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CLINUVEL PHARMACEUTICALS LIMITED — Management Reports 2021
Jan 24, 2021
64726_rns_2021-01-24_224568f2-1e6f-4136-9b6e-63ec49411dec.pdf
Management Reports
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We have entered a new year, one brimmed with optimism and hanging our hopes on the reversal of global health and the restart of our economies
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On the historical day of 20 January, we record the anniversary of the first COVID case reported in South Korea
COVID Update
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₀
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I also postulate that the current vaccination programs will rapidly exert their effects in Europe – and in the future, in developing nations across the world
Creeping Inflation and Impact on
Pharmaceuticals
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Central banks are continuing to inject liquidity in the markets, while credit to small businesses and households is slowing down in the EU
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CLINUVEL’s Year Ahead
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By design, the Group has been strengthened to diversify its activities
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US-EU-AU Distribution
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In Q4 2020, a landmark event has been the approval of code J7352 for SCENESSE®
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The commercial status quo on 1 January 2021 is that SCENESSE® is now listed at a uniform price across all US states, with a designated J-code
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DNA Regeneration Program
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We are analysing the DNA reparative properties in melanocortins in man
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Single-strand DNA damage is a well-known phenomenon occurring in all of us following UV exposure
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CLINUVEL’s stroke program focuses on ischaemic stroke, responsible for 85-87% of all stroke cases, which arise from physical obstruction of blood vessels. For an indepth look at the vascular system, see Scientific Communique VII
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PRÉNUMBRA®
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| Differences in Afamelanotide Formulations SCENESSE® PRÉNUMBRA® Key pharmaceutical ingredient Afamelanotide Afamelanotide Polymers Yes Yes Injectable Yes Yes Route of administration Subcutaneous Subcutaneous Dissolvable Yes Yes Removable Yes No Dosing Fixed Flexible Patients Adults Adults Administration Byaphysician Byaphysician Self-injectable No No Category Chronic, EPP Acute, life threatening Toxicologyknown Yes Yes |
Differences in Afamelanotide Formulations SCENESSE® PRÉNUMBRA® Key pharmaceutical ingredient Afamelanotide Afamelanotide Polymers Yes Yes Injectable Yes Yes Route of administration Subcutaneous Subcutaneous Dissolvable Yes Yes Removable Yes No Dosing Fixed Flexible Patients Adults Adults Administration Byaphysician Byaphysician Self-injectable No No Category Chronic, EPP Acute, life threatening Toxicologyknown Yes Yes |
Differences in Afamelanotide Formulations SCENESSE® PRÉNUMBRA® Key pharmaceutical ingredient Afamelanotide Afamelanotide Polymers Yes Yes Injectable Yes Yes Route of administration Subcutaneous Subcutaneous Dissolvable Yes Yes Removable Yes No Dosing Fixed Flexible Patients Adults Adults Administration Byaphysician Byaphysician Self-injectable No No Category Chronic, EPP Acute, life threatening Toxicologyknown Yes Yes |
|---|---|---|
| Differences in Afamelanotide Formulations | ||
| SCENESSE® | PRÉNUMBRA® | |
| Key pharmaceutical ingredient |
Afamelanotide | Afamelanotide |
| Polymers | Yes | Yes |
| Injectable | Yes | Yes |
| Route of administration |
Subcutaneous | Subcutaneous |
| Dissolvable | Yes | Yes |
| Removable | Yes | No |
| Dosing | Fixed | Flexible |
| Patients | Adults | Adults |
| Administration | Byaphysician | Byaphysician |
| Self-injectable | No | No |
| Category | Chronic, EPP | Acute, life threatening |
| Toxicologyknown | Yes | Yes |
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Human Resources
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The intrinsic value of the Company is encapsulated largely by its staff.
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Public and Investor Relations
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H.C. Wainwright Bioconnect was an early opportunity to gauge how well CLINUVEL is positioned to diversify and grow.
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30.00 12
10
25.00 8
6
20.00 4
2
15.00 0
Share Price, A$ Close (LHS) Aggregate Shorts, % of Issued Shares (RHS)
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Conclusion
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$45,000 $350,000
$40,000
$300,000
$35,000
$250,000
$30,000
$25,000 $200,000
$20,000 $150,000
$15,000
$100,000
$10,000
$50,000
$5,000
$0 $0
06 07 08 09 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24
Financial Year A$ Cash Used
Cumul. Expend.
Cash Used A$'000
Cumulative Expenditure A$'000
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In 2021 we strive and expect to outshine previous years as we build out the group of companies.
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Share price
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ASX: CUV 22 January 2018 – 22 January 2021
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$45 49,410,338
49,548,671
$40
A$1.07bn
$35
$30
$25
$20
$15
$10
$5
22-Jan-18 22-Jul-18 22-Jan-19 22-Jul-19 22-Jan-20 22-Jul-20 22-Jan-21
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Contact
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