BICYCLE THERAPEUTICS PLC — Director's Dealing 2019

May 23, 2019

SEC Form 3 — Initial Statement of Beneficial Ownership

Issuer: BICYCLE THERAPEUTICS Ltd (BCYC)
CIK: 0001761612
Period of Report: 2019-05-22

Reporting Person: Hau Bosun (Director)

Holdings (Derivative)

Security	Exercise Price	Expiration	Underlying	Shares	Ownership
Series B1 Preferred Shares	$		Ordinary Shares (1454412)		Indirect
Series B1 Preferred Shares Warrants	$	2020-05-31	Series B Preferred Shares (139265)		Indirect

Footnotes

F1: Each Series B1 Preferred Share shall automatically convert into Ordinary Shares on a one for 1.429 basis immediately prior to the closing of the Issuer's initial public offering and have no expiration date.

F2: Share numbers give effect to the bonus shares issued to each holder of ordinary shares on the basis of 1.429 bonus shares for each ordinary share in issue, effective on May 13, 2019, which will be effective for the ordinary shares upon their conversion to ordinary shares upon the closing of the Issuer's initial public offering.

F3: The shares are held by Aquila Investments IV, an affiliate of Tybourne Capital Management. The Reporting Person is the Managing Director and Co-Head of Private Equity at Tybourne Capital Management.

F4: The Warrants to Purchase Series B1 Preferred Shares have an exercise price of a nominal value per share. The Warrants are immediately exercisable and expire on March 31, 2020.