AVECHO BIOTECHNOLOGY LIMITED — Director's Dealing 2011

Jul 3, 2011

Appendix 3Y Change of Director’s Interest Notice

Rule 3.19A.2

Appendix 3Y

Change of Director’s Interest Notice

Information or documents not available now must be given to ASX as soon as available. Information and documents given to ASX become ASX’s property and may be made public.

Introduced 30/9/2001.

Name of entity PHOSPHAGENICS LIMITED ABN 32 056 482 403

We (the entity) give ASX the following information under listing rule 3.19A.2 and as agent for the director for the purposes of section 205G of the Corporations Act.

Name of Director JAMES, Stuart Bruce

Date of last notice 30 August 2010 (Appendix 3X)

Part 1 - Change of director’s relevant interests in securities

In the case of a trust, this includes interests in the trust made available by the responsible entity of the trust

Note: In the case of a company, interests which come within paragraph (i) of the definition of “notifiable interest of a director” should be disclosed in this part.

Direct or indirect interest	Refer Annexure “A”
Nature of indirect interest(including registered holder)Note: Provide details of the circumstances giving rise to the relevant interest.	Refer Annexure “A”
Date of change	Refer Annexure “A”
No. of securities held prior to change	Refer Annexure “A”
Class	Refer Annexure “A”
Number acquired	Refer Annexure “A”
Number disposed	Refer Annexure “A”
Value/ConsiderationNote: If consideration is non-cash, provide details and estimated valuation	Refer Annexure “A”
No. of securities held after change	Refer Annexure “A”
Nature of changeExample: on-market trade, off-market trade, exercise of options, issue ofsecurities under dividend reinvestment plan, participation in buy-back	Refer Annexure “A”

• See chapter 19 for defined terms.

Appendix 3Y Page 1

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Appendix 3Y Change of Director’s Interest Notice

Part 2 – Change of director’s interests in contracts

Note: In the case of a company, interests which come within paragraph (ii) of the definition of “notifiable interest of a director” should be disclosed in this part.

Detail of contract Not applicable Nature of interest Name of registered holder (if issued securities) Date of change No. and class of securities to which interest related prior to change Note: Details are only required for a contract in relation to which the interest has changed Interest acquired Interest disposed Value/Consideration Note: If consideration is non-cash, provide details and an estimated valuation Interest after change

Part 3 –[+] Closed period

	Part 3 –+Closed period	Part 3 –+Closed period	Part 3 –+Closed period	Part 3 –+Closed period	Part 3 –+Closed period
	Were the interests in the securities or contracts					No
	detaiwher	led above traded during a+closed peri			od
		e prior written c	learance wa	s required?
	If soallow	, was prior wthe trade to pr	ritten clearoceed during	ance providedthis period?	to	NOT APPL	ICABLE
	If pr	ior written clea	rance was p	rovided, on wh	at	NOT APPL	ICABLE
	date was this provided?

poh\asx\3y sbj 04 07 11

• See chapter 19 for defined terms.

Appendix 3Y Page 2

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Appendix 3Y Change of Director’s Interest Notice

Appendix 3Y Change of Director’s Interest Notice Mr S B James

This is the Annexure marked “A” of one page referred to in the Appendix 3Y (Change Director’s Interest Notice) of Stuart Bruce JAMES.

Current Previous Appendix 3Y Appendix 3X A Shares NIL NIL B Unquoted Options Self March 2013 Options 2,400,000 NIL Movements: A Shares – no change B Unquoted Options By way of an off-market transaction on 30 June 2011. Mr Mullins acquired 2,400,000 March 2012 unquoted options at a consideration of 3.5 cents an option. The March 2013 option exercise price is 14.2 cents.

Comment:

Mr James is the legal and beneficial owner of the 2,400,000 unquoted options registered in his name.

• See chapter 19 for defined terms.

Appendix 3Y Page 3

11/3/2002