CYTOKINETICS INC — Director's Dealing 2025

Dec 2, 2025

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: CYTOKINETICS INC (CYTK)
CIK: 0001061983
Period of Report: 2025-12-01

Reporting Person: Kaye Edward M. MD (Director)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2025-12-01	Common Stock	M	8064	$12.40	Acquired	18041	Direct
2025-12-01	Common Stock	M	20000	$14.25	Acquired	38041	Direct
2025-12-01	Common Stock	S	28064	$66.72	Disposed	9977	Direct

Derivative Transactions

Date	Security	Exercise Price	Code	Shares	A/D	Expiration	Underlying	Ownership
2025-12-01	Non-Qualified Stock Option (Right to Buy)	$12.40	M	8064	Disposed	2027-01-03	Common Stock (8064)	Direct
2025-12-01	Non-Qualified Stock Option (Right to Buy)	$14.25	M	20000	Disposed	2027-05-18	Common Stock (20000)	Direct

Footnotes

F1: This option shall vest and become exercisable as to 8,064 shares divided into equal monthly installments such that the option shall be 100% vested on January 3, 2018.

F2: This option shall vest and become exercisable in 12 equal monthly installments and shall become fully vested on May 18, 2018.