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CYTOKINETICS INC Director's Dealing 2025

Dec 5, 2025

30870_dirs_2025-12-05_cfdf27b0-4170-4e8b-ad59-daad7f4bd3f9.zip

Director's Dealing

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SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: CYTOKINETICS INC (CYTK)
CIK: 0001061983
Period of Report: 2025-12-05

Reporting Person: Callos Andrew (EVP, Chief Commercial Officer)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2025-12-05	Common Stock	M	15000	$23.26	Acquired	65660	Direct
2025-12-05	Common Stock	M	11000	$39.13	Acquired	76660	Direct
2025-12-05	Common Stock	M	15858	$37.63	Acquired	92518	Direct
2025-12-05	Common Stock	M	10628	$37.63	Acquired	103146	Direct
2025-12-05	Common Stock	S	52486	$65.95	Disposed	50660	Direct

Derivative Transactions

Date	Security	Exercise Price	Code	Shares	A/D	Expiration	Underlying	Ownership
2025-12-05	Non-Qualified Stock Option (Right to Buy)	$23.26	M	15000	Disposed	2031-03-31	Common Stock (15000)	Direct
2025-12-05	Non-Qualified Stock Option (Right to Buy)	$39.13	M	11000	Disposed	2033-03-06	Common Stock (11000)	Direct
2025-12-05	Non-Qualified Stock Option (Right to Buy)	$37.63	M	15858	Disposed	2032-03-01	Common Stock (15858)	Direct
2025-12-05	Incentive Stock Option (Right to Buy)	$37.63	M	10628	Disposed	2032-03-01	Common Stock (10628)	Direct