Clene Inc. — Major Shareholding Notification 2024

Feb 13, 2024

SC 13G/A 1 ea193544-13ga1vivo_clene.htm AMENDMENT NO. 1 TO SCHEDULE 13G

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UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

SCHEDULE 13G/A

UNDER THE SECURITIES EXCHANGE ACT OF 1934

(Amendment No. 1)*

Clene, Inc.

(Name of Issuer)

Common Stock, $0.0001 par value per share

(Title of Class of Securities)

185634102

(CUSIP Number)

December 31, 2023

(Date of Event Which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

☐ Rule 13d-1(b)

þ Rule 13d-1(c)

☐ Rule 13d-1(d)

• The remainder of this cover page shall be filled out for a reporting person’s initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior cover page.

The information required in the remainder of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934 (“Act”) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).

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| 1. | NAMES
OF REPORTING PERSONS Vivo
Opportunity Fund Holdings, L.P. |
| --- | --- |
| 2. | CHECK
THE APPROPRIATE BOX IF A MEMBER OF A GROUP (a)
☐ (b) þ |
| 3. | SEC
USE ONLY |
| 4. | CITIZENSHIP
OR PLACE OF ORGANIZATION Delaware |

| NUMBER
OF SHARES BENEFICIALLY OWNED
BY EACH REPORTING PERSON WITH | SOLE
VOTING POWER 12,500,000
(1)(2) |
| --- | --- |
| 6. | SHARED
VOTING POWER 0 |
| 7. | SOLE
DISPOSITIVE POWER 12,500,000
(1)(2) |
| 8. | SHARED
DISPOSITIVE POWER 0 |

| 9. | AGGREGATE
AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 12,500,000
(1)(2) |
| --- | --- |
| 10. | CHECK
BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES ☐ |
| 11. | PERCENT
OF CLASS REPRESENTED BY AMOUNT IN ROW 9 7.0%
(2) |
| 12. | TYPE
OF REPORTING PERSON PN |

(1) The number represents (i) 6,250,000 shares of common stock, par value $0.0001 per share (the “ Common Stock ”) of Clene, Inc. (the “ Issuer ”) issuable upon exercise of Tranche A warrants that are exercisable within 60 days of this Statement, and (ii) 6,250,000 shares of Common Stock issuable upon exercise of Tranche B warrants that are exercisable within 60 days of this Statement. All securities are held of record by Vivo Opportunity Fund Holdings, L.P. Vivo Opportunity, LLC is the general partner of Vivo Opportunity Fund Holdings, L.P. The Tranche A warrants and Tranche B warrants contain provisions preventing the warrants from being exercised if such exercise would result in the holder obtaining greater than 9.99% of the Issuer’s voting securities.

(2) Based on 167,095,337 shares of the Issuer’s Common Stock to be outstanding after the at the market offering of the Issuer, as disclosed in the prospectus filed by the Issuer on November 7, 2023, pursuant to Rule 424(b)(5), which forms part of the Issuer’s Registration Statement on Form S-3 (File No. 333-264299), plus the shares of Common Stock exercisable upon exercise of Tranche A warrants and Tranche B warrants.

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| 1. | NAMES
OF REPORTING PERSONS Vivo
Opportunity, LLC |
| --- | --- |
| 2. | CHECK
THE APPROPRIATE BOX IF A MEMBER OF A GROUP (a)
☐ (b) þ |
| 3. | SEC
USE ONLY |
| 4. | CITIZENSHIP
OR PLACE OF ORGANIZATION Delaware |

| NUMBER
OF SHARES BENEFICIALLY OWNED
BY EACH REPORTING PERSON WITH | SOLE
VOTING POWER 12,500,000
(1)(2) |
| --- | --- |
| 6. | SHARED
VOTING POWER 0 |
| 7. | SOLE
DISPOSITIVE POWER 12,500,000
(1)(2) |
| 8. | SHARED
DISPOSITIVE POWER 0 |

| 9. | AGGREGATE
AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 12,500,000
(1)(2) |
| --- | --- |
| 10. | CHECK
BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES ☐ |
| 11. | PERCENT
OF CLASS REPRESENTED BY AMOUNT IN ROW 9 7.0%
(2) |
| 12. | TYPE
OF REPORTING PERSON OO |

(1) The number represents (i) 6,250,000 shares of Common Stock issuable upon exercise of Tranche A warrants that are exercisable within 60 days of this Statement, and (ii) 6,250,000 shares of Common Stock issuable upon exercise of Tranche B warrants that are exercisable within 60 days of this Statement. All securities are held of record by Vivo Opportunity Fund Holdings, L.P. Vivo Opportunity, LLC is the general partner of Vivo Opportunity Fund Holdings, L.P. The Tranche A warrants and Tranche B warrants contain provisions preventing the warrants from being exercised if such exercise would result in the holder obtaining greater than 9.99% of the Issuer’s voting securities.

(2) Based on 167,095,337 shares of the Issuer’s Common Stock to be outstanding after the at the market offering of the Issuer, as disclosed in the prospectus filed by the Issuer on November 7, 2023, pursuant to Rule 424(b)(5), which forms part of the Issuer’s Registration Statement on Form S-3 (File No. 333-264299), plus the shares of Common Stock exercisable upon exercise of Tranche A warrants and Tranche B warrants.

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ITEM 1. Issuer

(a)	Name of Issuer:
	Clene, Inc. (the “ Issuer ”)
(b)	Address of Issuer’s Principal
Executive Offices:
	6550 South Millrock Drive,
Suite G50 Salt Lake City, Utah, 84121

ITEM 2. Filing Person

(a) – (c) Name of Persons Filing; Address; Citizenship:

| | (i) | Vivo Opportunity Fund Holdings,
L.P., a Delaware limited partnership; and |
| --- | --- | --- |
| | (ii) | Vivo Opportunity, LLC, a Delaware
limited liability company. Vivo Opportunity, LLC is the general partner of Vivo Opportunity Fund Holdings, L.P. |
| The address of
the principal business office of the Reporting Persons is 192 Lytton Avenue, Palo Alto, CA 94301. | | |
| (d) | Title of Class
of Securities: | |
| | Common Stock, par
value $0.0001 per share (“ Common Stock ”). | |
| (e) | CUSIP Number: | |
| | 185634102 | |

ITEM 3. If this statement is filed pursuant to Rules 13d-1(b), or 13d-2(b) or (c), check whether the person filing is a:

| (a) | ☐ | Broker or dealer registered under Section 15 of the
Act; |
| --- | --- | --- |
| (b) | ☐ | Bank as defined in Section 3(a)(6) of the Act; |
| (c) | ☐ | Insurance company as defined in Section 3(a)(19) of
the Act; |
| (d) | ☐ | Investment company registered under Section 8 of the
Investment Company Act of 1940; |
| (e) | ☐ | An investment adviser in accordance with Rule 13d-1(b)(1)(ii)(E); |
| (f) | ☐ | An employee benefit plan or endowment fund in accordance
with Rule 13d-1(b)(1)(ii)(F); |
| (g) | ☐ | A parent holding company or control person in accordance
with Rule 13d-1(b)(1)(ii)(G); |
| (h) | ☐ | A savings associations as defined in Section 3(b) of
the Federal Deposit Insurance Act (12 U.S.C. 1813); |
| (i) | ☐ | A church plan that is excluded from the definition
of an investment company under section 3(c)(14) of the Investment Company Act of 1940; |
| (j) | ☐ | A non-U.S. institution in accordance with Rule 240.13d-1(b)(1)(ii)(J); |
| (k) | ☐ | Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).
If filing as a non-U.S. institution in accordance with Rule 240.13d-1(b)(1)(ii)(J), please specify the type of institution: |
| | If filing as a non-U.S. institution in accordance with §240.13d-1(b)(1)(ii)(J), please specify the type of institution: | |

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ITEM 4. Ownership.

| (a) and (b) | Amount beneficially
owned: |
| --- | --- |
| | The information set forth
in rows 5 through 11 of the cover pages is incorporated by reference into this Item 4. |
| | The shares reported in
this Schedule 13G/A include (i) 6,250,000 shares of Common Stock issuable upon exercise of Tranche A warrants that are exercisable
within 60 days of this Statement, and (ii) 6,250,000 shares of Common Stock issuable upon exercise of Tranche B warrants that are
exercisable within 60 days of this Statement. All securities are held of record by Vivo Opportunity Fund Holdings, L.P. Vivo Opportunity,
LLC is the general partner of Vivo Opportunity Fund Holdings, L.P. |
| | The Tranche A warrants and Tranche B warrants contain
provisions preventing the warrants from being exercised if such exercise would result in the holder obtaining greater than 9.99%
of the Issuer’s voting securities. |
| (c) | Number of shares as to which such person has: |

| Reporting
Person — Vivo Opportunity
Fund Holdings, L.P. | 12,500,000 | 0 | 12,500,000 | 0 | 7.0 | % |
| --- | --- | --- | --- | --- | --- | --- |
| Vivo Opportunity, LLC | 12,500,000 | 0 | 12,500,000 | 0 | 7.0 | % |

• The percent of class was based on 167,095,337 shares of the Issuer’s Common Stock to be outstanding after the at the market offering of the Issuer, as disclosed in the prospectus filed by the Issuer on November 7, 2023, pursuant to Rule 424(b)(5), which forms part of the Issuer’s Registration Statement on Form S-3 (File No. 333-264299), plus the shares of Common Stock exercisable upon exercise of Tranche A warrants and Tranche B warrants.

ITEM 5. Ownership of Five Percent or Less of a Class.

Not applicable.

ITEM 6. Ownership of More than Five Percent on Behalf of Another Person.

Not applicable.

ITEM 7. Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.

Not applicable.

ITEM 8. Identification and Classification of Members of the Group.

Not applicable.

ITEM 9. Notice of Dissolution of Group.

Not applicable.

ITEM 10. Certification.

By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under §240.14a-11.

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SIGNATURE

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

Date: February 13, 2024

| VIVO
OPPORTUNITY FUND HOLDINGS, L.P, | |
| --- | --- |
| By: | Vivo
Opportunity, LLC |
| Its: | General Partner |
| /s/
Kevin Dai | |
| Name: | Kevin Dai |
| Title: | Managing Member |
| VIVO
OPPORTUNITY, LLC | |
| /s/
Kevin Dai | |
| Name: | Kevin Dai |
| Title: | Managing Member |

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