BIOMARIN PHARMACEUTICAL INC — Director's Dealing 2010

May 6, 2010

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: BIOMARIN PHARMACEUTICAL INC (BMRN)
CIK: 0001048477
Period of Report: 2010-05-03

Reporting Person: FUCHS HENRY J (EVP, Chief Medical Officer)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2010-04-30	Common Stock	A	1442	$13.226	Acquired	21442	Direct
2010-05-03	Common Stock	M	833	$11.05	Acquired	22275	Direct
2010-05-03	Common Stock	S	1442	$22.7892	Disposed	20833	Direct
2010-05-03	Common Stock	S	833	$22.8186	Disposed	20000	Direct

Derivative Transactions

Date	Security	Exercise Price	Code	Shares	A/D	Expiration	Underlying	Ownership
2010-05-03	Stock Option (right to buy)	$11.05	M	833	Acquired	2019-03-01	Common Stock (833)	Direct

Footnotes

F1: Transaction made pursuant to Employee Stock Purchase Plan.

F2: Transaction made pursuant to a Rule 105-1 Trading plan executed on March 3, 2010.

F3: The price in Column 4 is a weighted average price. The prices actually received range from $22.67 to $22.94. The reporting person will provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.

F4: The price in Column 4 is a weighted average price. The prices actually received range from $22.69 to $23.15. The reporting person will provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, information regarding the number of shares sold at each price within the range

F5: Original option grant vests 6/48ths on September 2, 2009 and 1/48th on the 2nd of each month thereafter