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FENNEC PHARMACEUTICALS INC. Director's Dealing 2007

May 2, 2007

35599_dirs_2007-05-02_5b173ec1-e948-4b62-b4fa-2d608fdb3895.zip

Director's Dealing

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SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: ADHEREX TECHNOLOGIES INC (AMEX:ADH)
CIK: 0001211583
Period of Report: 2007-04-30

Reporting Person: NORRIS ROBIN J (Director, President & COO)

Derivative Transactions

Date Security Exercise Price Code Shares A/D Expiration Underlying Ownership
2007-04-30 Stock Options (Right to buy) $0.63 A 1000000 Acquired 2014-04-30 Common Stock (1000000) Direct

Holdings (Non-Derivative)

Security Shares Ownership
Common Stock 8100 Direct

Holdings (Derivative)

Security Exercise Price Expiration Underlying Shares Ownership
Stock Options (Right to buy) $0.28 2014-02-28 Common Stock (75000) 75000 Direct
Stock Options (Right to buy) $0.88 2012-12-14 Common Stock (45000) 45000 Direct
Stock Options (Right to buy) $1.2 2012-09-21 Common Stock (15000) 15000 Direct
Stock Options (Right to buy) $1.65 2008-12-12 Common Stock (120000) 120000 Direct
Stock Options (Right to buy) $1.7 2010-05-03 Common Stock (40000) 40000 Direct
Stock Options (Right to buy) $2.25 2010-12-30 Common Stock (75600) 75600 Direct
Stock Options (Right to buy) $2.9 2011-05-21 Common Stock (36400) 36400 Direct

Footnotes

F1: The options to which this note relates are subject to vesting in three (3) installments with one-third vesting immediately and the remaining shares vesting on the first and second anniversary of the Grant Date reported above.