BERGENBIO HOSTING VIRTUAL R&D DAY TODAY

Bergen, Norway, 06 November 2020 – BerGenBio ASA (OSE:BGBIO), a clinical-stage biopharmaceutical company developing novel, selective AXL kinase inhibitors for severe unmet medical need, is pleased to announce that it is hosting a Virtual R&D Day today.

The online event will begin at 13.00pmCET (04.00am PST/06.00am CST). Please click here to register.

The event will feature experts from academic institutions across Europe and the US, highlighting the role of AXL kinase as an essential mediator of the biological mechanisms underlying life-threatening diseases, such as cancer, fibrosis and infectious diseases, including COVID-19.

Each presentation will be followed by a Q&A session. Further details on the presentations can be found in the agenda below.

Richard Godfrey, Chief Executive Officer of BerGenBio, commented: "BerGenBio has always been committed to pursuing excellence and innovation in R&D. We remain a world leader in understanding the role and function of AXL biology, and with our collaborators we have demonstrated that AXL is a key driver of immune evasive and drug-resistant metastatic cancer, as well as other aggressive diseases. We are grateful to all our speakers, who during today's event will be providing insights into the latest AXL research, including the clinical benefit seen from bemcentinib."

Agenda

(times inCET)

13:00 Introduction - Richard Godfrey, Chief Executive Officer, BerGenBio

Presentations fromindependentAXLexperts, followed byQ&Asessions led by JimLorens, Chief Scientific Officer and HaniGabra, ChiefMedicalOfficerat BerGenBio

13:10 AXL in AML/MDS Professor Sonja Loges, Director, Department of Personalised Oncology, University Hospital Mannheimand Division of Personalised Medical Oncology, German Cancer Research Center - DKFZ (Heidelberg, Germany)
13:40 AXL in lung cancer Dr MatthewKrebs, Clinical Senior Lecturer in ExperimentalCancer Medicineand HonoraryConsultant inMedicalOncology, The Christie NHS Foundation Trust (Manchester, UK)
14:10 AXL and viruses/COVID-19 Professor Wendy Maury, Professor of Microbiology and Immunology, University ofIowa(Iowa City, USA)
14:40 AXL in fibrosis/IPF Professor CoryHogaboam, Professor ofMedicine, Cedars-SinaiMedicalCenter (LosAngeles, USA)
15:10 Bemcentinib clinical development plan Hani Gabra, Chief Medical Officer, BerGenBio
15:25 Concluding remarks Richard Godfrey, Chief Executive Officer, BerGenBio

For further information, please contact Consilium Strategic Communications at [email protected] or [email protected]

– END –

About AXL

AXL kinase is a cell membrane receptor and an essential mediator of the biological mechanisms underlying life-threatening diseases. In cancer, AXL suppresses the body's immune response to tumours and drives cancer treatment failure across many indications. AXL expression defines a very poor prognosis subgroup in most cancers. AXL inhibitors, therefore, have potential high value at the centre of cancer combination therapy, addressing significant unmet medical needs and multiple high-value market opportunities. Research has also shown that AXL mediates other aggressive diseases.

About Bemcentinib

Bemcentinib (formerly known as BGB324), is a potentially first-in-class selective AXL inhibitor in a broad phase II clinical development programme. Ongoing clinical trials are investigating bemcentinib in multiple solid and haematological tumours, in combination with current and emerging therapies (including immunotherapies, targeted therapies and chemotherapy), and as a single agent. Bemcentinib targets and binds to the intracellular catalytic kinase domain of AXL receptor tyrosine kinase and inhibits its activity. Increase in AXL function has been linked to key mechanisms of drug resistance and immune escape by tumour cells, leading to aggressive metastatic cancers.

About BerGenBioASA

BerGenBio is a clinical-stage biopharmaceutical company focused on developing transformative drugs targeting AXL as a potential cornerstone of therapy for aggressive diseases, including immune-evasive, therapy resistant cancers. The company's proprietary lead candidate, bemcentinib, is a potentially first-in-class selective AXL inhibitor in a broad phase II clinical development programme focused on combination and single agent therapy in lung cancer, leukaemia and COVID-19. A first-in-class functional blocking anti-AXL antibody, tilvestamab, is undergoing phase I clinical testing. In parallel, BerGenBio is developing a companion diagnostic test to identify patient

populations most likely to benefit from bemcentinib: this is expected to facilitate more efficient registration trials supporting a precision

populations most likely to benefit from bemcentinib: this is expected to facilitate more efficient registration trials supporting a precision medicine-based commercialisation strategy.

BerGenBio is based in Bergen, Norway with a subsidiary in Oxford, UK. The company is listed on the Oslo Stock Exchange (ticker: BGBIO). For more information, visit www.bergenbio.com

Contacts

Richard Godfrey CEO, BerGenBio ASA +47 917 86 304

Rune Skeie, CFO, BerGenBio ASA [email protected] +47 917 86 513

International Media Relations

Mary-Jane Elliott, Chris Welsh, Lucy Featherstone, Carina Jurs

Consilium Strategic Communications [email protected] +44 20 3709 5700

Media Relations in Norway

Jan Petter Stiff, Crux Advisers

[email protected] +47 995 13 891

Forward looking statements

This announcement may contain forward-looking statements, which as such are not historical facts, but are based upon various assumptions, many of which are based, in turn, upon further assumptions. These assumptions are inherently subject to significant known and unknown risks, uncertainties and other important factors. Such risks, uncertainties, contingencies and other important factors could cause actual events to differ materially from the expectations expressed or implied in this announcement by such forward-looking statements.

This information is subject to the disclosure requirements pursuant to section 5-12 of the Norwegian Securities TradingAct.

AI Terminal

BerGenBio

3555_rns_2020-11-06_248eb44d-8eb7-43f4-b93f-6aacfd9ec3c5.pdf