CYTOKINETICS INC — Director's Dealing 2025

Dec 23, 2025

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: CYTOKINETICS INC (CYTK)
CIK: 0001061983
Period of Report: 2025-12-22

Reporting Person: Blum Robert I (Director, President & CEO)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2025-12-22	Common Stock	M	54727	$6.67	Acquired	404929	Direct
2025-12-22	Common Stock	F	30426	$68.18	Disposed	374503	Direct
2025-12-22	Common Stock	M	16506	$6.67	Acquired	391009	Direct

Derivative Transactions

Date	Security	Exercise Price	Code	Shares	A/D	Expiration	Underlying	Ownership
2025-12-22	Non-Qualified Stock Option (Right to Buy)	$6.67	M	54727	Disposed	2026-02-23	Common Stock (54727)	Direct
2025-12-22	Incentive Stock Option (Right to Buy)	$6.67	M	16506	Disposed	2026-02-23	Common Stock (16506)	Direct

Holdings (Non-Derivative)

Security	Shares	Ownership
Common Stock	2083	Indirect
Common Stock	2083	Indirect

Footnotes

F1: Net share settlement transaction. Not a market transaction.

F2: Shares represent withholding of shares to cover exercise price and tax withholding obligations resulting from the net share settlement of 54,727 non-qualified stock options.

F3: Cash exercise and hold transaction.

F4: Shares held by The Bridget Blum 2003 Irrevocable Trust.

F5: Shares held by The Brittany Blum 2003 Irrevocable Trust.