Compugen Ltd.

Proxy Solicitation & Information Statement • Mar 14, 2010

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C007�������� ��"�2PublicCOMPUGEN LTD.7411Corporation no: 511779639Stock Exchange/Market: ��������606428Pinchas Rosen 72 , Tel Aviv 69512 , ,Tel: 03-7658585 , 03-7658525 Fax: 03-7658555E.mail address: dikla@compugen.co.ilDate of transmission: 14/03/2010              Time of broadcast: 09:01 08:58:37

Reference: 2010-02-412149

Israel Securities Authority		Tel Aviv Stock Exchange
www.isa.gov.il		www.tase.co.il

Annual General Meeting / Special MeetingRegulation 5 of the Securities Regulations, (Periodic and Immediate Reports of Foreign Corporation) 5761-2000Only for corporation incorporated in Israel

On 15/04/2010 at 10:00 the corporation will hold it's annual general meetingat 72 Pinchas Rosen st. Tel-AvivNumber of the security that entitles its holder to vote at the meeting: 33119432The Number - as given by the Tel Aviv Stock Exchange

According to section 182 B of the Companies law, 5759-1999, only shareholders of record at the close of business 09/03/2010 will be entitled to notice of, and to vote at, the Meeting.

Attached hereto is the report 6-kMar142010_isa.pdf

Attached hereto is the proxy statement 6-kMar142010P_isa.pdf

References of previous documents relating to this matter(the reference does not constitute incorporation by reference):
Previous names of reporting entity:
Date of revision of form structure: 10/03/2010
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Name of the Signatory: : Czaczkes Axselbard Dikla , Position of Signatory in the reporting corporation: Chief Financial Officer , Name of Employer Company: .
Pinchas Rozen Telephone: 03-7658585 , Facsimile: 03-7658555 , E-mail: dikla@cgen.com 2