Foreign Filer Report • Sep 30, 2025
Foreign Filer Report
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UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549
For the month of September 2025
Commission File Number: 001-36187
(Translation of Registrant's Name into English)
13 Gad Feinstein Street Park Rehovot, Rehovot 7638517, Israel (Address of principal executive offices)
Indicate by check mark whether the registrant files or will file annual reports under cover of Form 20-F or Form 40-F.
Form 20-F ☒ Form 40-F ☐
This Report of Foreign Private Issuer on Form 6-K, or Form 6-K, is being furnished by Evogene Ltd., or Evogene, to the Securities and Exchange Commission, or SEC, for the sole purposes of: (i) furnishing, as Exhibit 99.1 to this Form 6-K, unaudited condensed consolidated financial statements of Evogene as of and for the six-month period ended June 30, 2025; and (ii) furnishing, as Exhibit 99.2 to this Form 6-K, Evogene's Operating and Financial Review and Prospects, which discusses and analyzes Evogene's financial condition and results of operations as of, and for the six-month period ended, June 30, 2025.
The contents of Exhibits 99.1 and 99.2 to this Form 6-K are incorporated by reference in the registration statements on Form F-3 (SEC File No. 333-277565) and Form S-8 (SEC File Nos. 333-193788, 333-201443, 333-203856, 333-259215 and 333-286197) of Evogene, and will be a part thereof from the date on which this Form 6-K is submitted, to the extent not superseded by documents or reports subsequently filed or furnished.
| Exhibit | |
|---|---|
| No. | Description |
| 99.1 | Unaudited Condensed Consolidated Financial Statements for the Six Months Ended June 30, 2025. |
| 99.2 | Operating and Financial Review and Prospects for the six-month period ended June 30, 2025. |
| 101 | Interactive data files pursuant to Rule 405 of Regulation S-T: (i) Consolidated Interim Statements of Financial Position, (ii) Consolidated Interim Statements of Profit or Loss, (iii) Consolidated Interim Statements of Changes in Equity; (iv) Consolidated Interim Statements of Cash Flows, and (v) Notes to Interim Consolidated Financial Statements. |
Pursuant to the requirements of the Securities Exchange Act of 1934, the Registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.
Date: September 30, 2025
EVOGENE LTD. (Registrant)
By: /s/ Yaron Eldad Yaron Eldad Chief Financial Officer
Exhibit 99.1
| Page | |
|---|---|
| Consolidated Interim Statements of Financial Position | F - 2 |
| Consolidated Interim Statements of Profit or Loss | F - 3 |
| Consolidated Interim Statements of Changes in Equity | F - 4 - F - 5 |
| Consolidated Interim Statements of Cash Flows | F - 6- F - 7 |
| Notes to Consolidated Interim Financial Statements | F - 8 - F - 23 |
| June 30, 2025 |
December 31, 2024 |
||||
|---|---|---|---|---|---|
| Note | Unaudited | ||||
| ASSETS | |||||
| CURRENT ASSETS: | |||||
| Cash and cash equivalents | \$ | 8,329 | \$ | 15,301 | |
| Short-term bank deposits | 3,362 | 10 | |||
| Trade receivables | 1,110 | 1,091 | |||
| Other receivables and prepaid expenses | 4 | 680 | 2,064 | ||
| Deferred expenses related to issuance of warrants | 991 | 1,304 | |||
| Assets held for sale | 9 | 12,218 | - | ||
| Inventories | 1,955 | 1,819 | |||
| 28,645 | 21,589 | ||||
| LONG-TERM ASSETS: | |||||
| Long-term deposits and other receivables | 165 | 12 | |||
| Investment in an associate | 15 | 82 | |||
| Deferred expenses related to issuance of warrants | 1,392 | 1,735 | |||
| Right-of-use-assets | 2,350 | 2,447 | |||
| Property, plant and equipment, net | 1,359 | 1,804 | |||
| Intangible assets, net | - | 12,195 | |||
| 5,281 | 18,275 | ||||
| TOTAL ASSETS | \$ | 33,926 | \$ | 39,864 | |
| LIABILITIES AND EQUITY | |||||
| CURRENT LIABILITIES: | |||||
| Trade payables | \$ | 557 | \$ | 1,228 | |
| Employees and payroll accruals | 1,773 | 1,869 | |||
| Lease liabilities | 680 | 589 | |||
| Liabilities in respect of government grants | 5 | 470 | 323 | ||
| Deferred revenues and other advances | - | 360 | |||
| Warrants and pre-funded warrants liability | 1,168 | 2,876 | |||
| Convertible SAFE | 6 | 10,026 | 10,371 | ||
| Other payables | 520 | 1,079 | |||
| 15,194 | 18,695 | ||||
| LONG-TERM LIABILITIES: | |||||
| Lease liabilities | 1,979 | 1,914 | |||
| Liabilities in respect of government grants | 5 | 4,279 | 4,327 | ||
| Deferred revenues and other advances | 99 | 90 | |||
| 6,357 | 6,331 | ||||
| TOTAL LIABILITIES | \$ | 21,551 | \$ | 25,026 | |
| SHAREHOLDERS' EQUITY: | |||||
| Ordinary shares of NIS 0.2 par value: | |||||
| Authorized − 15,000,000 ordinary shares as of June 30, 2025; Issued and outstanding – 8,714,230 shares as of | |||||
| June 30, 2025 and 6,514,589 shares as of December 31, 2024 | 488 | 363 | |||
| Share premium and other capital reserve | 277,083 | 272,257 | |||
| Accumulated deficit | (281,121) | (274,071) | |||
| Deficit attributable to equity holders of the Company | (3,550) | (1,451) | |||
| Non-controlling interests | 15,925 | 16,289 | |||
| TOTAL EQUITY | 12,375 | 14,838 | |||
| TOTAL LIABILITIES AND EQUITY | \$ | 33,926 | \$ | 39,864 |
The accompanying notes are an integral part of the consolidated interim financial statements.
| Six months ended June 30, |
|||||||
|---|---|---|---|---|---|---|---|
| 2025 | 2024 (*) | ||||||
| Note | Unaudited | ||||||
| Revenues | 3 | \$ 3,227 |
\$ 2,294 |
||||
| Cost of revenues | 1,653 | 646 | |||||
| Gross profit | 1,574 | 1,648 | |||||
| Operating expenses (income): | |||||||
| Research and development, net | 4,792 | 6,499 | |||||
| Sales and marketing | 809 | 1,112 | |||||
| General and administrative | 2,262 | 2,917 | |||||
| Other expenses (income) | (191) | 524 | |||||
| Total operating expenses, net | 7,672 | 11,052 | |||||
| Operating loss | (6,098) | (9,404) | |||||
| Financing income | 1,820 | 591 | |||||
| Financing expenses | (1,088) | (218) | |||||
| Financing income, net | 732 | 373 | |||||
| Share of loss from equity accounted investment | (66) | (20) | |||||
| Loss before taxes on income | (5,432) | (9,051) | |||||
| Taxes on income | 1 | 1 | |||||
| Loss from continuing operations | (5,433) | (9,052) | |||||
| Loss from discontinued operations, net | 9 | (2,238) | (778) | ||||
| Loss | \$ (7,671) |
\$ (9,830) |
|||||
| Attributable to: | |||||||
| Equity holders of the Company | \$ (7,050) |
\$ (9,282) |
|||||
| Non-controlling interests | (621) | (548) | |||||
| \$ (7,671) |
\$ (9,830) |
||||||
| Basic and diluted loss per share from continuing operations, attributable to equity holders of the | |||||||
| Company | \$ (0.77) |
\$ (1.69) |
|||||
| Basic and diluted loss per share from discontinued operations, attributable to equity holders of the Company |
\$ (0.24) |
\$ (0.13) |
|||||
| Weighted average number of ordinary shares used in computing basic and diluted loss per share | 7,012,031 | 5,087,029 |
(*) Reclassified to conform to the current period presentation, following the classification of certain operations as discontinued operations.
The accompanying notes are an integral part of the consolidated interim financial statements.
| Attributable to equity holders of the Company | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Share capital |
Share premium and other capital reserves |
Accumulated deficit Unaudited |
Total | Non controlling interests |
Total equity | ||||||
| Balance as of January 1, 2025 | \$ | 363 | \$ 272,257 |
\$ | (274,071) | \$ | (1,451) | \$ | 16,289 | \$ | 14,838 |
| Loss | - | - | (7,050) | (7,050) | (621) | (7,671) | |||||
| Issuance of ordinary shares, net of issuance expenses |
110 | 4,173 | - | 4,283 | - | 4,283 | |||||
| Exercise of pre-funded warrants | 15 | 374 | - | 389 | - | 389 | |||||
| Exercise of subsidiary options | - | 75 | - | 75 | (75) | - | |||||
| Restricted share units ("RSUs") vested | *) | *) | - | *) | - | *) | |||||
| Share-based compensation and RSUs | - | 204 | - | 204 | 332 | 536 | |||||
| Balance as of June 30, 2025 | \$ | 488 | \$ 277,083 |
\$ | (281,121) | \$ | (3,550) | \$ | 15,925 | \$ | 12,375 |
*) Represents an amount lower than \$1.
The accompanying notes are an integral part of the consolidated interim financial statements.
| Attributable to equity holders of the Company | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Share premium and Share other capital capital reserves |
Accumulated deficit Total Unaudited |
Non controlling interests |
Total equity | |||||||||
| Balance as of January 1, 2024 | \$ | 286 | \$ | 269,353 | \$ | (257,586) | \$ | 12,053 | \$ | 16,632 | \$ | 28,685 |
| Loss | - | - | (9,282) | (9,282) | (548) | (9,830) | ||||||
| Issuance of ordinary shares, net of issuance expenses |
1 | 85 | - | 86 | - | 86 | ||||||
| Forfeiture of non-controlling interests regarding share-based compensation |
- | 22 | - | 22 | (22) | - | ||||||
| RSUs vested | *) | *) | - | *) | - | *) | ||||||
| Share-based compensation and RSUs | - | 188 | - | 188 | 811 | 999 | ||||||
| Balance as of June 30, 2024 | \$ | 287 | \$ | 269,648 | \$ | (266,868) | \$ | 3,067 | \$ | 16,873 | \$ | 19,940 |
*) Represents an amount lower than \$1.
The accompanying notes are an integral part of the consolidated interim financial statements.
| Six months ended June 30, |
||
|---|---|---|
| 2025 | 2024 (*) | |
| Unaudited | ||
| Cash flows from operating activities | ||
| Loss from continuing operations | \$ (5,433) |
\$ (9,052) |
| Adjustments to reconcile loss to net cash used in operating activities: | ||
| Adjustments to the profit or loss items: | ||
| Depreciation and amortization of property, plant and equipment and right-of-use-assets | 600 | 731 |
| Share-based compensation | 472 | 617 |
| Remeasurement of Convertible SAFE | (345) | 24 |
| Net financing expenses (income) | 156 | (364) |
| Loss (gain) from sale of property, plant and equipment | (194) | 524 |
| Amortization of deferred expenses related to issuance of warrants | 656 | - |
| Remeasurement of pre-funded warrants and warrants | (1,318) | - |
| Share of loss of an associate | 67 | 20 |
| Taxes on income | 1 | 1 |
| 95 | 1,553 | |
| Changes in asset and liability items: | ||
| Decrease (increase) in trade receivables | (63) | 119 |
| Decrease (increase) in other receivables and prepaid expenses | 1,369 | (627) |
| Increase in inventories | (601) | (228) |
| Decrease in trade payables | (369) | (716) |
| Decrease in employees and payroll accruals | (124) | (120) |
| Decrease in other payables | (458) | (94) |
| Decrease in deferred revenues and other advances | (351) | (105) |
| (597) | (1,771) | |
| Cash received (paid) during the period for: | ||
| Interest received | 176 | 402 |
| Interest paid | (98) | (41) |
| Taxes paid | (11) | - |
| Net cash used in continuing operating activities | (5,868) | (8,909) |
| Net cash used in operating activities of discontinued operations | (1,615) | (656) |
| Net cash used in operating activities | \$ (7,483) |
\$ (9,565) |
The accompanying notes are an integral part of the consolidated financial statements.
| Six months ended June 30, |
|||
|---|---|---|---|
| 2025 | 2024 (*) | ||
| Unaudited | |||
| Cash flows from investing activities: | |||
| Purchase of property, plant and equipment | \$ (123) |
\$ (166) |
|
| Proceeds from sale of property, plant and equipment | - | 10 | |
| Proceeds from finance sub-lease asset | 17 | - | |
| Withdrawal from (investment in) bank deposits, net | (3,328) | 1,024 | |
| Net cash provided by (used in) continuing investing activities | (3,434) | 868 | |
| Net cash used in investing activities of discontinued operations | - | (2,020) | |
| Net cash used in investing activities | \$ (3,434) |
\$ (1,152) |
|
| Cash flows from financing activities: | |||
| Proceeds from issuance of ordinary shares, net of issuance expenses | \$ 4,283 |
\$ 86 |
|
| Repayment of lease liability | (283) | (470) | |
| Repayment of government grants | (122) | (142) | |
| Net cash provided by (used in) continuing financing activities | 3,878 | (526) | |
| Net cash provided by financing activities of discontinued operations | 112 | 8 | |
| Net cash provided by (used in) financing activities | \$ 3,990 |
\$ (518) |
|
| Exchange rate differences - cash and cash equivalent balances | 25 | (53) | |
| Decrease in cash and cash equivalents | (6,902) | (11,288) | |
| Cash and cash equivalents, beginning of the period | 15,301 | 20,772 | |
| Cash and cash equivalents presented in assets held for sale | (70) | - | |
| Cash and cash equivalents, end of the period | \$ 8,329 |
\$ 9,484 |
|
| Significant non-cash activities | |||
| Purchase of property, plant and equipment, net | \$ 11 |
\$ 15 |
|
| Investment in affiliated Company with corresponding deferred revenues | \$ - |
\$ 120 |
|
| Exercise of pre-funded warrants | \$ 389 |
\$ - |
|
| Right-of-use asset recognized with corresponding lease liability | \$ 207 |
\$ 184 |
|
| Derecognition of right-of-use asset under a finance lease | \$ 13 |
\$ - |
(*) Reclassified to conform to the current period presentation, following the classification of certain operations as discontinued operations.
The accompanying notes are an integral part of the consolidated financial statements.
a. Evogene Ltd. ("Evogene" and together with its subsidiaries, the "Company") was founded on October 10, 1999, as Agro Leads Ltd., a division of Compugen Ltd. In 2002, the Company was spun-off as an independent corporation under the laws of the State of Israel, and changed its name to Evogene Ltd.
The Company's ordinary shares have been listed for trading on the Tel Aviv Stock Exchange since 2007, on the New York Stock Exchange from November 2013 until December 2016, and on the Nasdaq Stock Market since December 2016.
Evogene is a leading computational biology and chemistry company aiming to revolutionize the development of life-science based products by utilizing cutting edge technologies to increase probability of success while reducing development time and cost. The main challenge in product development in the life science industry is finding the winning candidates out of a vast number of possible prospects that address a complex myriad of criteria to reach successful products. The Company believes that by utilizing an advanced computational biology and chemistry platform to identify the most promising candidates addressing multiple development challenges toward successful life-science products, the Company can increase the probability of success while reducing time and cost.
To achieve this mission, the Company has established three unique technological engines – MicroBoost AI, ChemPass AI and GeneRator AI – leveraging Big Data and Artificial Intelligence and incorporating deep multidisciplinary understanding in life sciences. Each technological engine is focused on the discovery and development of products based on one of the following core components: microbes (MicroBoost AI), small molecules (ChemPass AI), and genetic elements (GeneRator AI). The Company uses its technological engines to develop products through subsidiaries and with strategic partners.
As detailed in the Company's audited consolidated financial statements and accompanying notes for the year ended December 31, 2024, the Company had previously approved a plan to implement cost reduction measures, including cuts in non-essential expenses and headcount and deferral of certain research and development programs, in order to reduce spending on programs and headcount, and thereby address the Company's liquidity needs over the twelve-month period from the date on which the consolidated financial statements for 2024 were issued. During the first half of 2025, the Company significantly improved its liquidity position primarily through two key transactions: On April 17, 2025, the Company's board of directors approved an Asset Purchase Agreement with ICL, involving the sale of certain assets, including Lavie Bio Ltd.'s technology platform, development programs, patents, data assets, and Evogene's MicroBoost AI for agriculture operations. On July 8, 2025, the Company announced the closing of this transaction, for total consideration of approximately \$18,714. As part of the transaction Lavie Bio Ltd. redeemed the SAFE which was made by an ICL affiliate at the amount of \$10,000. (see Notes 9 and 10(a)). In addition, during June 2025, the Company raised gross proceeds of approximately \$4,415 by issuing ordinary shares under its At-The-Market (ATM) Sales Agreement (see Note 1(j)). As a result of these events, management determined that it was no longer necessary to implement the previously mentioned planned cost reduction measures. The Company continues to monitor its financial position closely and remains committed to maintaining sufficient liquidity to meet its obligations.
The Company intends to continue to finance its operating activities by raising capital, seeking collaborations with multinational companies in the industry, and from revenues from selling castor seeds.
The Company's management and board of directors are of the opinion that the Company's current and expected financial resources will be sufficient to continue the development of the Company's products for the foreseeable future.
Casterra Ag Ltd. was incorporated on December 29, 2011 and is currently focusing on the development and sales of improved castor seeds and grains for industrial uses. On March 13, 2025, Casterra Ag Ltd. incorporated a Kenyan wholly own subsidiary, Casterra Kenya Limited, which is expected to conduct a production, sales and marketing activities in Kenya.
Evogene Inc. was incorporated in Delaware, United States on September 22, 2006. From 2015 to 2019, Evogene Inc. was engaged in research and development in the field of insect control and located in the Bio-Research and Development Growth (BRDG) Park, in St. Louis, Missouri, United States.
Biomica Ltd. ("Biomica") was incorporated on March 2, 2017, with the mission of discovering and developing human microbiome-based therapeutics.
AgPlenus Ltd. was incorporated on June 10, 2018, with the mission to design effective and sustainable crop protection ag-chemicals products by leveraging predictive biology. On August 27, 2020, AgPlenus Ltd. incorporated a wholly owned U.S. subsidiary, AgPlenus Inc.
Lavie Bio Ltd. was incorporated on January 21, 2019, with the mission to improve food quality and sustainability through the introduction of microbiome-based ag-biological products. In 2019, Lavie Bio Ltd. incorporated two wholly owned subsidiaries, Lavie Bio Inc., located in the City Foundry STL Project, in St. Louis, Missouri, United States, and Lavie Tech Inc. Lavie Tech Inc. wholly owns as a subsidiary Taxon Biosciences, Inc. (see Note 9).

Canonic Ltd. was incorporated on March 25, 2019, with the mission to develop next-generation medical cannabis products. During 2024, Canonic Ltd. ceased its activities.
In August 2022, an affiliate company of ICL and Lavie Bio Ltd. entered a multi-year collaboration agreement for developing novel biostimulant products to enrich fertilizer efficiency. As part of the collaboration, ICL invested through an affiliate company in Lavie Bio Ltd. \$10,000 under a SAFE agreement (simple agreement for future equity)
On April 21, 2025, the Company announced the acquisition of most of the activities of Lavie Bio Ltd., by Dead Sea Works Ltd., an affiliate of ICL Group Ltd., ("ICL") for a total consideration of \$15,250. In addition, ICL will acquire Evogene's MicroBoost AI Tech-Engine for the agriculture field for total consideration of \$3,464. As part of the transaction Lavie Bio Ltd. will redeem the SAFE which was made by an ICL affiliate. On July 8, 2025 the Company announced the closing of this transaction. (see also Note 9 and Note 10).
On December 21, 2022, Biomica, signed a definitive agreement for a \$20,000 financing round, led by Shanghai Healthcare Capital ("SHC"), out of which \$10,000 was invested by the Company in Biomica preferred shares. In addition, certain convertible loans in total amount of \$10,000 were converted by the Company into Biomica's ordinary shares. Following the closing of the transaction on April 25, 2023, the Company was diluted to approximately 67% of the share capital of Biomica, on a fully diluted basis, while SHC is holding approximately 20%, on a fully diluted basis.
a. Basis of preparation of the interim consolidated financial statements:
The interim consolidated financial statements for the six months ended June 30, 2025 have been prepared in accordance with International Accounting Standard 34, "Interim Financial Reporting."
The accompanying unaudited interim consolidated financial statements should be read in conjunction with the audited consolidated financial statements and accompanying notes for the year ended December 31, 2024, included in the Company's Annual Report on Form 20-F filed with the Securities and Exchange Commission (the "SEC") on March 27, 2025.
The accompanying consolidated balance sheet as of June 30, 2025, the consolidated statements of profit or loss, the consolidated statement of changes in shareholders' equity and the consolidated statements of cash flows for the six months ended June 30, 2025 and 2024 are unaudited. These unaudited interim consolidated financial statements have been prepared in accordance with International Financial Reporting Standards ("IFRS") as issued by the International Accounting Standards Board ("IASB") and applicable rules and regulations of the SEC regarding interim financial reporting. In management's opinion, the unaudited interim consolidated financial statements include all adjustments of a normal recurring nature necessary for the fair presentation of the Company's financial position as of June 30, 2025 and December 31, 2024, as well as its results of operations and cash flows for the six months ended June 30, 2025 and 2024. The results of operations for the six months ended June 30, 2025 are not necessarily indicative of the results that may be expected for the year ending December 31, 2025.
The significant accounting policies applied in the preparation of the interim consolidated financial statements are consistent with those followed in the preparation of the 2024 annual consolidated financial statements.
b. Assets or disposal group held for sale and discontinued operations:
Assets or a disposal group are classified as held for sale if their carrying amount will be recovered principally through a sale transaction rather than through continuing use. For this to be the case, the assets must be available for immediate sale in their present condition, the Company must be committed to a sale plan, there must be a program to locate a buyer and it is highly probable that a sale will be completed within one year from the date of classification. Before these assets are classified as available for sale, they are measured in accordance with the Company's accounting policy. After classification as held for sale, these assets are measured at the lower of their carrying amount and fair value less costs to sell and presented separately in the statement of financial position.
The Company recognizes an impairment loss in respect of an asset or group of assets in accordance with IAS 36 - Impairment of Assets. An impairment loss and subsequent remeasurement gains or losses are recorded in profit or loss. Gains are recognized up to the cumulative amount of the previously recognized impairment loss. No impairment loss was recognized during the six month periods ended June 30, 2025 and 2024.
A discontinued operation is a component of the Company that represents a separate major line of business operation or geographical area of operations that either has been disposed of or is classified as a discontinued operation.
As of June 30, 2025 a total amount of \$12,218 was presented as assets held for sale in the consolidated interim statements of financial position.
Loss from discontinued operations, net for the periods ended June 30, 2025 and June 30, 2024 was \$2,238 and \$778, respectively.
The following table disaggregates Company's revenues by timing of revenue recognition:
| Six months ended June 30, |
|||
|---|---|---|---|
| 2025 | 2024 (*) | ||
| Unaudited | |||
| \$ 2,166 |
\$ | 1,273 | |
| 1,061 | 1,021 | ||
| 2,294 | |||
| \$ | 3,227 | \$ |
(*) Reclassified to conform to the current period presentation, following the classification of certain operations as discontinued operations.
| June 30, 2025 Unaudited |
December 31, 2024 |
|||
|---|---|---|---|---|
| Government authorities | \$ | 184 | \$ | 342 |
| Grant receivables | 24 | - | ||
| Prepaid expenses | 260 | 308 | ||
| Supplier's advances | 80 | 1,360 | ||
| Other | 132 | 54 | ||
| \$ | 680 | \$ | 2,064 |
| June 30, 2025 2024 |
December 31, | ||
|---|---|---|---|
| Unaudited | |||
| Balance at January 1, | \$ 4,650 |
\$ | 4,814 |
| Grants received | 106 | 177 | |
| Royalties paid | (122) | (298) | |
| Amounts recorded in profit or loss | 115 | (43) | |
| \$ 4,749 |
\$ | 4,650 |
The Company received research and development grants from the Israel Innovation Authority ("IIA") and undertook to pay royalties of 3%-4% of revenues derived from research and development projects that were financed by the IIA, of up to 100% of the grants received (including accrued interest). As of June 30, 2025, the Company had received cumulative grants amounting to \$9,511 (including accrued interest), of which \$4,018 were repaid to date.
The carrying amounts of cash and cash equivalents, short-term bank deposits, trade receivables, other receivables, long term deposits, trade payables and other payables approximate their fair values due to the short-term maturities of such instruments.
The fair value of the liabilities in respect of government grants is measured using a discount rate that reflects the applicable market rate of interest at the date the grants are received, which approximates the fair value at the respective balance sheet date.
The fair value of lease liability is measured using a discount rate that reflects the Incremental Borrowing Rate (IBR) of interest at the date of the contract.
The fair value measurement of the SAFE agreement is based on the weighted average value of various scenarios regarding Lavie Bio Ltd.'s estimated enterprise value and cash amount considerations at the valuation date. The fair value of the ordinary shares of Lavie Bio Ltd. is measured using the income approach, whereby the expected cash flows generated by Lavie Bio Ltd. are discounted to their present value equivalent using a rate of return that reflects its relative risk, as well as the time value of the money, and is considered to be Level 3 fair value hierarchy.
i. Expenses recognized in the financial statements:
The expense recognized in the Company's financial statements for services provided by employees and service-providers is as follows:
| Six months ended June 30, |
||||
|---|---|---|---|---|
| 2025 | 2024 | |||
| Unaudited | ||||
| Share-based compensation - Attributable to equity holders of the Company | \$ | 204 | \$ | 188 |
| Share-based compensation - Attributable to non-controlling interests (*) | 332 | 811 | ||
| \$ | 536 | \$ | 999 |
(*) Share-based compensation expenses related to discontinued operations in the total amount of \$64 and \$382 for the six months period ended June 30, 2025 and 2024, respectively, are included in the Loss from discontinued operations, net in the interim consolidated statements of profit or loss.
Evogene maintains two share option and equity incentive plans: the Evogene Ltd. 2013 Share Option Plan and the Evogene Ltd. 2021 Share Incentive Plan (the "2021 Plan"). All such option and incentive plans provide for the grant of options to purchase the Company's ordinary shares which generally expire 10 years from the grant date.
During the six months ended June 30, 2025 and 2024, the board of directors of Evogene approved to grant to its employees, directors and consultants an aggregate of 213,500 and 13,300 options, respectively. The fair value of the options determined at their grant date using the binomial model was approximately \$174 and \$41, respectively.
The following table summarizes the number of share options, the weighted average exercise price, and changes to the number of outstanding options held by employees, consultants and directors of Evogene under the applicable plans, as of June 30, 2025 and June 30, 2024 and over the course of the periods then ended:
| 2025 | 2024 | |||
|---|---|---|---|---|
| Number of options |
Weighted average exercise prices (\$) |
Number of options |
Weighted average exercise prices (\$) |
|
| Outstanding on January 1, | 594,088 | 18.72 | 397,452 | 28.8 |
| Granted | 213,500 | 1.7 | 13,300 | 7.0 |
| Exercised | - | - | - | - |
| Forfeited/Expired | (71,986) | 45.9 | (2,938) | 121.1 |
| Outstanding on June 30, | 735,602 | 12.3 | 407,814 | 26.5 |
| Exercisable at June 30, | 323,683 | 24.7 | 314,648 | 30.7 |
The fair value of Company share options granted to employees, directors and consultants for the six months ended June 30, 2025 and 2024 was estimated using the binomial model with the following assumptions:
| 2025 | 2024 | ||
|---|---|---|---|
| Dividend yield (%) | - | - | |
| Expected volatility of the share prices (%) | 55 | 54 | |
| Risk-free interest rate (%) | 4.46 | 4.21-4.24 | |
| Suboptimal factor | 1.8-2 | 1.8-2 | |
| Post-vesting forfeiture rate (%) | 5-20 | 5-20 | |
The expected volatility of the share prices reflects the assumption that the historical volatility of the share prices is reasonably indicative of expected future trends.
The 2021 Plan also provides for the grant of restricted shares and RSUs. During the six months ended June 30, 2024, the board of directors of the Company approved to grant to the Company's employees an aggregate of 1,300 RSUs. The fair value of the RSUs granted during the six months ended June 30, 2024, was approximately \$13, determined at their grant date according to Evogene's share price at the time of their grant since the RSUs were granted at a zero exercise price and no dividends were expected to be distributed during their vesting period. No RSUs were granted during the six months ended June 30, 2025.
The following table summarizes the number of RSUs, the weighted average grant date fair value and the changes to the number of outstanding RSUs held by employees, consultants and directors of Evogene under the 2021 Plan as of June 30, 2025 and June 30, 2024 and during the periods then ended:
| 2025 | 2024 | ||||
|---|---|---|---|---|---|
| Number of RSUs |
Weighted average grant date fair value |
Number of RSUs |
Weighted average grant date fair value |
||
| Outstanding on January 1, | 19,806 | 11.87 | 41,420 | 12.4 | |
| Granted | - | - | 1,300 | 9.7 | |
| Vested | (4,991) | 15.7 | (7,127) | 14.8 | |
| Forfeited/Expired | (2,135) | 12.0 | (112) | 7.5 | |
| Outstanding on June 30, | 12,680 | 10.4 | 35,481 | 11.8 |
v. Evogene's subsidiaries maintain share option and incentive plans with similar terms and conditions. During the six months ended June 30, 2025 and 2024, Evogene's subsidiaries approved to grant their employees, directors and consultants 16,500 and 138,500 options, respectively. The fair value of the options determined at their grant date using the binomial model was approximately \$46 and \$974, respectively.
The following table summarizes the number of share options, the weighted average exercise price, and the changes to the number of outstanding options held by employees, consultants and directors of Evogene's subsidiaries under the subsidiary option plans as of June 30, 2025 and June 30, 2024 and during the periods then ended:
| 2025 | 2024 | |||
|---|---|---|---|---|
| Number of options |
Weighted average exercise prices (\$) |
Number of options |
Weighted average exercise prices (\$) |
|
| Outstanding on January 1, | 1,718,194 | 2.06 | 2,531,134 | 1.63 |
| Granted | 16,500 | 1.00 | 138,500 | 1.46 |
| Exercised | - | - | (5,000) | 0.19 |
| Forfeited/Expired | (63,103) | 2.65 | (748,576) | 0.21 |
| Outstanding on June 30, | 1,671,591 | 1.57 | 1,916,058 | 2.17 |
| Exercisable at June 30, | 1,168,344 | 1.88 | 1,037,638 | 2.01 |
The fair value of Company's subsidiaries' share options granted to employees, directors and consultants for the six months ended June 30, 2025 and 2024 was estimated using the binomial model with the following assumptions:
| 2025 | 2024 | ||
|---|---|---|---|
| Dividend yield (%) | - | - | |
| Expected volatility of the share prices (%) | 76 | 79-83 | |
| Risk-free interest rate (%) | 4.29 | 3.84-4.79 | |
| Suboptimal factor | 2.0 | 1.8-2.0 | |
| Post-vesting forfeiture rate (%) | 8-10 | 5-10 |
vi. The total compensation cost related to all of the Company's equity-based awards, recognized during the presented periods was comprised as follows:
| Six months ended June 30, |
|||
|---|---|---|---|
| 2025 (*) | 2024 (*) | ||
| Unaudited | |||
| Cost of revenues | \$ 22 |
\$ 15 |
|
| Research and development, net | 155 | 213 | |
| Sales and marketing | 71 | 129 | |
| General and administrative | 224 | 260 | |
| \$ 472 |
\$ 617 |
(*) Compensation cost related to discontinued operations in the total amount of \$64 and \$382 for the six month periods ended June 30, 2025 and 2024, respectively, is included in the loss from discontinued operations, net in the consolidated interim statements for profit or loss.

a. General:
The Company operates in three segments, Agriculture, Industry and Human. The Agriculture segment consists of the parent company, Evogene, Evogene's subsidiary AgPlenus Ltd. and the continued operation of Lavie Bio Ltd. The Human segment consists of Evogene's subsidiaries, Biomica Ltd. and Canonic Ltd. The Industry segment consists of Evogene's subsidiary Casterra Ag Ltd. The discontinued operations of Evogene's subsidiary Lavie Bio Ltd. is presented under the line "Loss from discontinued operations, net" in the consolidated interim statement of profit or loss.
The segments were determined on the basis of information considered by the Chief Operating Decision-Maker ("CODM") for purposes of decision-making on the allocation of resources and evaluation of performance. The following Company's segments are engaged in business activities for which they earn revenues and incur expenses, their results are reviewed by the CODM and discrete financial information is available:
| Agriculture segment - | Develops seed traits, ag-chemical products, and ag-biological products to improve plant performance. |
|---|---|
| Industry segment | Develops improved castor bean seeds and grains to serve as a feedstock source for |
| - | other industrial uses. |
| Human segment | Discovery and development of human microbiome-based therapeutics and |
| - | cannabis activity. |
| Unallocated | Other corporate expenses and general development of enabling technologies for |
| - | optimization. |
Each segment's performance is determined based on operating loss reported in the financial statements. The results of a segment reported to the CODM include items attributed directly to a segment, as well as other items, which are indirectly attributed using reasonable assumptions.
b. The following table presents the Company's revenues and operating loss by segments:
| Agriculture | Industry | Human | Unallocated | Total | ||||
|---|---|---|---|---|---|---|---|---|
| Unaudited | ||||||||
| For the six months ended June 30, 2025 | ||||||||
| Revenues | \$ 901 |
\$ | 2,166 | \$ | - | \$ | 160 | \$ 3,227 |
| Operating loss | \$ (2,378) \$ |
(280) \$ | (1,972) \$ | (1,468) \$ | (6,098) | |||
| Net financing income | \$ 732 |
|||||||
| Share of loss from equity accounted investment | \$ (66) |
|||||||
| Loss before taxes on income | \$ (5,432) |
c. The following table presents the Company's revenues and operating loss by segments:
| Agriculture Industry |
Human Unaudited |
Unallocated | Total | |||
|---|---|---|---|---|---|---|
| For the six months ended June 30, 2024 (*) | ||||||
| Revenues | \$ 1,838 |
\$ 196 |
\$ 77 |
\$ 183 |
\$ 2,294 |
|
| Operating loss | \$ (2,513) \$ |
(1,225) \$ | (4,000) \$ | (1,666) \$ | (9,404) | |
| Net financing income | \$ 373 |
|||||
| Share of loss from equity accounted investment | \$ (20) |
|||||
| Loss before taxes on income | \$ (9,051) |
(*) Reclassified to conform to the current period presentation, following the classification of certain operations as discontinued operations.
Detailed below are revenues from major customers each of which accounts for 10% or more, of total revenues. The revenues from major customers detailed below were recorded in the Agriculture segment:
| Six months ended June 30, |
||||
|---|---|---|---|---|
| 2025 | 2024 (*) | |||
| Unaudited | ||||
| Customer A (shareholder of a subsidiary) | 11% | 17% | ||
| Customer B | 63% | - | ||
| Customer C | 14% | 58% |
(*) Reclassified to conform to the current period presentation, following the classification of certain operations as discontinued operations.
During the six months ended June 30, 2025, the Company did not enter into any collaboration agreements which amount to 10% or more of its total revenues for the period ended June 30, 2025. During the second half of 2023 and during the six months ended June 30, 2024, the Company entered into several collaboration agreements which amount to 10% or more of its total revenues for the six months ended June 30, 2024 and June 30, 2025:
During the six month period ended June 30, 2025, Lavie Bio Ltd. recognized \$350 in revenue related to the Amendment and Exclusive Rights Letter.
| Six months ended June 30, |
||
|---|---|---|
| 2025 | 2024(*) | |
| Unaudited | ||
| United States | 11% | 19% |
| Europe | 18% | 61% |
| Israel | 8% | 14% |
| Africa | 63% | 6% |
| 100% | 100% |
(*) Reclassified to conform to the current period presentation, following the classification of certain operations as discontinued operations.
ii. The carrying amounts of non-current assets (property, plant and equipment property and intangible assets) in Evogene's country of domicile (Israel) and in the United States based on the location of the assets, are as follows:
| June 30, 2025 Unaudited |
December 31, 2024 Audited |
|
|---|---|---|
| United States | - | 74% |
| Israel | 100% | 26% |
| 100% | 100% |

Prior to the classification of certain assets of Lavie Bio Ltd's as assets held for sale, the recoverable amount of certain assets was estimated and no impairment loss was identified. As of June 30, 2025, no other impairment losses were recorded in respect of the assets held for sale.
As of June 30, 2025, the following assets were classified as held for sale:
| June 30, 2025 |
|
|---|---|
| Assets classified as held for sale: | |
| Cash and cash equivalents | 70 |
| Inventories | 325 |
| Property, plant and equipment, net | 110 |
| Intangible assets | 11,713 |
| Assets held for sale | 12,218 |
| Liabilities classified as held for sale: | |
| Liabilities attributed to assets held for sale | - |
| Net assets held for sale | 12,218 |
The following data represents the operating results attributed to the discontinued operation:
| June 30, | |
|---|---|
| 2025 | 2024 |
| 143 | 2,810 |
| 123 | 201 |
| 2,609 | |
| 2,244 | 3,369 |
| (760) | |
| (14) | (18) |
| (778) | |
| - | - |
| (2,238) | (778) |
| (2,238) | (778) |
| (1,650) | (645) |
| (588) | (133) |
| (2,238) | (778) |
| 20 (2,224) (2,238) |
The following discussion and analysis provide information that we believe to be relevant to an assessment and understanding of our results of operations, financial condition and prospects for the periods described and as of the date of this Operating and Financial Review and Prospects. This discussion should be read in conjunction with our consolidated interim financial statements and the notes to the financial statements, which are included as Exhibit 99.1 to the Report of Foreign Private Issuer on Form 6-K to which this Operating and Financial Review and Prospects is attached. In addition, this information should also be read in conjunction with the information contained in our Annual Report on Form 20-F for the year ended December 31, 2024, filed with the Securities and Exchange Commission, or SEC, on March 27, 2025, or the 2024 Annual Report, including the consolidated annual financial statements as of, and for the year ended, December 31, 2024, and the accompanying notes included therein, including the information under "Item 5. Operating and Financial Review and Prospects" in the 2024 Annual Report.
This Operating and Financial Review and Prospects contains historical information and forward-looking statements within the meaning of The Private Securities Litigation Reform Act of 1995 with respect to the business, financial condition and results of operations of Evogene. Forward-looking statements can be identified based on our use of forward-looking words such as "believe," "expect," "expected," "intend," "plan," "may," "should," "anticipate," "could," "might," "seek," "target," "will," "project," "forecast," "continue" or their negatives or variations of these words or other comparable words, or by the fact that these statements do not relate strictly to historical matters. Forward-looking statements relate to anticipated or expected events, activities, trends or results as of the date they are made. Because forward-looking statements relate to matters that have not yet occurred, these statements are inherently subject to risks and uncertainties that could cause our actual results to differ materially from any future results expressed or implied by the forward-looking statements. Many factors could cause our actual activities or results to differ materially from the activities and results anticipated in forward-looking statements.
We believe that our forward-looking statements are reasonable; however, these statements are only current predictions and are subject to known and unknown risks, uncertainties and other factors that may cause our or our industry's actual results, levels of activity, performance or achievements to be materially different from those anticipated by the forward-looking statements. We describe and/or refer to many of these risks in greater detail in Item 3.D under the heading "Risk Factors" in our 2024 Annual Report.
All forward-looking statements contained in this Operating and Financial Review and Prospects speak only as of the date of this document and are expressly qualified in their entirety as described herein and by the cautionary statements contained within the "Risk Factors" section of the 2024 Annual Report. We do not undertake to update or revise forward-looking statements to reflect events or circumstances that arise after the date on which such statements are made or to reflect the occurrence of unanticipated events, except as required by law. In evaluating forward-looking statements, you should consider these risks and uncertainties and not place undue reliance on our forward-looking statements.
The terms "Evogene," "we," "us," "our," "our company" and "the company" in this Operating and Financial Review and Prospects refer to Evogene Ltd. and its consolidated subsidiaries, consisting of Lavie Bio Ltd., or Lavie Bio, Ag Plenus Ltd., or AgPlenus, Biomica Ltd., or Biomica, Casterra Ag Ltd., or Casterra, Evogene Inc., and their consolidated subsidiaries, unless the context otherwise requires.
Evogene is a leading computational biology and chemistry company aiming to revolutionize the development of life-science based products by utilizing cutting edge technologies to increase probability of success while reducing development time and cost.
The main challenge in product development in the life science industry is finding the winning candidates out of a vast number of possible prospects that address a complex myriad of criteria to reach successful products. We believe that by utilizing an advanced computational biology and chemistry platform to identify the most promising candidates addressing multiple development challenges toward successful life-science products, we can increase the probability of success while reducing time and cost.
To achieve this mission, we have established three unique technological engines – MicroBoost AI, ChemPass AI and GeneRator AI – leveraging Big Data and Artificial Intelligence and incorporating deep multidisciplinary understanding in life sciences. Each technological engine is focused on the discovery and development of products based on one of the following core components: microbes (MicroBoost AI), small molecules (ChemPass AI), and genetic elements (GeneRator AI). Evogene uses its technological engines to develop products through subsidiaries and with strategic partners.
During 2025, Evogene has been focusing on the use of its ChemPass AI tech-engine for the AI-driven discovery and optimization of small molecules in the field of pharmaceuticals and agriculture. As part of our new strategy, we are building a dedicated business development team in pharma. In addition, we are optimizing our agricultural offering around ChemPass AI through the integration of our subsidiary's, AgPlenus, activity into Evogene, as part of which we plan to effect a 40% workforce reduction at AgPlenus and 30% workforce reduction at Evogene. This integration enhances ChemPass AI's application in crop protection, unlocking deeper synergies and operational efficiency.
That streamlining process is part of our overall cost reduction plan, most of which was completed by the end of the second quarter of 2025, the initial impact of which was partially reflected in our 2025 first-half results, and the full effect of which is expected to be realized in the second half of 2025.
The expected upcoming activities for our other subsidiaries are as follows:
On April 21, 2025, we announced, and on July 8, 2025, we completed, the sale of most of the activity of Lavie Bio to Dead Sea Works Ltd., an affiliate of ICL Group Ltd., or ICL, for aggregate consideration of US\$15.25 million. In addition, ICL acquired our MicroBoost AI Tech-Engine for the agriculture field for approximately \$3.5 million. As part of that transaction, Lavie Bio redeemed the SAFE investment that had been made by an ICL affiliate.
On June 5, 2025, we announced that due to the unexpected medical condition of Dr. Elran Haber, Biomica's Chief Executive Officer, Dr. Haber will cease acting as Biomica's chief Executive Officer and Mr. Ofer Haviv, Evogene's President and Chief Executive Officer, has replaced him. As part of a streamlining process, Biomica reduced staff and management overhead and is now focused on completing its clinical trial for BMC128, its immuno-oncology program (by early 2026) and pursuing potential partners to take the lead on its development programs.
On June 10, 2025 we announced the completion of our first-in-class foundation model for generative molecule design, developed in collaboration with Google Cloud. The new model addresses the challenge of identifying novel small molecules that meet multiple product criteria, an essential requirement for pharma and agriculture applications.
On August 12, 2025, we announced a collaboration with Tel Aviv University. We partnered with Professor Ehud Gazit, a world-renowned expert in biomolecular self-assembly, to discover small molecule therapeutics targeting metabolic diseases such as gout and PKU. This marks the beginning of a broader pharma ecosystem, leveraging ChemPass AI for next-generation drug discovery.
After market close on July 24, 2024, we effected a reverse share split of our issued and outstanding ordinary shares, at a ratio of 1-for-10. As a result of the reverse share split, our shareholders were entitled to receive for every ten ordinary shares, par value 0.02 New Israeli Shekels, or NIS, per share, held by them, one ordinary share, par value NIS 0.20. Our ordinary shares began trading on a post-reverse split basis (i) on the Nasdaq Capital Market, at the open of the market on July 25, 2024, and (ii) on the Tel Aviv Stock Exchange, at the open of the market on July 28, 2024, in each case under our existing trading symbol "EVGN".
The reverse share split was approved by our shareholders at our 2024 annual meeting of shareholders held on June 13, 2024, to be effected at our board of directors' discretion within an approved range of ratios.
As a result of the implementation of the reverse share split, our registered share capital under our amended and restated articles of association, which were in effect at that time, which consists of NIS 3,000,000, was adjusted from being divided into 150,000,000 ordinary shares of NIS 0.02 par value each, to being divided into 15,000,000 ordinary shares of NIS 0.20 par value each. The reverse share split adjusted the number of issued and outstanding ordinary shares of our company from 50,796,416 ordinary shares to 5,100,438 ordinary shares at the time at which it was effected, after taking into consideration adjustments based on the treatment of fractional shares in the reverse share split.
The number of ordinary shares available for issuance under our equity incentive plans was adjusted by the same 1-for-10 ratio. In addition, a proportionate decrease to the number of ordinary shares issuable upon exercise, and a corresponding upwards adjustment to the per share exercise price, was made to all outstanding options entitling the holders to purchase ordinary shares. Similarly, a proportionate downwards adjustment was made to the number of ordinary shares issuable upon settlement of our outstanding Restricted Share Units, or RSUs.
All ordinary share amounts and weighted average selling prices on dates, or during periods of time, that preceded the effectiveness of the reverse share split (i.e., on or prior to July 24, 2024) included in this Operating and Financial Review and Prospects (including under "Liquidity and Capital Resources— At The Market (ATM) Offerings" below) have been retroactively adjusted to reflect the 1-for-10 reverse share split.
The financial results for the six-month period ended June 30, 2025 of Lavie Bio and the MicroBoost AI for Ag operations, are presented as a single-line item in Evogene's consolidated statements of profit and loss and in this Operating and Financial Review and Prospects under the caption – "Loss from discontinued operations, net". This accounting treatment follows our announced intention, prior to, and as of, June 30, 2025, to sell the majority of Lavie Bio's activities and the MicroBoost AI for Ag. As a result, all prior period amounts (specifically, for purposes hereof, for the six months ended June 30, 2024) were reclassified to conform to this presentation.
Our total revenues for the six-month period ended June 30, 2025 were approximately \$3.2 million compared to approximately \$2.3 million in the sixmonth period ended June 30, 2024. This increase was primarily driven by higher revenues recognized by Casterra, attributed to seed sales in the first half of 2025, partially offset by a decrease in AgPlenus revenues.

Cost of revenues for the six-month period ended June 30, 2025 was approximately \$1.7 million, an increase compared to approximately \$0.6 million for the six-month period ended June 30, 2024. The increase in cost of revenues is mainly due to the increased revenues in Casterra, as mentioned above.
Gross profit for the six-month period ended June 30, 2025 was approximately \$1.6 million and remained stable compared to approximately \$1.6 million in the six-month period ended June 30, 2024, despite the increase in revenues, reflecting decreased gross margin.
Research and Development Expenses, Net. Research and development expenses, net of non-refundable grants, decreased by approximately \$ 1.7 million, or 26.2%, to approximately \$4.8 million for the six-month period ended June 30, 2025, from approximately \$6.5 million for the six-month period ended June 30, 2024. The decrease was primarily due to reduced expenses in Biomica and the cessation of Canonic Ltd.'s, or Canonic, operations at the beginning of 2024.
Sales and Marketing Expenses. Sales and marketing expenses decreased by approximately \$0.3 million, or 27.3%, to approximately \$0.8 million for the six-month period ended June 30, 2025, from approximately \$1.1 million for the six-month period ended June 30, 2024. The decrease was mainly due to reductions in personnel-related costs for each of Evogene, AgPlenus and Biomica.
General and Administrative Expenses. General and administrative expenses decreased by approximately \$0.6 million, or 20.7%, to approximately \$2.3 million for the six-month period ended June 30, 2025, from approximately \$2.9 million for the six-month period ended June 30, 2024. The decrease was mainly attributable to lower personnel costs of Evogene, a reduction in D&O insurance costs and lower non-cash compensation expenses of Casterra, Biomica, and AgPlenus.
Other Expenses (income). Other income of approximately \$0.2 million was recorded in the first half of 2025 as part of the accounting treatment related to a sub-lease agreement. The decision to cease Canonic's operations in the first half of 2024 resulted in other expenses of approximately \$0.5 million during that period, primarily due to the impairment of fixed assets.
Financing Income. Financing income increased by approximately \$1.2 million, or 200%, to approximately \$1.8 million for the six-month period ended June 30, 2025, compared to approximately \$0.6 million for the six-month period ended June 30, 2024. The increase was mainly attributable to the accounting treatment of the revaluation of pre-funded warrants and warrants issued in our August 2024 registered direct offering, or the August 2024 Offering, and to the remeasurement of a convertible SAFE.
Financing Expenses. Financing expenses increased by approximately \$0.9 million, or 450%, to approximately \$1.1 million for the six-month period ended June 30, 2025, from approximately \$0.2 million for the six-month period ended June 30, 2024. The increase was mainly attributable to the accounting treatment of the amortization of deferred expenses related to issuance of warrants in the August 2024 Offering.
Loss from discontinued operations, net. Loss from discontinued operations, net, increased by approximately \$1.4 million, or 175%, to approximately \$2.2 million for the six-month period ended June 30, 2025, compared to approximately \$0.8 million for the six-month period ended June 30, 2024. The increase was mainly attributable to a decrease in revenues recorded by Lavie Bio for the six-month period ended June 30, 2025, compared to the six-month period ended June 30, 2024.
For the six-month periods ended June 30, 2025 and 2024, we recorded insignificant amounts for taxes on income.
The amount of our overall loss decreased by approximately \$2.1 million, or 21.4%, to approximately \$7.7 million for the six-month period ended June 30, 2025, from approximately \$9.8 million for the six-month period ended June 30, 2024. The decrease in net loss was primarily due to decreased operating expenses and increased financing income, net, partially offset by increased loss from discontinued operations, net.
Our working capital requirements generally reflect the growth in our business and have historically been provided by cash raised from our investors, payments from our collaborators and government grants. As of June 30, 2025, we had cash and cash equivalents and short-term bank deposits of approximately \$11.9 million and working capital of approximately \$13.5 million, which is calculated by subtracting our current liabilities from our current assets. As of June 30, 2025, we had approximately \$4.7 million of outstanding indebtedness related to government grants.
In recent periods, we have raised capital through "at-the-market", or ATM, offerings, as defined in Rule 415(a)(4) promulgated under the Securities Act of 1933, as amended.
On January 14, 2021 and February 19, 2021, we entered into Controlled Equity OfferingSM Sales Agreements, or the January Sales Agreement and February Sales Agreement, respectively, with Cantor Fitzgerald & Co., or the Agent, pursuant to which we offered and sold, from time to time, our ordinary shares, through the Agent in an ATM offering. During January 2024 we raised gross proceeds of approximately \$3 thousand under the January Sales Agreement and/or February Sales Agreement, in the aggregate. In March 2024, we terminated the ATM offering with the Agent.
On March 1, 2024, we filed a shelf registration statement on Form F-3 with the SEC under which we may offer and sell from time to time in one or more offerings, our ordinary shares, rights, warrants and units having an aggregate offering price of up to \$200 million.
On March 28, 2024 we entered into a Sales Agreement, or the March Sales Agreement, with Lake Street Capital Markets, LLC, or Lake Street, pursuant to which we may offer and sell, from time to time, our ordinary shares, through Lake Street in an ATM offering, for an aggregate offering amount of up to \$7.3 million. On August 26, 2024, the maximum aggregate offering amount was reduced to up to \$4.5 million. From April through June 2025, 1,913,650 ordinary shares were issued through the ATM offering under the March Sales Agreement, at an average selling price of \$2.3071 per share, resulting in gross proceeds to us of approximately \$4.4 million. This ATM offering was fully utilized, and effective as of September 4, 2025, the ATM offering with Lake Street was terminated.
On August 23, 2024, we entered into a definitive securities purchase agreement, or the August Securities Purchase Agreement, with an institutional investor, and on August 26, 2024, we completed the transactions under that agreement, pursuant to which we raised an aggregate of \$5.5 million of gross proceeds. Under the August Securities Purchase Agreement, we issued and sold to the investor in a registered direct offering, (i) 265,000 ordinary shares, and (ii) pre-funded warrants to purchase up to 1,427,308 ordinary shares. The pre-funded warrants have an exercise price of \$0.0001 per ordinary share, were immediately exercisable and may be exercised at any time until exercised in full. In a concurrent private placement under the August Securities Purchase Agreement, we also sold to the investor unregistered Series A ordinary warrants to purchase up to 1,692,308 ordinary shares, or the Series A Warrants, and unregistered Series B ordinary warrants to purchase up to 1,692,308 ordinary shares, or the Series B Warrants. Each ordinary share (or pre-funded warrant) was sold with one Series A Warrant to purchase one ordinary share and one Series B Warrant to purchase one ordinary share at a combined purchase price of \$3.25. The Series A Warrants have an exercise price of \$3.55 per share, were immediately exercisable upon issuance and will expire five years from issuance. The Series B Warrants have an exercise price of \$3.55 per share, were immediately exercisable upon issuance and will expire eighteen months from issuance.
We expect that our primary sources of liquidity for the remainder of 2025 will consist of:
We believe that our existing cash as of June 30, 2025, including amounts raised in April through June 2025 pursuant to the March Sales Agreement, will be sufficient to meet our projected cash requirements for at least the next 12 months. Our intention is to focus on creating exit events for some of our subsidiaries in the long term. An exit event is expected to inject funds to further support our activities based on our new strategy. We may not complete any such exit events or, if completed, they may not result in the funds we currently expect. We may also seek additional capital on our parent company level for strategic considerations, even if we believe we have sufficient funds for our current or future operating plans.
Although we have sufficient cash, cash equivalents and short-term bank deposits that we believe will enable us to fund our operations during the next 12-month period at our current level of annual expenditures, our ability to fund our capital needs in the longer term depends on our ongoing ability to generate cash from existing and future collaborations, our revenues, and from our ability to raise additional funds. To the extent that existing cash, cash equivalents and short-term bank deposits are insufficient to fund our future activities, we may need to raise additional funding through debt or equity financing. Additional funds may not be available when we need them on terms that are acceptable to us, or at all.
If adequate funds are not available to us on a timely basis, we may be required to delay, limit, scale back or cease our research and development activities, establishment and maintenance of sales and marketing capabilities or other activities that may be necessary to commercialize our product candidates.
The following table presents the major components of net cash flows used in or provided by (as applicable) operating, investing and financing activities for the periods presented. For a discussion of our net cash flows for the year ended December 31, 2024, please see "Item 5. Operating and Financial Review and Prospects— B. Liquidity and Capital Resources— Cash Flows" in our 2024 Annual Report:
| Six Months Ended June 30, | ||||
|---|---|---|---|---|
| 2025 | 2024 | |||
| (U.S. dollars, in thousands) | ||||
| Net cash used in operating activities | \$ | (7,483) \$ (9,565) |
||
| Net cash used in investing activities | (3,434) (1,152) |
|||
| Net cash provided by (used in) financing activities | 3,990 | (518) | ||
| Exchange rate differences - cash and cash equivalents | 25 | (53) | ||
| Decrease in cash and cash equivalents | \$ | (6,902) \$ (11,288) |

Cash used in operating activities for the six-month period ended June 30, 2025 was approximately \$7.5 million and primarily reflected our loss from continuing operations of approximately \$5.4 million and net cash used in operating activities of discontinued operations of approximately \$1.6 million. The cash used in operating activities was increased by the elimination of certain non-cash items that were taken into account in calculating, and that decreased our overall loss, including financing income of approximately \$1.3 million related to remeasurement of pre-funded warrants and warrants, approximately \$0.6 million of changes in asset and liability items, and financing income of approximately \$0.3 million due to the remeasurement of a convertible SAFE. These upwards adjustments to cash used were partially offset by the elimination of certain non-cash items that were taken into account in calculating, and that increased our overall loss, including approximately \$0.7 million of amortization of deferred expenses related to issuance of warrants, approximately \$0.6 million of depreciation expenses, and approximately \$0.5 million of share-based compensation expenses.
Cash used in operating activities for the six-month period ended June 30, 2024 was approximately \$9.6 million and primarily reflected our loss from continuing operations of approximately \$9.1 million and net cash used in operating activities of discontinued operations of approximately \$0.7 million. The cash used in operating activities was reduced mainly by the elimination of certain non-cash items that were taken into account in calculating, and that increased our overall loss, including approximately \$0.7 million of depreciation expenses, approximately \$0.6 million of share-based compensation expenses and approximately \$0.5 million of loss from the sale of property, plant and equipment. These downwards adjustments to cash used were offset by approximately \$1.8 million of changes in asset and liability items, mainly due to an increase in other receivables and prepaid expenses, increase in inventories and a decrease in trade payables, employees and payroll accrual balances.
Cash used in investing activities was approximately \$3.4 million for the six-month period ended June 30, 2025. This primarily reflects approximately \$3.3 million of cash used for investment in short-term bank deposits, net, and approximately \$0.1 million of cash used for the purchase of property, plant and equipment.
Cash used in investing activities was approximately \$1.2 million for the six-month period ended June 30, 2024. This primarily reflects approximately \$1.0 million of cash used for investment in short-term bank deposits, net, and approximately \$0.2 million of cash used for the purchase of property, plant and equipment.
Cash provided by financing activities was approximately \$4.0 million for the six-month period ended June 30, 2025, which was primarily attributable to approximately \$4.3 million of cash proceeds from the issuance of our ordinary shares, net of issuance expenses, partially offset by approximately \$0.3 million of cash used for the repayment of a lease liability.
Cash used in financing activities was approximately \$0.5 million for the six-month period ended June 30, 2024, which was primarily attributable to approximately \$0.5 million of cash used for the repayment of a lease liability and approximately \$0.1 million of cash used for the repayment of government grants, partially offset by approximately \$0.1 million of cash proceeds from the issuance of our ordinary shares, net of issuance expenses.
During the six months ended June 30, 2025, we received approximately \$0.1 million of additional grants from the Israeli government, while we repaid approximately \$0.1 million in respect of refundable projects. For a discussion of our existing government grants related to our research and development efforts, please see "Item 5. Operating and Financial Review and Prospects— B. Liquidity and Capital Resources— Government Grants" in our 2024 Annual Report.
A significant portion of our expenses is denominated in currencies other than the U.S. dollar. We are therefore subject to non-U.S. currency risks and non-U.S. exchange exposure, especially the NIS. Exchange rates can be volatile and a substantial change in the exchange rate of foreign currencies against the U.S. dollar could increase or reduce our expenses and net loss and impact the comparability of results from period to period. For example, for the six-month period ended June 30, 2025, assuming a 10% devaluation of the U.S. dollar against the NIS, we would have experienced an increase in our net loss of approximately \$0.9 million, while assuming a 10% appreciation of the U.S. dollar against the NIS, we would experience a decrease in our net loss of approximately \$0.9 million.
The actual exchange rate of the U.S. dollar against the NIS shifted over the course of the six-month period ended June 30, 2025 with the U.S. dollar devaluing against the NIS by 7.5% and the actual exchange rate of the U.S. dollar against the NIS shifted over the course of the six-month periods ended June 30, 2024 with the U.S. dollar appreciating against the NIS by 3.6%.
Other than as described immediately above or disclosed elsewhere in our 2024 Annual Report, we are not aware of any trends, uncertainties, demands, commitments or events during our current fiscal year that are reasonably likely to have a material effect on our revenues, income, profitability, liquidity or capital resources, or that would cause the financial information included in our 2024 Annual Report to be not necessarily indicative of our future operating results or financial condition.
The preparation of financial statements requires us to make estimates and assumptions that affect the reported amounts of assets, obligations, income and expenses during the reporting periods. A comprehensive discussion of our critical accounting policies is included in "Item 5. Operating and Financial Review and Prospects" in our 2024 Annual Report.

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