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BeOne Medicines Ltd. Director's Dealing 2025

Oct 10, 2025

30073_dirs_2025-10-10_93e4bd64-5bac-4c56-9634-217e9b2569db.zip

Director's Dealing

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SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: BeOne Medicines Ltd. (ONC)
CIK: 0001651308
Period of Report: 2025-10-08

Reporting Person: Lee Chan Henry (SVP, General Counsel)

Non-Derivative Transactions

Date Security Code Shares Price A/D Holdings After Ownership
2025-10-08 American Depositary Shares S 1112 $350 Disposed 0 Direct
2025-10-08 American Depositary Shares M 302 $194.47 Acquired 302 Direct
2025-10-08 American Depositary Shares M 8961 $213.32 Acquired 9263 Direct
2025-10-08 American Depositary Shares M 296 $159.03 Acquired 9559 Direct
2025-10-08 American Depositary Shares S 664 $347.82 Disposed 8895 Direct
2025-10-08 American Depositary Shares S 4733 $350.2177 Disposed 4162 Direct
2025-10-08 American Depositary Shares S 4162 $351.1232 Disposed 0 Direct

Derivative Transactions

Date Security Exercise Price Code Shares A/D Expiration Underlying Ownership
2025-10-08 Share Option (Right to Buy) $14.96 M 3926 Disposed 2032-08-04 Ordinary Shares (3926) Direct
2025-10-08 Share Option (Right to Buy) $16.41 M 116493 Disposed 2033-06-14 Ordinary Shares (116493) Direct
2025-10-08 Share Option (Right to Buy) $12.23 M 3848 Disposed 2034-06-04 Ordinary Shares (3848) Direct

Holdings (Non-Derivative)

Security Shares Ownership
Ordinary Shares 223106 Direct

Footnotes

F1: Each American Depositary Share represents 13 Ordinary Shares.

F2: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on May 14, 2025.

F3: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $350.00 to $350.98, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

F4: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $351.00 to $351.53, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

F5: The number of securities underlying each option and the exercise price therefore are represented in ordinary shares.

F6: These securities vest over a four-year period as follows: 25% on July 29, 2023 with the remaining shares vesting in 36 equal successive monthly installments thereafter, subject to continued service. Unvested securities are subject to accelerated vesting upon certain termination events.

F7: These securities vest over a four-year period as follows: 25% on the first anniversary of June 15, 2023 with the remaining shares vesting in 36 equal successive monthly installments thereafter, subject to continued service. Unvested securities are subject to accelerated vesting upon certain termination events.

F8: These securities vest over a four-year period as follows: 25% on the first anniversary of June 5, 2024 with the remaining shares vesting in 36 equal successive monthly installments thereafter, subject to continued service. Unvested securities are subject to accelerated vesting upon certain termination events.