BIOTECH

Major Shareholding Notification • Oct 17, 2014

National Storage Mechanism | Additional information

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THE BIOTECH GROWTH TRUST PLC - Holding(s) in Company

PR Newswire

London, October 17

For filings with the FCA include the annexFor filings with issuer exclude the annexTR-1: NOTIFICATION OF MAJOR INTEREST IN SHARESi1. Identity of the issuer or the underlying issuer of existing shares The Biotech Growthto which voting rights are attached:ii Trust PLC2 Reason for the notification (please tick the appropriate box or boxes):An acquisition or disposal of voting rights NoAn acquisition or disposal of qualifying financial instruments which may result Noin the acquisition of shares already issued to which voting rights are attachedAn acquisition or disposal of instruments with similar economic effect to Noqualifying financial instrumentsAn event changing the breakdown of voting rights NoOther (please specify): Market Purchase of Shares by Company Yes3. Full name of person(s) subject to the notification East Riding of Yorkshireobligation:iii Council4. Full name of shareholder(s) (if different from 3.):iv State Street Nominees Limited5. Date of the transaction and date on which the threshold is 3 October 2014crossed or reached: v6. Date on which issuer notified: 17 October 20147. Threshold(s) that is/are crossed or reached: vi, vii 8.00%8. Notified details:A: Voting rights attached to shares viii, ixClass/type of Situation previous Resulting situation aftershares to the triggering the triggering transaction transactionif possible using Number Number % of votingthe ISIN CODE Number of Number of rights x of Voting of voting Shares Rights shares rights Direct Direct xi Indirect xii Direct Indirect25p Ordinary 5,100,000 5,100,000 5,100,000 5,100,000 N/A 8.00% N/AGB0000385517B: Qualifying Financial InstrumentsResulting situation after the triggering transactionType of financial Expiration Exercise/ Number of voting % of voting instrument date xiii Conversion Period xiv rights that may be rights acquired if the instrument is exercised/ converted. N/A N/A N/A N/A N/AC: Financial Instruments with similar economic effect to Qualifying FinancialInstruments xv, xviResulting situation after the triggering transactionType of financial Exercise Expiration Exercise/ Number of voting % of voting instrument price date xvii Conversion rights instrument rights xix, xx period xviii refers to Nominal Delta N/A N/A N/A N/A N/A N/A N/ATotal (A+B+C) Number of voting rights Percentage of voting rights 5,100,000 8.00%9. Chain of controlled undertakings through which the voting rights and/or thefinancial instruments are effectively held, if applicable: xxiN/AProxy Voting:10. Name of the proxy holder: N/A11. Number of voting rights proxy holder will cease to hold: N/A12. Date on which proxy holder will cease to hold voting rights: N/A13. Additional information: Calculation based on 63,778,516 shares in issue14. Contact name: Joanna Nottingham15. Contact telephone number: 01482 394149