CYTOKINETICS INC — Director's Dealing 2010

Apr 1, 2010

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: CYTOKINETICS INC (CYTK)
CIK: 0001061983
Period of Report: 2010-03-31

Reporting Person: Sabry James H (Former Executive Chairman)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2010-03-31	Common Stock	M	10000	$1.2	Acquired	10000	Direct
2010-03-31	Common Stock	S	1600	$3.22	Disposed	8400	Direct
2010-03-31	Common Stock	S	4800	$3.23	Disposed	3600	Direct
2010-03-31	Common Stock	S	300	$3.235	Disposed	3300	Direct
2010-03-31	Common Stock	S	2300	$3.24	Disposed	1000	Direct
2010-03-31	Common Stock	S	1000	$3.2425	Disposed	0	Direct

Derivative Transactions

Date	Security	Exercise Price	Code	Shares	A/D	Expiration	Underlying	Ownership
2010-03-31	Non-Qualified Stock Option (right to buy)	$1.2	M	10000	Disposed	2012-07-10	Common Stock (10000)	Direct

Holdings (Derivative)

Security	Exercise Price	Expiration	Underlying	Shares	Ownership
Incentive Stock Option (right to buy)	$0.58	2010-11-14	Common Stock (50267)	50267	Direct
Incentive Stock Option (right to buy)	$1.2	2012-07-10	Common Stock (7132)	7132	Direct
Incentive Stock Option (right to buy)	$1.2	2013-05-21	Common Stock (75000)	75000	Direct
Incentive Stock Option (right to buy)	$6.5	2014-03-08	Common Stock (66943)	66943	Direct
Incentive Stock Option (right to buy)	$6.59	2015-04-11	Common Stock (15154)	15154	Direct
Incentive Stock Option (right to buy)	$6.81	2017-03-14	Common Stock (11091)	11091	Direct
Incentive Stock Option (right to buy)	$7.15	2016-03-01	Common Stock (18464)	18464	Direct
Non-Qualified Stock Option (right to buy)	$6.5	2014-03-08	Common Stock (19557)	19557	Direct
Non-Qualified Stock Option (right to buy)	$6.59	2015-04-11	Common Stock (69846)	69846	Direct
Non-Qualified Stock Option (right to buy)	$6.81	2017-03-14	Common Stock (88909)	88909	Direct
Non-Qualified Stock Option (right to buy)	$7.15	2016-03-01	Common Stock (131536)	131536	Direct

Footnotes

F1: The exercise reported in this Form 4 was effected pursuant to a domestic relations court order.

F2: The sales reported in this Form 4 were effected pursuant to a domestic relations court order.

F3: When the ISO and NQ dated 07/10/02 are combined for a total grant of 300,000 shares, the option is immediately exercisable upon grant and shall vest as to 5,000 shares on 04/15/02 and the balance of 295,000 divided into equal monthly installments thereafter such that the option shall be 100% vested on 03/15/07.

F4: When the ISO and NQ dated 11/14/00 are combined for a total grant of 250,000 shares, the option is immediately exercisable upon grant and shall vest as to 4,167 shares on 12/14/00 and the balance of 245,833 divided into equal monthly installments thereafter such that the option shall be 100% vested on 11/14/05.

F5: This option is immediately exercisable upon grant and shall vest as to 1,563 shares on 04/01/03 and the balance of 73,437 divided into equal monthly installments thereafter such that the option shall be 100% vested on 03/01/07.

F6: When the ISO and NQ dated 03/08/04 are combined for a total grant of 86,500 shares, the option shall vest and become exercisable as to 1,802 shares on 04/08/04 and the balance of 84,698 divided into equal monthly installments thereafter such that the option shall be 100% vested on 03/08/08.

F7: When the ISO and NQ dated 04/11/05 are combined for a total grant of 85,000 shares, the option shall vest and become exercisable as to 85,000 shares divided into equal monthly installments such that the option shall be 100% vested on 03/01/2009.

F8: When the ISO and NQ dated 03/14/2007 are combined for a total grant of 100,000 shares, the option shall vest and become exercisable as to 2,083 shares on 04/01/07 and the balance of 97,917 divided into equal monthly installments thereafter such that the option shall be 100% vested on 03/01/11.

F9: When the ISO and NQ dated 03/01/2006 are combined for a total grant of 150,000 shares, the option shall vest and become exercisable as to 150,000 shares divided into equal monthly installments such that the option shall be 100% vested on 03/01/2010.