EXELIXIS, INC. — Director's Dealing 2025

Nov 25, 2025

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: EXELIXIS, INC. (EXEL)
CIK: 0000939767
Period of Report: 2025-11-21

Reporting Person: Aftab Dana (EVP, Research and Development)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2025-11-21	Common Stock	G	24000	—	Disposed	640778	Direct

Holdings (Non-Derivative)

Security	Shares	Ownership
Common Stock	5835	Indirect

Footnotes

F1: On November 21, 2025, the Reporting Person gifted 24,000 shares of Exelixis Inc. common stock ("Common Stock") to a donor-advised fund.

F2: Includes 431,306 shares of Common Stock that will be issued to the Reporting Person upon vesting of restricted stock units ("RSU") and performance-based restricted stock units ("PSUs"). Each
RSU is the economic equivalent of one share of Common Stock and each PSU represents a contingent right to receive one share of Common Stock.

F3: Represents shares of Common Stock under the Exelixis, Inc. 401(k) Plan, pursuant to a plan statement dated as of November 20, 2025.