BioSenic SA — Share Issue/Capital Change 2018

Jul 20, 2018

Regulated information 20 July 2018

Information on the total number of voting rights and shares

Gosselies, Belgium, 20 July 2018, 7am CEST – BONE THERAPEUTICS (Euronext Brussels and Paris: BOTHE), the bone cell therapy company addressing high unmet medical needs in orthopaedics and bone diseases, today announces an increase in the total number of voting rights and shares as a result of the issuance of new shares on 11 July 2018 following the conversion of convertible bonds issued on the private placement on 7 March 2018. The following information is published in accordance with Article 15 of the Belgian Law of 2 May 2007 on the publication of major shareholdings in issuers whose shares are admitted to trading on regulated market.

Total amount of share capital on 6 June 2018	EUR 16,337,771
Total number of shares with voting rights on 6 June 2018	7,632,350

Total amount of share capital on 9 July 2018 (1) EUR 11,507,436

Total number of new shares issued on 11 July 2018 100,896

Total amount of share capital on 11 July 2018	EUR 11,659,789
Total number of shares with voting rights on 11 July 2018	7,733,246 (a)
Total number of voting rights (denominator) on 11 July 2018	7,733,246
Total number of attributed warrants	167,300
Total number of convertible bonds outstanding	107
Total number of bond warrants outstanding	4,105
Total number of shares with voting rights that could be created following the exercise of the bond warrants, the conversion of the convertible bonds and the attributed warrants (2)	1,195,741 (b)
Total number of diluted shares with voting rights	8,928,987 (a+b)

(1) The Extraordinary General Shareholders Meeting hold on 9 July 2018, has decided to reduce the issue premiums and the paid-up capital of the Company by absorption of losses carried forward without cancellation of titles. As a result, the share capital was reduced for a total amount of EUR 4,830,335. The par value of Company's share also decreased from EUR 2.14 to EUR 1.51.

(2) Based on the conversion price of EUR 10.2388 (92% of the Volume-Weighted-Averaged-Price of Bone Therapeutics on 11 July 2018)

Regulated information 20 July 2018

About Bone Therapeutics

Bone Therapeutics is a leading cell therapy company addressing high unmet needs in orthopaedics and bone diseases. Based in Gosselies, Belgium, the Company has a broad, diversified portfolio of bone cell therapy products in clinical development across a number of disease areas targeting markets with large unmet medical needs and limited innovation.

Bone Therapeutics' technology is based on a unique, proprietary approach to bone regeneration, which turns undifferentiated stem cells into "osteoblastic", or bone-forming cells. These cells can be administered via a minimally invasive procedure, avoiding the need for invasive surgery.

The Company's primary clinical focus is ALLOB® , an allogeneic "off-the-shelf" cell therapy product derived from stem cells of healthy donors, which is in Phase II studies for the treatment of delayed-union fractures and spinal fusion. The Company also has an autologous bone cell therapy product, PREOB® , obtained from patient's own bone marrow and currently in Phase III development for osteonecrosis of the hip.

Bone Therapeutics' cell therapy products are manufactured to the highest GMP standards and are protected by a rich IP estate covering nine patent families. Further information is available at: www.bonetherapeutics.com.

For further information, please contact:

Bone Therapeutics SA	Tel: +32 (0) 71 12 10 00
Thomas Lienard, Chief Executive Officer Jean-Luc Vandebroek, Chief Financial Officer	investorrelations@bonetherapeutics.com
For Belgium and International Media Enquiries:
Consilium Strategic Communications	Tel: +44 (0) 20 3709 5701
Amber Fennell, Jessica Hodgson, Hendrik Thys and Lindsey Neville	bonetherapeutics@consilium-comms.com
For French Media and Investor Enquiries:
NewCap Investor Relations & Financial Communications	Tel: + 33 (0)1 44 71 94 94
Pierre Laurent, Louis-Victor Delouvrier and Nicolas Merigeau	bone@newcap.eu
For US Media and Investor Enquiries:
Westwicke Partners	Tel: + 1 443 213 0506
John Woolford	john.woolford@westwicke.com

Certain statements, beliefs and opinions in this press release are forward-looking, which reflect the Company or, as appropriate, the Company directors' current expectations and projections about future events. By their nature, forward-looking statements involve a number of risks, uncertainties and assumptions that could cause actual results or events to differ materially from those expressed or implied by the forward-looking statements. These risks, uncertainties and assumptions could adversely affect the outcome and financial effects of the plans and events described herein. A multitude of factors including, but not limited to, changes in demand, competition and technology, can cause actual events, performance or results to differ significantly from any anticipated development. Forward looking statements contained in this press release regarding past trends or activities should not be taken as a representation that such trends or activities will continue in the future. As a result, the Company expressly disclaims any obligation or undertaking to release any update or revisions to any forward-looking statements in this press release as a result of any change in expectations or any change in events, conditions, assumptions or circumstances on which these forward-looking statements are based. Neither the Company nor its advisers or representatives nor any of its subsidiary undertakings or any such person's officers or employees guarantees that the assumptions underlying such forward-looking statements are free from errors nor does either accept any responsibility for the future accuracy of the forwardlooking statements contained in this press release or the actual occurrence of the forecasted developments. You should not place undue reliance on forward-looking statements, which speak only as of the date of this press release.