DYADIC INTERNATIONAL INC

Regulatory Filings • Aug 21, 2020

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Dyadic International, Inc.

140 Intracoastal Pointe Drive

Suite 404

Jupiter, Florida 33477

August 21, 2020

Via EDGAR Transmission

Securities and Exchange Commission

Division of Corporation Finance

Mail Stop 3010

100 F Street, N.E.

Washington, D.C. 20549

Attention: Chris Edwards

Re:
Registration Statement on Form S-3 (Registration No. 333-245687)

Ladies and Gentlemen:

In accordance with Rule 461 under the Securities Act of 1933, as amended, we hereby request acceleration of the effective date of the Registration Statement on Form S-3 (Registration No. 333-245687) (the “Registration Statement”) of Dyadic International, Inc. (the “Company”). We respectfully request that the Registration Statement become effective as of 4:00 p.m., Eastern Time, on August 25, 2020, or as soon as practicable thereafter. Once the Registration Statement has been declared effective, please orally confirm that event with our counsel, Cahill Gordon & Reindel LLP, by calling Kimberly C. Petillo-Decossard at (212) 701-3265.

If you have any questions regarding the foregoing, please do not hesitate to contact Kimberly C. Petillo-Decossard of Cahill Gordon & Reindel LLP at (212) 701-3265. Thank you in advance for your consideration.

Very truly yours,

Dyadic International, Inc.

By: /s/ Mark Emalfarb

Name: Mark Emalfarb

Title: Chief Executive Officer

cc: Kimberly C. Petillo-Decossard, Cahill Gordon & Reindel LLP