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CYTOKINETICS INC Director's Dealing 2010

May 20, 2010

30870_dirs_2010-05-20_7b2208e8-989b-4eb1-9365-0e08c5a8f047.zip

Director's Dealing

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SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: CYTOKINETICS INC (CYTK)
CIK: 0001061983
Period of Report: 2010-05-18

Reporting Person: Sabry James H (Former Executive Chairman)

Non-Derivative Transactions

Date Security Code Shares Price A/D Holdings After Ownership
2010-05-18 Common Stock M 25000 $0.58 Acquired 25000 Direct
2010-05-18 Common Stock S 200 $2.975 Disposed 24800 Direct
2010-05-18 Common Stock S 300 $2.98 Disposed 24500 Direct
2010-05-18 Common Stock S 100 $2.985 Disposed 24400 Direct
2010-05-18 Common Stock S 1600 $2.99 Disposed 22800 Direct
2010-05-18 Common Stock S 500 $2.9925 Disposed 22300 Direct
2010-05-18 Common Stock S 3400 $2.995 Disposed 18900 Direct
2010-05-18 Common Stock S 9300 $3 Disposed 9600 Direct
2010-05-18 Common Stock S 100 $3.005 Disposed 9500 Direct
2010-05-18 Common Stock S 1900 $3.01 Disposed 7600 Direct
2010-05-18 Common Stock S 400 $3.015 Disposed 7200 Direct
2010-05-18 Common Stock S 2365 $3.02 Disposed 4835 Direct
2010-05-18 Common Stock S 300 $3.025 Disposed 4535 Direct
2010-05-18 Common Stock S 1433 $3.03 Disposed 3102 Direct
2010-05-18 Common Stock S 100 $3.035 Disposed 3002 Direct
2010-05-18 Common Stock S 454 $3.04 Disposed 2548 Direct
2010-05-18 Common Stock S 848 $3.05 Disposed 1700 Direct
2010-05-18 Common Stock S 700 $3.06 Disposed 1000 Direct
2010-05-18 Common Stock S 1000 $3.07 Disposed 0 Direct

Derivative Transactions

Date Security Exercise Price Code Shares A/D Expiration Underlying Ownership
2010-05-18 Incentive Stock Option (right to buy) $0.58 M 25000 Disposed 2010-11-14 Common Stock (25000) Direct

Holdings (Derivative)

Security Exercise Price Expiration Underlying Shares Ownership
Incentive Stock Option (right to buy) $1.2 2012-07-10 Common Stock (7132) 7132 Direct
Incentive Stock Option (right to buy) $1.2 2013-05-21 Common Stock (75000) 75000 Direct
Incentive Stock Option (right to buy) $6.5 2014-03-08 Common Stock (66943) 66943 Direct
Incentive Stock Option (right to buy) $6.59 2015-04-11 Common Stock (15154) 15154 Direct
Incentive Stock Option (right to buy) $6.81 2017-03-14 Common Stock (11091) 11091 Direct
Incentive Stock Option (right to buy) $7.15 2016-03-01 Common Stock (18464) 18464 Direct
Non-Qualified Stock Option (right to buy) $1.2 2012-07-10 Common Stock (75455) 75455 Direct
Non-Qualified Stock Option (right to buy) $6.5 2014-03-08 Common Stock (19557) 19557 Direct
Non-Qualified Stock Option (right to buy) $6.59 2015-04-11 Common Stock (69846) 69846 Direct
Non-Qualified Stock Option (right to buy) $6.81 2017-03-14 Common Stock (88909) 88909 Direct
Non-Qualified Stock Option (right to buy) $7.15 2016-03-01 Common Stock (131536) 131536 Direct

Footnotes

F1: When the ISO and NQ dated 11/14/00 are combined for a total grant of 250,000 shares, the option is immediately exercisable upon grant and shall vest as to 4,167 shares on 12/14/00 and the balance of 245,833 divided into equal monthly installments thereafter such that the option shall be 100% vested on 11/14/05.

F2: When the ISO and NQ dated 07/10/02 are combined for a total grant of 300,000 shares, the option is immediately exercisable upon grant and shall vest as to 5,000 shares on 04/15/02 and the balance of 295,000 divided into equal monthly installments thereafter such that the option shall be 100% vested on 03/15/07.

F3: This option is immediately exercisable upon grant and shall vest as to 1,563 shares on 04/01/03 and the balance of 73,437 divided into equal monthly installments thereafter such that the option shall be 100% vested on 03/01/07.

F4: When the ISO and NQ dated 03/08/04 are combined for a total grant of 86,500 shares, the option shall vest and become exercisable as to 1,802 shares on 04/08/04 and the balance of 84,698 divided into equal monthly installments thereafter such that the option shall be 100% vested on 03/08/08.

F5: When the ISO and NQ dated 04/11/05 are combined for a total grant of 85,000 shares, the option shall vest and become exercisable as to 85,000 shares divided into equal monthly installments such that the option shall be 100% vested on 03/01/2009.

F6: When the ISO and NQ dated 03/14/2007 are combined for a total grant of 100,000 shares, the option shall vest and become exercisable as to 2,083 shares on 04/01/07 and the balance of 97,917 divided into equal monthly installments thereafter such that the option shall be 100% vested on 03/01/11.

F7: When the ISO and NQ dated 03/01/2006 are combined for a total grant of 150,000 shares, the option shall vest and become exercisable as to 150,000 shares divided into equal monthly installments such that the option shall be 100% vested on 03/01/2010.