EXELIXIS, INC. — Director's Dealing 2025

Mar 1, 2025

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: EXELIXIS, INC. (EXEL)
CIK: 0000939767
Period of Report: 2025-02-28

Reporting Person: WYSZOMIERSKI JACK L (Director)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2025-02-28	Common Stock	M	15874	$20.50	Acquired	365373	Direct
2025-02-28	Common Stock	S	8768	$37.80	Disposed	356605	Direct

Derivative Transactions

Date	Security	Exercise Price	Code	Shares	A/D	Expiration	Underlying	Ownership
2025-02-28	Option (right to buy)	$20.50	M	15874	Disposed	2025-05-23	Common Stock (15874)	Direct

Footnotes

F1: Includes 18,838 shares of Exelixis, Inc. common stock ("Common Stock") that will be issued to the Reporting Person upon vesting of restricted stock units ("RSUs"). Each RSU is the economic
equivalent of one share of Common Stock.

F2: The sales reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on November 29, 2024.

F3: The option, representing the right to purchase a total of 15,874 shares of Common Stock, became fully exercisable on May 24, 2018.