BeOne Medicines Ltd. — Director's Dealing 2026

Jan 9, 2026

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: BeOne Medicines Ltd. (ONC)
CIK: 0001651308
Period of Report: 2026-01-07

Reporting Person: Lee Chan Henry (SVP, General Counsel)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2026-01-07	American Depositary Shares	M	202	$194.47	Acquired	202	Direct
2026-01-07	American Depositary Shares	M	266	$213.32	Acquired	468	Direct
2026-01-07	American Depositary Shares	M	196	$159.03	Acquired	664	Direct
2026-01-07	American Depositary Shares	S	664	$331.76	Disposed	0	Direct

Derivative Transactions

Date	Security	Exercise Price	Code	Shares	A/D	Expiration	Underlying	Ownership
2026-01-07	Share Option (Right to Buy)	$14.96	M	2626	Disposed	2032-08-04	Ordinary Shares (2626)	Direct
2026-01-07	Share Option (Right to Buy)	$16.41	M	3458	Disposed	2033-06-14	Ordinary Shares (3458)	Direct
2026-01-07	Share Option (Right to Buy)	$12.23	M	2548	Disposed	2034-06-04	Ordinary Shares (2548)	Direct

Holdings (Non-Derivative)

Security	Shares	Ownership
Ordinary Shares	223106	Direct

Footnotes

F1: Each American Depositary Share represents 13 Ordinary Shares.

F2: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on May 14, 2025.

F3: The number of securities underlying each option and the exercise price therefore are represented in ordinary shares.

F4: These securities vest over a four-year period as follows: 25% on July 29, 2023 with the remaining shares vesting in 36 equal successive monthly installments thereafter, subject to continued service. Unvested securities are subject to accelerated vesting upon certain termination events.

F5: These securities vest over a four-year period as follows: 25% on the first anniversary of June 15, 2023 with the remaining shares vesting in 36 equal successive monthly installments thereafter, subject to continued service. Unvested securities are subject to accelerated vesting upon certain termination events.

F6: These securities vest over a four-year period as follows: 25% on the first anniversary of June 5, 2024 with the remaining shares vesting in 36 equal successive monthly installments thereafter, subject to continued service. Unvested securities are subject to accelerated vesting upon certain termination events.