ContextVision AB — Investor Presentation 2020

Jun 12, 2020

ContextVision

Company presentation

Fredrik Palm, CEO

June 12, 2020

@ Sparebank 1 Markets Webinar

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ContextVision – a medical technology software company specializing in image analysis and artificial intelligence, for image-based applications.

BUSINESS AREAS

Medical Imaging

Globally established market leaders

Digital Pathology

Soon to enter the market, huge potential

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ContextVision – brief facts

• ~50 employees (50% within R&D)
• World-leading product development based on machine learning
• Over 35 years’ experience within image processing and image analysis for medical applications
• Over 300,000 system installations worldwide

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We know what we do...

Home Background Rules Data Evaluation Forum Organisers Workshop Join Results

Results

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We apply technology with focus on application

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Healthcare challenges

Increase in the elderly population

Healthcare cost US, share of GDP

Increased incidence of cancer
Healthcare cost EU, share of GDP

Source: https://www.nia.nih.gov/research/publication/global-health-and-aging/assessing-costs-aging-and-health-care

Sources: Cap Gemini (EU) and Sisko A.M. et al. (2014), "National health expenditure projections, 2013–23: faster growth expected with expanded coverage and improving economy"

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Aiming towards treatment guidance

• Improve workflow
• Improve precision
• Use follow up data
• Use outcome data

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Simplified illustration of the patient journey

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Process of excellence – industrial grade

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8 June 2020

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Medical Imaging

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Image enhancement

Our state-of-the-art software portfolio

Ultrasound 2D
US PlusView™ 2.0
VolarView™

Ultrasound 3D/4D
GOPICE® 2.0

Ultrasound 3D/4D & Visualization
REALICE®

Radiography
Altumira™

Radiography – Dynamic
Altumira™ Plus

Mammography
GOPView® Mammo3

MRI
GOPView® MRI2Plus

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Altumira™ – the new generation of AI-based X-ray image enhancement

Gold standard image quality

Robustness between patients and varying exposure conditions

Processed with Altumira
Standard processing

Rivent™ – the 7th generation of image enhancement for ultrasound

Processed Ultrasound - Abdomen

MRI- Abdomen

Disclaimer – the image examples is only an sharpness illustration of the images. It does not reflect clinical information

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Medical Imaging – summary

• Global market leader within medical imaging for ultrasound, X-ray, MRI and mammography
• Revenues are dominated by long-term license fees and driven by customers' production rates and product life cycles
• >300,000 systems worldwide are equipped with ContextVision's software
• Combining 35 years of experience in image processing with the latest AI technology, to continuously deliver cutting-edge products to the market

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Digital Pathology

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A young, rapidly growing market

Digital pathology is a rapidly growing market driven by the shortage of pathologists worldwide. Going digital enables use of decision support tools that make pathologists' work more efficient.

DIGITAL PATHOLOGY

• Provides easy access to specialists
• Means a new, more efficient workflow
• Opens for automated image analysis

Automated image analysis has the potential to radically transform the diagnosis process and improve patient care.

ANALOGUE

DIGITAL

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Market estimations

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INIFY® – decision support tools

• ContextVision is developing a portfolio of decision support tools targeting major cancer diseases
• The tools are developed by training Deep Learning networks, using high quality data and annotations
• Each year ~2.3 billion prostate biopsy procedures are performed in Europe and the USA
• Other areas with a heavy pathology lab workload are colon, lung and breast cancer
• First product – INIFY Prostate Screening

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NOTE! INIFY® Prostate Screening is an investigational device, not yet CE-marked for clinical use
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First product – INIFY® Prostate Screening

Outlines suspicious cancer areas in each prostate biopsy

Viewer provides a smooth, intuitive user experience

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NOTE! INIFY® Prostate Screening is an investigational device, not yet CE-marked for clinical use
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MasterAnnotation™ – a unique, patented method

Generates close-to-ground-truth data for training our Deep Learning networks

A multiplex immunofluorescence overlay is combined with H&E staining on the same tissue slide for exact identification of suspicious cancer areas

Patent US 10,572,996

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NOTE! INIFY® Prostate Screening is an investigational device, not yet CE-marked for clinical use

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INIFY® Prostate Screening – workflow

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NOTE! INIFY® Prostate Screening is an investigational device, not yet CE-marked for clinical use

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INIFY® Prostate Screening – integrated in clinical workflow since 2018

FILIPPO FRAGGETTA, MD

"It is so easy to use... just scan the slides and you will have the answer automatically on your tray within your LIS."

Original Article

Routine Digital Pathology Workflow: The Catania Experience

Filippo Fraggetta¹, Salvatore Garozzo¹, Gian Franco Zannoni², Liron Pantanowitz³, Esther Diana Rossi³

¹Pathology Unit, Cannizzaro Hospital, Catania, ²Division of Anatomic Pathology and Histology, School of Medicine, ³Igostino Gemelli⁴, Rome, Italy, ⁴Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA

Received: 21 August 2017
Accepted: 10 October 2017
Published: 19 December 2017

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NOTE! INIFY® Prostate Screening is an investigational device, not yet CE-marked for clinical use
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Digital Pathology – summary

• With an unmatched experience within algorithm based software products development for image based applications...
• We Invest significantly in a computational pathology business to enter the rapidly developing digital pathology market...
• and develops decision support tools for pathologists, focusing on cancer types that create the heaviest workload
• Our first product: INIFY® Prostate Screening

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NOTE! INIFY® Prostate Screening is an investigational device, not yet CE-marked for clinical use
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ContextVision – summary

• At the forefront of image processing and decision support technology
• Delivering software solutions that address today’s healthcare challenges, enabling radical transformation
• About to enter the fast-growing Digital Pathology market
• An established company, market leaders within image processing for Medical Imaging, now adding digital pathology and aiming at treatment guidance.
• COVID-19 comments

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