FENNEC PHARMACEUTICALS INC. — Director's Dealing 2007

Dec 5, 2007

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: ADHEREX TECHNOLOGIES INC (AMEX:ADH)
CIK: 0001211583
Period of Report: 2007-12-03

Reporting Person: NORRIS ROBIN J (Director, President & COO)

Derivative Transactions

Date	Security	Exercise Price	Code	Shares	A/D	Expiration	Underlying	Ownership
2007-12-03	Stock Options (Right to buy)	$0.28	A	300000	Acquired	2014-12-03	Common Stock (300000)	Direct

Holdings (Non-Derivative)

Security	Shares	Ownership
Common Stock	8100	Direct

Holdings (Derivative)

Security	Exercise Price	Expiration	Underlying	Shares	Ownership
Stock Options (Right to buy)	$0.28	2014-02-28	Common Stock (75000)	75000	Direct
Stock Options (Right to buy)	$0.63	2014-04-30	Common Stock (1000000)	1000000	Direct
Stock Options (Right to buy)	$0.88	2012-12-14	Common Stock (45000)	45000	Direct
Stock Options (Right to buy)	$1.2	2012-09-21	Common Stock (15000)	15000	Direct
Stock Options (Right to buy)	$1.65	2008-12-12	Common Stock (120000)	120000	Direct
Stock Options (Right to buy)	$1.7	2010-05-03	Common Stock (40000)	40000	Direct
Stock Options (Right to buy)	$2.25	2010-12-30	Common Stock (75600)	75600	Direct
Stock Options (Right to buy)	$2.9	2011-05-21	Common Stock (36400)	36400	Direct

Footnotes

F1: The options to which this note relates vest in three (3) equal installments beginning on the date reported above.