EXELIXIS, INC. — Director's Dealing 2010

Dec 10, 2010

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: EXELIXIS INC (EXEL)
CIK: 0000939767
Period of Report: 2010-12-09

Reporting Person: Schwab Gisela (EVP & Chief Medical Officer)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2010-12-09	Common Stock	S	4112	$6.50	Disposed	7322	Direct

Holdings (Non-Derivative)

Security	Shares	Ownership
Common Stock	3274.5476	Indirect

Footnotes

F1: The sales reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 26, 2010.

F2: Shares acquired pursuant to the Exelixis, Inc. 2000 Employee Stock Purchase Plan.

F3: Includes 7,322 shares of common stock acquired pursuant to the Exelixis, Inc. 2000 Employee Stock Purchase Plan.

F4: Represents 3,274 shares of Exelixis, Inc. common stock under the Exelixis, Inc. 401(k) Plan, pursuant to a plan statement dated December 9, 2010.