ENTROPY NEURODYNAMICS LIMITED — Director's Dealing 2024

Nov 7, 2024

Appendix 3Z Final Director's Interest Notice

Rule 3.19A.3

Appendix 3Z

Final Director's Interest Notice

Information or documents not available now must be given to ASX as soon as available. Information and documents given to ASX becomes ASX's property and may be made public.

Introduced 30/9/2001.

Name of entity	Tryptamine Therapeutics Limited
ABN	78 163 765 991

We (the entity) give ASX the following information under listing rule 3.19.A.3 and as agent for the director for the purposes of section 205G of the Corporations Act.

Name of director	Clarke Barlow
Date of last notice	03 May 2024
Date that director ceased to be	08 November 2024
director

Part 1 - Director's relevant interests in securities of which the director is the registered holder

In the case of a trust, this includes interests in the trust made available by the responsible entity of the trust Note: In the case of a company, interests which come within paragraph (i) of the definition of "notifiable interest of a director" should be disclosed in this part.

Number & class of securities

508,000 - ORDINARY FULLY PAID SHARES 2,000,000 - UNLISTED DIRECTOR OPT @ $0.0375 EXP 01/12/2027 1,000,000 - UNLISTED DIRECTOR OPT @ $0.05 EXP 01/12/2027 1,000,000 - UNLISTED DIRECTOR OPT @ $0.075 EXP 01/12/2027

Part 2 - Director's relevant interests in securities of which the director is not the registered holder

Note: In the case of a company, interests which come within paragraph (ii) of the definition of "notifiable interest of a director" should be disclosed in this part.

In the case of a trust, this includes interests in the trust made available by the responsible entity of the trust

Name of holder & nature of	Number & class of Securities
interest
Note: Provide details of the circumstances
giving rise to the relevant interest.
Nil	Nil

Part 3 - Director's interests in contracts

Detail of contract	1. Incentive Plan allotment as approved by
	shareholders on 8 November 2024.

• See chapter 19 for defined terms.

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Appendix 3Z Page 1

Appendix 3Z Final Director's Interest Notice

Nature of interest	1. Shareholder approved on 8 November 2024 anIncentive Plan package of 4.5m options, comprising1.0m Tranche 1 options, 1.0m Tranche 2 options and2.5m Tranche 3 options. Following Mr Barlow'sresignation, Mr Barlow will retain only the Tranche 1options, which are yet to be issued, however will beissued within 1 month of the AGM.
Name of registered holder (ifissued securities)	1. Clarke Barlow
No. and class of securities towhich interest relates	1. 1,000,000 - UNLISTED OPTIONS EXERCISABLEAT $0.03 AND EXPIRING 31 DEC 2027.

• See chapter 19 for defined terms.

Appendix 3Z Page 2

11/03/2002