changes across the NHS.

There is continuing and growing demand for LIPID inCode in Spain and Italy and for the introduction of THROMBO inCode in public hospital labs.

We are progressing the CARDIO inCode-Score pilot studies in the Spanish regions of Catalonia and Extremadura. We tested approx. 900 individuals with the final results under review. The Catalonia region has a population of approx. 7.7 million, with an estimated 476,000 individuals at risk of a cardiovascular event e.g. heart attack.

The Extremadura region has a population of approx. one million, with an estimated 50,000 individuals at risk of a cardiovascular event. CARDIO inCode-Score is expected to change clinical practice by identifying those individuals at high genetic risk and improving preventive treatment.

In the EU our commercial products are CE-Marked, with CARDIO inCode, THROMBO inCode, and LIPID inCode generating revenues, primarily in Spain. Year-on-year revenue growth in Spain was driven by THROMBO inCode and LIPID inCode, supported by Spanish regions' Familial Hypercholesterolemia (FH) detection plans. The regional roll-out of CARDIO inCode-Score for cardiovascular prevention in primary care has contributed to growth, with the 2025 announcement of the Catalonia regional pilot implementation providing successful preliminary clinical results. Other pilots are underway in the Extremadura region and negotiations are ongoing in further Spanish regions including Andalucía, Basque region, and Baleares.

In Italy, direct business operations are expanding with partnerships such as Fondazione SISA supporting LIPID inCode. In Germany, LIPID inCode sales are strengthening through collaboration with Uniklinikum, leveraging the NHS model for implementation.

In December 2025, the Company entered into collaboration with Sohin Genetics, Mexico to distribute the CARDIO inCode-Score (CAD PRS) test for the prevention of coronary artery disease. Mexico has a population of over 130 million with an estimated cardiovascular disease market of USD$ 4.3 billion, with coronary artery disease the leading cause of death.

In October 2025, the Company entered into an agreement with University College London (UCL) to be the first trust to adopt the Risk of Ovarian Cancer Algorithm (ROCA) Test within the NHS. NICE draft guidelines recommend ROCA testing every four months for women at risk of ovarian cancer. Final NICE guidance was released in March 2024, officially recommending the test. Efforts are underway to roll out the ROCA test across several NHS regions with support from Cancer Alliances and Specialised Services. The test has gained strong backing from gynaecological oncologists, geneticists, and genetic counsellors.

International expansion of ROCA is progressing, with agreements signed in Switzerland and Austria in 2024, with plans to expand into Germany and Spain. The US market remains under evaluation, with ongoing considerations based on progress in the UK and Europe.

Intellectual Property

We maintain an ongoing intellectual property programme to strengthen our existing patent portfolio and advance our family of patents for both CARDIO inCode and THROMBO inCode. We will continue to build our intellectual property portfolio and actively evaluate in-licensing and acquisition opportunities as appropriate to enhance our competitive product positioning.

Financial review

In FY25, the Company saw year-on-year revenues increase 14% to £3.1m (2024: £2.7m), driven by growth across the UK, EU, and US businesses. The Company continues to scale its commercial programme across these core markets whilst maintaining tight control over its operational costs. Gross profit for the year was £1.8m (2024: £1.4m), with an improved margin of 59% (2024: 53%).

Administrative expenses increased to £6.7m (2024: £5.9m).  The year-on-year increase in Administrative costs reflects the extended commercial costs of selling and scaling the business, together with reduced R&D tax credits, gave rise to an increase in total comprehensive loss for the year of (£5.5m) (2024: (£4.3m)). The cash position at the end of December 2025 was £0.8m (2024: £1.1m). At the beginning of 2026, the Company successfully completed a £4.7m secondary placing on AIM to support its commercialisation and scale-up.

Capital Structure

The number of shares in issue at 31 December 2025 was 286,882,042. The loss per share for the year ending 31 December 2025 was 2.08p/share. The Board of Directors will not be recommending a dividend payment for the year ended 31 December 2025. Following the recent secondary placing completed in February 2026, the total number of ordinary shares in issue is 753,041,137.

Outlook

We expect to see revenues grow across the business over the coming year based on increasing sales volumes initially through the Thermo Fisher collaboration and subsequently, through the FDA Pre Marketing approval of CARDIO inCode-Score once it receives FDA approval. We are focused on commercial opportunities with leading US and EU labs and hospital institutions whilst maintaining readiness to develop our UK NHS relationship. Following progressive discussions with the FDA regarding CARDIO inCode-Score, we expect to submit our updated 'De Novo' Pre Market submission over the coming months. CARDIO inCode-Score approval represents a significant milestone and growth accelerator for the Company as a 'first in class' low cost, commercially available genetic test to prevent heart disease, the leading cause of death globally. Given the challenging markets, we will grow revenues whilst maintaining a tight control over operational costs to target a breakeven/profit position over the medium term. We expect to de-risk our business model whilst delivering strong growth across our core markets.

During 2026, the Company expects to complete the following key deliverables:

·    Increased Year-on-Year revenues and improving margins with a reduction in EBITDA losses moving towards breakeven

·    Commercial expansion of LIPID inCode and scale-up of CARDIO inCode

·    Implementation of LIPID inCode and CARDIO inCode testing in leading US healthcare institutions and State-based healthcare systems 

·    Progress FDA De Novo Pre Market submission for approval of CARDIO inCode-Score

·    Expansion of the MVZ Uniklinikum, Germany collaborative programme to provide LIPID inCode® testing for its patients

·    Growth of ROCA trust adoption in the NHS and expansion in EU

·    Continued strengthening of the commercial, marketing and selling teams to support revenue growth

We have a strong and growing competitive clinical advantage to identify patients at high genetic risk of coronary heart disease and to improve preventive care.

Commensurate with this growth we will build investment in our international manpower resources and expertise.

We continue to build our business and believe our tests are industry leading and will deliver significant investor returns. We would like to thank our investors, Board, management, and employees for their strength and determination in helping support and drive our business growth.

We look forward to updating our investors on our forthcoming progress.

Matthew Walls                                                 William Rhodes

Chief Executive Officer                                  Chairman

5 June 2026                                                         5 June 2026

Consolidated Income Statement for the Year Ended 31 December 2025

Notes 2025 2024
£'000 £'000
CONTINUING OPERATIONS
Revenue 4 3,076 2,701
Cost of sales (1,272) (1,275)
GROSS PROFIT 1,804 1,426
Administrative expenses (6,670) (5,873)
ADJUSTED EBITDA (4,866) (4,447)
Depreciation (163) (240)
Amortisation (103) (107)
Share based payment expense (761) (397)
Impairment loss - (149)
Reversal of contingent consideration provision - 206
OPERATING LOSS 5 (5,893) (5,134)
Other income 7 43 99
Finance charge 7 (13) (48)
LOSS BEFORE INCOME TAX 5 (5,863) (5,083)
Income tax 8 158 649
LOSS FOR THE YEAR (5,705) (4,434)
ATTRIBUTABLE TO:
Equity holders of the parent company (5,705) (4,434)
LOSS PER SHARE
Basic earnings per share (pence) 10 (2.08) (2.53)
Diluted earnings per share (pence) 10 (2.08) (2.53)

Consolidated Statement of Comprehensive Income 31 December 2025

Notes 2025

£'000
2024

£'000
LOSS FOR THE FINANCIAL YEAR (5,705) (4,434)
Other comprehensive income
Items that are or may be subsequently reclassified to the profit and loss:
Exchange differences on translation of foreign operations 198 132
OTHER COMPREHENSIVE INCOME FOR THE YEAR 198 132
TOTAL COMPREHENSIVE LOSS FOR THE YEAR (5,507) (4,302)

Consolidated Statement of Financial Position 31 December 2025

2025 2024
Notes £'000 £'000
ASSETS
NON-CURRENT ASSETS
Intangible assets 12 98 118
Property, plant and equipment 13 113 234
Right of use asset 14 124 207
TOTAL NON-CURRENT ASSETS 335 559
CURRENT ASSETS
Inventories 15 73 126
Trade and other receivables 16 1,074 813
Cash and cash equivalents 17 827 1,110
Financial assets 18 68 55
TOTAL CURRENT ASSETS 2,042 2,104
TOTAL ASSETS 2,377 2,663
EQUITY
SHAREHOLDERS' EQUITY
Called up share capital 19 2,869 1,770
Share premium 20 21,126 18,482
Foreign currency translation reserve 20 375 177
Share based payment reserve 21 1,404 643
Retained earnings 20 (25,650) (19,945)
TOTAL EQUITY 124 1,127
LIABILITIES
NON-CURRENT LIABILITIES
Lease liability 24 51 147
Deferred Tax 25 2 12
53 159
CURRENT LIABILITIES
Trade and other payables 22 2,105 1,290
Lease liability 24 95 87
2,200 1,377
TOTAL LIABILITIES 2,253 1,536
TOTAL EQUITY AND LIABILITIES 2,377 2,663

The financial statements were approved and authorised for issue by the Board of Directors on 5 June 2026 and were signed on its behalf by:

….......................................................

Paul Foulger

Director

Date: 5 June 2026

Company Statement of Financial Position 31 December 2025

2025 2024
Notes £'000 £'000
ASSETS
NON-CURRENT ASSETS
Investments 11 697 292
Intangible assets 12 98 118
Property, plant, and equipment 13 9 49
Right of use asset 14 124 207
TOTAL NON-CURRENT ASSETS 928 666
CURRENT ASSETS
Trade and other receivables 16 195 273
Cash and cash equivalents 17 500 669
TOTAL CURRENT ASSETS 695 942
TOTAL ASSETS 1,623 1,608
EQUITY
SHAREHOLDERS' EQUITY
Called up share capital 19 2,869 1,770
Share premium 20 21,126 18,482
Share based payment reserve 21 1,404 643
Retained earnings 20 (24,702) (20,063)
TOTAL EQUITY 697 832
LIABILITIES
NON-CURRENT LIABILITIES
Contingent consideration provision 24 - -
Lease liability 24 51 147
Deferred Tax 25 2 12
CURRENT LIABILITIES
Trade and other payables

Lease liability
22

24
778

95
530

87
TOTAL LIABILITIES 926 776
TOTAL EQUITY AND LIABILITIES 1,623 1,608

As permitted by Section 408 of the Companies Act 2006 GENinCode Plc has taken the exemption from presenting its unconsolidated profit and loss account.  The parent company's loss for the financial year was £4,639k (2024 - loss of £4,808k).

The financial statements were approved and authorised for issue by the Board of Directors on 5 June 2025 and were signed on its behalf by:

…...............................................

Paul Foulger

Director

5 June 2025

Consolidated Statement of Changes in Equity for the Year Ended 31 December 2025

Foreign Share
Called up Share Currency based
share premium Translation payment Retained Total
capital account Reserve reserve earnings equity
£'000 £'000 £'000 £'000 £'000 £'000
Balance at 1 January 2024 958 15,551 45 246 (15,511) 1,289
Changes in equity
Loss for the financial year - - - - (4,434) (4,434)
Other comprehensive income - - 132 - - 132
Total comprehensive (expense)/income - - 132 - (4,434) (4,302)
Share based payments - - - 397 - 397
Equity issue 812 2,931 - - - 3,743
Total transactions with owners, recorded directly in equity 812 2,931 - 397 - 4,140
Balance at 31 December 2024 1,770 18,482 177 643 (19,945) 1,127
Changes in equity
Loss for the financial year - - - - (5,705) (5,705)
Other comprehensive income - - 198 - - 198
Total comprehensive (expense)/income - - 198 - (5,705) (5,507)
Share based payments - - - 761 - 761
Equity issue 1,099 2,644 - - - 3,743
Total transactions with owners, recorded directly in equity 1,099 2,644 - 761 - 4,504
Balance at 31 December 2025 2,869 21,126 375 1,404 (25,650) 124

Company Statement of Changes in Equity for the Year Ended 31 December 2025

Called up Share
share Premium Share based payment Retained Total
capital account reserve earnings equity
£'000 £'000 £'000 £'000 £'000
Balance at 1 January 2024 958 15,551 246 (15,255) 1,500
Changes in equity
Loss for the financial year - - - (4,808) (4,808)
Total comprehensive (expense)/income - - - (4,808) (4,808)
Share based payments - - 397 - 397
Equity issue 812 2,931 - - 3,743
Total transactions with owners, recorded directly in equity 812 2,931 397 - 4,140
Balance at 31 December 2024 1,770 18,482 643 (20,063) 832
Changes in equity
Loss for the financial year - - - (4,639) (4,639)
Total comprehensive (expense)/income - - - (4,639) (4,639)
Share based payments - - 761 - 761
Equity issue 1,099 2,644 - - 3,743
Total transactions with owners, recorded directly in equity 1,099 2,644 761 - 4,504
Balance at 31 December 2025 2,869 21,126 1,404 (24,702) 697

Consolidated Statement of Cash Flows for the Year Ended 31 December 2025

2025 2024
£'000 £'000
Cash flows from operating activities
Loss before taxation (5,863) (5,083)
Adjustments for:
Impairment loss - 149
Reversal of contingent consideration provision - (206)
Depreciation and amortisation 266 347
Share based payments 761 397
Finance charges 13 48
Bank interest income (43) (99)
Operating cashflow before working capital changes (4,866) (4,447)
Cash used in operations
(Increase) in trade and other receivables (261) (231)
(Decrease) / Increase in trade and other payables 815 (1,077)
Decrease / (Increase) in inventory 53 (42)
(Increase) in financial assets (13) (13)
Income taxes received 148 637
Net cash outflow from operating activities (4,124) (5,173)
Investing activities
Purchase of property, plant, and equipment (44) (49)
Bank interest income 43 99
Net cash flows generated in investing activities (1) 50
Financing activities
Payments under lease liabilities (101) (98)
Proceeds from share issue 3,743 3,743
Net cash flows from financing activities 3,642 3,645
Net change in cash and cash equivalents (483) (1,478)
Cash and cash equivalents at the beginning of the year 1,110 2,484
Movement in retranslation 200 104
Cash and cash equivalents at the end of the year 827 1,110

Notes to the Consolidated Financial Statements for the Year Ended 31 December 2025

1.          Statutory information

GENinCode Plc is a public limited company, limited by shares, registered in England and Wales. The Company's registered number and registered office address can be found on the General Information page.

The Group's principal activity is the development and commercialisation of clinical genetic tests, to provide predictive analysis of risk to a patient's health based on their genes.

The consolidated financial statements comprised of the Company and its subsidiaries (together referred to as "the Group") as at and for the year ended 31 December 2025. The parent Company financial statements present information about the Company as a separate entity and not about its Group.

2.          Material accounting policies

Basis of preparation

The consolidated financial statements of the Group have been prepared using the historical cost convention, on a going concern basis and in accordance with UK-adopted international accounting standards ("IFRS") and the Companies Act 2006 applicable to companies reporting under IFRS, using accounting policies which are set out below and which have been consistently applied to all years presented, unless otherwise stated.

The financial statements of the Company have been prepared in accordance with Financial Reporting Standard 101 "Reduced Disclosure Framework" ('FRS 101') and the requirements of the Companies Act 2006. The Company will continue to prepare its financial statements in accordance with FRS 101 on an ongoing basis until such time as it notifies shareholders of any change to its chosen accounting framework.

In accordance with FRS 101, the Company has taken advantage of the following exemptions:

• Requirements of IAS 24, 'Related Party Disclosures' to disclose related party transactions entered into between two or more members of a group;

• the requirements of paragraphs 134(d) to 134(f) and 135(c) to 135(e) of IAS 36 Impairments of Assets;

• the requirements of IFRS 7 Financial Instruments: Disclosures;

• the requirements of paragraphs 10(d), 16, and 111 of IAS 1 Presentation of Financial Statements;

• the requirements of paragraphs 134 to 136 of IAS 1 Presentation of Financial Statements;

• the requirements of IAS 7 to prepare a Statement of Cash Flows.

New and amended standards adopted by the Group

The most significant new standards and interpretations adopted, none of which are considered material to the Group, are as follows:

Ref Title Summary Application date of standards (periods commencing)
IAS 21 Lack of Exchangeability Requirement for an entity to apply a consistent approach to assessing whether a currency is exchangeable into another currency and, when it is not, to determining the exchange rate to use and the disclosures to provide. 1 January 2025

New standards and interpretations not yet adopted

Unless material the Group does not adopt new accounting standards and interpretations which have been published and that are not mandatory for 31 December 2025 reporting periods.

No new standards or interpretations issued by the International Accounting Standards Board ('IASB') or the IFRS Interpretations Committee ('IFRIC') have led to any material changes in the Company's accounting policies or disclosures during each reporting period.

The most significant new standards and interpretations to be adopted in the future are as follows:

Ref Title Summary Application date of standards (periods commencing)
IFRS 9 and IFRS 7 Amendments to the Classification and Measurement of Financial Instruments Modifies the following requirements:

- Derecognition of financial liabilities: Settled through electronic transfers.

- Classification of financial assets:

Elements of interest in basic lending arrangements.

Contractual terms that change the timing or amount of contractual cash flows.

Financial assets with non-recourse features

Investments in contractually linked instruments.

- Disclosures

Investments in equity instruments designated at FVTOCI.

Contractual terms that could change the timing or amount of contractual cash flows.
1 January 2026
IFRS 18 Presentation and Disclosure in Financial Statements Introduction of overall principles for how information should be aggregated and disaggregated.

Disclosures related to management defined performance measures.
1 January 2027

Going concern

The financial statements have been prepared on the assumption that the Group and Company is a going concern. In making this assessment, the Directors have considered detailed budgets and forecasts for the next 12 months from the date of this report including the cash at bank available as at the date of approval of this report. The assessment includes assumptions relating to revenue growth which, if not met, means an additional fund raise may be required. The Directors are confident that the revenue targets will be met and if they are not, they have a proven track record in raising funds and therefore they are satisfied that the Group and Company should be able to meet its financial obligations as they fall due and have concluded it is appropriate to prepare the financial statements on a going concern basis.

The Directors have also taken into consideration that, on 9 February 2026, the Company issued 466,159,095 shares at a price of 1.0 pence per share as a result of a fund raising of £4.7m in capital for the Group. A total of 23,000,000 shares were issued to the Directors of the Group under the same terms.

Delays in revenue growth could have a potential impact on the Group's liquidity, however there are a number of potential mitigating actions that can be taken to safeguard the Group's cash position, including working capital controls and reductions in discretionary spending. The Group has an ongoing commitment to keep costs and working capital under control so that decreasing net losses can extend the cash runway and eventually drive the business towards generating positive cash flows.

Given there is uncertainty over the revenue forecasts and, if required, the timing and quantum of an additional fund raise cannot be predicted, these factors indicate the existence of a material uncertainty which may cast significant doubt about the Group and Company's ability to continue as a going concern and, therefore, that it may be unable to realise its assets and discharge its liabilities in the normal course of business. The financial statements do not include the adjustments that would result if the Group was unable to continue as a going concern.

Basis of consolidation

The Parent has 100% control of all subsidiaries. The subsidiaries consolidated in these Group accounts were acquired via group re-organisation in 2020 and as such merger accounting principles have been applied, except for the acquisition of Abcodia Limited in September 2022. The subsidiaries' financial figures are included for their entire financial year rather than from the date the company took control of them, with the exception of Abcodia Limited which was acquired in September 2022.

Inter-company transactions, balances, and unrealised gains on transactions between Group companies are eliminated during the consolidation process.

The Company acquired its 100% interest in Abcodia Ltd in September 2022.  The results of subsidiaries acquired during the year are included from the effective date of acquisition.  Where necessary, adjustments are made in results of subsidiaries to bring the accounting policies used into line with those used by the Group.

The subsidiary, Abcodia Limited is exempt from audit by virtue of s479A of the Companies Act 2006.

Property, plant, and equipment

Depreciation is provided to write off cost, less estimated residual values, of all property, plant, and equipment, evenly over their expected useful lives, calculated at the following rates:

Plant                                                 12%

Equipment                                       25%

Impairment

The carrying value of the property, plant and equipment is compared to the higher of value in use and the fair value less costs to sell. If the carrying value exceeds the higher of the value in use and fair value less the costs to sell the asset, then the asset is impaired, and its value reduced by recognising an impairment provision.

Intangible assets

(i)       Patents and licenses costs

The Group has purchased patents and licences since incorporation. The costs incurred in obtaining these patents and licenses have been capitalised. Amortisation is charged as follows:

Patents                                             Over estimated economic life of 10 years

Licences                                           20% (estimated useful life of 5 years)

The Patents and license costs are reviewed for impairment whenever events or changes in circumstances indicate that the carrying amount may not be recoverable.

(ii)      Software costs

The Group has purchased software since incorporation. The costs incurred in obtaining the software have been capitalised as the Group uses the software platform to provide results to its customers.

Amortisation is charged on a straight-line basis at 25% over the useful life of the related asset. Software costs are reviewed for impairment whenever events or changes in circumstances indicate that the carrying amount may not be recoverable.

Foreign currency

The functional currency of the Company is Sterling Pound (£) and its subsidiaries are in Euros (€) and US Dollars ($). The presentational currency of the Company is £.

Transactions entered by the Group's entities in a currency other than the functional currency are recorded at the rates ruling when the transactions occur. Foreign currency monetary assets and liabilities are translated at the rates ruling at the statement of financial position date. Exchange differences arising on the re-translation of outstanding monetary assets and liabilities are also recognised in the income statement. The subsidiaries profit and loss are translated at average rate and the balance sheet is translated at the year end rate.

The exchange rates used in the financial statements are as follows:

2025 2024
Sterling/euro exchange rates
Average exchange rate for the year 1.167 1.181
Exchange rate at the year end 1.147 1.209
Sterling/US dollar exchange rates
Average exchange rate for the year 1.317 1.278
Exchange rate at the year end 1.347 1.252

Cash and cash equivalents

Cash and cash equivalents include cash in hand and deposits held on call, together with other short term highly liquid investments which are not subject to significant changes in value and have original maturities of less than three months.

Revenue recognition

Revenue is recognised in accordance with the requirements of IFRS 15 'Revenue from Contracts with Customers'. The Group recognises revenue to depict the transfer of promised goods and services to customers in an amount that reflects the consideration to which the entity expects to be entitled in exchange for those goods or services. Revenue is determined to be recognised at the point of despatch of the product or service unless there are specific provisions in the relevant contract. Revenue from the provision of testing and reporting services is recognised upon delivery of the report to the customer. Invoices are typically raised upon delivery of the products or reporting services, unless there is a different contractual requirement, for payment according to credit terms, the prices having been pre-agreed on a product and customer basis.

In the US, there is an additional factor which management takes into consideration in that if a test is payable by an Insurance company, then the test is billed at a pre-agreed rate according to the CPT (Current Procedural Terminology) code for this type of test as identified by the Centers for Medicare and Medicaid Services (CMS). Once the test has been taken by the patient, the insurance company will then be pursued for payment, albeit this could take weeks or months as negotiation around the final price will ensue, especially in these early days whilst the company is a new 'out-of-network' provider of testing. Recognition of revenue is as follows:

·      All revenue under self-pay is recognised once the payment has been received and the physician/customer has received their test results

·      In the case of patients undertaking the Insurance route, as it is not known what the final agreed price per test will be, management estimates what percentage of the billed amounts is likely to be actually paid; this percentage is based on any receipts we have received to date. Going forward, once the test is more established in the market, then it will be easier to predict what this final payment is likely to be per test.

Equity

Share capital and share premium

Share capital account represents the nominal value of all share issues. The share premium account represents the excess of proceeds over the nominal value for all share issues, including the excess of the exercise price over the nominal value of the shares.

Retained deficit

Retained deficit are the consolidated retained funds and share based payments reserve for the group or company.

Foreign exchange reserve

The foreign exchange reserve is accumulated reserves created by Foreign Exchange differences on the consolidation of Group balances into the reporting currency of pounds sterling.

Employee benefits

(i)       Short-term benefits

Wages, salaries, paid annual leave and sick leave, bonuses and non-monetary benefits are accrued in the year in which the associated services are rendered by employees of the Company.

Employee benefit costs

The Group operates a defined contribution pension scheme.  Contributions payable to the Group's pension scheme are charged to the income statement in the year to which they relate.

Research and development expenditure

Expenditure on research activity is recognised as an expense in the year in which it is incurred.

Share based payment

The fair value of equity-settled share-based payments to employees is determined at the date of grant and expensed on a straight line basis over the vesting period based on the Group's estimate of shares or options that will eventually vest. 

All equity-settled share-based payments are ultimately recognised as an expense in the profit or loss with a corresponding credit to the Share based payment reserve.  If vesting periods or other non-market vesting conditions apply, the expense is allocated over the vesting period, based on the best available estimate of the number of share options expected to vest. Estimates are subsequently revised if there is any indication that the number of share options expected to vest differs from previous estimates. Any cumulative adjustment prior to vesting is recognised in the current period. No adjustment is made to any expense recognised in prior periods if share options ultimately exercised are different to that estimated on vesting.

Share options granted to employees of subsidiaries are recognised as an expense in the employing subsidiary and as an addition to the investment in the subsidiary for the parent company.  The costs are calculated on the same basis as above and are included upon consolidation. 

Upon exercise of share options, the proceeds received net of attributable transaction costs are credited to share capital, and where appropriate share premium.

Leased assets

The Group recognises a right of use asset and a lease liability at the lease commencement date. The right of use asset is initially measured at cost, which comprises of the initial amount of the lease liability adjusted for any lease payments made at or before the commencement date, plus any initial direct costs incurred and an estimate of costs to dismantle and remove the underlying asset or to restore the underlying asset or to restore the underlying asset or the site on which it is located, less any lease incentives received.

The right of use asset is subsequently depreciated using the commencement date to the end of the lease term.

The lease liability is initially measured at the present value of the lease payments that are paid at the commencement date, discounted using the Group's incremental borrowing rate.

The lease liability is measured at amortised cost using the effective interest method. It is re-measured when there is a change in future lease payments arising from a change in an index or rate.

The Group has elected not to recognise right of use assets and lease liabilities for short term leases that have a lease term of 12 months or less and leases of low value assets. The Group recognises the lease payments associated with these leases as an expense on a straight-line basis over the lease term.

Financial instruments

IFRS 9 requires an entity to address the classification, measurement and recognition of financial assets and liabilities.

a)       Classification

The Group classifies its financial assets in the following measurement categories:

•        those to be measured subsequently at fair value (either through OCI or through profit or loss); and

•        those to be measured at amortised cost.

The classification depends on the Group's business model for managing the financial assets and the contractual terms of the cash flows.

For assets measured at fair value, gains and losses will be recorded either in profit or loss or in OCI.

The entity will recognise a financial liability in its statement of financial position when it becomes party to the contractual provisions of the instrument. At initial recognition, the entity measures a financial liability at its fair value plus or minus, in the case of a financial liability not at fair value through profit or loss, transaction costs that are directly attributable to the acquisition or issue of the financial liability.

The Group classifies financial assets as amortised costs only if both of the following criteria are met:

•        the asset is held within a business model whose objective is to collect contractual cash flows; and

•        the contractual terms give rise to cash flows that are solely payment of principal and interest.

b) Recognition

Purchases and sales of financial assets are recognised on trade date (that is, the date on which the Group commits to purchase or sell the asset). Financial assets are de-recognised when the rights to receive cash flows from the financial assets have expired or have been transferred and the Group has transferred substantially all the risks and rewards of ownership.

c) Measurement

At initial recognition, the Group measures a financial asset at its fair value plus, in the case of a financial asset not at fair value through profit or loss (FVPL), transaction costs that are directly attributable to the acquisition of the financial asset.

Transaction costs of financial assets carried at FVPL are expensed in profit or loss.

Debt instruments

Amortised cost: Assets that are held for collection of contractual cash flows, where those cash flows represent solely payments of principal and interest, are measured at amortised cost. Interest income from these financial assets is included in finance income using the effective interest rate method. Any gain or loss arising on derecognition is recognised directly in profit or loss and presented in other gains/(losses) together with foreign exchange gains and losses. Impairment losses are presented as a separate line item in the statement of profit or loss.

d) Impairment

The Group assesses, on a forward-looking basis, the expected credit losses associated with any debt

instruments carried at amortised cost. The impairment methodology applied depends on whether there has been a significant increase in credit risk. For trade receivables, the Group applies the simplified approach permitted by IFRS 9, which requires expected lifetime losses to be recognised from initial recognition of the receivables.

Inventory

Inventories are stated at the lower of cost and net realisable value. Cost comprises direct materials and, where applicable, direct labour costs and those overheads that have been incurred in bringing the inventories to their present location and condition. Cost is calculated using the weighted average cost method. Net realisable value represents the estimated selling price less all estimated costs of completion.

Taxation

Current and deferred tax is charged or credited in profit or loss, except when it relates to items charged or credited directly to equity, in which case the related tax is also dealt with in equity. Current tax is calculated on the basis of the tax laws enacted or substantively enacted at the reporting date in the countries where the Company and its subsidiaries operate.

Deferred tax liabilities are generally recognised for all taxable temporary differences and deferred tax assets are generally recognised for all deductible temporary differences to the extent that it is probable that taxable profits will be available against which those deductible temporary differences can be utilised, except for differences arising on investments in subsidiaries where the Group is able to control the timing of the reversal of the difference and it is probable that the difference will not reverse in the foreseeable future.

Recognition of the deferred tax assets is restricted to those instances where it is probable that a taxable profit will be available against which the difference can be utilised.

Deferred tax is calculated based on rates enacted or substantively enacted at the reporting date and expected to apply when the related deferred tax asset is realised, or liability settled.

Current taxes are based on the results shown in the financial statements and are calculated according to local tax rules, using tax rates enacted or substantially enacted by the statement of financial position date.

Critical accounting estimates and judgements

The preparation of financial information in conformity with IFRS requires the use of certain critical accounting estimates. It also requires the Directors to exercise their judgement in the process of applying the accounting policies which are detailed above. These judgements are continually evaluated by the Directors and management and are based on historical experience and other factors, including expectations of future events that are believed to be reasonable under the circumstances.

The key estimates and underlying assumptions concerning the future and other key sources of estimation uncertainty at the statement of financial position date, that have a significant risk of causing a material adjustment to the carrying amounts of assets and liabilities within the next financial year are reviewed on an ongoing basis. Revisions to accounting estimates are recognised in the year in which the estimate is revised if the revision affects only that year, or in the years of the revision and future periods if the revision affects both current and future years.

The estimates and judgements which have a significant risk of causing a material adjustment to the carrying amount of assets and liabilities within the next financial year are discussed below:

•        Share based payments

The Company has issued share options as an incentive to certain senior management. The fair value of options granted is recognised as an expense with a corresponding credit to the share-based payment reserve. The fair value is measured at grant date and spread over the year during which the awards vest.

For equity-settled share-based payment transactions, the goods or services received and the corresponding increase in equity are measured directly at the fair value of the goods or services received, unless that fair value cannot be estimated reliably. If it is not possible to estimate reliably the fair value of the goods or services received, the fair value of the equity instruments granted as calculated using the Black-Scholes model is used as a proxy. 

The fair value of share-based payments is measured by use of valuation models, which take into account conditions attached to the vesting and exercise of the equity instruments. The expected life used in the model is adjusted; based on management's best estimate, for the effects of non-transferability, exercise restrictions and behavioural considerations. The share price volatility percentage factor used in the calculation is based on historical share price performance of a group of peer companies as historical share price performance was not available for the Company on the date of grant.

The charge related to equity-settled transactions with employees is measured by reference to the fair value of the equity instruments at the date they are granted, using an appropriate valuation model selected according to the terms and conditions of the grant. There are two pricing models; being the Black Scholes model or the Monte Carlo model. The simplest option pricing model is the Black-Scholes model, which tends to be suitable for simple forms of share awards, in particular where there are no market-based performance conditions. Judgement is applied in determining the most appropriate valuation model and estimates are used in determining the inputs to the model. The group engaged a third-party expert to value the options granted using the Black-Scholes Model. Further disclosure of inputs relevant to the calculations is set out in Note 22.

·        Contingent consideration

Contingent consideration is a financial liability recorded at fair value (note 24). The amount of contingent consideration to be paid is based on the occurrence of future events, such as the achievement of certain development, regulatory and sales milestones. Accordingly, the estimate of fair value contains uncertainties as it involves judgment about the likelihood and timing of achieving these milestones as well as the discount rate used.

Changes in fair value of the contingent consideration obligation result from changes to the assumptions used to estimate the probability of success for each milestone, the anticipated timing of achieving the milestones and the discount period and rate to be applied. A change in any of these assumptions could produce a different fair value, which could have a material impact on the results from operations.

·        Carrying value of inter- company debtors

Management uses their judgement to assess the recoverability and value of intercompany debts, the Company has funded its subsidiaries (note 17) to assist with their growth.  Management have decided to provide for the inter-company debts in their entirety at the year end.  This is based on current forecasts and the ability of the subsidiaries to repay the debts within the foreseeable future.

·        US revenue recognition

Revenue is recognised in accordance with the requirements of IFRS 15 'Revenue from Contracts with Customers'. The Group recognises revenue to depict the transfer of promised goods and services to customers in an amount that reflects the consideration to which the entity expects to be entitled in exchange for those goods or services.

Revenue is determined to be recognised at the point of despatch of the product or service unless there are specific provisions in the relevant contract. Revenue from the provision of testing and reporting services is recognised upon delivery of the report to the customer. Invoices are typically raised upon delivery of the products or reporting services, unless there is a different contractual requirement, for payment according to credit terms, the prices having been pre-agreed on a product and customer basis.

In the US, there is an additional factor which management takes into consideration in that if a test is payable by an Insurance company, then the test is billed at a pre-agreed rate according to the CPT (Current Procedural Terminology) code for this type of test as identified by the Centers for Medicare and Medicaid Services (CMS). Once the test has been taken by the patient, the insurance company will then be pursued for payment, albeit this could take weeks or months as negotiation around the final price will ensue, especially in these early days whilst the company is a new 'out-of-network' provider of testing.

Revenues from Self-Pay patients and Institutions tend to be recognised 100%; however, in the case of patients undertaking the Insurance route, as it is not known what the final agreed price per test will be, management estimates what percentage of the billed amounts is likely to be actually paid; this percentage is based on any receipts we have received to date or any allocations against the patients' deductibles agreed by the Insurer. Going forward, once the test is more established in the market, then it will be easier to predict what this final payment is likely to be per test.

3.         Financial risk management

The Group's risk management is controlled by the board of directors.  The board identifies, evaluates, and mitigates financial risks across the Group.  Financial risks identified and how these risks could affect the Group's future financial performance are listed below:

Financial instruments by category

Financial assets at amortised cost 2025 2024
£'000 £'000
Cash and cash equivalents 827 1,110
Trade receivables 857 540
Financial assets 68 55
Other receivables 37 37
Financial assets at amortised cost 1,788 1,742
Financial liabilities at amortised cost 2025 2024
£'000 £'000
Trade payables 1,278 612
Accruals 603 510
Lease liability 146 234
Other payables 6 6
Financial liabilities at amortised costs 2,033 1,362

Fair value hierarchy

All the financial assets and financial liabilities recognised in the financial statements which are short-term in nature are shown at the carrying value which also approximates the fair values of those short-term financial instruments. Therefore, no separate disclosure for fair value hierarchy is required for them. The disclosure on fair value hierarchy does not apply to the financial leases.

The Group's activities expose it to a variety of financial risks, mainly credit risk, liquidity risk and interest rate risk.

Credit risk

Credit risk refers to the risk that a counterparty will default on its contractual obligations resulting in financial loss to the Group. In order to minimise this risk the Group endeavours only to deal with companies which are demonstrably creditworthy.

The aggregate financial exposure is continuously monitored. The Group's exposure to credit risk on cash and cash equivalents is considered low as the bank accounts are with banks with high credit ratings.

Liquidity risk

The Group currently holds cash balances to provide funding for normal activity and is managed centrally. Trade and other payables are monitored as part of normal management routine.

Interest rate risk

The Group's interest-bearing assets comprise of only cash and cash equivalents. As the Group's interest-bearing assets do not generate significant amounts of interest, changes in market interest rates do not have any significant direct effect on its income. 

The maturity of borrowings and other financial liabilities (representing undiscounted contractual cash-flows) is as follows:

2024 Within 1 Year
£'000
Trade and Other payables 1,128
Lease liability 100
Total 1,228
Over 1 Year
Trade and Other payables -
Lease liability 153
153
2025 Within 1 Year
£'000
Trade and Other payables 1,887
Lease liability 102
Total 1,989
Over 1 Year
Trade and Other payables -
Lease liability 52
52

Capital risk management

The Group's capital management objectives are to ensure the Group's ability to continue as a going concern, and provide an adequate return to shareholders by pricing products and services commensurate with the level of risk.

To meet these objectives, the Company reviews the budgets and forecasts on a regular basis to ensure there is sufficient capital to meet the needs of the Company through to profitability and positive cash flow.

All working capital requirements are financed from existing cash resources.

4.          Operating segments

There is only one operating segment. The Group has disaggregated revenue into various geographic regions in the following table.

2025 2024
£'000 £'000
Revenue from sale of kits and provision of support services 3,002 2,701
Primary Geographic Markets
Spain 2,105 1,897
UK 538 588
US 155 143
Italy 187 -
Germany 87 73
Rest of World 4 -
Total revenue per geographical markets 3,076 2,701

4.          Operating segments (continued)

2025 2024
£'000 £'000
Non-current assets
Primary Geographic Markets
Spain 104 70
UK 231 374
US - 115
Total non-current assets per geographical markets 335 559

5.   Loss from operations

2025 2024
£'000 £'000
Loss is stated after charging:
Cost of inventory 983 1,138
Staff costs 2,667 2,425
Royalty expense 124 189
Operating expenses-- External services 169 127
Directors' salaries and fees 844 603
Research expenditure 197 145
Depreciation and amortisation 266 347

5a. Auditor's remuneration

2025 2024
£'000 £'000
Fees payable to the company's auditor for the audit of the company's annual accounts 52 50
Fees payable to the subsidiary company's auditor for the audit of their annual accounts 4 4
Total 56 54

6.     Employees and directors

The average number of employees (including directors) in the Group during the year was made up as follows:

2025 2024
Number Number
Directors (including non-executive directors) 7 7
Employees 39 36
Total 45 42

The cost of employees (including directors) during the year was made up as follows:

2025 2024
£'000 £'000
Salaries and wages (including directors) 2,980 2,644
Social security costs 478 477
Employee benefits in kind 23 21
Pension costs 30 23
Share based payment expense 761 397
Total 4,272 3,562

Key management personnel compensation

The compensation of key management personnel, principally directors of GENinCode Plc for the year were as follows:

2025 2024
£'000 £'000
Directors' salaries 758 528
Social security costs 99 56
Pension costs 19 11
Directors' fees 86 75
Share based payment expense 404 170
Total 1,366 840

The above remuneration of directors includes the following amounts paid to the highest paid Director:

2025 2024
£'000 £'000
Highest paid Director 383 233

Amounts disclosed for the highest paid director exclude employers pension contributions and share based payments.                

7.         Other income

2025 2024
£'000 £'000
Bank interest income 43 98
Other revenue - 1
Total 43 99

Finance cost

2025 2024
£'000 £'000
Discount of lease liability 13 21
Unwinding contingent consideration - 27
Total 13 48

8.          Income tax

2025 2024
£'000 £'000
Current tax credit
R&D tax credit 148 637
Total current tax 148 637
Deferred tax
Accelerated capital allowances 10 12
Total current tax 10 12
Total tax (charge)/credit 158 649

The charge for the year can be reconciled to the loss in the consolidated statement of comprehensive income as follows:

2025 2024
£'000 £'000
Loss before taxation (5,863) (5,083)
Expected tax credit at the UK corporation tax rate of 25% (2024: 25%) (1,466) (1,270)
Current year losses carried forward 1,366 1,207
Capital allowances - (1)
Losses utilised - 12
Expenses disallowed for tax 100 77
Non-trade relationship - (25)
Accelerated Capital Allowances 10 12
R&D tax credit 148 637
Total tax (charge)/credit 158 649

Factors affecting current and future taxation

The Company has unrelieved tax losses carried forward of £6,666,414 (2024: £4,703,098). These have not been recognised as a deferred tax asset as there is currently insufficient evidence that the asset will be recoverable in the foreseeable future.

9.          Profit of parent company

As permitted by Section 408 of the Companies Act 2006, the income statement of the parent company is not presented as part of these financial statements.  The parent company's loss for the financial year was £4,638,978 (2024 - loss of £4,807,710).

10.        Earnings per share

Basic earnings per share is calculated by dividing the earnings attributable to ordinary shareholders by the weighted average number of ordinary shares outstanding during the year.

Diluted earnings per share is calculated using the weighted average number of shares adjusted to assume the conversion of all dilutive potential ordinary shares.

Reconciliations are set out below.

2024
Earnings Weighted average number of shares Per-share amount
£'000 pence
Basic EPS
Earnings attributable to ordinary shareholders (4,434) 175,023,256 (2.53)
Diluted EPS
Adjusted earnings (4,434) 175,023,256 (2.53)
2025
Earnings Weighted average number of shares Per-share amount
£'000 pence
Basic EPS
Earnings attributable to ordinary shareholders (5,705) 274,347,963 (2.08)
Diluted EPS
Adjusted earnings (5,705) 274,347,963 (2.08)

The Company had options issued over 31,619,190 (2024: 19,205,630) ordinary shares.

Due to the losses incurred from continuing operations in the years reported, there is no dilutive effect from the existing share options.

11.        Investments

Company

£'000
Cost
At 1 January 2024 231
Share based payments 211
Impairment (148)
At 31 December 2024 292
Share based payments 405
Impairment -
As at 31 December 2025 697

Share based payments relate to costs of employee options in the Company for employees of its subsidiary.

Summary of subsidiaries held in investments;

Name of entity Country of incorporation Ownership held Principal activities Registered office
Holding 2025 and 2024
GENinCode S.L.U. Spain Ordinary shares 100% Medical and scientific research Rambla d'Egara 235, 5ª planta C D, Terrassa 08224, Spain
GENinCode U.S. INC. USA Ordinary shares 100% Medical and scientific research 1209 Orange St., Wilmington Delaware 19801
GENinCode UK Ltd England & Wales Ordinary shares 100% Dormant company 1 St. Peters Square, Manchester, M2 3DE
Abcodia Ltd England & Wales Ordinary shares 100% Medical and scientific research 1 St. Peters Square, Manchester, M2 3DE
Abcodia UK Ltd England & Wales Ordinary shares 100%- Indirectly through Abcodia Ltd Dormant company 1 St. Peters Square, Manchester, M2 3DE
Abcodia CS Ltd England & Wales Ordinary shares 100%- Indirectly through Abcodia Ltd Dormant company 1 St. Peters Square, Manchester, M2 3DE
Abcodia Inc USA Ordinary shares 100%- Indirectly through Abcodia Ltd Dormant company 1209 Orange St., Wilmington Delaware 19801

12.             Intangible assets

Group

Software Patents & Licences Total
£'000 £'000 £'000
Cost
At 1 January 2024 52 203 255
Movement on retranslation (2) - (2)
At 31 December 2024 50 203 253
Movement on retranslation 3 - 3
At 31 December 2025 53 203 256
Amortisation
At 1 January 2024 52 65 117
Charge for the year - 20 20
Movement on retranslation (2) - (2)
At 31 December 2024 50 85 135
Charge for the year - 20 20
Movement on retranslation 3 - 3
At 31 December 2025 53 105 158
Net book value
At 31 December 2024 - 118 118
At 31 December 2025 - 98 98

12.             Intangible assets (continued)

Company
Patents & Licences
£'000
Cost
At 31 December 2024 203
At 31 December 2025 203
Amortisation
At 1 January 2024 65
Charge for the year 20
At 31 December 2024 85
Charge for the year 20
At 31 December 2025 105
Net book value
At 31 December 2024 118
At 31 December 2025 98

13.              Property, Plant and Equipment

Group Plant Office equipment Total
£'000 £'000 £'000
Cost
At 1 January 2024 35 732 767
Additions 30 19 49
Movement on retranslation (2) 7 5
At 31 December 2024 63 758 821
Additions 40 4 44
Movement on retranslation 3 (34) (31)
At 31 December 2025 106 728 834
Depreciation
At 1 January 2024 6 336 342
Charge for the year 4 235 239
Movement on retranslation - 6 6
At 31 December 2024 10 577 587
Charge for the year 8 155 163
Movement on retranslation 1 (30) (29)
At 31 December 2025 19 702 721
Net book value
At 31 December 2024 53 181 234
At 31 December 2025 87 26 113

13.              Property Plant and Equipment (continued)

Company Office Equipment
£'000
Cost
At 31 December 2024 214
Additions -
At 31 December 2025 214
Depreciation
At 31 December 2024 165
Charge for the year 40
At 31 December 2025 205
Net book value
At 31 December 2024 49
At 31 December 2025 9

14.              Right of use assets

Group Right of use asset: Buildings
£'000
Cost
As at 1 January 2024 402
Addition related to the incremental payment 12
At 31 December 2024 414
At 31 December 2025 414
Depreciation
Charge for the year 87
At 31 December 2024 207
Charge for the year 83
At 31 December 2025 290
Net book value
At 31 December 2024 207
At 31 December 2025 124
Company Right of use asset: Buildings
£'000
Cost
As at 1 January 2024 402
Addition related to the incremental payment 12
At 31 December 2024 414
At 31 December 2025 414
Depreciation
Charge for the year 87
At 31 December 2024 207
Charge for the year 83
At 31 December 2025 290
Net book value
At 31 December 2024 207
At 31 December 2025 124

15.              Inventory                             

Group
2025 2024
£'000 £'000
Inventory 73 126
Total 73 126

In 2025, a total of £983k (2024: £1,138k) of inventories was included in profit and loss as an expense as part of cost of sales.

16.              Trade and other receivables

Group
2025 2024
£'000 £'000
Trade receivables 857 540
Other receivables 91 70
Prepayments 126 203
Total 1,074 813
Company
2025 2024
£'000 £'000
Trade receivables 38 160
Intercompany receivables 16,564 14,521
Provision for credit loss on Intercompany receivables (16,564) (14,521)
Other receivables 89 68
Prepayments 68 45
Total 195 273

The inter-company loans above have been provided for in full as per IFRS 9 recognition requirements for credit losses.  Although the Board is confident that all inter-company loans will be collectible in the future, taking into account short term projections, the Board does not have sufficient evidence at the year-end that this will definitely be the case and hence takes a cautious approach in its accounting provisions.

General terms for settlement of debt with clients are 30 days from the date of invoice for private entities and 60 days with public entities.  The carrying value of trade and other receivables classified at amortised cost approximates fair value.

17.              Cash and cash equivalents

Group
2025 2024
£'000 £'000
Total 827 1,110
Company
2025 2024
£'000 £'000
Total 500 669

Where cash at bank earns interest, interest accrues at floating rates based on daily bank deposit rates.

The fair value of the cash & cash equivalent is as disclosed above. For the purpose of the cash flow statement, cash and cash equivalents comprise of the amounts shown above.

18.              Financial assets

Group
2025 2024
£'000 £'000
Financial assets 68 55
Total 68 55

The Financial assets relate to Spanish ring-fenced money for Tender bids and office rent.

19.             Share capital

2025 2024
£'000 £'000
286,882,042 Ordinary shares of £0.01 (2024: 176,964,426) 2,869 1,770
Total 2,869 1,770
As at 1 January 2025 1,770
Issued during the year 1,099
At 31 December 2025 2,869

On 3 March 2025 the Company issued 109,917,616 shares at a price of 3.7 pence per share as a result of a fund raising of £4.1m in capital for the Group. A total of 4,662,162 shares were issued to the Directors of the Group under the same terms.

On 26 March 2025, the Company announced that it had approved and granted (on 21 March 2025) new options over an aggregate of 14,028,305 new ordinary shares of 1 pence each in the Company to certain directors and employees of the Company, representing 4.89 per cent. of the Company's existing share capital; the new options have an exercise price of 3.7 pence per share and are exercisable on the second anniversary of the date of grant.  Following the grant of the new options and the options lapsed, there are options over a total of 32,915,560 ordinary shares in the Company.

The Company issued 4,662,162 ordinary shares to the Directors during the year under the same terms as the placing.

20.              Reserves

The following describes the nature and purpose of each reserve within equity:

Share capital Amount subscribed for share capital fully paid.
Retained earnings Retained earnings represents all other net gains and losses and transactions with shareholders (example dividends) not recognised elsewhere.
Share premium Excess subscribed above nominal value of shares. Included within share premium are share issue costs which relate to commissions and other directly attributable costs.
Foreign currency translation reserve This represents the net effect of translation of the subsidiaries whose functional currencies are EUR and USD into GBP the reporting currency.
Share based payment reserve This reserve comprises the fair value of options share rights recognised as an expense. Upon exercise of options or performance share rights, any proceeds received are credited to share capital and where appropriate share premium.

21.              Share based payments

The Company has issued share options as an incentive to certain senior management.  All share options granted during the year were granted under individual agreements and are subject to service vesting conditions. The exercise price is 3.7 pence on 14,028,305 shares.

Each share option converts into one ordinary share of GENinCode plc on exercise and are accounted for as equity-settled share-based payments. The equity instruments granted carry neither rights to dividends nor voting rights.

No. options Weighted average exercise price (pence)
Balance as at 31 December 2024 19,205,630 7.86
Granted in 2025 14,028,305 3.70
Lapsed in 2025 (318,375) 7.78
Unallocated 75,875 -
Balance as at 31 December 2025 32,991,435 6.02
Exercisable at 31 December 2025 - -
No. options Weighted average exercise price (pence)
Balance as at 31 December 2023 7,207,500 16.61
Surrendered in 2024 (6,984,500) 16.61
Lapsed in 2024 (398,000) 10.00
Granted in 2024 8,642,500 5.00
Granted in 2024 10,738,130 10.00
Balance as at 31 December 2024 19,205,630 7.86
Exercisable at 31 December 2024 - -

The vesting conditions for all options is up to 24 months and there are no market conditions which apply.

The value of share based payments charged to administrative expenses was £760,745 (2024, £397,456).

Employers' national insurance relating to the share based options has been accrued amounting to £49,037 (2024: £50,742).

The share-based payment charge was calculated and recognised over the vesting period of the relevant options.

The fair value is estimated at the date of grant using the Black-Scholes pricing model, taking into account the terms and conditions attached to the grant. The following are the inputs to the model for the equity instruments granted during the period:

Expected life 10 years
Expected Volatility 102.1%
Risk-free interest rate 4.71%
Share price at grant 3.1p
Fair value per award 2.8p

On 21 March 2025, the Company announced that it had approved and granted new options over an aggregate of 14,028,305 new ordinary shares of 1 pence each in the Company to certain directors and employees of the Company, representing 4.89% of the Company's existing share capital. The new options have an exercise price of £0.037 and are exercisable on the second anniversary of the date of the grant.

22.              Trade and other payables

Group
2025 2024
£'000 £'000
CURRENT
Trade payables 1,278 612
Accruals 604 510
Other tax payable 217 157
Other payables 6 11
Total 2,105 1,290
Company
2025 2024
£'000 £'000
CURRENT
Trade payables 342 141
Accruals 402 350
Tax payable 28 29
Other payables 6 10
Total 778 530

General terms for settlement of debt are 60 days in general, after the invoice has been remitted from supplier.

The carrying value of trade and other payables classified at amortised cost approximates fair value.

23.              Contingent consideration

Group
2025 2024
£'000 £'000
NON-CURRENT
Contingent consideration - -
Total - -
Company
2025 2024
£'000 £'000
NON-CURRENT
Contingent consideration - -
Total - -

The contingent consideration relates to the acquisition of Abcodia Limited which has a deferred consideration of up to £1m, payable to the vendors subject to the achievement of an EBIT of £1m generated by the sale of ROCA tests in the UK during the 6-year period following the date of acquisition. This is payable in two tranches; the first tranche of £350,000 is payable on the achievement of an EBIT of £350,000, and the second tranche of £650,000 is payable on the achievement of a further £650,000 of EBIT.  Contingent consideration has been calculated on the basis of only the first tranche of £350,000 being payable to the vendors, discounted to a present value of £178,000 using a rate of 15.3%.

24.              Lease liability

Maturity analysis- contractual undiscounted cash flows:

Group
2025 2024
£'000 £'000
Less than one year (undiscounted) 102 100
One to five years (undiscounted) 52 153
More than 5 years (undiscounted) - -

Lease liability included in the financial statements:

Group
2025 2024
£'000 £'000
NON-CURRENT
Lease liability 51 147
Total 51 147
CURRENT
Lease liability 95 87
Total 95 87

Maturity analysis- contractual undiscounted cash flows:

Company
2025 2024
£'000 £'000
Less than one year (undiscounted) 102 100
One to five years (undiscounted) 52 153
More than 5 years (undiscounted) - -

Lease liability included in the financial statements:

Company
2025 2024
£'000 £'000
NON-CURRENT
Lease liability 51 147
Total 51 147
CURRENT
Lease liability 95 87
Total 95 87
Lease liability reconciliation:
2025
£'000
Total balance brought forward 234
Payments (101)
Interest 13
Total balance carried forward 146

An interest expense of £12,908 with regards to the lease liability has been included in the accounts (2024: £20,358). A discount rate of 7.5% is used in the calculation of the liability and right of use asset. The lease term is 5 years ending in August 2027.

25.              Provisions and contingencies

Group
2025 2024
£'000 £'000
Deferred tax 2 12
Total 2 12
Company
2025 2024
£'000 £'000
Deferred tax 2 12
Total 2 12

Deferred tax relates to accelerated capital allowances.

26.              Capital commitments

There is no capital expenditure contracted at this year-end reporting.

27.              Related Party Transactions

During the year the Group and Company entered into the following transactions with related parties:

2025 2024
Related party Transaction £'000 £'000
Felix Frueh Fees, £2,500 was outstanding (2024, £2,500) 40 30
William Rhodes Chairman's fees, £Nil outstanding (2024, £3,929) 46 46

Compensation of key management personnel of the Group

Key management are those persons having authority and responsibility for planning, controlling and directing the activities of the Company. In the opinion of the Board, the Company's key management are the Directors of GENinCode plc.

Amounts included in the Financial Statements, in aggregate, by category of related party are as follows:

Group Group
31 December 2025 31 December 2024
Directors £'000 £'000
Directors' remuneration (short term benefits) 844 603
Directors' remuneration (pension cost) 19 11
Directors' remuneration (employers NI) 99 56
Share based payments 404 170
Total 1,366 840

Related parties who hold beneficial interests in the Company can be found on page 29 within the Remuneration Committee Report.

28.              Events after the reporting date

The Company has reviewed and evaluated all events and material transactions that have occurred after 31 December 2025 to the date of signing of the financial statements and conclude that there are no material subsequent events which justify adjustment or disclosure, other than disclosed below.

On 9 February 2026 the Company issued 466,159,095 shares at a price of 1.0 pence per share as a result of a fund raising of £4.7m in capital for the Group. A total of 23,000,000 shares were issued to the Directors of the Group under the same terms.

On 7 May 2026, the Company announced that it had approved and granted New Options over an aggregate of 83,847,292 new ordinary shares of 1 pence each in the Company to certain directors and employees of the Company, representing 11.13 per cent. of the Company's existing share capital. Of these New Options, 71,844,958 were granted to directors. The New Options have an exercise price of 1 pence per share and are exercisable on the second anniversary of the date of grant. The new options will vest over a 24-month period and have a 10-year term. Additionally, also on 7 May 2026, 29,856,434 of the options previously granted were surrendered for nil consideration. Following the grant of the New Options and the options surrender, there are options over a total of 85,923,543 ordinary shares in the Company as at the date of this announcement, representing approximately 11.41% of the Company's issued share capital.

There are no significant adjusting events after the reporting date.

29.              Ultimate controlling party

The Group does not have an ultimate controlling party.

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