AVECHO BIOTECHNOLOGY LIMITED — Director's Dealing 2021

Sep 9, 2021

Appendix 3Y Change of Director’s Interest Notice

Rule 3.19A.2

Appendix 3Y

Change of Director’s Interest Notice

Information or documents not available now must be given to ASX as soon as available. Information and documents given to ASX become ASX’s property and may be made public.

Introduced 30/09/01 Amended 01/01/11

Name of entity: Avecho Biotechnology Limited ABN 32 056 482 403

We (the entity) give ASX the following information under listing rule 3.19A.2 and as agent for the director for the purposes of section 205G of the Corporations Act.

Name of Director	Gregory Collier
Date of last notice	31 May 2021

Part 1 - Change of director’s relevant interests in securities

In the case of a trust, this includes interests in the trust made available by the responsible entity of the trust

Note: In the case of a company, interests which come within paragraph (i) of the definition of “notifiable interest of a director” should be disclosed in this part.

Direct or indirect interest	Indirect
Nature of indirect interest	Gregory Collier is a Director of Beacon Super Fund Pty
(including registered holder)	Ltd <Beacon Super Fund A/c> and a beneficiary if the
Note: Provide details of the circumstances giving rise to the relevant	fund.
interest.
Date of change	10 September 2021
No. of securities held prior to change	Direct
	5,990,465 unlisted options exercisable at $0.0169 each
	and expiring on 29 November 2024.
	Indirect
	Beacon Super Fund Pty Ltd <Beacon Super Fund A/c>
	2,000,000 Fully Paid Ordinary Shares
	2,250,000 Unlisted Options
	(Gregory Collier is a Director of the entity and a
	beneficiary if the fund).
Class	Unlisted Options expired on 10 September 2021
Number acquired	N/A
Number disposed	2,250,000

• See chapter 19 for defined terms.

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Appendix 3Y Change of Director’s Interest Notice

Value/ConsiderationNote: If consideration is non-cash, provide details and estimated valuation	NIL
No. of securities held after change	Direct5,990,465 unlisted options exercisable at $0.0169 eachand expiring on 29 November 2024.IndirectBeacon Super Fund Pty Ltd <Beacon Super Fund A/c>2,000,000 Fully Paid Ordinary Shares
Nature of changeExample: on-market trade, off-market trade, exercise of options, issue ofsecurities under dividend reinvestment plan, participation in buy-back	The 2,250,000 unlisted options expired on 10September 2021 without being exercised.

Part 2 – Change of director’s interests in contracts

Note: In the case of a company, interests which come within paragraph (ii) of the definition of “notifiable interest of a director” should be disclosed in this part.

Detail of contract	N/A
Nature of interest	N/A
Name of registered holder(if issued securities)	N/A
Date of change	N/A
No. and class of securities to whichinterest related prior to changeNote: Details are only required for a contract in relationto which the interest has changed	N/A
Interest acquired	N/A
Interest disposed	N/A
Value/ConsiderationNote: If consideration is non-cash, provide details and anestimated valuation	N/A
Interest after change	N/A

• See chapter 19 for defined terms.

Appendix 3Y Page 2

01/01/2011

Appendix 3Y Change of Director’s Interest Notice

Part 3 –[+] Closed period

Part 3 –+Closed period
Were the interests in the securities or contracts detailedabove traded during a+closed period where prior writtenclearance was required?	No
If so, was prior written clearance provided to allow the tradeto proceed during this period?	N/A
If prior written clearance was provided, on what date was thisprovided?	N/A

• See chapter 19 for defined terms.

01/01/2011 Appendix 3Y Page 3