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Biotest AG — Investor Presentation 2013
May 8, 2013
66_rns_2013-05-08_32837587-25c8-4b3c-a0bb-dda1326d81ad.pdf
Investor Presentation
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Biotest AG Annual Shareholders' Meeting 2013
Prof. Dr. Gregor Schulz Chairman of the Board of Management
Biotest Strategy for 2020
Investments. Expansion. Future
Cornerstones of the Biotest Strategy
Internationalisation
Marketing authorisation in further markets
Research and Development
Additional indications, new developments
Focus
Haematology, clinical immunology, intensive care medicine
Continue and accelerate growth
* On a comparable basis, only pharmaceutical activities
Biotest AG Annual Shareholders' Meeting 2013
Figures for FY 2012 and Q1 2013
Sales grow in line with expectations
01002003004005002011 2012440.0 422.0+4.3%Germany Rest of Europe North/South AmericaAsiaOther161.596.9121.858.5160.589.477.611.174.99.8
Sales by region* (€ million)
* Continuing Operations
Significant earnings increase
Financial position: stronger equity base
Financial Position of the Biotest Group (€ million)
Biotest AG - Annual Shareholders' Meeting 2013
Good start to financial year 2013
Biotest AG - Annual Shareholders' Meeting 2013
Biotest stock: attractive investment
Biotest AG share price performance vs. SDAX
Closing price on 10th of May 2012 = 100
SDax Biotest ordinary shareBiotest preference share
- • Dividends for 2012*:
- € 0.50 per ordinary share
- € 0.56 per preference share
- • 5th consecutive dividend increase
- • Shareholder return**: 29% (ordinary shares) 33% (preference shares)
* Proposal of the Board of Management and Supervisory Board to the ASM
** Performance May 2012/2013 plus dividend for 2012 (as of 06.05.2013)
Biotest AG Annual Shareholders' Meeting 2013
Corporate Development and Strategy
Milestones in 2012
- •US authorisation for BivigamTM
- •Existing products further developed (including Intratect® 10%)
- •International position improved
- •Progress made in research and development
BivigamTM strengthens position in the US
- • Polyspecific intravenous immunoglobulin, comparable to Intratect®
- •FDA authorisation in December 2012
- •Excellent efficacy and safety profile
- • Successful launch in February 2013, sales volume in line with expectations
- • Medium-term market potential: USD 100 million per year
Targeted development of Intratect ®
- • Intratect ®10%
- •Immunoglobulin with higher doses
- •Geared to outpatient therapy
- •Allows faster administration
- • 5% solution remains first choice for inpatient treatment
Business further internationalised
Biotest: Sales by region 2012
China: moving into a growth market
- • China is world's third-largest pharmaceutical market
- •Double-digit growth rates
- • Market entry through reactivation of albumin authorisation
- • Distribution partnership with leading Chinese pharmaceutical company
Immunoglobulin sales boosted
Central/South America
- • Focus on hepatitis B immunoglobulins:
- − Hepatect ®
- Zutectra®
- • Focus markets: Brazil, Mexico, Colombia, Argentina
Russia
- • Distribution partnership with Merz Pharma for immunoglobulins
- • Utilize established distribution channels for Haemoctin® (tender contract business)
Greece: meeting our responsibility
- • Supply to Greek hospitals resumed in early 2013
- •Distribution agreement with Vianex
- • Strict protections for receivables:
- advance payment or German bank guarantee
- • Sales from January to April 2013: € 2.2 million
Development projects are making progress
Civacir® – immunoglobulin with high potential
- • Hepatitis C immunoglobulin for reinfection prophylaxis after liver transplantation
- • "Orphan drug designation" in Europe and US: 10- and 7-year exclusivity after authorisation (respectively)
- • Very high demand:
- − Currently no reliable prophylaxis for the critical period immediately after transplantation
- − In the EU and US alone, more than 5,000 liver transplants due to hepatitis C each year
Tregalizumab – taking the next step
- • Lead indications of rheumatoid arthritis (RA) and psoriasis
- •Partnership with AbbVie (formerly Abbott)
- • Start of phase IIb study with up to 350 patients in the US, Canada and Europe in Q2 2013
- •Largest clinical trial in Biotest history
Partnership with ADMA: agreement brings additional potential for Biotest
US biotech company
Focus on special therapeutic immunoglobulins for treatment of rare diseases
- • BPC supplies plasma with very high titres of RSV antibodies and produces this immunoglobulin for ADMA
- • Biotest acquires license to market and sell the product in Europe and selected countries in North Africa and the Middle East
- • ADMA is in preparation for a phase III trial in the US
IgM concentrate: development on target
- • IgM concentrate for effective treatment of sepsis (severe bacterial infection)
- •Unique mechanism of action
- • Interim analysis of ongoing phase II trial: continuation of development clearly recommended
Fibrinogen – start of clinical development
- •Fibrinogen deficiency causes severe bleeding
- • Fibrinogen from Biotest infusion-ready very quickly
- •Phase I/II study began in Q1 2013
- •Sales potential: about € 100 million/year
- •Better use of raw material blood plasma
Biotest AG Annual Shareholders' Meeting 2013
Investments. Expansion. Future Biotest 2020 strategy
Demand for immunoglobulins continues to grow
USA EUOther
| W l d o r : |
% 7 |
|---|---|
| O h t e r : |
1 2 % |
| S U A : |
4 % 5 |
| E U : |
4 5 % |
| E d l t t p e c e o n g e r m x - l h * t a n n a g r o u w |
* Estimates excluding possible potential in Alzheimer's
Source of all data: MRB (2012)
Investments in further growth
Expansion of global capacity to:
Plasma fractionation:
3.1 million litres/year currently: 1.5 m litres/year
Immunoglobulins:
13 t/year currently: 5.5 t/year
Albumin:
72 t/year currently: 21 t/year
- • Capacity expansion programme in Dreieich
- • Construction of new production plants at HQ
- •Duration: 2013 to 2018
- •Investment: > € 200 million
- •More than 300 additional jobs
* excluding already initiated projects (e.g. filling expansion)
Capital increase as an important financing element
- • Increase share capital by € 3.7 million or 12.5%
- • Issue up to 1.46 million new preference shares from authorised capital
- • Subscription right for all shareholders (ordinary shares + preference shares)
- •Planned for summer 2013
Vision – our road to 2020
- • Consistent focus on biological drugs for the therapeutic areas of haematology, immunology and intensive care medicine
- • Continuous investment in the development of new therapeutic options
- • Worldwide operations with a strong base in Europe and the US
- •Awareness of responsibilities
- •Focused on growth