CAMBIUM BIO LIMITED — Director's Dealing 2014

Nov 5, 2014

6 November 2014

ASX Ltd 20 Bridge Street Sydney NSW 2000

Subscription for shares and options by Directors

Attached for immediate release to the market are the following documents:

• Appendix 3Y Change of Director's Interest Notice John Martin $\bullet$
• Appendix 3Y Change of Director's Interest Notice Graham Vesey $\bullet$

The Chairman and CEO have taken up additional shares in the company, which were subscribed for in the \$3M private placement paying an aggregate of \$200,000 at \$0.26c per share, following shareholder approval at the Annual General Meeting held on 28 October 2014.

The company had raised \$3 million from the private placement, announced on 15 August 2015.

This should send a positive message to investors, as the company continues to progress its initiatives in the development and commercialisation of its regenerative medicine products.

Yours faithfully

John Martin Executive Chairman

÷

$\overline{2}$

Rule 3.19A.2

Appendix 3Y

Change of Director's Interest Notice

Information or documents not available now must be given to ASX as soon as available. Information and documents given to ASX become ASX's property and may be made public.

Introduced 30/09/01 Amended 01/01/11

	Name of entity Regeneus Ltd
	ABN 13 127 035 358			---------

We (the entity) give ASX the following information under listing rule 3.19A.2 and as agent for the director for the purposes of section 205G of the Corporations Act.

Name of Director	John Martin
Date of last notice	n/a

Part 1 - Change of director's relevant interests in securities

In the case of a trust, this includes interests in the trust made available by the responsible entity of the trust

Note: In the case of a company, interests which come within paragraph (i) of the definition of "notifiable interest of a director" should be disclosed in this part.

Direct or indirect interest	Direct
Nature of indirect interest	n/a
(including registered holder) Note: Provide details of the circumstances giving rise to the relevant interest.
Date of change	6 November 2014
No. of securities held prior to change	6,689,292 Ordinary Shares; and 2,680,355 Options over ordinary shares.
Class	Ordinary Shares
Number acquired	384,616 Ordinary Shares; and 128,205 Options over ordinary shares
Number disposed	n/a
Value/Consideration	Shares - \$100,000
Note: If consideration is non-cash, provide details and estimated valuation	Options – Nil
No. of securities held after change	7,073,908 Ordinary Shares; and 2,808,560 Options over ordinary shares

01/01/2011 Appendix 3Y Page 1

⁺ See chapter 19 for defined terms.

buy-back	Nature of change . Example: on-market trade, off-market trade, exercise of options, $\mid$ $\mathbf{Placement}$ issue of securities under dividend reinvestment plan, participation in		Issue of securities	under	Private

Part 2 - Change of director's interests in contracts

Note: In the case of a company, interests which come within paragraph (ii) of the definition of "notifiable interest of a director" should
be disclosed in this part.

n/a
n/a
n/a
n/a
n/a
n/a
n/a
n/a
n/a

Part 3 - ⁺Closed period

Were the interests in the securities or $ $ No contracts detailed above traded during a +closed period where prior written clearance was required?
If so, was prior written clearance provided $\mid n/a \mid$ to allow the trade to proceed during this period?

⁺ See chapter 19 for defined terms.

If prior written clearance was provided, on
what date was this provided?

$\ddot{\cdot}$

$\sim$

⁺ See chapter 19 for defined terms.

$\hat{\vec{x}}$

$\hat{\mathbf{r}}$

Rule 3.19A.2

Appendix 3Y

Change of Director's Interest Notice

Information or documents not available now must be given to ASX as soon as available. Information and documents given to ASX become ASX's property and may be made public.

Introduced 30/09/01 Amended 01/01/11

$\mathbb{R}^2$

Name of entity Regeneus Ltd
ABN 13 127 035 358

We (the entity) give ASX the following information under listing rule 3.19A.2 and as agent for the director for the purposes of section 205G of the Corporations Act.

Name of Director	Graham Vesey
Date of last notice	n/a

Part 1 - Change of director's relevant interests in securities

In the case of a trust, this includes interests in the trust made available by the responsible entity of the trust

Note: In the case of a company, interests which come within paragraph (i) of the definition of "notifiable interest of a director" should be disclosed in this part.

Direct or indirect interest	Direct
Nature of indirect interest (including registered holder) Note: Provide details of the circumstances giving rise to the relevant interest.	n/a
Date of change	6 November 2014
No. of securities held prior to change	15,495,352 Ordinary Shares; and 2,142,855 Options over ordinary shares.
Class	Ordinary Shares
Number acquired	384,616 Ordinary Shares; and 128,206 Options over ordinary shares
Number disposed	n/a
Value/Consideration Note: If consideration is non-cash, provide details and estimated valuation	$Shares - $100,000$ Options - Nil
No. of securities held after change	15,879,968 Ordinary Shares; and 2,271,061 Options over ordinary shares

⁺ See chapter 19 for defined terms.

Nature of change Example: on-market trade, off-market trade, exercise of options, J $^{-1}$ issue of securities under dividend reinvestment plan, participation in $^{-1}$ buy-back	Issue → I Placement	0t.	securities	under	Private

Part 2 - Change of director's interests in contracts

Note: In the case of a company, interests which come within paragraph (ii) of the definition of "notifiable interest of a director" should
be disclosed in this part.

Detail of contract	n/a
Nature of interest	n/a
Name of registered holder (if issued securities)	n/a
Date of change	n/a
No. and class of securities to which interest related prior to change Note: Details are only required for a contract in relation to which the interest has changed	n/a
Interest acquired	n/a
Interest disposed	n/a
Value/Consideration Note: If consideration is non-cash, provide details and an estimated valuation	n/a
Interest after change	n/a

Part 3 - ⁺Closed period

Were the interests in the securities or $\mid$ $\mathrm{No}\mid$ contracts detailed above traded during a tclosed period where prior written" clearance was required?
$\vert$ If so, was prior written clearance provided $\vert$ $n/a$ to allow the trade to proceed during this period?

⁺ See chapter 19 for defined terms.

$\hat{\mathcal{A}}$

If prior written clearance was provided, on
what date was this provided?

$\frac{1}{\sqrt{2}}$

$\frac{1}{2}$ .

⁺ See chapter 19 for defined terms.

$\mathcal{L}^{\text{max}}_{\text{max}}$

$\label{eq:V} \hat{V} = \frac{1}{2\pi\epsilon_0^2}$