EXELIXIS, INC. — Director's Dealing 2010

Aug 25, 2010

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: EXELIXIS INC (EXEL)
CIK: 0000939767
Period of Report: 2010-08-24

Reporting Person: KARBE FRANK (EVP & CFO)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2010-08-24	Common Stock	P	5000	$2.98	Acquired	48610	Direct
2010-08-24	Common Stock	P	5000	$2.9793	Acquired	53610	Direct
2010-08-24	Common Stock	P	6500	$2.9798	Acquired	60110	Direct

Holdings (Non-Derivative)

Security	Shares	Ownership
Common Stock	2833.9272	Indirect

Footnotes

F1: Includes 26,110 shares of common stock acquired pursuant to the Exelixis, Inc. 2000 Employee Stock Purchase Plan.

F2: Represents 2833.9272 shares of Exelixis, Inc. common stock under the Exelixis, Inc. 401(k) Plan, pursuant to a plan statement dated as of August 24, 2010.