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Avantor, Inc. Proxy Solicitation & Information Statement 2026

Mar 27, 2026

30731_psi_2026-03-27_12ff0f0c-17a2-4f52-be2d-256f6a06a82a.zip

Proxy Solicitation & Information Statement

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UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

SCHEDULE 14A

Proxy Statement Pursuant to Section 14(a) of the

Securities Exchange Act of 1934

Filed by the Registrant Filed by a Party other than the Registrant ☐

Check the appropriate box:

Preliminary Proxy Statement
Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2))
Definitive Proxy Statement
Definitive Additional Materials
Soliciting Material Pursuant under §240.14a-12

AVANTOR, INC.

(Name of Registrant as Specified In Its Charter)

(Name of Person(s) Filing Proxy Statement, if Other Than the Registrant)

Payment of Filing Fee (Check all boxes that apply):

No fee required
Fee paid previously with preliminary materials
Fee computed on table in exhibit required by Item 25(b) per Exchange Act Rules 14a-6(i)(1) and 0-11

2026 Proxy Statement

and Notice of Annual Meeting of Stockholders

Our Mission We set science in motion to create a better world.

Our Vision From discovery to delivery, we are a trusted global provider of mission-critical products and services to customers and suppliers in the life sciences, education, government, advanced technologies and applied materials industries.

Our Values Our core set of principles that guide and focus our strategy are our iCARE values:

ACCOUNTABILITY
We hold ourselves accountable for delivering on our promises to our customers, suppliers, shareholders and colleagues to achieve our shared goals. This includes our commitment to meeting the evolving needs of our customers, suppliers, associates, communities and the environment.
RESPECT
We work to build an inclusive culture by seeking to understand each other’s experiences and celebrating our diverse backgrounds. We treat others with dignity and operate with the highest level of integrity. Whether working with internal or external partners, we act as one team and always assume others have good intent.
EXCELLENCE
We never settle for the status quo. We strive to achieve the highest levels of safety, quality, and service. Our passion for continuous improvement is embodied by every employee, the results we achieve together, and the support we provide to our customers. We do our best when we welcome diverse perspectives and work collaboratively to find solutions.
INNOVATION
We know that the best ideas come from the collaboration of diverse perspectives. We empower all employees to explore and contribute ideas that elevate our product and service solutions. We welcome feedback that challenges our thinking and helps us grow. By collaborating with our industry partners, we improve scientific outcomes.
CUSTOMER CENTRIC
Everything we do begins with actively listening and collaborating with our internal and external customers. By understanding their challenges and aspirations, we proactively identify solutions that address their current and future needs.

In 2025, the board of directors took aggressive action to enhance governance, strengthen the business, and build stockholder trust.” GREGORY SUMME Chairman Message from our Chairman Dear Stockholders, We are pleased to invite our stockholders to our 2026 Annual Meeting of Shareholders on May 7, 2026, at 11:00 a.m. Eastern Time, where we look forward to sharing more about Avantor’s recent progress. We appreciate your vote on the matters set forth in our Proxy Statement. In 2025, the Board of Directors took aggressive action to enhance governance, strengthen the business, and build stockholder trust. We were pleased to appoint Emmanuel Ligner as our Chief Executive Officer in August 2025. Emmanuel is a highly energetic and experienced leader in the life sciences industry with a strong track record of value creation. Emmanuel and his leadership team have launched a comprehensive improvement program, labeled Revival, and we are encouraged by the early results. Since the launch of the Revival program in October, Avantor has taken significant steps to improve our go-to-market strategy, including relaunching VWR, Avantor’s leading distribution channel, and ensuring each of our two primary businesses compete in the market with distinct and fit-for-purpose strategies. Avantor is well positioned to build on this early progress, as we advance the Revival program and continue to serve our more than 300,000 customer locations. We also strengthened our Board in the fourth quarter of 2025 with the addition of three very talented new directors – Simon Dingemans, Greg Lucier, and Sanjeev Mehra. Each brings valuable leadership experience in healthcare, global operations, talent management, and capital allocation and will help support Avantor’s Revival plan. Our Board is committed to holding itself and Avantor leadership accountable, and we are confident in our ability to deliver greater value for our stockholders. On behalf of the Board, our management team, and thousands of associates around the world, thank you for your support and for your investment in Avantor.

1

Notice of 2026 Annual Meeting of Stockholders

VIRTUAL STOCKHOLDERS MEETING

Items of Business Board Recommendations
1 To elect the nine directors named in this Proxy Statement to serve a one-year term expiring at the 2027 annual meeting of stockholders; “FOR” each of the nominees Page 11
2 To approve, on an advisory basis, the compensation of our named executive officers; “FOR” Page 42
3 To determine, on an advisory basis, the frequency of future advisory votes on executive compensation; “ONE-YEAR” Page 43
4 To ratify the appointment of Deloitte & Touche LLP as the Company’s independent registered public accounting firm for 2026; and “FOR” Page 83
5 To transact such other business as may properly come before the meeting or any adjournment or postponement thereof.

The Annual Meeting of Stockholders (“Annual Meeting”) of Avantor, Inc. (“Avantor” or the

“Company”) will be held on Thursday, May 7, 2026, at 11:00 a.m. Eastern Time. This year’s

Annual Meeting will be completely virtual, conducted via live audio webcast on the Internet.

Stockholders will be able to listen to and participate in the meeting online, vote their shares

electronically, and submit questions during the meeting by visiting

www.virtualshareholdermeeting.com/AVTR2026 . You will need the 16-digit control

number included on your Notice of Internet Availability or proxy card to gain access to the

meeting. Stockholders of record of Avantor common stock at the close of business on

March 13, 2026 will be able to vote online during the meeting. You have received these

proxy materials because our Board of Directors is soliciting your proxy to vote your shares

at the 2026 Annual Meeting.

For more information on how to attend the meeting and vote, see “Questions and Answers

About the Meeting and Voting” in the Proxy Statement.

On behalf of Avantor’s Board of Directors,

CLAUDIUS O. SOKENU

Executive Vice President, Chief Legal and Compliance Officer and Corporate Secretary

This Notice of 2026 Annual Meeting and Proxy Statement, together with our Annual Report

on Form 10-K for the fiscal year ended December 31, 2025, were first made available to

stockholders on or about March 27, 2026.

Important Notice Regarding the Availability of Proxy Materials for the Stockholder

Meeting to Be Held on May 7, 2026: This Notice and Proxy Statement and our Annual

Report are available free of charge at www.proxyvote.com, a site that does not have

“cookies” that identify visitors to the site.

Please refer to the enclosed proxy materials or the information forwarded by your bank,

broker, trustee or other intermediary to see which voting methods are available to you.

Date and Time Thursday, May 7, 2026 11:00 a.m. Eastern Time
Location Online Virtual Meeting at www.virtualshareholderme eting.com/AVTR2026
Who Can Vote Stockholders of record of Avantor common stock at the close of business on March 13, 2026

HOW TO CAST YOUR VOTE Your vote is important! Please cast your vote and play a part in the future of Avantor. You may vote using any one of the following methods. You will need your 16-digit control number from your Notice of Internet Availability or proxy card.

Internet before the Annual Meeting at www.proxyvote.com
Phone call 1-800-690-6903 toll-free from the U.S. or Canada
Mail return the signed proxy card
Virtual meeting only if you are an eligible stockholder or beneficial owner and have registered and obtained a legal proxy

Your vote is important. We

encourage you to vote by proxy in

advance of the Annual Meeting.

Voting in advance will not affect

your right to attend the Annual

Meeting. Even if you plan to

attend via live audio webcast,

we hope you will vote as soon

as possible.

2 2026 Proxy Statement

Table of Contents

Proxy Summary 3
Proposal 1 Election of Directors 11
Director Nomination Process 12
Director Skills Matrix 13
Director Nominees to Serve for a One-Year Term Expiring in 2027 14
Corporate Governance 20
Board and Governance Highlights 20
The Structure and Role of the Board of Directors 21
Committees of the Board 24
Board Policies and Practices 29
Stockholder Engagement Program 31
Governance Documents 32
Communications with Directors 33
Certain Relationships and Related Person Transactions 33
Commitment to Sustainability 34
Director Compensation 37
Stock Ownership Guidelines 38
Stock Ownership Information 39
Avantor Stock Ownership 39
Delinquent Section 16(a) Reports 41
Proposal 2 Advisory Approval of Named Executive Officer Compensation 42
Proposal 3 Advisory Vote on the Frequency of Future Advisory Votes on Executive Compensation 43
Executive Compensation 44
Compensation Discussion and Analysis 44
Executive Summary 45
Compensation Philosophy & Objectives — How We Make Compensation Decisions 49
Elements of Compensation — What We Paid and Why 51
Compensation and Human Resources Committee Report 65
Executive Compensation Tables 66
Summary Compensation Table 66
CEO Pay Ratio 77
Equity Compensation Plans 78
Pay Versus Performance Disclosure 79
Proposal 4 Ratification of Appointment of Independent Registered Public Accounting Firm 83
Report of the Audit and Finance Committee 84
Audit and Non-audit Fees 85
Pre-approval Policy for Auditor Services 85
Questions and Answers About the Meeting and Voting 86
Other Business 91
Appendix A: Non-GAAP Financial Measurements 92

FORWARD-LOOKING AND CAUTIONARY STATEMENTS

Certain of the statements contained in this Proxy Statement are forward-

looking statements within the meaning of Section 27A of the Securities

Act of 1933, as amended (the "Securities Act") and Section 21E of the

Securities Exchange Act of 1934, as amended (the “Exchange Act”) and

are subject to the safe harbor created thereby under the Private

Securities Litigation Reform Act of 1995. Forward-looking statements

discuss our current expectations and projections relating to our financial

condition, results of operations, plans, objectives, future performance and

business. These statements may be preceded by, followed by or include

the words “aim,” “anticipate,” “assumption,” “believe,” “continue,”

“estimate,” “expect,” “forecast,” “goal,” “guidance,” “intend,” “likely,” “long-

term,” “near-term,” “objective,” “opportunity,” “outlook,” “plan,” “potential,”

“project,” “projection,” “prospects,” “seek,” “target,” “trend,” “can,” “could,”

“may,” “should,” “would,” “will,” the negatives thereof and other words and

terms of similar meaning.

We have based these forward-looking statements on our current

expectations and projections about future events. Although we believe

that our assumptions made in connection with the forward-looking

statements are reasonable, we cannot assure you that the assumptions

and expectations will prove to be correct. Factors that could contribute to

these risks, uncertainties and assumptions include, but are not limited to,

the factors described in “Risk Factors” in our most recent Annual Report

on Form 10-K, as such risk factors may be updated from time to time in

our periodic filings with the SEC. All forward-looking statements speak

only as of the date of this Proxy Statement. We undertake no obligations

to update or revise publicly any forward-looking statements, whether as a

result of new information, future events or otherwise other than as

required under the federal securities laws.

Web links throughout this document are provided for convenience only,

and the content on the referenced website does not constitute a part of

this Proxy Statement.

3

Proxy Summary

This summary highlights information contained elsewhere in this Proxy Statement. This summary does not contain all of

the information that you should consider. You should read the entire Proxy Statement and Avantor’s 2025 Annual Report

on Form 10-K before voting.

2026 Annual Meeting of Stockholders

Time and Date: 11:00 a.m. Eastern Time, May 7, 2026 Location: Online “virtual meeting” at www.virtualshareholdermeeting.com/ AVTR2026 . Stockholders will need to enter their 16-digit control number included on their Notice of Internet Availability or proxy card in order to participate.
Record Date: March 13, 2026 Voting: Stockholders as of the record date are entitled to vote. Each share of common stock is entitled to one vote for each director nominee and one vote for each of the other proposals to be voted on.

Meeting Agenda and Voting Recommendations

Proposals Board vote recommendation Page reference (for more detail)
1 Election of Each of the Nine Directors Named in this Proxy Statement to Serve a One-Year Term Expiring at the 2027 annual meeting of stockholders FOR each Nominee Page 11
2 Advisory Approval of Named Executive Officer Compensation FOR Page 42
3 Advisory Vote on the Frequency of Future Advisory Votes on Executive Compensation ONE YEAR Page 43
4 Ratification of Appointment of Deloitte & Touche LLP as the Company’s Independent Registered Public Accounting Firm for 2026 FOR Page 83

4 2026 Proxy Statement

Proxy Summary

Leadership Transitions

In April 2025, Avantor determined to end the employment of Mr. Stubblefield and the parties agreed, pursuant to a

transition agreement dated April 24, 2025 (the “Transition Agreement”), to a transition period wherein Mr. Stubblefield

would remain employed as the Director, President and Chief Executive Officer until a successor was appointed and

following such appointment, Mr. Stubblefield would remain a non-executive employee advisor until February 28, 2026, to

facilitate a smooth transition. Following a comprehensive search led by an independent executive search firm, and with

Board approval, the Board appointed Emmanuel Ligner as President and Chief Executive Officer and Director effective

August 2025.

The Company also announced planned changes in the leadership of the Board. Jonathan Peacock, the Chairman of the

Board, notified the Company of his intention to retire from the Board effective December 31, 2025. In anticipation of Mr.

Peacock’s retirement, the Board appointed Gregory Summe to serve as Chairman of the Board, effective January 1, 2026.

In addition, the Board continued to strengthen its composition with the appointment of three new directors in addition to

Mr. Ligner. Gregory Lucier joined the Board in October 2025, followed by Sanjeev Mehra in December 2025, and Simon

Dingemans in January 2026. Each of these directors brings significant leadership experience and a variety of expertise to

support the Company’s long‑term strategic objectives.

Emmanuel Ligner New President and CEO and Director Gregory L. Summe New Chairman of the Board Simon Dingemans New Director Gregory T. Lucier New Director Sanjeev Mehra New Director

Performance Overview

From discovery to delivery, Avantor is a trusted global provider of mission-critical products and services to customers and

suppliers in the life sciences, education, government, advanced technologies and applied materials industries. We are

proud of the critical role Avantor plays in enabling scientific breakthroughs, working side by side with scientists to address

some of society’s greatest challenges and opportunities.

Adjusted EPS* $0.90
2025 Financial Highlights
Adjusted EBITDA* $1.07B Free Cash Flow* $496M
  • For information about these non-GAAP financial measurements, including reconciliations to the most directly

comparable GAAP-based financial measurements, see “Appendix A - Non-GAAP Financial Measurements.”

5

Proxy Summary

Business Review

Under Mr. Ligner’s leadership, we launched Avantor Revival, a comprehensive strategy to strengthen the foundation of our

business, make the company more competitive in the marketplace, and, ultimately, allow us to deliver more value to our

customers and shareholders.

Avantor Revival Five Focus Areas

Evolve go to market strategy: Optimize our portfolio:
One of the first and most visible steps we took was to relaunch VWR as our distribution brand. This product- agnostic channel provides millions of essential laboratory products to hundreds of thousands of customers around the globe. The VWR brand has a strong legacy, dating back almost 175 years, and reviving the brand allows us to capitalize on the longstanding goodwill VWR has built with customers around the world. We have also made significant progress enhancing our e-commerce platform with the goal of making it easier for customers to both find the products they need and buy them from us. One of the many strengths of Avantor is the breadth of our offerings. We support the end-to-end needs of the scientific community and serve a variety of end markets. Across our portfolio, we have leading businesses, including VWR, NuSil, Masterflex and J.T.Baker. We also have businesses that may not be as well positioned or advantaged, which is why we are scrutinizing our current portfolio to determine which businesses have the desired position, profitability, and growth profile, and which may not be core to Avantor and our future strategic direction.
Strategically invest in our manufacturing and supply chain organization: Simplify how we work:
Avantor’s global manufacturing footprint includes six CGMP facilities where we produce chemicals to support a broad range of life science applications, from biotechnology and biopharmaceuticals to diagnostics and research, spanning early-stage R&D through to full-scale production. We also have a best-in-class distribution network enabled by our almost 40 distribution centers across the globe. We are investing in our infrastructure to enhance our ability to meet production requirements and improve reliability and efficiency. A core component of the Revival plan is simplifying our operating processes to remove barriers that prevent us from executing efficiently. Not only will this make us faster, easier to work with and more agile, we expect that it will unlock cost savings. We are pushing decision making out to the markets and empowering the teams closest to our customers to act with more urgency and conviction. We are also investing in manufacturing digitization to increase operational efficiency, production agility and quality.
Strengthen our talent and improve accountability:
Over 13,500 Avantor associates across the globe work tirelessly to support our mission to set science in motion to create a better world. We have and will continue to add world class talent to our team. In 2025 we hired a new Chief Operating Officer to lead our manufacturing and supply chain operations. We also created a new Chief Digital Officer role to strengthen our digital commerce capabilities and an elevated Head of Quality and Regulatory role, responsible for safeguarding patient safety, ensuring regulatory compliance and driving operational integrity across our global business. We remain committed to attracting and developing the best talent in the business.

Business Evolution

With Revival as our strategic guide, we continue to transform the way we run the company, including the re-

segmentation of our operating units to provide sharper positioning and better alignment with customer needs.

6 2026 Proxy Statement

Proxy Summary

Each segment is anchored by powerful, leading brands that are synonymous with attributes such as quality

and reliability.

Our Laboratory Solutions Segment is now VWR Distribution and Services Our Bioscience Production Segment is now Bioscience and Medtech Products

Our Laboratory Solutions Segment is now VWR Distribution and Services. The guiding principle for the VWR Distribution

and Services segment is a product agnostic channel, primarily composed of third-party content. Over 90% of this segment

is our channel business with the balance being our services offerings. This business builds on VWR’s nearly 175-year

legacy as a trusted distribution engine powering scientific innovation across the globe.

Our Bioscience Production Segment is now Bioscience and Medtech Products. This segment is a

channel-agnostic product business, inclusive of our bioprocessing, research and specialty chemicals, robust fluid handling

portfolio and our ultra-high purity silicon franchise. This business offers a diversified portfolio from leading brands,

including J.T.Baker which offers a broad range of chemicals used in biopharmaceutical manufacturing, laboratory research

and diagnostics applications; Masterflex which delivers unrivaled fluid handling scalability, flexibility, and efficiency; and

NuSil, a global leader in high-purity, specialty silicone technology.

Stockholder Engagement Highlights

We believe that direct dialogue with stockholders is important to our long-term

success. We regularly interact with our stockholders through our stockholder

engagement program that reaches current stockholders, market participants

and potential investors in a variety of forums. Engagements are led by

members of our senior management team and have also included participation

from members of our Board. In 2025, we engaged with investors representing

74% of shares outstanding. Our discussions with stockholders covered several

topics, including financial performance and capital allocation priorities, strategic

and operational priorities, key leadership appointments, Board composition and

refreshment, our CEO and Board Chairman transitions, executive

compensation practices and sustainability priorities and progress.

WE ENGAGED WITH INVESTORS REPRESENTING
74% of shares outstanding in 2025

For more information on our approach to stockholder engagement, see “Corporate Governance — Stockholder

Engagement Program.” For more information on our stockholder engagement efforts with respect to last year’s say-on-

pay vote and executive compensation, see “Executive Compensation — Compensation Discussion and Analysis — 2025

Say-On-Pay Vote and Stockholder Engagement.”

7

Proxy Summary

Corporate Governance Highlights

Avantor is committed to good corporate governance, which we believe is important to the success of our business and in

advancing stockholder interests.

Corporate Governance Highlights include:

Robust Board Oversight and Structure Close Alignment with Shareholder Interests
• Separate Chairman and CEO roles • 8 out of 9 Director Nominees are independent • Regular Executive Sessions of Independent Directors • Risk oversight by the Full Board and its Committees • No classified board • Annual Elections for Board Members • Proxy access for stockholders • Majority voting standard in uncontested elections of directors and a resignation policy applicable to incumbent directors not receiving the requisite vote • 20% threshold for stockholders to call a special meeting
Evaluations Related to the Board and Committees Safeguards
• Annual Board and Committee Self-Evaluations • Policies Prohibiting Short Sales, Hedging, Margin Accounts and Pledging of Stock by Directors and Officers

For more information on our corporate governance practices, see “Corporate Governance.”

8 2026 Proxy Statement

Proxy Summary

Board Nominees

Avantor’s Board of Directors currently has twelve members. Juan Andres, John Carethers and Lan Kang, current

members of the Board of Directors, will not stand for re-election at the Annual Meeting in order to focus on other business

and personal interests. In connection with the decisions of Messrs. Andres and Carethers and Ms. Kang to not stand for

reelection, the Board has determined to reduce its size from twelve members to nine. All director nominees currently serve

on the Board and will be elected for a one-year term expiring at the next annual meeting of stockholders.

The following table provides summary information about each director nominee standing for re-election at the Annual

Meeting.

Name Age Director Since Principal Occupation Independent Committee Memberships
Simon Dingemans 62 2026 Former Chief Financial Officer of GlaxoSmithKline plc Yes Audit & Finance
Emmanuel Ligner 55 2025 President and Chief Executive Officer, Avantor, Inc. No
Gregory Lucier 61 2025 Executive Chairman and CEO of Corza Medical Yes Compensation & Human Resources Nominating & Governance (Chair)
Dame Louise Makin 65 2024 Chair, Halma plc Yes Audit & Finance Nominating & Governance
Joseph Massaro 56 2021 Vice Chair and President, Engineered Components, Aptiv PLC Yes Audit & Finance (Chair) Nominating & Governance
Sanjeev Mehra 67 2025 Co-Founder and Managing Partner, Periphas Capital LP Yes Audit & Finance Compensation & Human Resources
Mala Murthy 62 2021 Chief Financial Officer, TriNet Group, Inc. Yes Audit & Finance
Michael Severino, M.D. 60 2020 Chief Executive Officer, Tessera Therapeutics Yes Compensation & Human Resources (Chair) Science & Technology
Gregory Summe Chairman 68 2020 Managing Partner, Glen Capital Partners Yes Compensation & Human Resources Nominating & Governance

INDEPENDENCE

8 /9 Independent

TENURE

< 1 year
1-5 years
> 5 years

AGE

50-59 years
60-69 years

9

Proxy Summary

Executive Compensation Highlights

Our Compensation Objectives

Avantor’s executive compensation is designed to support the longevity and stability of the Company by driving long-term

business outcomes and promoting strong governance practices. This is done by linking individual pay with Avantor’s

performance on a diverse set of measures, including financial and corporate strategic goals. In 2025, these goals included

employee inclusion index and reduction in greenhouse gas emissions.

Our executive compensation practices include the following, each of which the Compensation and Human Resources

Committee believes reinforces our executive compensation objectives:

WHAT WE HAVE
Significant percentage of target annual compensation delivered in the form of variable compensation tied to performance Long-term objectives aligned with the creation of stockholder value Market comparison of executive compensation against a relevant peer group Robust stock ownership guidelines Use of an independent compensation consultant reporting directly to the Compensation and Human Resources Committee Compensation recovery “clawback” policy for our annual cash-based incentive and all equity-based long-term incentive programs, including time- based equity awards An additional Dodd-Frank compliant compensation recovery “clawback” policy applicable to current and former executive officers in the event of a financial restatement Regular engagement with our stockholders and implementation of enhancements based on feedback received ‘Double-trigger’ change-in-control vesting provision
WHAT WE DON’T HAVE
Hedging or short sales of Company stock, or pledging of Company stock Option grants below 100% fair market value Excessive cash severance benefits upon a change of control Excessive perquisites or benefits to executives Repricing of underwater stock options under our long-term incentive plan Tax gross-ups of perquisites or 280G excise taxes (except as applicable to management employees generally in connection with relocation or expatriate assignments) Payment of unearned dividends prior to vesting

10 2026 Proxy Statement

Proxy Summary

Our Compensation Mix

A large portion of compensation for our senior executives is variable and covers annual and multi-year performance

periods. Long-term awards in the form of performance stock units, stock options, and restricted stock units are designed

to align executives’ interests with Avantor’s long-term performance.

CEO (1) AVERAGE OTHER NEOs (2)

(1) Reflects annualized base salary, target short-term incentive and 2026 target long-term incentive for Emmanuel Ligner.

(2) Reflects average annualized base salary, target short-term incentive and target long-term incentive for named executive officers

employed on December 31, 2025.

11

PROPOSAL NO. 1 Election of Directors
The Board of Directors unanimously recommends a vote “ FOR ” the election of each of the directors listed below to the Board for a one-year term expiring at the 2027 annual meeting of stockholders.

At this Annual Meeting, all directors will be elected for a one-year term that will expire at our next annual meeting of

stockholders. Our Board currently has twelve members. Nine of our directors are standing for election at the Annual

Meeting. Juan Andres, a director since 2019, John Carethers, a director since 2021, and Lan Kang, a director since 2021,

will not stand for re-election in order to focus on other business and personal interests.

The biographies below describe the business experience of each director nominee standing for re-election. We also

identify the specific experience and qualifications of each nominee that strengthen the Board of Directors as a group. In

considering the director nominees for election at the Annual Meeting, the Nominating and Governance Committee

assessed each nominee’s contributions in the context of the Board evaluation process and other perceived needs of the

Board. All of this information was taken into account when the Board considered whether the nominees have the

experience, qualifications, attributes and skills, taken as a whole, to enable the Board to satisfy its oversight

responsibilities effectively in light of our business and strategy.

The Board expects that each of the nominees listed below will be available to serve as a director. However, if one or more

of the nominees is not available to serve, the individuals named in the form of proxy will vote for any substitute nominee(s)

the Board may recommend. Alternatively, the Board may reduce its size.

A nominee must receive a majority of the votes cast with respect to that nominee’s election at the meeting at which a

quorum is present by the holders of capital stock entitled to vote in the election to be elected, which means that the

number of votes cast “for” a nominee’s election must exceed the number of votes cast “against” that nominee’s election.

Our bylaws require that each incumbent director nominee submit an irrevocable letter of resignation as director that

becomes effective if he or she fails to receive a majority of the votes cast in an uncontested election and the Board

accepts the resignation. If any incumbent director nominee fails to receive a majority of the votes cast in an uncontested

election at which a quorum is present, the Nominating and Governance Committee will make a recommendation to the

Board on whether to accept or reject such resignation.

12 2026 Proxy Statement

Proposal 1 Election of Directors

Director Nomination Process

Assess Composition and Determine Priorities

The Nominating and Governance Committee considers the skills and experience outlined in our Director Skills Matrix to

determine its priorities in seeking out new director candidates for the continuation of healthy Board refreshment.

Solicit and Source a Broad Pool of Candidates

Working with the Chairman of the Board, the Nominating and Governance Committee seeks out a wide-ranging pool of

candidates using multiple sources, including engaging third-party search firms and receiving input from directors and

stakeholders. Our Corporate Governance Guidelines provide that, as part of our search process, the Nominating and

Governance Committee actively considers individuals who reflect a broad range of experiences, perspectives and

backgrounds.

Evaluate and Select Candidates

The Nominating and Governance Committee evaluates candidates based on its set priorities and director qualification

standards. At a minimum, the Nominating and Governance Committee considers each candidate’s strength of character,

judgment, familiarity with the Company’s business and industry, independence of thought, and ability to work collegially

with the other members of the Board. The Nominating and Governance Committee also may consider a candidate’s

existing commitments to other businesses, potential conflicts of interest with other pursuits, legal considerations such as

antitrust issues, corporate governance background, various and relevant career experience, relevant technical skills,

relevant business or government acumen, financial and accounting background, executive compensation background,

and the size, composition and combined expertise of the existing Board. Once candidates are selected, the Nominating

and Governance Committee makes recommendations to the Board. In addition, stockholders may nominate directors for

election at the Company’s annual stockholders meeting by following the provisions set forth in the Company’s bylaws.

2025 Board Refreshment

In 2025, the Board, led by the Nominating and Governance Committee, appointed Gregory Lucier, Sanjeev Mehra and

Simon Dingemans as new independent directors and Emmanuel Ligner as a management director. Together, Messrs.

Dingemans, Lucier and Mehra bring deep global leadership across healthcare, life sciences, finance, strategy, and capital

allocation, providing the Board with a powerful combination of operational insight, innovation expertise, and disciplined

financial oversight that supports long-term growth and stockholder value.

Stockholder Recommendations and Proxy Access

The Nominating and Governance Committee welcomes recommendations from stockholders regarding prospective Board

members. These candidates are evaluated on a substantially similar basis as nominees derived from other sources.

Our bylaws include a proxy access provision that allows an eligible stockholder or group of up to 20 eligible stockholders,

owning at least 3% of the Company’s outstanding common shares continuously for at least three years, to include in the

Company’s proxy materials for an annual meeting of stockholders a number of director nominees up to the greater of two

directors or 20% of the Board of Directors, provided the stockholders and nominees satisfy prescribed requirements.

13

Proposal 1 Election of Directors

Director Skills Matrix

Our directors possess relevant skills and experience that contribute to a well-functioning Board that effectively oversees

our strategy and management.

Director Nominee Skills and Experience Dingemans Ligner Lucier Makin Massaro Mehra Murthy Severino Summe
Board leadership As a Board chair, lead director or committee chair equips directors to lead our Board and its committees
Financial expertise As a finance executive or CEO brings valuable experience to the Board and our management team
M&A/transactional experience Helps the Board and our management team assess acquisition opportunities consistent with our strategic priorities and long-range plans
Operations experience Increases the Board’s understanding of our manufacturing operations, services opportunities and distribution footprint
Regulatory/legal/public policy experience Helps the Board assess and respond to an evolving business and healthcare regulatory environment
International experience Brings critical insights into the opportunities and risks of our international businesses
Digital/cybersecurity experience Increases the Board’s awareness of advances in technology, cybersecurity and information systems management
Research, development & innovation experience Helps the Board and our management team assess new product design and development opportunities consistent with our strategic priorities
Human capital management experience Helps oversee our talent/leadership development, employee compensation and employee engagement efforts
Distribution & logistics Brings critical insights into supply chain, fulfillment and transportation strategies for efficient product delivery

14 2026 Proxy Statement

Proposal 1 Election of Directors

Director Nominees to Serve for a One-Year Term

Expiring in 2027

Former Chief Financial Officer at GlaxoSmithKline plc
EXPERIENCE The Carlyle Group, a leading global investment firm (2020-2024) • Managing Director and Senior Advisor GlaxoSmithKline plc, a global biopharmaceutical company (2011 – 2019) • Chief Financial Officer Goldman Sachs International, a global investment banking, securities and investment management firm (1995-2010) • Partner and Managing Director EDUCATION • Master’s Degree in Geography from University of Oxford VALUE TO OUR BOARD Mr. Dingemans brings extensive leadership experience across global healthcare and financial institutions, as well as experience in finance, strategy, capital allocation and organizational transformation (including qualification as an audit committee financial expert). OTHER PUBLIC COMPANY BOARDS • Vodafone Group Plc (2025-present) • Audit Committee Chair • WPP Plc (2022-present)
COMMITTEES Audit & Finance SKILLS

INDEPENDENT

Board leadership Operations experience Digital/cybersecurity experience
LEGEND Financial expertise Regulatory/legal/public policy experience Research, development & innovation
M&A/transactional experience International experience Human capital management experience

15

Proposal 1 Election of Directors

Chief Executive Officer of Avantor, Inc.
EXPERIENCE Avantor, Inc. (2025-Present) • Chief Executive Officer Cerba Healthcare, an international clinical pathology provider, a provider of medical lab testing (2024-2025) • Chief Executive Officer Cytiva, a global life sciences company (2020-2024) • President & CEO GE Life Sciences, a global life sciences company (2017-2020) • Chief Executive Officer and President, 2017 through 2020 EDUCATION • Licence and Maitrise in Commerce from Université de Savoie in France VALUE TO OUR BOARD Mr. Ligner brings over 30 years of strategic and operational leadership experience at large-scale, global, life sciences companies. As CEO of Avantor, he provides a deep understanding of global operations and commercial strategy, which contributes to the Board’s understanding of the Company’s capital allocation, innovation and long-term growth initiatives. OTHER PUBLIC COMPANY BOARDS None
COMMITTEES None SKILLS
Founder, Executive Chairman and CEO of Corza Medical
EXPERIENCE Corza Medical, a leading global manufacturer of surgical technologies and medical device components • Chief Executive Officer, Executive Chairman and Founder (2021-present) NuVasive, a technology leader in minimally invasive spine and orthopedic surgery • Chairman, (2015 - 2021) • Chief Executive Officer, (2015 - 2018) Life Technologies Corporation (2003-2014) • Chairman and Chief Executive Officer General Electric (1994-2003) • President of Medical Information Technologies at GE Healthcare, a $9 billion global leader in medical imaging and technology, 2000 through 2003 • Variety of leadership roles EDUCATION • MBA from Harvard Business School • Bachelor’s Degree in Industrial Engineering from Pennsylvania State University VALUE TO OUR BOARD Mr. Lucier brings over 30 years of life sciences industry experience, with a track record of driving sustainable shareholder value growth and innovation across numerous healthcare companies. His insight into successful R&D initiatives, technological innovations and capital expansion strategies enhances the Board’s oversight of Avantor’s profitability-focused segments. OTHER PUBLIC COMPANY BOARDS • Maravai Lifescience (2020-present) • Dentsply Sirona (2019-present)
COMMITTEES Nominating & Governance Compensation & Human Resources SKILLS

INDEPENDENT

16 2026 Proxy Statement

Proposal 1 Election of Directors

Non-Executive Chair of the Halma Plc Board of Directors
EXPERIENCE BTG Plc, a leading interventional medicine business (2004-2019) • Chief Executive Officer Baxter Healthcare, a global medical technology company (2000-2004) • President of Biopharmaceuticals Europe St. John’s College, Cambridge (2015-present) • Honorary Fellow Order of the British Empire (2014) • Dame Commander EDUCATION • Master’s Degree in Natural Sciences and a Ph.D. in Material Sciences from the University of Cambridge • MBA from The Open University in Milton Keynes, England VALUE TO OUR BOARD The Board benefits from Dame Louise's senior leadership experience in the life sciences industry, including as a chief executive officer, and her expertise in strategy, business transactions and strategic growth. OTHER PUBLIC COMPANY BOARDS • Halma Plc (2021-present) • Chair • Intertek Group Plc (2012-2021) • Atotech Ltd. (2020-2022)
COMMITTEES Audit & Finance SKILLS

INDEPENDENT

Vice Chair and President, Engineered Components at Aptiv PLC
EXPERIENCE Aptiv PLC, a global technology company (2013-Present) • Vice Chair and President, Engineered Components since November 2024 • Chief Financial Officer and Senior Vice President, Business Operations, March 2016 through November 2024 • Vice President and Corporate Controller inVentiv Health, a biopharmaceutical solutions organization (2010-2013) • Chief Financial Officer Liberty Lane Partners, a private equity firm (2008-2010) • Managing Director EDUCATION • MBA and a Master’s Degree in Accounting from Northeastern University • Bachelor’s Degree in Finance and Economics from Bentley University VALUE TO OUR BOARD The Board benefits from Mr. Massaro’s senior leadership experience, including as a chief financial officer, and his expertise in international business transactions, information technology and systems management, strategy and financial accounting (including qualification as an audit committee financial expert). OTHER PUBLIC COMPANY BOARDS None
COMMITTEES Audit & Finance (Chair) Nominating & Governance SKILLS

INDEPENDENT

17

Proposal 1 Election of Directors

Co-Founder and Managing Partner of Periphas Capital LP
EXPERIENCE Periphas Capital LP, a private equity firm focused on investing in technology- enabled businesses in services, consumer and industrial end markets (2017-present) • Co-Founder and Managing Partner Goldman Sachs & Co., a global investment banking, securities and investment management firm (1986-2016) • Vice Chairman of the Global Private Equity business • Co-Head of US Private Equity • Partner • Founding Member of Principal Investment Area (“PIA”) EDUCATION • MBA from Harvard Business School • Bachelor’s Degree in Economics from Harvard College VALUE TO OUR BOARD The Board benefits from Mr. Mehra’s extensive leadership experience as a Partner at Goldman Sachs, board and advisory experience across multiple industries and his experience in the areas of capital allocation, finance, strategy and international business transactions. OTHER PUBLIC COMPANY BOARDS • OPENLANE (previously KAR Auction Services) (2021-2026) • Pariphas Capital Partner Corporation (2020-2022)
COMMITTEES Audit & Finance Compensation & Human Resources SKILLS

INDEPENDENT

Chief Financial Officer for TriNet Group, Inc.
EXPERIENCE TriNet Group, Inc., a full-service Human Resources solutions company (2025-present) • Chief Financial Officer Teladoc Health, Inc., a telemedicine and virtual healthcare company (2019-2025) • Chief Financial Officer American Express, a global financial services corporation (2012-2019) • Chief Financial Officer of the Global Commercial Services segment PepsiCo, a leading multinational food and beverage corporation (1995-2012) • Various leadership positions, leading high growth business units EDUCATION • MBA from the India Institute of Management • Master’s Degree in Public and Private Management from Yale School of Management • Bachelor’s Degree in Computer Science and Engineering from Jadavpur University in India VALUE TO OUR BOARD The Board benefits from Ms. Murthy’s senior leadership experience, including as a chief financial officer, and her expertise in international business transactions, information technology and systems management, financial accounting and strategic growth (including qualification as an audit committee financial expert). OTHER PUBLIC COMPANY BOARDS None
COMMITTEES Audit & Finance SKILLS

INDEPENDENT

18 2026 Proxy Statement

Proposal 1 Election of Directors

Chief Executive Officer of Tessera Therapeutics, Inc.
EXPERIENCE Tessera Therapeutics, Inc., a biotechnology company (2022-Present) • Chief Executive Officer AbbVie Inc., a pharmaceutical company (2014-2022) • Vice Chairman and President • Executive Vice President, Research & Development • Chief Scientific Officer Amgen, Inc., a global biotechnology company (2004-2014) • Senior Vice President, Global Development • Chief Medical Officer EDUCATION • M.D. from Johns Hopkins University • Residency and Fellowship Training at Massachusetts General Hospital and Harvard Medical School • Bachelor’s Degree in Biochemistry from the University of Maryland VALUE TO OUR BOARD The Board benefits from Dr. Severino’s extensive leadership experience, including as a chief executive officer, and his current and past experience in research and development and corporate strategy for leading companies focused on developing life-saving therapies for patients. OTHER PUBLIC COMPANY BOARDS • Viatris, Inc. (2025-Present)
COMMITTEES Compensation & Human Resources (Chair) Science & Technology SKILLS

INDEPENDENT

19

Proposal 1 Election of Directors

Founder and Managing Partner of Glen Capital Partners
EXPERIENCE Glen Capital Partners, an investment fund (2014-present) • Founder and Managing Partner Star Mountain Capital, a specialized asset management firm (2023-present) • Seni or Advisor NextGen Acquisition Corp I & II, publicly traded special purpose acquisition companies (SPACs) (2020-2021) • Co-founder The Carlyle Group, a leading global investment firm (2009-2014) • Managing Director and Vice Chairman of Global Buyout Goldman Sachs Capital Partners, the private equity arm of Goldman Sachs (2008-2009) • Senior Advisor PerkinElmer, a global leader in health sciences (1998-2009) • Chairman and Chief Executive Officer AlliedSignal, now Honeywell International • President of General Aviation Avionics • President of the Aerospace Engines Group • President of the Automotive Products Group McKinsey & Co. • Partner EDUCATION • MBA with distinction from The Wharton School of the University of Pennsylvania • Master’s Degree in Electrical Engineering from University of Cincinnati • Bachelor’s Degree in Electrical Engineering from University of Kentucky VALUE TO OUR BOARD The Board benefits from Mr. Summe’s extensive leadership experience in key industries, including life sciences and applied materials, and his expertise in strategy, international business transactions, mergers and acquisitions and operations. OTHER PUBLIC COMPANY BOARDS • GRAIL, Inc. (2024-present) • Chair • NXP Semiconductors (2015-present) • Wheels Up Experience, Inc. (2024-present) • State Street Corporation (2001-2025) • Virgin Orbit Holdings, Inc. (2021-2023)
INDEPENDENT COMMITTEES Nominating & Governance (Chair) Compensation & Human Resources SKILLS

INDEPENDENT

20 2026 Proxy Statement

Corporate Governance

Our success is built and sustained by the trust we have earned from our customers, suppliers, distributors, associates,

business partners and investors. Part of this trust stems from our commitment to good corporate governance. The

framework for our governance practices is found in our Corporate Governance Guidelines, which outline the operating

principles of our Board of Directors and the composition and working processes of our Board and its committees. The

Nominating and Governance Committee periodically reviews our Corporate Governance Guidelines and developments in

corporate governance and periodically recommends proposed changes to the Board for approval.

Board and Governance Highlights

BOARD MEMBERSHIP AND PARTICIPATION
Directors are expected to spend the time needed and meet as often as necessary to discharge their responsibilities properly. Directors are expected to make every effort to attend all meetings of the Board, meetings of the committees of which they serve, and any meeting of stockholders. Directors generally may not serve on more than five public company boards (including Avantor’s Board). Members of the Audit and Finance Committee generally may not serve on more than three public company audit committees (including Avantor’s Audit and Finance Committee). Directors who also serve as executive officers or in equivalent positions generally should not serve on more than two public company boards (including Avantor’s Board).
PROHIBITIONS AGAINST SHORT SALES, HEDGING, MARGIN ACCOUNTS AND PLEDGING
Our Insider Trading Policy contains restrictions applying to all directors, officers and employees that, among other things:
Prohibit short sales of Avantor securities and derivative or speculative transactions in Avantor securities; Prohibit the use of financial instruments (including prepaid variable forward contracts, equity swaps, collars and exchange funds) that are designed to hedge or offset any decrease in the market value of Avantor securities; and Prohibit holding Avantor securities in margin accounts or pledging Avantor securities as collateral for a loan.
ROBUST STOCKHOLDER RIGHTS
Directors are elected under a “majority voting” standard in uncontested elections. Directors who do not receive the requisite votes for re-election must resign, subject to acceptance of such resignation by the Board. Each stockholder, or a group of up to 20 stockholders, that has continuously owned for three years at least 3% of our outstanding common shares, may nominate and include in the annual meeting proxy materials up to the greater of two directors or 20% of the number of directors serving on the Board, if the stockholder(s) and the nominee(s) meet the requirements specified in our fourth amended and restated bylaws ("bylaws"). We do not currently have a rights plan (or "poison pill") in place. Future action by stockholders to alter, amend or repeal our fourth amended and restated certificate of incorporation can be approved by the affirmative vote of a majority of the outstanding stock entitled to vote thereon, and if applicable, a majority of the outstanding stock of each class entitled to vote thereon as a class. Stockholders of record who own common shares representing at least 20% of the relevant voting power continuously for at least one year can call a special meeting of stockholders, subject to certain requirements.

21

Corporate Governance

The Structure and Role of the Board of Directors

Board Leadership Structure

Following a deliberate, disciplined succession planning process, in 2025 the Board announced two leadership transitions

for the roles of non-executive Chairman and President and CEO.

Gregory Summe Non-executive Chairman since January 1, 2026 Emmanuel Ligner President and CEO since August 18, 2025

Avantor’s Board is led by Gregory Summe, a non-executive Chairman who assumed that role at the beginning of January

2026 when Jonathan Peacock retired from the Board after almost nine years of service. The Board believes that it is in the

best interest of the Company and its stockholders for Mr. Summe to serve as Chairman of the Board due to his extensive

experience in the life sciences and applied materials sector and his expertise in strategy, international business

transactions, mergers and acquisitions and operations.

We believe that having an independent, non-executive Chairman emphasizes the importance of the Board’s objectivity and

independence from management and best promotes the effective functioning of the Board’s oversight role. In addition, this

structure allows Mr. Ligner to focus on the day-to-day management of the business and on executing our strategic priorities.

Mr. Summe’s responsibility is to ensure that our Board functions properly and to work with our President and Chief Executive

Officer to set the Board’s agenda. We expect him to facilitate communications among our directors and between the Board

and senior management. While Mr. Summe provides independent leadership, he also works closely with our Chief Executive

Officer to ensure that our directors receive the information that they need to perform their responsibilities, including

discussing and providing critical review of the matters that come before the Board and assessing management’s

performance.

Although we believe that the separation of the Chairman and Chief Executive Officer positions is appropriate corporate

governance for us at this time, our Board believes that the Company and stockholders are best served by maintaining the

Board’s flexibility to determine whether and when the Chairperson and CEO positions should be separate or combined to

provide the appropriate leadership. If the two roles were combined, or the role of Chair was held by another director who

is not independent, the independent directors would elect an independent Lead Director who would have robust

responsibilities described in our Corporate Governance Guidelines.

The Board’s Oversight of Strategy

The Board is deeply engaged and involved in overseeing Avantor’s long-range strategy, including evaluating key market

opportunities, customer and supplier trends, and competitive developments. The Board also oversees aspects of our

corporate sustainability and governance initiatives that relate to our strategy. The Board’s oversight of risk is another

integral component of the Board’s oversight and engagement on strategic matters. Strategy-related matters are regularly

discussed at Board meetings and, when relevant, at committee meetings. We also dedicate at least one Board meeting

every year to an even more intensive review and discussion of the Company’s strategic plan. Matters of strategy also

inform committee-level discussions of many issues, including enterprise risk. Engagement of the Board on these issues

and other matters of strategic importance continues in between meetings, including through updates to the Board on

significant items and discussions between the CEO and our Chairman on a periodic basis. Each director is expected to

bring to bear their own talents, insights, and experiences to these strategy discussions.

22 2026 Proxy Statement

Corporate Governance

The Board’s Role in Risk Oversight

While senior management has primary responsibility for managing risk, the Board has responsibility for risk oversight. As

shown below, specific risk areas are delegated to relevant Board committees, who report on their deliberations to the full

Board.

Board of Directors
• Oversee Avantor’s risk governance framework, including an enterprise-wide culture that supports appropriate risk awareness and identification, escalation and management of risk • Integrity, ethics and compliance with our Code of Ethics and Conduct • General strategic and commercial risks • M&A transactions, including execution and integration, and the M&A competitive landscape • Legal risks such as those arising from litigation and environmental and intellectual property matters
Audit and Finance Committee Compensation and Human Resources Committee
• Coordination of work between Avantor’s internal and external auditors • Accounting, controls and financial disclosure • Avantor’s Enterprise Risk Management (“ERM”) program • Cybersecurity risk, including our information security framework, threat assessment, response readiness and training efforts • Tax and liquidity management • Compensation structure and programs • Management succession planning • Associate engagement initiatives • Talent selection, leadership development and performance reviews • Workplace culture • Workplace health, safety and well-being
Science and Technology Committee Nominating and Governance Committee
• Avantor’s scientific and technological innovation strategies • Research and development plans and goals • Avantor’s Scientific Advisory Board • Governance structures and process • Board organization, independence and structure • Board succession and effectiveness • Sustainability initiatives
Management
Responsible for the identification, assessment and management of risks through our ERM program

23

Corporate Governance

Enterprise Risk Management

The Board uses the ERM program as a key tool for understanding the inherent risks facing Avantor and assessing

whether management’s processes, procedures and practices for mitigating those risks are effective. The ERM

assessment, which is led by our internal ERM function, evaluates key risks related to strategies, finances, operations,

compliance, personnel and external factors. The ERM approach encourages collaborative and constructive

communication; facilitates effective tracking, testing, planning and goal setting for key risks; and enhances preparedness

for senior leaders and the Board in addressing emerging risks and opportunities.

In 2025, the ERM program included consideration of risks in six distinct risk categories and seventeen key risks overall.

Each key risk has an Executive Leader assigned as the risk owner, and each risk deemed to be the highest risk receives

additional ongoing oversight.

Both the Audit and Finance Committee and the Board review the results of the annual ERM assessment. During the

reviews, Avantor’s Senior Director of ERM, partnering with each Executive Leader risk owner, presents the results of the

ERM assessment in a manner designed to provide full visibility into the risks facing Avantor and how management is

mitigating those risks, thereby enabling the Board to effectively exercise its oversight function. To facilitate continued

monitoring and oversight by the Board, key risk areas identified during the ERM process and management’s associated

mitigation activities become part of Board and/or committee meeting agendas for the following year.

The Board’s Oversight of Corporate Sustainability Matters

Considering the wide range of sustainability concerns relevant to a company of our size and scale, responsibility for

overseeing these matters is distributed across the Board and its committees:

Responsible Party Oversight Areas for Corporate Sustainability Matters
Full Board Sustainability governance, strategy and risks (through oversight of strategic risks)
Audit and Finance Committee • Ethics and compliance • Product quality and safety • Data privacy and security
Compensation and Human Resources Committee • Talent selection, leadership development and performance review • Workplace initiatives and progress • Employee relations • Workplace culture • Workplace health, safety and well-being
Nominating and Governance Committee • Governance structures and processes • Board organization, independence and structure • Board succession and effectiveness • Sustainability, corporate responsibility and citizenship matters

At the management level, our sustainability matters are led and coordinated by our Vice President, Global Sustainability

and Impact and Senior Vice President, Global Communications and Branding. These individuals regularly engage with the

Board’s Nominating and Governance Committee. The Vice President, Global Sustainability and Impact is responsible for

matters including, but not limited to:

regularly assessing priorities to identify the most significant topics for our stakeholders;

working closely with senior leaders to integrate sustainability-related priorities into our business operations; and

establishing and managing sustainability-related goals, as well as overseeing the collection, measurement and

reporting of corporate sustainability data.

24 2026 Proxy Statement

Corporate Governance

Committees of the Board

The Board has four standing committees: Audit and Finance, Compensation and Human Resources, Nominating and

Governance, and Science and Technology. The information below sets forth the members of each committee as of March

13, 2026.

Committee Charters

Our Audit and Finance, Compensation and Human Resources, Nominating and Governance and Science and Technology

committee charters are available on the investor relations portion of our website at www.avantorsciences.com under

“Investors: Governance.” These charters are reviewed by the various committees at least annually, and more frequently if

appropriate in light of emerging practices. Charters may be revised upon recommendation to and approval by the Board.

25

Corporate Governance

Au dit and Finance Committee

Our Audit and Finance Committee is responsible for, among other things:

selecting and hiring our independent auditors, and approving the audit and non-

audit services they will perform;

assisting the Board of Directors in evaluating the qualifications, performance and

independence of our independent auditors;

assisting the Board of Directors in monitoring the quality and integrity of our

financial statements and our accounting and financial reporting;

reviewing the adequacy and effectiveness of our internal control over financial

reporting processes;

Joseph Massaro (Chair)

reviewing with management and our independent auditors our annual and

quarterly financial statements;

establishing procedures for the receipt, retention and treatment of complaints

received by Avantor regarding accounting, internal accounting controls or

auditing matters, and for the confidential, anonymous submission by our

employees of concerns regarding questionable accounting or auditing matters;

Juan Andres

overseeing the Company’s internal audit function;

preparing the audit committee report that the Securities and Exchange

Commission (the “SEC”) requires in our annual Proxy Statement; and

reviewing related-party transactions.

Our Audit and Finance Committee consists of Messrs. Massaro, Andres,

Simon Dingemans*

Dingemans and Mehra, Dame Louise and Ms. Murthy, with Mr. Massaro serving as

chair.

All members of the Audit and Finance Committee have been determined to be

“independent,” consistent with our Audit and Finance committee charter, Corporate

Governance Guidelines, SEC rules and the New York Stock Exchange (“ NYSE”)

listing standards applicable to boards of directors in general and audit committee

Dame Louise Makin

members in particular. The Board has also determined that each of the members of

the Audit and Finance Committee is “financially literate” within the meaning of the

NYSE listing standards. In addition, the Board has determined that

Messrs. Massaro and Dingemans and M s. Murthy qualify as “audit committee

financial experts,” as defined by applicable SEC regulations. No committee member

currently sits on more than two other public company audit committees.

Sanjeev Mehra*

Mala Murthy

8

Meetings in

2025

  • Messrs. Dingemans and Mehra joined the committee in February of 2026.

26 2026 Proxy Statement

Corporate Governance

Co mpensation and Human Resources Committee

The Compensation and Human Resources Committee is responsible for, among

other things:

reviewing and approving corporate goals and objectives relevant to the

compensation of our CEO, evaluating our CEO’s performance in light of those

goals and objectives, and, together with the other independent directors (as

directed by the Board of Directors), determining and approving our CEO’s

compensation level based on such evaluation;

reviewing and approving, or making recommendations to the Board of Directors

with respect to, the compensation of our other executive officers, including

annual base salary, bonus, equity-based incentives and other benefits;

Michael Severino (Chair)

overseeing the Company’s savings, retirement, health and welfare plans;

reviewing the Company’s management development and succession planning

process;

reviewing and making recommendations to our Board of Directors with respect to

the compensation of our directors; and

reviewing and making recommendations with respect to our equity compensation

Lan Kang

plans.

The Compensation and Human Resources Committee has sole authority to retain

or terminate any compensation consultant or other advisor used to evaluate senior

executive compensation and may form and delegate authority to subcommittees

when appropriate. The Compensation and Human Resources Committee also

Gregory Lucier

approves all engagements and services to be performed by any consultants or

advisors to the Compensation and Human Resources Committee. To assist the

Compensation and Human Resources Committee in discharging its responsibilities,

the committee has retained an independent compensation consultant—Frederic W.

Cook & Company (“FW Cook”). FW Cook reports directly to the Compensation and

Human Resources Committee. For more information about the independence of the

Compensation and Human Resources Committee’s consultant, refer to

Sanjeev Mehra*

“Compensation Discussion and Analysis — Compensation Philosophy & Objectives

— How We Make Compensation Decisions — Guidance from the Independent

Compensation Consultant.” For more information on the responsibilities and

activities of the Compensation and Human Resources Committee, including its

processes for determining executive compensation, see “Executive Compensation

— Compensation Discussion and Analysis.”

Gregory Summe

Our Compensation and Human Resources Committee consists of Messrs.

5

Meetings in

2025

Severino, Lucier, Mehra and Summe and Ms. Kang, with Mr. Severino serving as

chair.

All members of the Compensation and Human Resources Committee have been

determined to be “independent,” consistent with our Compensation and Human

Resources Committee Charter, Corporate Governance Guidelines, SEC rules and

the NYSE listing standards applicable to boards of directors in general and

compensation committee members in particular. In addition, all members qualify as

“non-employee directors” for purposes of Rule 16b-3 under the Exchange Act.

  • Mr. Mehra joined the committee in February of 2026.

27

Corporate Governance

Nominati ng and Governance Committee

The Nominating and Governance Committee is responsible for, among other

matters:

assisting our Board of Directors in identifying prospective director nominees and

recommending nominees to the Board of Directors;

overseeing the evaluation of the Board of Directors and management;

identifying best practices and recommending corporate governance principles;

reviewing developments in corporate governance practices and developing a set

of corporate governance guidelines;

recommending members for each committee of our Board of Directors; and

Gregory Summe (Chair)

overseeing sustainability and corporate responsibility.

Our Nominating and Governance Committee consists of Messrs. Summe,

Carethers, Lucier, Massaro and Dame Louise.

John Carethers

Gregory Lucier

Dame Louise Makin

Joseph Massaro*

3

Meetings in

2025

  • In 2026, Mr. Lucier succeeded Mr. Summe as the committee chair and Mr. Massaro joined the committee.

28 2026 Proxy Statement

Corporate Governance

Science and Technology Committee

The Science and Technology Committee is responsible for, among other matters:

reviewing and evaluating the Company’s scientific and technological innovation

strategies and research and development plans and goals, including with respect

to its capital allocation, business development and acquisition priorities;

reviewing and evaluating the Company’s performance relating to its research and

development plans and goals;

identifying and discussing significant emerging science and technology trends,

including their potential impact on the Company’s scientific and technological

innovation strategies and research and development goals;

assessing the competitive position of the Company’s intellectual property

Juan Andres (Chair)

portfolio; and

assisting management in overseeing the Company’s Scientific Advisory Board.

Our Science and Technology Committee consists of Messrs. Andres, Carethers, and

Severino, with Mr. Andres serving as chair.

John Carethers

Michael Severino

4

Meetings in

2025

29

Corporate Governance

Board Policies a nd Practices

Board and Committee Evaluations

The Board of Directors annually assesses the effectiveness of the full Board, the operations of its committees, and the

contributions of director nominees. The Nominating and Governance Committee oversees the evaluation of the Board as

a whole and its committees, as well as individual evaluations of those directors who are being considered for possible re-

nomination to the Board. In 2025, the evaluation was conducted by an experienced outside facilitator who interviewed all

members of the Board as well as some certain members of members from executive leadership. Feedback gathered by

the facilitator was then shared with the Nominating and Governance Committee as well as the full Board.

Director Independence and Independence Determinations

The Board reviews the independence of all directors at least annually. Our Corporate Governance Guidelines define an

“independent” director in accordance with Section 303A.02 of the NYSE Listed Company Manual. Moreover, under our

Corporate Governance Guidelines and NYSE rules, a director is not independent unless the Board affirmatively

determines that they do not have a material relationship with us or any of our subsidiaries (either directly or as a partner,

stockholder or officer of an organization that has a relationship with us or any of our subsidiaries). Members of our Audit

and Finance Committee and Compensation and Human Resources Committee are subject to enhanced independence

requirements under SEC rules and NYSE listing standards.

If a director has a relationship with Avantor that is relevant to their independence and is not addressed by the objective

tests set forth in the NYSE independence definition, including any relationship described under “Certain Relationships and

Related Person Transactions” below, the Board will determine, considering all relevant facts and circumstances, whether

such relationship is material.

The Board has affirmatively determined that every director except Mr. Ligner, our CEO, and Mr. Stubblefield, our former

CEO, is independent under the guidelines for director independence set forth in our Corporate Governance Guidelines

and the applicable NYSE listing standards, including with respect to committee memberships where applicable.

Executive Sessions

To ensure free and open discussion and communication among the non-management directors of the Board, the non-

management directors meet in executive session at most Board meetings. The Chairman presides at the executive

sessions.

Board Meetings and Attendance

The Board met seven times in 2025, including regularly scheduled and special meetings. Each director attended 75% or

more of the aggregate of all meetings of the Board and the committees on which they served during 2025 with the

exception of Mr. Ligner who was unable to attend a special meeting of the Board due to a prior commitment and, as a

result, attended 67% of all meetings.

Under Avantor’s Corporate Governance Guidelines, all directors are expected to make every effort to attend all meetings

of the Board, meetings of the committees of which they are members, and any meeting of stockholders. Dire ctors are

encouraged to attend these meetings in person, but may also attend by telephone or video conference.

30 2026 Proxy Statement

Corporate Governance

Director Orientation and Continuing Education

Directors receive an in-depth orientation to Avantor upon joining the Board and continue to receive ongoing education and

training aligned with our business and industry.

New Director Orientation Each new director participates in an orientation program covering: • Avantor’s governance documents, including our: Certificate of Incorporation, Bylaws, Committee Charters, Corporate Governance Guidelines and director and officer Insurance details; • Avantor’s key policies, such as our: Code of Conduct, Director Compensation Policy, Insider and Related Party Transactions Policies, Whistleblower Policy, Clawback Policy and Global Disclosure Standard; and • Meetings with senior leaders to discuss: business and strategy, significant financial matters, information technology and security, legal, quality and regulatory matters, the ethics and compliance program and workforce management approach.
Continuing Director Education To keep our Board informed, we deliver ongoing education and training sessions during the year, guided by director and executive input and focused on developments and emerging risks relevant to our business. Ongoing director education may include: • Expert-led presentations on a variety of topics; • Management briefings covering the company’s business, services, products, industry trends and key current and emerging risks; and • Guided tours of company facilities. In 2025, we hosted outside experts to present during Board meetings on topics related to the current macroeconomic and political environment and the impacts to our company and industry.

31

Corporate Governance

Stockholder Engagement Program

Our Annual Engagement Process

We believe that meeting with stockholders and other key stakeholders provides our Board and leadership team with

valuable insights into important issues impacting our business. We have developed a robust stockholder engagement

program that enables us to share important business updates and solicit stockholder feedback on key issues.

We engage with stockholders and other market participants throughout the year through a variety of channels, including

quarterly earnings discussions, investor conferences and investor meetings. We meet with analysts, portfolio managers,

proxy voting teams and other key market participants. Engagements with stockholders can cover a variety of topics,

including financial performance and corporate strategy. Importantly, our governance-focused stockholder engagement

program enables us to better connect with stockholders on issues that are not regularly addressed through traditional

investor relations channels, such as corporate governance, executive compensation and sustainability.

Engagements are led by members of our senior management team and, in connection with our governance-focused

stockholder engagement program, have also included participation from independent directors from our Board. The

senior leadership team and Board regularly review stockholder feedback and consider it when evaluation our governance

practices and long-term strategic priorities.

Year-round Stockholder Engagement Throughout quarterly earnings, conferences and investor meetings — Summer Fall Winter Spring
• Review Annual Meeting results and engagement feedback with senior management team and Board • Begin preparations for fall engagement • Conduct “off-season” engagements with investors, covering a wide variety of governance and sustainability-related topics • Review “off-season” feedback from investors • Prepare Annual Report and Proxy Statement • Conduct “in-season” conversations with investors on specific proxy ballot items • Host Annual Meeting • Release Sustainability Report

32 2026 Proxy Statement

Corporate Governance

Our 2025 Engagement Efforts

2025 was a pivotal year for Avantor on many fronts and was an important year

for strengthening our relationships with our stockholders. Over the course of

the year, we met with stockholders representing a significant portion of our

shares outstanding.

Governance-oriented engagements are led by members of our senior

leadership team, including representatives from investor relations, legal, HR,

and sustainability. Our new Board Chairman and Chair of our Nominating and

Governance Committee, Gregory Summe, participated in discussions with

many of our top stockholders.

WE ENGAGED WITH INVESTORS REPRESENTING
74% of shares outstanding in 2025

Our discussions over the past year covered a wide range of topics. Key areas of focus included:

Strategic and operational priorities, including Avantor Revival

Financial performance and capital allocation priorities

Key leadership appointments, including our CEO transition and new COO

Board composition and refreshment

Board Chairman transition

Executive compensation practices

Sustainability priorities and progress

The senior leadership team and Board appreciate the relationship with our stockholders and will continue to thoughtfully

review the feedback provided through this process.

For more information on our stockholder engagement efforts with respect to last year’s say-on-pay vote and executive

compensation, see “Executive Compensation — Compensation Discussion and Analysis — 2025 Say-on-Pay and

Stockholder Engagement.”

Governance Documents

Our Corporate Governance Guidelines, committee charters, Code of Ethics and Conduct, and other corporate governance

materials are available on the investor relations portion of our website at www.avantorsciences.com under “Investors:

Governance.” Any stockholder also may request them in print, without charge, by contacting the Corporate Secretary:

Avantor Inc., Corporate Secretary’s Office, Radnor Corporate Center, Building One, Suite 200, 100 Matsonford Road,

Radnor, PA 19087.

Committee Charters and Corporate Governance Guidelines

Our commitment to good corporate governance is reflected in our Corporate Governance Guidelines, which describe the

Board’s views on a wide range of governance topics. Our Corporate Governance Guidelines and committee charters are

reviewed not less than annually by the various committees and, to the extent deemed appropriate in light of emerging

practices, revised accordingly, upon recommendation to and approval by the Board.

33

Corporate Governance

Code of Ethics and Conduct

We have a written Code of Ethics and Conduct that applies to all of the directors, officers and employees, including our

President and Chief Executive Officer, Chief Financial Officer, Chief Accounting Officer and other senior executive officers.

Our Code of Ethics and Conduct sets forth policies and expectations on a number of topics, including conflicts of interest,

compliance with laws, use of company assets, and our business practices.

Were we to amend or waive any provision of our Code of Ethics and Conduct that applies to our principal executive officer,

principal financial officer, principal accounting officer, or any person performing similar functions, we intend to satisfy our

disclosure obligations, if any, with respect to any such waiver or amendment by posting such information on our website at

www.avantorsciences.com rather than by filing a Form 8-K. In the case of a waiver for an executive officer or a director,

the required disclosure will also be made available on our website.

Communications with Directors

The Board of Directors welcomes input and suggestions. Stockholders and other interested parties may contact the Board

and our Chairman by sending a written communication by mail to Avantor, Inc., Corporate Secretary’s Office, Radnor

Corporate Center, Building One, Suite 200, 100 Matsonford Road, Radnor, PA 19087.

Communications addressed to the Board generally or to one or more specific Board members are promptly distributed as

addressed unless a communication is considered to be improper for submission to the intended recipient or recipients.

Examples of communications that would presumptively be deemed improper for submission include solicitations,

communications that raise grievances that are personal to the sender, communications that relate to the pricing of the

Company’s products or services, communications that do not relate directly or indirectly to the Company, and

communications that are frivolous in nature.

Certain Relationships a nd Related

Person Transactions

The Board of Directors has adopted a written Related Person Transaction Policy to assist it in reviewing, approving and

ratifying transactions with related persons where the amount involved exceeds $120,000 and to assist us in the

preparation of related disclosures required by the SEC. This Related Person Transaction Policy supplements our other

policies that may apply to transactions with related persons, such as our Corporate Governance Guidelines and Code of

Ethics and Conduct.

Under our Related Party Transaction Policy, our Audit and Finance Committee is responsible for the review, approval and

ratification of “related person transactions” between us and any related person. “Related party transactions” include any

transaction by the Company with a company or other entity that employs a “related party,” or in which a “related party” has

a material ownership or financial interest. Under SEC rules, a related person is an officer, director, nominee for director or

beneficial holder of more than 5% of any class of our voting securities since the beginning of the last fiscal year or an

immediate family member of any of the foregoing.

In the course of its review of a related-person transaction, the Audit and Finance Committee will consider:

the nature of the related person’s interest in the transaction;

the material terms of the transaction, including the amount involved and type of transaction;

the importance of the transaction to the related person and to our Company;

whether the transaction would impair the judgment of a director or executive officer to act in Avantor’s best interest and

the best interests of our stockholders; and

any other matters the Audit and Finance Committee deems appropriate.

34 2026 Proxy Statement

Corporate Governance

Each director and officer completes a questionnaire at the end of each fiscal year to confirm that there are no material

relationships or related person transactions between such individual and the Company other than those previously

disclosed to Avantor. This annual process ensures that all material relationships and related person transactions are

identified, reviewed and disclosed in accordance with applicable policies, procedures and regulations.

Any member of the Audit and Finance Committee who is a related person with respect to a transaction under review will

not participate in the deliberations or vote on the approval or ratification of the transaction. However, such a director may

be counted in determining the presence of a quorum at a meeting of the committee that considers the transaction.

Arrangements with Our Directors and Officers

We have certain agreements with our directors and officers that are described in the sections entitled “Director

Compensation” and “Narrative Disclosure to Summary Compensation Table and Grants of Plan-Based Awards in 2025 ”

elsewhere in this Proxy Statement.

We entered into indemnification agreements with our officers and directors. These agreements and our bylaws will require

us to indemnify these individuals to the fullest extent permitted under Delaware law against liabilities that may arise by

reason of their service to us, and to advance expenses incurred as a result of any proceeding against them as to which

they could be indemnified. The indemnification provided under the indemnification agreements will not be exclusive of any

other indemnity rights. Insofar as our agreements may permit indemnification to directors for liabilities arising under the

Securities Act, we have been informed that in the opinion of the SEC such indemnification is against public policy and may

be unenforceable.

In the normal course of business, we purchase services, supplies, and equipment from many suppliers and sell goods and

services to many customers. In some instances, these transactions occur with companies with which members of our

Board have relationships as executive officers. For transactions entered into during 2025, no related person had or will

have a direct or indirect material interest.

While not required under the Related Person Transaction Policy, the Board reviewed overall spending with Tessera

Therapeutics, where Dr. Severino serves as Chief Executive Officer; GRAIL, Inc., where Mr. Summe serves as the chair of

the board; UCB, where Mr. Peacock serves as the chair of the board; Lonza Group, where Mr. Andres serves as a

director, and the University of California San Diego, where Dr. Carethers serves as the Vice Chancellor for Health

Sciences.

Commitment t o Sustainability

Avantor's Science for Goodness sustainability strategy is a key part of our commitment to deliver long-term value to our

customers, associates, suppliers, communities and stockholders. This platform aims to foster a culture of belonging,

promote innovation for a sustainable future, support and strengthen our communities, and add value to Avantor. As our

customers look to us to support their sustainability goals, we are embedding sustainable practices throughout our

operations to reduce our greenhouse gas emissions and resource use, provide more environmentally preferable products

for our customers, and ensure a responsible and resilient supply chain.

Science for Goodness: Our Approach to Sustainability

Avantor sets sustainability strategy and reporting priorities by understanding our stakeholders’ expectations, surveying the

evolving reporting landscape and prioritizing strategies that drive long-term value for the Company and stakeholders. Our

impact and purpose are centered on four key commitment pillars aligned with the following UN Sustainable Development

Goals: Good Health & Wellbeing, Quality Education, Industry, Innovation and Infrastructure, Reduced Inequalities, and

Responsible Consumption and Production.

35

Corporate Governance

Throughout 2026, we advanced our corporate sustainability strategy across each of these four pillars.

Pillar Goal Spotlights on Progress
People and Culture • Expand associate engagement opportunities. • Achieve top health & safety performance. • Grew Associate-Centric Team (ACT), or employee resource group, engagement with our frontline associates with a 53% increase in on-site events and activities. • Our ACTs are open to all associates, with 31% of our total workforce participating in one or more ACTs. • Advanced associate career growth with a 33% increase in use of tools that enrich development conversations and recommend mentor connections--resulting in improved associate engagement and growth sentiment. • Achieved total recordable incident rate (TRIR) of 0.29, a 42% reduction from the 2020 baseline and continuing to place us in the top quartile for safety performance in our relevant industries.
Innovation and Environment By 2030: • Reduce absolute Scope 1 and 2 emissions by 50% • Reduce absolute Scope 3 emissions by 25% *from a 2020 baseline • Met our annual Scope 1 and 2 GHG emissions reduction target. • Near-term climate targets verified by the Science-based Target Initiative (SBTi). • Achieved LEED ID+C Silver Certification for our expanded Bridgewater Innovation Center in New Jersey. • Offer 40,000+ items through our Environmentally Preferable Products Program globally.
Community Engagement • Increase associate volunteer hours. • Improve global access to STEM education and healthcare. • Associates volunteered more than 25,000 hours through our corporate sponsored events, Dollars for Doers program and Volunteer Time Off benefits. This represents an increase of over 30% from prior year. • Grew unique associate participation in our matching and volunteerism programs to 32% globally.
Governance and Integrity • Expand Avantor's Responsible Supplier Program. • Achieved Ecovadis Bronze rating for third year in a row. • 60% of suppliers by spend enrolled in the Avantor Responsible Supplier Program, which ensures Avantor suppliers are well- positioned to help us meet the sustainability challenges of the future. • 50% of suppliers by emissions have set climate targets.

36 2026 Proxy Statement

Corporate Governance

Reporting

Our annual Avantor Corporate Sustainability Report, released in June 2025, is available on our website. The 2025 report

outlines progress made on our four sustainability pillars and highlights how our associates are helping to advance Science

for Goodness. Our corporate sustainability reports continue to include the Sustainability Accounting Standards Board’s

(SASB) reporting disclosure for the Medical Equipment & Supplies, Biotechnology & Pharmaceuticals, and Chemicals

industries, and the information called for by the Task Force for Climate Disclosure. We also continue to disclose climate

strategies and metrics through CDP Climate Questionnaire (formerly Carbon Disclosure Project). For more information on

our sustainability goals, see our website, www.avantorsciences.com , under “About: Sustainability.”

37

Director Compensation

Our director compensation program is designed to attract and retain qualified non-employee directors. With assistance

from FW Cook, we developed a market-based program that aligns director compensation with the compensation paid by

our peers. For more information about our peer companies, see “Compensation Philosophy & Objectives — How We

Make Compensation Decisions — Benchmarking.” Our Compensation and Human Resources Committee reviews non-

employee director compensation regularly to confirm that it appropriately addresses the time, effort, expertise, and

accountability required of active board membership.

Director Fees

Our director compensation program provides for an annual cash retainer plus an annual equity award of restricted stock

units. Additional retainers are paid for service on certain committees and for chairing the Board or one of its committees.

Compensation Element $
Annual Cash Retainer 95,000
Annual Equity Award 210,000
Chairman Cash Retainer 170,000
Committee Chair Cash Retainer
Audit and Finance Committee 25,000
Compensation and Human Resources Committee 20,000
Nominating and Governance Committee 15,000
Committee Member (excluding Committee Chair) Cash Retainer
Audit and Finance Committee 12,500
Compensation and Human Resources Committee 10,000
Nominating and Governance Committee 7,500

Director cash retainers are paid quarterly in arrears. Director equity awards are issued in restricted stock units on the date

of the annual meeting and vest in full one year later. If a director has continuously provided service to us upon the

occurrence of a change in control prior to a vesting date, all of the director’s then-unvested restricted stock units will vest.

The annual equity-based retainer will be pro-rated for partial years of service.

Eligible directors also are entitled to receive reimbursement for reasonable travel, lodging and other expenses that they

properly incur in connection with their functions and duties as a director.

Deferred Compensation

Non-employee directors have the option of deferring the receipt of their annual equity compensation. Pursuant to our

deferred compensation plan, deferrals of common stock are adjusted to reflect the hypothetical reinvestment in additional

shares of common stock for any dividends or other distributions on common stock during the deferral period. A non-

employee director may elect to have their deferred amounts paid after five years, ten years or at the termination of Board

service.

The following table provides summary information concerning the compensation of the non-employee members of our

Board of Directors for the year ended December 31, 2025. The compensation paid to Messrs. Stubblefield and Ligner is

presented in the Summary Compensation Table and the other compensation tables below. During 2025, Messrs.

Stubblefield and Ligner did not receive additional compensation for their services as directors.

38 2026 Proxy Statement

Director Compensation

Name Fees Earned or Paid in Cash ($) (1) Stock Awards ($) (2) All Other Compensation ($) (3) Total ($)
Juan Andres 107,500 209,988 317,488
John Carethers 102,500 209,988 312,488
Lan Kang 105,000 209,988 314,988
Gregory T. Lucier (4) 26,413 124,849 151,262
Dame Louise Makin 110,496 209,988 12,099 332,583
Joseph Massaro 120,000 209,988 329,988
Sanjeev Mehra (4) 7,228 88,602 95,830
Mala Murthy 107,500 209,988 317,488
Jonathan Peacock (5) 272,500 209,988 482,488
Michael Severino 115,000 209,988 324,988
Gregory Summe 120,000 209,988 329,988

(1) Amounts reflect the director’s cash retainer earned for 2025.

(2) Amounts reflect the grant date fair value of restricted stock units granted under the 2019 Equity Incentive Plan, calculated in

accordance with Financial Accounting Standards Board Accounting Standards Codification Topic 718, Compensation — Stock

Compensation (“Topic 718”) disregarding the effects of estimated forfeitures. The assumptions made in the valuation of our equity

awards are found in Note 18 to our audited financial statements included in our Annual Report on Form 10-K for the year ended

December 31, 2025. As of December 31, 2025, each of the following non-employee directors held the following unvested restricted

stock units: Mr. Andres—17,100; Dr. Carethers—17,100; Ms. Kang—17,100; Mr. Lucier—8,736; Dame Louise—17,100; Mr. Massaro

—17,100; Mr. Mehra—8,106; Ms. Murthy—17,100; Mr. Peacock—17,100; Dr. Severino—17,100; Mr. Summe—17,100.

(3) Includes $12,099 paid to Ernst & Young on behalf of Dame Louise to support tax preparation. This amount was converted from

British Pounds Sterling to U.S. dollars based on the exchange rate as of the close of business on December 31, 2025 (1.3444).

(4) Mr. Lucier and Mr. Mehra joined our Board in October 2025 and December 2025, respectively.

(5) Mr. Peacock retired from our Board effective December 31, 2025. In connection with Mr. Peacock’s departure from our Board, the

restricted stock units that he was awarded in 2025 were forfeited.

Stock Ownership Guidelines

We have adopted equity ownership guidelines for our non-employee directors in order to better align their financial

interests with those of our stockholders. Each non-employee director must own shares of Avantor common stock in an

amount equal to five times (5x) his or her base annual cash retainer (excluding additional annual cash retainers for service

as the Chairman of the Board of Directors, lead independent director, committee chairpersons and committee members).

Directors are required to achieve the applicable level of ownership within five years of joining our Board. As of

December 31, 2025, all of our non-employee directors were either in compliance with the stock ownership guidelines or

had not yet completed their fifth year of service.

39

Stock Ownership Information

Stock Ownership Information

Avantor Stock Ownership

The following table sets forth information regarding the beneficial ownership of shares of our common stock as of March 2,

2026 by:

(1) each individual or entity known by us to beneficially own more than 5% of our outstanding common stock,

(2) each of our named executive officers,

(3) each of our directors, and

(4) all of our directors and our current executive officers as a group.

The amounts and percentages of shares beneficially owned are reported on the basis of SEC regulations governing the

determination of beneficial ownership of securities. Under SEC rules, a person is deemed to be a “beneficial owner” of a

security if that person has or shares voting power or investment power, which includes the power to dispose of or to direct

the disposition of such security. A person is also deemed to be a beneficial owner of any securities of which that person

has a right to acquire beneficial ownership within 60 days. Securities that can be so acquired are deemed to be

outstanding for purposes of computing such person’s ownership percentage, but not for purposes of computing any other

person’s percentage. Under these rules, more than one person may be deemed to be a beneficial owner of the same

securities, and a person may be deemed to be a beneficial owner of securities as to which such person has no economic

interest.

Unless otherwise set forth in the footnotes below, (i) each beneficial owner possesses, to our knowledge, sole voting and

investment power with respect to the shares listed, subject to community property laws where applicable, and (ii) the

address of each beneficial owner is c/o Avantor, Inc., Radnor Corporate Center, Building One, Suite 200, 100 Matsonford

Road, Radnor, PA 19087.

40 2026 Proxy Statement

Name of Beneficial Owner Shares beneficially owned Percent of total common stock (1)
Greater than 5% stockholders:
Dodge & Cox (2) 117,433,484 17.4%
BlackRock, Inc. (3) 59,049,575 8.7%
The Vanguard Group, Inc. (4) 65,344,584 9.7%
Named executive officers and directors:
Emmanuel Ligner 87,500 *
R. Brent Jones 266,862 *
Benoit Gourdier 115,107 *
Claudius Sokenu 84,905 *
Corey Walker 73,554 *
Michael Stubblefield (5) 7,680,907 1.1%
Juan Andres 48,380 *
John Carethers 28,758 *
Simon Dingemans *
Lan Kang 30,215 *
Gregory Lucier (6) 50,000 *
Louise Makin 4,770 *
Joseph Massaro 35,038 *
Sanjeev Mehra (7) 350,000 *
Mala Murthy 27,109 *
Michael Severino 43,451 *
Gregory Summe (8) 441,011 *
All Current Executive Officers and Directors as a Group (18 persons) 1,878,386 *
  • Indicates beneficial ownership of less than 1% of the outstanding shares.

(1) Applicable percentage ownership as of March 2, 2026 is based upon 676,105,751 shares of our common stock outstanding. Amounts

include shares subject to stock options that are currently exercisable or are exercisable within 60 days as follows: Mr. Jones

(224,104), Mr. Gourdier (90,251), Mr. Sokenu (62,196), Mr. Walker (57,535), Mr. Stubblefield (5,907,098), and all current directors

and executive officers as a group ( 597,685 ).

(2) Based on information as of June 30, 2025 set for in a Schedule 13G/A dated August 13, 2025, Dodge & Cox reported that it had sole

power to vote 111,093,684 shares and sole power to dispose of 117,433,484 shares. No shared voting or dispositive powers were

reported. The address for Dodge & Cox is 555 California Street, 40 th Floor, San Francisco, CA 94104.

(3) Based on information as of September 30, 2025 set forth in a Schedule 13G/A dated October 17, 2025. BlackRock, Inc. reported that

it had sole power to vote 56,188,076 shares, sole power to dispose of 59,049,575 shares. No shared voting or dispositive powers

were reported. The address for BlackRock, Inc. is 50 Hudson Yards, New York, NY 10001.

(4) Based on information as of December 29, 2023 set forth in a Schedule 13G/A dated February 13, 2024, The Vanguard Group, Inc.

reported that it had sole power to vote 0 shares, sole power to dispose of 63,832,470 shares, shared power to vote 442,323 shares,

and shared power to dispose of 1,512,114 shares. The address for The Vanguard Group, Inc. is 100 Vanguard Blvd., Malvern, PA

19355.

(5) I ncludes (i) 545,500 shares of common stock held by The Stubblefield GST Family Trust, of which Mr. Stubblefield’s wife is the sole

trustee and has voting and investment power over the shares of common stock and (ii) 487,049 shares of common stock held by a

grantor retained annuity trust of which Mr. Stubblefield is the sole trustee .

(6) I ncludes 50,000 shares of common stock held by a trust, of which Mr. Lucier is the sole trustee and has voting and investment power

over the shares of common stock .

(7) I ncludes 350,000 shares of common stock held by a limited liability company, of which Mr. Mehra is the managing member and has

voting and investment power over the shares of common stock .

(8) Includes (i) 400,000 shares of common stock held by a trust, of which Mr. Summe is the sole trustee and has voting and investment

power over the shares of common stock and (ii)18,285 shares of common stock underlying vested restricted stock units, the

settlement of which has been deferred at Mr. Summe’s election pursuant to the non-employee director deferred compensation plan.

41

Stock Ownership Information

Delinquent Section 16(a) Reports

Section 16(a) of the Exchange Act requires our directors, officers and beneficial owners of more than ten percent of our

common stock to file reports with the SEC regarding their ownership of our equity securities and changes in such

ownership. Based solely on our review of electronic filings made with the SEC of such reports and written representations

from our executive officers and directors, we believe that our directors, officers and beneficial owners of more than ten

percent of our common stock complied with their respective filing obligations under Section 16(a) during 2025, except that

one Form 4 for Emmanuel Ligner was filed one day late due to a delay in obtaining EDGAR access codes.

42 2026 Proxy Statement

PROPOSAL NO. 2 Advisory Approval of Named Executive Officer Compensation
The Board of Directors recommends a vote “ FOR ” ITEM 2, to approve, on an advisory basis, the compensation of the Company’s named executive officers, as stated in the above resolution.

The Board of Directors is asking you to approve, on an advisory basis, the executive compensation programs and policies

and the resulting 2025 compensation of our named executive officers disclosed in the Compensation Discussion and

Analysis, the compensation tables, notes and narrative in this Proxy Statement.

Our Board of Directors believes that the compensation of our executive officers is aligned with Avantor’s performance and

stockholder value creation, and appropriately motivates and retains our executives. We believe our executive

compensation program delivers pay that is strongly linked to performance over time.

Because the vote is advisory, the result will not be binding on the Compensation and Human Resources Committee and it

will not affect, limit or augment any existing compensation or awards. However, we value stockholder feedback and the

Compensation and Human Resources Committee will consider the outcome of the vote when designing future

compensation arrangements.

The Board of Directors recommends that you approve the following resolution:

RESOLVED, that the compensation paid to the company’s named executive officers, as disclosed pursuant to Item

402 of Regulation S-K, including the Compensation Discussion and Analysis, compensation tables and narrative

discussion, is hereby APPROVED.

43

PROPOSAL NO. 3 Advisory Vote on the Frequency of Future Advisory Votes on Executive Compensation
The Board of Directors recommends a vote to hold future Say-on-Pay votes every ONE YEAR .

The Board of Directors is asking you to cast an advisory (non-binding) vote on how frequently stockholders should have

an opportunity to vote on an advisory basis to approve the compensation of our Named Executive Officers. We are

required by law to hold an advisory vote on the frequency of Say-on-Pay votes every six years. You may vote to hold the

advisory vote on Say-on-Pay every one, two or three years.

We recognize that the widely adopted standard is to hold Say-on-Pay votes annually. We also acknowledge current

stockholder expectations and preferences regarding having the ability to express their views on the compensation of the

Company’s Named Executive Officers on an annual basis. Accordingly, we are asking stockholders to support a frequency

period of “ONE YEAR” (an annual vote) for future Say-on-Pay votes.

The Board of Directors has determined that seeking advisory approval of named executive officer compensation every

year is the best approach for the Company based on a number of considerations. These considerations include that this

frequency aligns with the interests of stockholders, provides more consistent and direct communication and reflects sound

corporate governance principals.

Votes on the frequency for Say-on-Pay are advisory. Although your vote on this proposal does not bind the Company, the

Board will review the results of the vote and investor feedback and will continue to review the advantages and

disadvantages for each of the frequencies on Say-on-Pay votes regardless of the outcome of the vote.

44 2026 Proxy Statement

Executive Compensation

Compensation Discussion and Analysis

This compensation discussion and analysis (our “CD&A”) provides an overview of our executive compensation philosophy

and the material elements of compensation awarded to, earned by, or paid to our named executive officers (our “NEOs”)

with respect to the year ended December 31, 2025. For 2025, the named executive officers were:

Emmanuel Ligner Director, President and Chief Executive Officer R. Brent Jones Executive Vice President and Chief Financial Officer Corey Walker President, Laboratory Solutions

Benoit Gourdier Executive Vice President, Bioscience Production Claudius Sokenu Executive Vice President, Chief Legal and Compliance Officer

Michael Stubblefield, our former Director, President and Chief Executive Officer, ceased serving in his role effective

August 18, 2025, was also a named executive officer.

This CD&A is divided into three sections:

EXECUTIVE SUMMARY
2025 Financial Highlights CEO Transition Our Executive Compensation Practices Our Compensation Philosophy and Objectives 2025 Compensation Actions for Our Named Executive Officers 2025 Say-On-Pay Vote and Stockholder Engagement
COMPENSATION PHILOSOPHY & OBJECTIVES — HOW WE MAKE COMPENSATION DECISIONS
Role of the Compensation and Human Resources Committee and our Executive Officers Guidance from Independent Compensation Consultant Risk Assessment of Compensation Programs Benchmarking
ELEMENTS OF COMPENSATION — WHAT WE PAY AND WHY
Program Structure and Outcomes Base Salary, Performance-Based Cash Incentive Compensation, Long-Term Incentive Programs, Severance Benefits, Other Components Other Compensation Policies and Practices

45

Executive Compensation

Executive Summary

In 2025, we continued our work with customers in the life sciences and advanced technology industries, providing

mission-critical products, services and technologies to enable scientific progress. We launched the Revival program and

continued our focus on operational efficiency as we position Avantor for growth.

Adjusted EPS* $0.90
2025 Financial Highlights
Adjusted EBITDA* $1.07B Free Cash Flow* $496M
  • For information about these non-GAAP financial measurements, including reconciliations to the most directly comparable GAAP-

based financial measurements, see “Appendix A - Non-GAAP Financial Measurements.”

CEO Transition

In April 2025, Avantor determined to end the employment of Mr. Stubblefield and the parties agreed, pursuant to the

Transition Agreement, to a transition period wherein Mr. Stubblefield would remain employed as the Director, President

and Chief Executive Officer until a successor was appointed and following such appointment, Mr. Stubblefield would

remain a non-executive employee advisor until February 28, 2026, to facilitate a smooth transition.

On July 21, 2025, Avantor announced the appointment of Emmanuel Ligner as President and Chief Executive Officer, and

on August 7, 2025, Avantor announced the appointment of Mr. Ligner to the Board, each effective as of August 18, 2025.

In connection with the appointment, the Company’s UK subsidiary, VWR International Ltd., entered into an employment

agreement (the “Ligner Agreement”) with Mr. Ligner. Pursuant to the Ligner Agreement, Mr. Ligner’s annual base salary

was £775,000 and he was eligible to participate in the Company’s incentive-based annual cash program beginning in

2025, pro-rated based on his hire date, with an annual target bonus opportunity of 150% of his annual base salary. Mr.

Ligner will be eligible to participate in the Company’s long-term incentive program beginning in 2026, with a target annual

grant value of $9,000,000; however, any such awards are not guaranteed and will be determined by the Compensation

and Human Resources Committee of the Company’s Board of Directors.

The Ligner Agreement also provided for a new hire grant of a long-term equity award to Mr. Ligner in the target amount of

$5,000,000, half of the award was granted in the form of restricted stock units and the other half was granted in the form

of premium priced stock options. The awards will vest ratably over three years.

46 2026 Proxy Statement

Executive Compensation

Our Executive Compensation Practices

As part of its annual review of our executive compensation program, the Compensation and Human Resources

Committee confirmed several longstanding Avantor compensation policies and practices and adopted new policies and

practices to further align our executive compensation program with stockholder interests.

Our executive compensation practices include the following, each of which the Compensation and Human Resources

Committee believes reinforce our executive compensation objectives:

WHAT WE HAVE
Significant percentage of target annual compensation is variable and tied to performance Long-term objectives aligned with the creation of stockholder value Market comparison of executive compensation against a relevant peer group Robust stock ownership guidelines Use of an independent compensation consultant reporting directly to the Committee Compensation recovery “clawback” policy for our annual cash-based incentive and all equity-based long-term incentive programs, including time- based equity awards A parallel Dodd-Frank compliant compensation recovery “clawback” policy applicable to current and former executive officers Regular engagement with our stockholders and implementation of enhancements based on feedback received “Double-trigger” change-in-control equity vesting
WHAT WE DON’T HAVE
No hedging or short sales of Company stock, or pledging of Company stock No option grants below 100% fair market value No excessive cash severance benefits upon a change of control No excessive perquisites or benefits to executives No repricing of underwater stock options No tax gross-ups of perquisites or 280G excise taxes (except as applicable to management employees generally in connection with relocation or expatriate assignments) No payment of unearned dividends on unvested equity

47

Executive Compensation

Compensation Philosophy & Objectives

Each year, our Compensation and Human Resources Committee thoroughly reviews our executive compensation

program with guidance from its independent compensation consultant, FW Cook. We believe that pursuing the following

objectives has helped us compete for talent.

Attract and retain talent Provide a total compensation program that enables the Company to attract, motivate, retain and reward high-performing execution-oriented executives who have the ability to contribute to our success, and encourage management to place its primary focus on strategic planning and financial and operational priorities to ensure the achievement of our global strategy.
Pay for performance Support a “pay-for-performance” orientation to provide differentiated rewards for strong financial, operating and individual performance, including the use of performance-based cash and equity incentive compensation to encourage the achievement of short-term and long-term financial and operational objectives.
Market-competitive pay Align the interests of management with those of our other stockholders by providing an incentive for, and rewarding, the attainment of objectives that also benefit our stockholders.

Summary of 2025 Compensation Actions for Our Named

Executive Officers

Consistent with our executive compensation philosophies and objectives, in establishing 2025 compensation for our

named executive officers, the Compensation and Human Resources Committee considered each named executive

officer’s prior performance, compensation levels paid to similarly situated officers at the Company, market data and input

from the Compensation and Human Resources Committee’s independent compensation consultant, FW Cook. For 2025,

the Compensation and Human Resources Committee made the following material decisions with respect to the

compensation of our named executive officers:

refined our compensation peer group that provides a robust sample size and alignment between Avantor and median

size demographics;

compared our executive officers to our compensation peer group and publicly available global salary surveys for

organizations of similar size and revenue;

leveraged an additional peer group of competitive industry peers as reference for compensation plan designs and

trends comparisons, not pay levels;

maintained our cash-based incentive compensation plan, inclusive of segment goals for our business leaders and

individual objectives for all executive officers with a focus on a combination of performance measures that align closely

with those that are used by management to set business goals and evaluate our financial results;

granted annual equity awards to each of the executive officers after considering our compensation philosophy and the

assessment of the executive officer’s expected future contributions, maintaining the weight ing of performance stock

units at one-half with the remainder of the award being made in a mix of stock options and restricted stock units;

granted one-time special equity awards to each of the executive officers to incentivize the leadership team to remain

with the Company to provide business continuity through the CEO transition; and

established an executive severance and change in control plan applicable to all U.S. based executive officers

transitioning severance provisions from individual employment agreements to align severance benefits to executive job

levels.

48 2026 Proxy Statement

Executive Compensation

2025 Say-On-Pay Vote and Stockholder Engagement

We received 87% stockholder support on our 2025 Say-on-Pay proposal, along with support from the major stockholder

advisory firms. While pleased with these results, our Compensation and Human Resources Committee and members of

management believe ongoing dialogue with stockholders regarding executive compensation is valuable.

In 2025, we continued to communicate with many of our largest stockholders to review our compensation philosophy and

the specific features of our compensation program. The feedback we received included the following key themes:

WHAT WE HEARD
• Interest in the Board’s evolving mix of skills, experience and leadership aligned to Company strategy • Emphasis on the importance of leadership continuity, succession planning and operational execution • Highlighted the need to retain key executives to ensure stability and execution during the CEO transition • Desire for clear accountability and pay outcomes aligned with performance, including underperformance • Visibility to key industry competitors in the peer group
WHAT WE DID
Effective for 2025: Refreshed the Board with three new independent directors; bringing deep global leadership across healthcare, life sciences, finance, strategy, and capital allocation Appointed a new CEO with a proven track record and strengthened the executive leadership team, including the COO role Implemented a new executive severance and change in control plan aligned to the market, with “double-trigger” change-in-control vesting provisions, replacing individual agreements Granted retention equity awards with two-year cliff vesting to support leadership continuity Reinforced pay-for-performance alignment through variable compensation design and the use of at-risk incentives. Maintained a reference group of additional industry competitors to monitor program designs and trends comparisons; not used for determining pay levels

49

Executive Compensation

Compensation Philosophy & Objectives - How We

Make Compensation Decisions

We strive to offer an executive compensation program that enables us to attract, motivate, reward and retain high-

performing executives who are capable of creating and sustaining value for our stockholders over the long term. In

addition, the executive compensation program is designed to provide a fair and competitive compensation opportunity that

appropriately rewards executives for their contributions to our success. We believe that it is important to reinforce a

results-oriented management culture focusing on our level of earnings; the achievement of both short-term and long-term

goals and objectives, including the acceleration of our global growth strategy; and individual performance objectives. Pay

received by executives is intended to be commensurate with organizational performance, individual performance, and

labor market conditions.

Role of the Compensation and Human Resources Committee

and our Executive Officers

Our Compensation and Human Resources Committee recommended the 2025 compensation of both our former and

current Chief Executive Officers, which was ultimately approved by the independent members of our Board of Directors.

The Compensation and Human Resources Committee also determined the compensation of each of our other named

executive officers.

In recommending the compensation of our Chief Executive Officer, the Compensation and Human Resources Committee

takes into account its review of the Chief Executive Officer’s performance and any other factors it deems relevant. In

setting the compensation of our other executive officers, the Compensation and Human Resources Committee takes into

account the Chief Executive Officer’s review of each executive officer’s performance and his recommendations with

respect to their compensation. The Compensation and Human Resources Committee’s responsibilities regarding

executive compensation are further described above under “Corporate Governance—Committees of the Board.”

Guidance from Independent Compensation Consultant

FW Cook provides executive compensation consulting services to the Compensation and Human Resources Committee.

In 2025, FW Cook provided services related to the review of the compensation program, including an evaluation of peer

group and other global salary survey compensation data, performance goals in our performance-based cash incentive

plans, and equity award levels under our long-term incentive plan. FW Cook also provided assistance with this CD&A and

conducted a risk assessment of our 2025 compensation programs and a review of trends in executive compensation. FW

Cook did not provide any other services to the Company in 2025.

FW Cook is retained by and reports to the Compensation and Human Resources Committee and, at the request of the

Compensation and Human Resources Committee, participates in committee meetings. The Compensation and Human

Resources Committee reviewed the independence of FW Cook under NYSE and SEC rules and concluded that the work

of FW Cook has not raised any conflict of interest.

Risk Assessment of Compensation Programs

As part of its oversight responsibility, the Compensation and Human Resources Committee considers our risk profile and

seeks to maintain a balanced compensation program that does not incentivize undue or inappropriate risks that are

reasonably likely to have a material adverse effect on Avantor.

At the request of the Compensation and Human Resources Committee , FW Cook conducted an assessment of our 2025

compensation programs and concluded that our compensation policies and practices do not create risks that are

reasonably likely to have a material adverse effect on the Company. This risk assessment included reviewing the design

and operation of our compensation programs, identifying and evaluating situations or compensation elements that could

raise more significant risks, and evaluating other controls and processes designed to identify and manage risk. The

Compensation and Human Resources Committee reviewed this risk assessment and concurred with FW Cook’s

conclusion.

50 2026 Proxy Statement

Executive Compensation

Benchmarking

We review external market practices for all compensation elements to ensure that our compensation levels and program

design will effectively attract, motivate, retain and reward talented executives. In the aggregate, our named executive

officer group is compensated at the market median for each compensation element. However, compensation for individual

executives may vary from the median due to the executives’ unique skills, experience, or other qualities.

Each year our Compensation and Human Resources Committee, with assistance from FW Cook, reviews and evaluates

the market landscape and composition of our peer group to ensure it remains appropriate. The Compensation and Human

Resources Committee primarily identifies companies that have business models similar to ours, with a market

capitalization and revenues of generally between 0.33x and 3.0x ours, that represent an appropriate cross section of the

industries and geographies in which we are engaged or serve (primarily companies in the biopharma, healthcare, and life

sciences industries). After this evaluation in 2025, two companies, DENTSPLY Sirona, Inc. and Vertex Pharmaceuticals,

Inc. were removed from the peer group as falling outside of our market capitalization parameters, Boston Scientific

C orporation was moved to our Reference Group, and Catalent, Inc. was removed following its acquisition by Novo Holdings:

Agilent Technologies, Inc.

Baxter International, Inc.

Biogen Inc.

Bio-Rad Laboratories, Inc.

Bruker Corporation

Charles River Laboratories

International, Inc.

Edwards Lifesciences

Hologic, Inc.

Illumina, Inc.

IQVIA Holdings Inc.

Laboratory Corp. of America

Mettler-Toledo International Inc

Quest Diagnostics Inc.

Revvity, Inc.

Waters Corporation

Zimmer Biomet Holdings, Inc.

At the time of the Compensation and Human Resources Committee ’s compensation review, relative to its peer group of

companies, Avantor was at the 61st percentile for revenue, 38th percentile for EBITDA, and 17th percentile for market

capitalization.

The Compensation and Human Resources Committee utilizes an additional comparator group (“Reference

Group”) consisting of ten industry competitor companies as reference for program designs and trends. The Reference

Group is not used to benchmark or set pay levels of executives.

AbbVie Inc.

Amgen Inc.

Becton, Dickinson & Co.

Boston Scientific Corporation

Cencora, Inc.

Danaher Corporation

Honeywell International Inc.

McKesson Corporation

Stryker Corporation

Thermo Fisher Scientific Inc.

51

Executive Compensation

Elements of Compensation - What We Pay and Why

Each year the Compensation and Human Resources Committee undertakes a comprehensive review of our executive

compensation program. The principal components of our executive compensation program are base salary, an annual

cash incentive and long-term equity incentives. We also provide market competitive employee benefits and a limited

number of perquisites.

Program Structure and Outcomes

The following table provides a summary of the compensation program and performance outcomes for our named

executive officers in 2025.

Component Short-Term Incentives Long-Term Incentives
Proportion of Total Target Pay CEO
Other NEOs
Structure/ Metrics/ Features Base salary aligned with others in our peer group and broader market Structure: 100% performance-based cash incentive Features: • Rigorous pre-set goals • Awards capped at 200% of target Metrics & Weightings: Ligner, Jones, Sokenu • 40% Enterprise Revenue • 20% Enterprise Operating Income • 10% Free Cash Flow • 5% GHG Emissions Reduction • 5% Inclusion Index • 20% Individual Strategic Goals Walker, Gourdier • 20% Enterprise Revenue • 20% Segment (LSS/BPS) Revenue • 10% Enterprise Operating Income • 10% Segment (LSS/BPS) Operating Income* • 10% Free Cash Flow • 5% GHG Emissions Reduction • 5% Inclusion Index • 20% Individual Strategic Goals Structure: • 50% three-year performance stock units • 25% stock options with three- year ratable vesting • 25% restricted stock units with three-year ratable vesting Features: • Rigorous pre-set goals Metrics & Weightings (for performance stock units): • 5 0% Adjusted EPS Growth • 50% total stock return (“TSR”) relative to comparator grou p Ligner Sign-on Structure: • 50% premium-priced stock options with three-year ratable vesting • 50% restricted stock units with three-year ratable vesting
2025 Performance Outcomes Average base salary increase of 1% • Enterprise and segment revenue achieved between threshold and target • Enterprise and segment adjusted operating income achieved below threshold • Free cash flow achieved between threshold and target • GHG emissions reduction and inclusion index achieved between target and maximum • Individual strategic goal achievement varied by executive 20% Negative Discretion Applied • For the 2023 performance stock units granted for the period of 2023-2025: • Cumulative Adjusted EPS metric was achieved below threshold (0% payout) • TSR metric was achieved below threshold (0% payout)
  • For information about these non-GAAP financial measurements, including reconciliations to the most directly comparable GAAP-

based financial measurements, see “Appendix A - Non-GAAP Financial Measurements.”

52 2026 Proxy Statement

Executive Compensation

In order to provide a clearer view of our 2025 compensation program, the charts below demonstrate how our named

executive officer compensation is designed to emphasize target total direct compensation that is variable, at-risk and long-

term oriented.

CEO (1) AVERAGE OTHER NEOs

(1) Reflects annualized base salary, target short-term incentive and 2026 target long-term incentive for Emmanuel Ligner.

Base Salary

We believe it is important to provide a competitive fixed level of pay to attract and retain experienced and successful

executives. In determining the amount of base salary that each named executive officer receives, we look to the

executive’s current compensation, tenure and performance, any change in the executive’s position or responsibilities, and

the complexity and scope of the executive’s position as compared to those of other executives within the company and in

similar positions at companies in our peer group. The Compensation and Human Resources Committee reviews base

salaries periodically and may adjust them from time to time pursuant to such review. In February 2025, the Compensation

and Human Resources Committee reviewed and set the base salaries shown below.

Name Base Salary (12/31/2024) ($) Base Salary (12/31/2025) ($) (1) Year over Year Change (%)
Emmanuel Ligner 1,022,016 (2) 0.0
R. Brent Jones 635,000 660,000 3.9
Corey Walker 700,000 700,000 0.0
Benoit Gourdier 550,000 550,000 0.0
Claudius Sokenu 550,000 550,000 0.0

(1) No base salary increase was provided to Mr. Stubblefield in 2025.

(2) Converted from British Pound Sterling to U.S dollars using the average of the monthly average exchange rates for 2025 (1.31873).

53

Executive Compensation

Performance-Based Cash Incentive Compensation

Our annual cash bonus program, the Incentive Compensation Plan (the “ICP”), is designed to motivate executive officers

to focus on strategic business results and initiatives and reward them for their results and achievements. The ICP provides

for a bonus opportunity based on achievement of company-wide financial targets, corporate and strategic initiatives, and

individual performance.

Target Bonus Opportunities

Bonus opportunities under the ICP are reviewed annually by the Compensation and Human Resources Committee . The

Compensation and Human Resources Committee established the following target bonus opportunities for the named

executive officers for 2025:

Executive 2025 Base Salary Target Bonus (%) Target Bonus ($)
Emmanuel Ligner (1) $ 1,022,016 150% $ 1,533,024
R. Brent Jones $ 660,000 80% $ 528,000
Corey Walker $ 700,000 80% $ 560,000
Benoit Gourdier $ 550,000 80% $ 440,000
Claudius Sokenu $ 550,000 75% $ 412,500

(1) Converted from British Pound Sterling to U.S dollars using the average of the monthly average exchange rates for 2025 (1.31873).

Final payouts for each named executive officer are determined by multiplying the executive’s target bonus by (i) the

weighted funding percentage fixed by the Compensation and Human Resources Committee at the end of the year based

on the Company’s achievement with respect to the performance metrics described below, and (ii) the weighted individual

funding percentage fixed by the Compensation and Human Resources Committee based on the executive’s achievements

with respect to his or her individual strategic goals.

Performance Metrics and Bonus Calculation

For 2025, our Board of Directors and Compensation and Human Resources Committee established the following ICP

framework, which directly aligns with the Company’s priorities to drive growth, improve operational excellence, and

achieve incremental corporate impact targets.

Financial Performance

Metric Weighting Why This Metric Is Important
Revenue 40% Revenue, calculated on a constant currency basis, is the key metric used to assess performance of our business over the short term and is a common measure to compare results across companies in the industry.
Constant Currency Adjusted Operating Income 20% Constant Currency Adjusted Operating Income is the key metric used to measure growth and the profitability of our business.
Free Cash Flow 10% Free Cash Flow is a key metric used to measure our ability to generate cash for use in financing or investing activities.

54 2026 Proxy Statement

Executive Compensation

Corporate and Strategic Initiatives

Metric Weighting Why This Metric Is Important
Reduction in Greenhouse Gas Emissions 5% Reduction in Greenhouse Gas Emissions (GHG) is a key metric indicating our efforts to reduce current emissions and offset those generated from expansion and organizational growth.
Associate Experience 5% Inclusion Index is a key metric tied to Avantor's Enterprise Priority of Enhancing the Associate Experience. As measured by the People Pulse survey, the Inclusion Index reflects associates' sense of feeling valued as an individual and sentiments on Avantor's demonstrated commitment to belonging for all.

Individual Strategic Goals

Metric Weighting Why This Metric Is Important
Individual Strategic Goals 20% Individual Strategic Goals are tied to a set of individually tailored objectives to drive enterprise growth and operational excellence and enhance the associate experience.

As described below, each year, the Compensation and Human Resources Committee establishes performance ranges for

our financial goals and our corporate and strategic initiatives based on the best available information and determines

appropriate threshold, target, and maximum performance levels. Payouts on these metrics start at 50% for threshold

performance and graduate on a straight-line basis to 100% for target performance and 200% for maximum performance. If

threshold is not met for a particular metric, that portion of the plan is not funded. Payouts for the individual strategic

performance component also can reach a maximum of 200% of the individual bonus target. The overall funding of the ICP

pool may not exceed 200%. The following tables illustrate the target bonus calculation formulas for 2025.

The Compensation and Human Resources Committee has discretion to modify all or any portion of any award as it deems

necessary or appropriate.

Messrs. Ligner, Jones, Sokenu and Stubblefield

CASH BONUS TARGET

PERFORMANCE FACTORS

CASH BONUS

Company Enterprise

performance

(expressed as a percentage

of target bonus)

(80%)

Individual Strategic

performance

(expressed as a percentage

of target bonus)

(20%)

Target bonus

opportunity

(expressed as a

percentage of base

salary)

Annual cash

bonus award

Base

Salary (1)

75% to 150%

target bonus based

on role (2)

0%-200%

0%-200%

(1) Base salary reflects eligible base salary earnings used for incentive compensation calculations.

(2) Mr. Stubblefield’s target bonus opportunity was 165%.

55

Executive Compensation

Messrs. Walker and Gourdier

CASH BONUS TARGET

PERFORMANCE FACTORS

CASH BONUS

Company

Enterprise

performance

(expressed as a

percentage of

target bonus)

(50%)

Company

Segment

performance

(expressed as a

percentage

of target bonus)

(30%)

Individual

Strategic

Goals

(expressed as a

percentage

of target bonus)

(20%)

Target bonus

opportunity

(expressed as a

percentage of base

salary)

Annual cash

bonus award

Base

Salary (1)

80%

target bonus

0%-200%

0%-200%

(1) Base salary reflects eligible base salary earnings used for incentive compensation calculations

Performance Goals and Results

Each year, the Compensation and Human Resources Committee establishes threshold, target, and maximum

performance levels for financial goals using a structured, data‑driven process informed by internal planning assumptions,

external market conditions, and investor expectations. For 2025, the target revenue goal was set modestly below 2024

actual results, however this was driven by the impact of our clinical services divestiture and planned foreign exchange

headwinds. When adjusted for these two factors the target required approximately two percent organic year‑over‑year

growth. The Compensation and Human Resources Committee viewed this goal as appropriately demanding, as it required

continued execution and market share performance rather than reliance on prior‑year momentum, and determined that

achievement was not assured at the time the goal was established. Consistent with the Company’s pay‑for‑performance

philosophy, the 2025 revenue target was aligned with the midpoint of the Company’s full‑year financial guidance

communicated to the investment community in early 2025.

For 2025, the target free cash flow goal was set at approximately $93 million below 2024 actual results, reflecting the

Compensation and Human Resources Committee’s assessment that free cash flow performance in 2024 benefitted from

exceptional, non‑recurring factors and was not expected to be replicated on a normalized basis. The Compensation and

Human Resources Committee viewed the 2025 target as appropriately rigorous, as it required continued strong execution

on earnings, working capital discipline, and capital efficiency without reliance on prior‑year one‑time benefits, and

determined that achievement was not assured at the time the goal was established. The table below provides threshold,

target and maximum financial targets under the 2025 ICP, as well as actual results.

Enterprise : Ligner, Jones, Sokenu, Stubblefield

(dollars in millions) Weighting Threshold Target Stretch Actual Achievement as a percent of target Weighted payout percentage
Revenue (2) 40% $6,136.5 $6,634.0 $7,131.6 $6,323.0 95% 69% (1)
Constant Currency Adjusted Operating Income (2) 20% $979.1 $1,119.0 $1,258.9 $939.0 84% —%
Free Cash Flow (3) 10% $540.0 $675.0 $810.0 $599.0 89% 72% (1)
Greenhouse Gas Emissions (4) 5% 8% 9% 10% 10% 108% 154%
Inclusion Index (5) 5% 7.5 7.9 8.3 8.2 104% 175%
Company funding percentage 63.9% (1)

56 2026 Proxy Statement

Executive Compensation

Enterprise / Laboratory Solutions Segment: Walker

(dollars in millions) Weighting Threshold Target Stretch Actual Achievement as a percent of target Weighted payout percentage
Revenue (2) 20% $6,136.5 $6,634.0 $7,131.6 $6,323.0 95% 69%
LSS Segment Revenue 20% $4,064.0 $4,394.0 $4,724.0 $4,218.0 96% 73%
Constant Currency Adjusted Operating Income (2) 10% $979.1 $1,119.0 $1,258.9 $939.0 84% —%
LSS Segment Adjusted Operating Income (2) 10% $522.0 $597.0 $671.0 $487.0 82% —%
Free Cash Flow (3) 10% $540.0 $675.0 $810.0 $599.0 89% 72%
Greenhouse Gas Emissions (4) 5% 8% 9% 10% 10% 108% 154%
Inclusion Index (5) 5% 7.5 7.9 8.3 8.2 104% 175%
Company / Segment funding percentage 65.1%

Enterprise / Bioscience Production Segment: Gourdier

(dollars in millions) Weighting Threshold Target Stretch Actual Achievement as a percent of target Weighted payout percentage
Revenue (2) 20% $6,136.5 $6,634.0 $7,131.6 $6,323.0 95% 69%
BPS Segment Revenue 20% $2,072.0 $2,240.0 $2,408.0 $2,105.0 94% 60%
Constant Currency Adjusted Operating Income (2) 10% $979.1 $1,119.0 $1,258.9 $939.0 84% —%
BPS Segment Adjusted Operating Income (2) 10% $530.0 $605.0 $681.0 $515.0 85% —%
Free Cash Flow (3) 10% $540.0 $675.0 $810.0 $599.0 89% 72%
Greenhouse Gas Emissions (4) 5% 8% 9% 10% 10% 108% 154%
Inclusion Index (5) 5% 7.5 7.9 8.3 8.2 104% 175%
Company / Segment funding percentage 61.7%

(1) Payout for Mr. Stubblefield starts at 61% funding level for threshold performance per his employment agreement (50% for other

executives), resulting in a payout of 75% for Revenue, 0% for Currency Adjusted Operating Income, 78% for Free Cash Flow and

Company funding percentage of 68%.

(2) Constant currency measures are calculated using fixed foreign currency exchange rates. These rates are generally established at the

beginning of the year in connection with the development of the operating plan for the year.

(3) Free Cash Flow is defined as cash flows from operating activities, less capital expenditures, plus direct transaction costs and income

taxes paid related to acquisitions and divestitures (as applicable) in the period and excludes the cash costs associated with our cost

transformation initiative.

(4) The target greenhouse gas emissions goal represents the reduction in 2025 needed to achieve the Company’s 2030 reduction goal

of 50%.

(5) The inclusion index represents employee sentiment scores as reported in our people pulse surveys.

57

Executive Compensation

Individual Strategic Goals

Name Strategic Goals
Emmanuel Ligner Mr. Ligner’s goals included (i) establishing and communicating a clear strategic vision for Avantor; (ii) engaging with shareholders, customers, suppliers, and regulators; (iii) assessing the Company’s organizational health, including culture, talent, and operational effectiveness; and (iv) driving early momentum by working with the leadership team to enhance operating mechanisms and accountability.
R. Brent Jones Mr. Jones’s goals included (i) financial leadership during a period of market volatility, including actions to support cash generation and refinancing initiatives; (ii) progress toward cost transformation initiatives and realization of run rate savings that reinforced operational discipline; (iii) continued development of financial leadership capabilities across the organization; and (iv) the provision of strategic guidance to the Board on business restructuring efforts to support organizational stability and disciplined execution for long term value creation.
Corey Walker Mr. Walker’s goals included (i) stabilization and repositioning of the Laboratory Solutions business; (ii) progress in cost control, organizational engagement, and strategic planning; (iii) implementation of operating changes to increase accountability, collaboration, and future growth; and (iv) positive customer positioning for continued transformation & innovation.
Benoit Gourdier Mr. Gourdier’s goals included (i) leadership of Bioscience Production and the implementation of a new business unit structure; (ii) the launch of multiple new products; (iii) delivery of cost control and manufacturing digitization initiatives; and (iv) refinement of long-term strategies to position the segment for future growth.
Claudius Sokenu Mr. Sokenu’s goals included (i) enhancement of board governance and compliance; (ii) consolidation of outside counsel spend and establishment of a Legal Operations office; (iii) restructuring of the legal organization; supporting talent stability and organizational performance; and (iv) provision of strategic guidance during major company transitions.

58 2026 Proxy Statement

Executive Compensation

Final 2025 ICP Payouts

The Compensation and Human Resources Committee approved the Company funding percentage under the 2025 ICP at

63.9% for Enterprise, 65.1% for Enterprise/Laboratory Solutions Segment and 61.7% for Enterprise/Bioscience Production

Segment. In exercising its discretion and taking into account overall company performance, the Compensation and

Human Resources Committee further determined to apply a 20% downward adjustment to overall payouts to reflect its

holistic assessment of Company performance. On this basis, annual bonus awards for each of the named executive

officers on account of 2025 performance are set forth in the table below.

Name Base Salary (12/31/2025) ($) Target (%) Target Annual Incentive ($) Performance Factor (1) (%) Negative Discretion (%) 2025 ICP bonus ($)
E mmanuel L igner (2) 386,681 150 580,022 71.1 (20) 330,038
R. Brent Jones 653,269 80 522,615 65.1 (20) 272,288
Corey Walker 700,000 80 560,000 72.0 (20) 322,755
Benoit Gourdier 550,000 80 440,000 61.3 (20) 215,921
Claudius Sokenu 550,000 75 412,500 63.1 (20) 208,317
Michael Stubblefield (3) 1,140,000 165 1,881,000 68.0 (20) 1,022,795

(1) Represents a blended average of the enterprise, segment (if applicable) and individual performance factors. Individual performance

factors were applied as follows: Mr. Ligner (100%), Mr. Jones (70%), Mr. Walker (100%), Mr. Gourdier (60%), and Mr. Sokenu (60%).

(2) Converted from British Pounds Sterling to U.S. dollars based on the exchange rate as of the close of business on December 31, 2025

(1.3444).

(3) Per the terms of his Transition Agreement, Mr. Stubblefield’s individual funding factor is equal to the corporate funding factor of 67.97.

Additional details regarding the dollar value of threshold, target and maximum bonus payout opportunities for 2025 are

provided under “Executive compensation tables — Grants of plan-based awards.”

Long–Term Incentive Programs

Our Compensation and Human Resources Committee believes that equity awards are a key component of our executive

compensation program because they help us attract, motivate and retain executive talent.

LONG-TERM INCENTIVE

PSUs RSUs Stock Options

For 2025, the allocation of the annual equity award for our executive officers was 50% in performance stock units, 25% in

stock options and 25% in restricted stock units. This mix provides an incentive to achieve favorable long-term results at a

reasonable cost to the Company.

59

Executive Compensation

In connection with his hire, Mr. Ligner was granted a long-term equity award consisting of 50% premium-priced stock

options and 50% restricted stock units. Beginning in 2026, Mr. Ligner will be eligible to participate in the Company’s long-

term incentive program, with the mix of equity awards aligned with that of the Company’s other executive officers.

These awards represented approximately 35 % (excluding the award to our former CEO Michael Stubblefield) of the t otal

equity incentives granted to manage ment and other employees in 2025. We believe that it was appropriate to award this

percentage to our named executive officers because they are in the best position to drive our future results and implement

our long-term business strategy. This percentage also reflects market-based equity grant levels.

Stock Options and Restricted Stock Units

Stock options and restricted stock units vest in equal installments on the first three anniversaries of the grant date, subject

to the named executive officer’s continued employment through the applicable vesting date.

The exercise price for the stock options granted in February 2025 is $17.49, the closing price of our common stock on the

grant date. The exercise price for the premium-priced stock options granted to Mr. Ligner on August 18, 2025 is $14.04,

which represented a 10% premium to the closing price of $12.76 on the grant date. The Compensation and Human

Resources Committee believes that stock options are effective at motivating executives to pursue Avantor’s long-term

goals because the options only have value if our stock price appreciates after the grant date. The options granted in 2025

will remain exercisable until the 10th anniversary of the grant date.

Performance Stock Units

The performance stock units granted in 2025 have a three-year performance period that began on the first day of 2025

and will end on the last day of 2027. Performance stock units may be earned based on achievement with respect to two

equally weighted performance metrics compared to performance goals approved by the Compensation and Human

Resources Committee at the time of grant.

Named executive officers have the opportunity to earn a payout of between 0% and 200% of their target performance

stock unit awards. If threshold performance for one of the metrics is not attained, there will not be any payout based on

that metric. Threshold performance for each metric will result in a share payout equal to 50% of the target award. Payouts

will increase on a straight-line basis to 100% for target performance and 200% for attaining the maximum goal.

One-half of the performance stock units will be measured against Avantor’s TSR relative to our comparator group, the

S&P 500 Health Care Index, which includes compensation peers.

2025–2027 Relative Total Shareholder Return

Metric Weighting Threshold Target Maximum
3-yr Relative Total Stockholder Return (1) 50% 25 th %ile 50 th %ile 90 th %ile

(1) TSR percentile performance determined by company ranking and each peer group member according to its respective TSR for the

performance period, from minimum to maximum, with the lowest TSR turn being assigned a rank of one. The Company’s percentile

rank is calculated by dividing the Company’s rank by the total number of comparator group members (including the Company). TSR

is the result of dividing (x) the entity’s ending price minus the beginning price, by (y) the beginning price. Dividends are assumed to

be reinvested as of the ex-dividend date in the calculation.

The other half of the performance stock units will be earned, or not, based on Avantor’s adjusted EPS growth. Adjusted

EPS growth targets are fixed at the time of the grant and measured separately for each fiscal year in the three-year

performance period. The performance targets for the second and third years are based on actual adjusted EPS

performance in the prior year plus a targeted growth rate. The average performance multiplier, which is the numeric

average of the performance multipliers earned with respect to each fiscal year in the three-year performance period, will

be used to calculate the number of units earned. The specific goals for the adjusted EPS growth component of the

performance stock unit awards are confidential, but consistent with our long-range plan.

60 2026 Proxy Statement

Executive Compensation

The Compensation and Human Resources Committee believes that the relative TSR relative and average adjusted EPS

goals described above are challenging and difficult to achieve, but attainable with significant skill and effort on the part of

our executive leadership team.

Additional details regarding the equity awards described above are provided under “Executive Compensation Tables —

Outstanding equity awards at December 31, 2025.”

2023 Performance Stock Unit Payouts

Messrs. Jones, Sokenu and Stubblefield received performance shares for the three-year performance period spanning

fiscal year 2023 through fiscal year 2025. In February 2026, the Compensation and Human Resource Committee

approved the performance results and related payouts of these performance stock units based on achievement of three-

year cumulative adjusted EPS and three-year relative total stockholder return versus a defined group of peers.

Based on our performance, and the respective weighting of each performance metric, no shares were earned for the fiscal

year 2023 through fiscal year 2025 performance period.

Metric Weighting Threshold Target Maximum Actual Achievement as a percentage of target
3-yr Cumulative Adjusted EPS (1) 50% $ 4.39 $ 4.88 $ 5.37 $ 2.98 0%
3-yr Relative Total Stockholder Return (2) 50% 25 th %ile 50 th %ile 90 th %ile 13 th %ile 0%
Company funding percentage 0%

(1) Cumulative Adjusted EPS is the result of dividing (x) the sum of the Adjusted Net Income for each fiscal year during the Performance

Period and (y) the Share Count.

(2) TSR percentile performance determined by company ranking and each peer group member according to its respective TSR for the

performance period, from minimum to maximum, with the lowest TSR turn being assigned a rank of one. The Company’s percentile

rank is calculated by dividing the Company’s rank by the total number of comparator group members (including the Company). TSR

is the result of dividing (x) the entity’s ending price minus the beginning price, by (y) the beginning price. Dividends are assumed to

be reinvested as of the ex-dividend date in the calculation. No dividends have been paid on forfeited performance stock units.

Retention Grants for Named Executive Officers

In May 2025, following stockholder engagement and in consultation with FW Cook, the Compensation and Human

Resources Committee granted one‑time long‑term incentive retention awards to the named executive officers to support

leadership stability and continuity during the CEO transition. Stockholder feedback emphasized the importance of

retaining key executive talent during this period, and the Compensation and Human Resources Committee determined

that executive continuity was critical to maintaining operational momentum and protecting long‑term stockholder value.

The retention awards are granted in the form of restricted stock units that will cliff vest on the second anniversary of the

date of grant, subject to the named executive officer remaining employed through the vesting date. Upon the named

executive officer’s termination of service, any then-unvested portion of the award will be automatically forfeited, except

that in the case of a termination of service due to death, disability or an involuntary termination without cause, any

unvested restricted stock units will vest. The Compensation and Human Resources Committee did not include additional

performance conditions in these awards, as the primary objective was retention during the transition period.

In determining the retention award amounts, the Compensation and Human Resources Committee considered the

competitive market for executive talent, each executive officer’s role and expected contribution during the transition

period, and the importance of retaining experienced leadership. The awards are subject to forfeiture upon voluntary

termination to align executive outcomes with stockholder interests.

The Compensation and Human Resources Committee does not view these awards as a recurring element of the

Company’s compensation program and expects that similar one‑time awards will be granted only in extraordinary

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Executive Compensation

circumstances, such as significant leadership transitions. The table below summarizes the value and key terms of these

awards:

Name Target Award Value ($) Award Type Grant Date Vesting Number of RSUs (1)
R. Brent Jones 2,000,000 RSU 5/9/2025 2-year cliff 162,866
Corey Walker 2,000,000 RSU 5/9/2025 2-year cliff 162,866
Benoit Gourdier 2,000,000 RSU 5/9/2025 2-year cliff 162,866
Claudius Sokenu 1,500,000 RSU 5/9/2025 2-year cliff 122,149

(3) RSUs granted on May 9, 2025 were calculated using the closing price of our common stock on May 8, 2025 ($12.28).

Severance Benefits

Executive Severance and Change in Control Plan. In 2025, the Company established the Executive Severance and

Change in Control Plan (the “Severance Plan”) applicable to its U.S.-based executive officers, transitioning from

employment agreement based severance provisions. Under the terms of the Severance Plan, severance benefits are

fixed based on job level with the severance formula varying depending on whether the event that precipitates the payment

occurs as a result of a change in control.

The Severance Plan also provides for an enhanced severance benefit for a defined period through May 2027. During this

period, unvested equity will continue to vest for 12 months post-termination. After May 2027, unvested equity will forfeit

upon termination. Our Compensation and Human Resources Committee believes that this enhancement is appropriate in

light of the CEO transition and is designed to provide competitive yet disciplined severance protections that are aligned

with prevailing market practices for similarly situated companies and the interests of shareholders.

Severance arrangements . For executive officers based outside the United States, including Mr. Ligner, individual

employment arrangements continue to provide for payments and other benefits in connection with certain qualifying

terminations of employment. Our Compensation and Human Resources Committee believes that these severance

benefits: (i) help secure the continued employment and dedication of our named executive officers; (ii) enhance our value

to a potential acquirer because our named executive officers have non-competition, non-solicitation and confidentiality

provisions that apply after any termination of employment, including after a change in control; and (iii) are important as a

recruitment and retention device, as many of the companies with which we compete for executive talent have similar

agreements in place for their senior management.

For more information regarding the severance benefits for each of our named executive officers, including a quantification

of benefits that would have been received by each named executive officer who is currently employed by the Company

had their employment terminated on December 31, 2025, the last business day of 2025, see “Executive Compensation —

Executive Compensation Tables — Termination and Change in Control Arrangements.”

Other Components of 2025 Executive Compensation Program

Retirement and Other Related Benefits

Savings plan. We sponsor the Avantor Retirement Savings 401(k) Plan and Trust (the “Savings Plan”), which is a tax-

qualified retirement savings plan available to all U.S.-based employees, including our U.S.-based named executive

officers. Employees can contribute, on a before-tax basis or on a Roth after-tax basis, up to 99% of their earnings to the

Savings Plan, up to the limit prescribed by the Internal Revenue Service. We match 100% of the first four percent of

contributions to the Savings Plan and we may make nonelective contributions to the Savings Plan for eligible employees,

subject to earnings limitations and other limits under applicable federal income tax rules. Company matching and

nonelective contributions to the Savings Plan are fully vested upon contribution. Mr. Gourdier elected not to contribute to

the plan in 2025. Our contributions to the named executive officers’ respective Savings Plan accounts is reflected in the

column “All Other Compensation” of the Summary Compensation Table.

62 2026 Proxy Statement

Executive Compensation

UK savings plan . Our United Kingdom subsidiary, VWR International Ltd., sponsors the VWR International Group

Flexible Retirement Plan, which is a defined contribution workplace pension scheme (the “UK Savings Plan”). Each year,

contributions to the plan are made by each of the individual participants in the plan and the employer, with the employer

portion equal to 8% of the participants base salary. Mr. Ligner was eligible to participate in the UK Savings Plan in 2025

and our contribution to his UK Savings Plan account is reflected in the column “All Other Compensation” of the Summary

Compensation Table. Upon receipt of a work visa granting Mr. Ligner authorization to work in the United States and his

execution of a U.S. employment agreement, his eligibility to participate in the UK Savings Plan will cease.

Supplemental savings retirement plan. Mr. Stubblefield was eligible to participate in the Avantor Supplemental Savings

and Retirement Plan (the “SSRP”). The SSRP is a nonqualified deferred compensation plan that became effective on

November 14, 2013, and was closed to additional contributions in September 2014. Under the SSRP, eligible participants

were entitled to defer up to 50% of their base salaries and up to 100% of their annual cash bonus awards. In addition, the

SSRP allowed the Company to credit certain matching amounts to the notional account of each eligible participant for

each year. These matching amounts were provided to restore matching amounts to which the participant would otherwise

be entitled under the applicable Savings Plan, but which are limited due to earnings limitations under federal income tax

rules. For more information regarding this plan, see “Executive Compensation — Executive Compensation Tables —

Supplemental Savings Retirement Plan.”

Perquisites and Other Personal Benefits

Our Compensation and Human Resources Committee periodically reviews the levels of perquisites and other personal

benefits provided to our named executive officers. The perquisites and other benefits provided to our named executive

officers in 2025 included a financial planning allowance and the cost of providing an annual physical, and for Mr. Ligner,

relocation expenses and a car allowance (pursuant to the terms of the Ligner Agreement). In addition, our named

executive officers are offered health coverage and disability insurance under the same programs as all Avantor

associates.

Other Compensation Policies and Practices

Stock Ownership Guidelines

We maintain stock ownership guidelines that are intended to align the economic interests of our executive officers with

those of our stockholders. For purposes of the guidelines, the value of an executive’s stock ownership includes all shares

of the Company’s common stock owned by the executive outright; shares owned jointly with or separately by the

individual’s spouse and/or children; shares held in trusts, brokerage accounts, deferred accounts, employee benefit or

savings plans or any other personal account for which beneficial ownership would be attributed; and unvested restricted

stock and restricted stock units. Shares are not counted as owned for purposes of our share ownership guidelines if they

are underlying any unvested performance shares or other performance-based awards or underlying any stock option

award or SAR award, whether or not vested.

Our stock ownership guidelines set the following target levels:

Title Stock Ownership Multiple
Chief Executive Officer 6 times base salary
Chief Financial Officer and Segment Leaders 3 times base salary
Other Executive Officers 2 times base salary

Each of our executive officers must attain the minimum stock ownership level within five years of becoming subject to the

guidelines. Until the minimum stock ownership threshold is met, an executive officer is generally prohibited from selling

shares of Company stock, with the exception of sales to pay the exercise price of stock options or to cover taxes at the

time of vesting. As of December 31, 2025, each of Messrs Jones, Walker, Goudier and Sokenu have met their ownership

requirements and Mr. Ligner is on track to meet the requirement within five years.

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Executive Compensation

Clawback Policies

The Compensation and Human Resources Committee has adopted a clawback policy to comply with the requirements of

Section 954 of the Dodd-Frank Act and the related rules and regulations promulgated by the SEC and NYSE (the

“restatement recovery policy”). The restatement recovery policy provides for the mandatory recovery of incentive-based

compensation received by current and former executive officers in the event of a material financial restatement.

In addition to the restatement recovery policy, the Compensation and Human Resources Committee has adopted a robust

incentive compensation recoupment policy (the “incremental clawback policy”) that applies to all cash and performance-

based and time-based equity awards made to any Avantor associates, including our executive officers. This policy

provides for forfeiture or recoupment of certain cash and equity compensation, including time-based equity awards, in the

event of a restatement of our financial statements or other detrimental conduct. Specifically, forfeiture or recoupment is

authorized if:

A covered participant engages in misconduct that results in a restatement of our financial statements, due to a material

error, during the covered participant’s employment or within three years thereafter; or

A covered participant engages in any other detrimental activity, including (i) unauthorized disclosure of any confidential

or proprietary information; (ii) any activity that would be grounds to terminate the participant’s employment or service for

cause; (iii) a breach by the participant of any restrictive covenant by which such participant is bound, including, without

limitation, any covenant not to compete or not to solicit; or (iv) fraud or conduct contributing to any financial

irregularities, as determined by the Compensation and Human Resources Committee in its sole discretion.

This incremental clawback policy gives the Compensation and Human Resources Committee discretion to determine the

method of recovering compensation and the amount to be recovered.

Insider Trading Policy

We have adopted an insider trading policy governing the purchase, sale, and/or other disposition of our securities by our

directors, officers, and employees. We believe this policy is reasonably designed to promote compliance with insider

trading laws, rules and regulations and exchange listing standards applicable to the Company. The policy prohibits our

directors, officers, employees, and certain other covered persons from illegally trading in Company securities while aware

of material non-public information about the Company or its securities. Additionally, certain individuals are prohibited from

trading securities during various times throughout the year, and certain individuals must receive pre-clearance from our

Insider Trading Compliance Officer prior to trading. For more information regarding our insider trading policy, see Exhibit

19 to our Annual Report on Form 10-K for the year ended December 31, 2025.

Hedging, Short Sales and Pledging Policies

Our Insider Trading Policy, which applies to all directors, officers and employees, prohibits pledging any Avantor shares

absent pre-clearance approval. In addition, the policy prohibits covered employees from engaging in hedging or

monetization transactions involving Company securities, such as prepaid variable forwards and collars, or short sales of

our securities, and from holding Company securities in a margin account or pledging Company securities as collateral for

a loan absent pre-clearance approval.

2019 Employee Stock Purchase Plan

We sponsor the Avantor, Inc. 2019 Employee Stock Purchase Plan (the “Avantor ESPP”). The Avantor ESPP is designed

to encourage employees to become stockholders and to increase their ownership of our common stock. The overarching

Avantor ESPP plan maintains a limit of 2,000,000 shares, along with an annual contribution cap of $25,000 and an

individual limit of 3,000 shares per offering period. Shares of our common stock issued under the Avantor ESPP will be

issued at the lower of the share price on the first or last day of the offering period plus a discount to market of 15%. Each

offering period is equal to six months. The Avantor ESPP is also intended to comply with the requirements of Section 423

of the Code and to assure the participants of the tax advantages provided thereby.

64 2026 Proxy Statement

Executive Compensation

Accounting and Tax Considerations

In making decisions about compensation arrangements, we continue to consider the impact of regulatory provisions,

including the provisions of Section 409A of the Internal Revenue Code (the “Code”), as amended, regarding non-

qualified deferred compensation, the “golden parachute” provisions of Section 280G of the Code, as amended, and the

provisions of Section 162(m) of the Code, as well as how various elements of compensation will impact our financial

results. While the Compensation and Human Resources Committee considers regulatory provisions and the impact of

compensation elements on our financial results as factors in determining compensation arrangements, the Compensation

and Human Resources Committee believes that it is in the best interests of our stockholders to maintain flexibility in our

approach to compensation arrangements and to structure a program that we consider to be the most effective at

attracting, motivating and retaining key executives.

Policies and Procedures on the Timing of Equity Awards in Relation to the

Disclosure of Material Nonpublic Information

Our long-standing practice has been to grant long-term incentive equity awards on a predetermined schedule. At the first

quarterly meeting of any new fiscal year, the Compensation and Human Resources Committee or, with respect to the

CEO’s equity award, the Board, reviews and approves the value and amount of the equity compensation to be awarded

(inclusive of restricted stock units, performance stock units, and stock options) to executive officers with the grant of

approved equity awards occurring on the day of approval. The first quarterly meeting of the Board typically occurs after

the Company’s release of the financial results for the prior year through the filing of the Company's Annual Report on

Form 10-K, as well as a Current Report on Form 8-K and accompanying earnings release and earnings call for the

relevant fiscal year.

The Compensation and Human Resources Committee did not take material nonpublic information into account when

determining the timing and terms of long-term incentive equity awards in 2025 and does not time the disclosure of material

nonpublic information for the purpose of affecting the value of executive compensation. Instead, the timing of grants is in

accordance with the yearly compensation cycle, with awards granted at the start of the new fiscal year to incentivize the

executives to deliver on the Company’s strategic objectives for the new fiscal year.

65

Executive Compensation

Compensation and Human Resources

Committee Report

Our Compensation and Human Resources Committee has reviewed and discussed the foregoing Compensation

Discussion and Analysis with management. Based on that review and discussion, the Compensation and Human

Resources Committee recommended to the Board of Directors that the Compensation Discussion and Analysis be

included in this Proxy Statement and by reference in Avantor’s Annual Report on Form 10-K for the year ended December

31, 2025.

Respectfully submitted by the Compensation and Human Resources Committee of the Board of Directors.

Michael Severino , Chair

Lan Kang

Gregory Lucier

Sanjeev Mehra

Gregory Summe

The foregoing Report of the Compensation and Human Resources Committee does not constitute soliciting material and

should not be deemed filed or incorporated by reference into any other filing of the Company under the Securities Act of

1933, as amended, or the Securities and Exchange Act of 1934, as amended, except to the extent that the Company

specifically incorporates the report by reference therein.

66 2026 Proxy Statement

Executive Compensation Tables

Summary Compensation Table

The table below summarizes the total compensation paid to or earned by each of our named executive officers for the

years indicated.

Name and Principal Position Year Salary ($) (1) Bonus ($) Stock Awards ($) (2) Option Awards ($) (2) Non-Equity Incentive Plan Compensation ($) (3) Change in Pension Value and Nonqualified Deferred Compensation Earnings ($) (4) All Other Compensation ($) (5) Total ($)
Emmanuel Ligner Director, President and Chief Executive Officer 2025 379,297 2,499,990 2,499,998 330,038 186,301 5,895,624
R. Brent Jones Executive Vice President and Chief Financial Officer 2025 653,269 4,823,755 749,999 272,288 39,355 6,538,667
2024 611,519 2,059,777 625,020 554,220 35,915 3,886,451
2023 221,154 200,000 2,817,998 2,561,102 18,526 22,015 5,840,795
Corey Walker President Laboratory Solutions 2025 700,000 4,173,757 749,999 322,755 41,305 5,987,816
Benoit Gourdier Executive Vice President Bioscience Production 2025 550,000 3,804,417 624,999 215,921 30,082 5,225,419
2024 516,057 2,059,777 625,020 512,210 20,000 3,733,064
Claudius Sokenu Executive Vice President, Chief Legal and Compliance Officer 2025 550,000 2,576,284 375,000 208,317 40,312 3,749,913
2024 543,654 1,400,628 425,033 431,739 31,804 2,832,857
Michael Stubblefield Former Chief Executive Officer 2025 1,140,000 8,125,784 2,749,997 1,022,795 39,355 13,077,931
2024 1,126,846 8,651,135 2,625,038 2,085,069 37,550 14,525,638
2023 1,140,000 $ — 8,529,219 2,437,053 188,100 7,895 36,500 12,338,767

(1) Amounts reflect each named executive officer’s base salary earned for 2025, 2024 and 2023, as applicable. For Mr. Ligner, who is

based in the United Kingdom, the amount reflects his salary earned in 2025, and has been converted from British Pounds Sterling to

U.S dollars using the average of the monthly average exchange rates for 2025 (1.31873).

(2) The amounts reflected in these columns represent the aggregate grant date fair value of awards granted to the named executive

officer by us in the applicable year computed in accordance with Topic 718, disregarding the effect of estimated forfeitures. The

assumptions made in the valuation of our equity awards are found in Note 18 to our audited financial statements included in our

annual report on Form 10-K for the year ended December 31, 2025. For awards that are subject to performance conditions and are

included in the table above as stock awards, we report the grant date fair value based upon the probable outcome of such conditions

consistent with our estimate of aggregate compensation cost to be recognized over the service period determined under Topic 718,

disregarding the effect of estimated forfeitures. The grant date fair value of the PSUs, assuming the maximum level of achievement

are: Mr. Jones—$2,932,238, Mr. Walker—$2,932,238, Mr. Gourdier—$2,443,559, Mr. Sokenu—$1,466,136, and Mr. Stubblefield

—$10,751,593. The amounts reflected in this column do not represent the actual amounts paid to or realized by the named executive

officers for these awards.

(3) Amounts reflect performance-based cash incentive awards under the ICP or predecessor plans for each of 2025, 2024 and 2023, as

applicable. For more information on the terms of the cash incentive plan, see “Executive Compensation — Elements of

Compensation — What We Pay and Why — Performance-Based Cash Incentive Compensation.” The ICP award for Mr. Ligner has

been converted from British Pounds Sterling to U.S. dollars based on the exchange rate as of the close of business on December 31,

2025 (1.3444).

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Executive Compensation Tables

(4) For Mr. Stubblefield, the amounts reflect the year-over-year change in his U.S. Pension Plan benefits. In connection with the

termination of the U.S. Pension Plan in 2024, Mr. Stubblefield elected to receive a lump-sum distribution via direct rollover in

December 2024, totaling $34,101.

(5) All other compensation for 2025 includes:

Company Contributions to pension (a)($) Company savings plan employer contributions (b)($) Relocation expenses ($) Miscellaneous (c)($) Total ($)
Emmanuel Ligner 8,517 153,357 24,427 186,301
R. Brent Jones 19,355 20,000 39,355
Corey Walker 19,355 21,950 41,305
Benoit Gourdier 5,355 24,727 30,082
Claudius Sokenu 19,355 20,957 40,312
Michael Stubblefield 19,355 20,000 39,355

(a) The amount represent our contribution to the UK Savings Plan on behalf of Mr. Ligner and has been converted from British

Pounds Sterling to U.S. dollars using the average of the monthly average exchange rates for 2025 (1.31873).

(b) Amounts represent our matching and nonelective contributions to the Savings Plan on behalf of such executive with respect to

fiscal year 2025.

(c) For Messrs. Walker, Gourdier and Sokenu, amounts represent the cost of providing financial planning services and the cost of

providing an annual physical examination. For Messrs. Jones and Stubblefield, amounts represent the cost of providing financial

planning services. For Mr. Ligner, amounts represent the cost of providing financial planning services and a car allowance, each

of which has been converted from British Pounds Sterling to U.S. dollars using the average of the monthly average exchange

rates for 2025 (1.31873).

(6) Mr. Stubblefield was our Chief Executive Officer until August 17, 2025. After August 18, 2025, Mr. Stubblefield remained an employee

of the Company until February 28, 2026.

68 2026 Proxy Statement

Executive Compensation Tables

Grants of Plan-Based Awards

The following table provides information about equity and non-equity awards issued to our named executive officers in

2025.

Name Award Type Estimated possible payments under Non-equity incentive plan awards (1) Estimated possible payments under equity incentive plan awards (2) All other Stock awards: number of shares of Stock or units (#) (3) All other option awards: number of securities underlying options (#) Exercise or base price of option awards ($) (4) Grant date fair value of stock and option awards (S) (5)
Grant Date Threshold ($) Target ($) Maximum ($) Threshold (#) Target (#) Maximum (#)
Emmanuel Ligner (6) ICP 766,512 1,533,024 3,066,047
PPNQ 8/18/2025 573,394 14.04 2,499,998
RSUs 8/18/2025 195,924 2,499,990
R. Brent Jones ICP 264,000 528,000 1,056,000
PSUs 2/20/2025 42,882 85,763 171,526 1,466,119
NQ 2/20/2025 103,878 17.49 749,999
RSUs 2/20/2025 80,045 1,399,987
RSUs 5/9/2025 162,866 1,957,649
Corey Walker ICP 280,000 560,000 1,120,000
PSUs 2/20/2025 42,882 85,763 171,526 1,466,119
NQ 2/20/2025 103,878 17.49 749,999
RSUs 2/20/2025 42,881 749,989
RSUs 5/9/2025 162,866 1,957,649
Benoit Gourdier ICP 220,000 440,000 880,000
PSUs 2/20/2025 35,735 71,470 142,940 1,221,780
NQ 2/20/2025 86,565 17.49 624,999
RSUs 2/20/2025 35,734 624,988
RSUs 5/9/2025 162,866 1,957,649
Claudius Sokenu ICP 206,250 412,500 825,000
PSUs 2/20/2025 21,441 42,882 85,764 733,068
NQ 2/20/2025 51,939 17.49 375,000
RSUs 2/20/2025 21,440 374,986
RSUs 5/9/2025 122,149 1,468,231
Michael Stubblefield ICP 1,140,000 1,881,000 3,762,000
PSUs 2/20/2025 157,233 314,466 628,932 5,375,796
NQ 2/20/2025 380,886 17.49 2,749,997
RSUs 2/20/2025 157,232 2,749,988

(1) These columns reflect the potential payments under the ICP for 2025 performance including maximum achievement of the corporate

targets and individual performance objectives, to the extent applicable. For more information regarding the 2025 ICP, including the

corporate target and individual strategic goal component see “Executive Compensation — Elements of Compensation — What We

Pay and Why — Performance-Based Cash Incentive Compensation.”

(2) These share amounts represent the possible performance stock unit award payouts at various levels of attainment for the

performance period beginning January 1, 2025 and ending December 31, 2027 issued pursuant to the 2019 Equity Incentive Plan.

(3) Represents restricted stock units issued pursuant to the 2019 Equity Incentive Plan.

(4) For Mr. Ligner, represents premium-priced non-qualified stock options (“PPNQ”) issued with an exercise price equal to 110% of the

closing price of Avantor stock ($12.76) on the August 18, 2025 grant date.

(5) Amounts reflect the aggregate grant date fair value of premium priced non-qualified stock options, non-qualified stock options,

restricted stock units and performance stock units granted to our named executive officers in 2025 in accordance with Topic 718. For

the assumptions used in determining the grant date fair value under Topic 718, see footnote 2 to the Summary Compensation Table.

These amounts do not correspond to the actual value that will be received by the named executive officer.

(6) The threshold, target and maximum amounts for Mr. Ligner are calculated based on the conversion of his 2025 base salary to U.S.

dollars using the exchange rates described in footnote (1) to the Summary Compensation Table.

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Executive Compensation Tables

Narrative Disclosure to Summary Compensation Table and Grants of Plan-

Based Awards in 2025

Employment Arrangements

We have entered into written agreements with each of our named executive officers governing the terms of their

respective employment with us.

Mr. Ligner’s Employment Agreement

Our UK subsidiary, VWR International Ltd., entered into the Ligner Agreement, effective as of July 15, 2025, pursuant to

which Mr. Ligner serves as our President and Chief Executive Officer. The Ligner Agreement continues until terminated by

either party providing at least 90 days’ written notice (other than in the event of a termination of Mr. Ligner by the

Company for “cause” (as defined in the Ligner Agreement)). Upon receipt of a work visa granting Mr. Ligner authorization

to work in the United States, the Ligner Agreement will also terminate, and he will be employed by the Company on

substantially consistent terms.

The Ligner Agreement provides for a base salary subject to review and adjustment no less frequently than annually by our

Board, as well as the opportunity to earn an annual bonus in a threshold amount of 75% of base salary, a target amount

equal to 150% of base salary and a maximum amount equal to 300% of base salary in accordance with the terms of the

Ligner Agreement and the financial metrics under the Company’s annual bonus plan. For more information, see “Elements

of Compensation — What We Pay and Why — Performance-Based Cash Incentive Compensation.”

In addition, the Ligner Agreement provides Mr. Ligner with standard benefits normally provided to other senior executives,

including payment for or reimbursement of commercially reasonable out-of-pocket business expenses; five weeks of paid

vacation; and certain payments and benefits in the event that Mr. Ligner’s employment is terminated under specified

circumstances, subject to compliance with certain restrictive covenants. For more information, see “Executive

Compensation — Executive Compensation Tables —Termination and Change in Control Arrangements.”

Employment Agreements with Messrs. Jones, Walker, Gourdier and Sokenu

We entered into employment agreements with Mr. Jones effective as of July 12, 2023 , Mr. Walker effective as of June 19,

2024 , Mr. Gourdier effective as of July 19, 2023 and Mr. Sokenu, effective as of May 19, 2023, (each an “EVP

Employment Agreement” and collectively, the “EVP Employment Agreements”) pursuant to which each serves or served,

as applicable, in the positions and with a base salary as described above. Messrs. Jones, Walker and Gourdier's EVP

Employment Agreements provide for the opportunity to earn an annual bonus with a target amount equal to 80% of base

salary. Mr. Sokenu's EVP Employment Agreement provides for the opportunity to earn an annual bonus with a target

amount equal to 75% of base salary. Each EVP Employment Agreement provides the applicable named executive officer

with the opportunity to earn an annual bonus in accordance with the terms of the 2025 ICP. For more information, see

“Executive Compensation — Elements of Compensation — What We Pay and Why — Performance-Based Cash

Incentive Compensation.”

Pursuant to their respective EVP Employment Agreements, each applicable named executive officer is also provided with

all standard benefits that we normally provide to other similarly-situated executives. Each named executive officer is

provided with four weeks of, paid vacation per year. Each EVP Employment Agreement also provides for certain payments

and benefits in the event that the applicable named executive officer’s employment is terminated under specified

circumstances. For more information, see “Executive Compensation — Executive Compensation Tables — Termination

and Change in Control Arrangements.”

70 2026 Proxy Statement

Executive Compensation Tables

Mr. Stubblefield’s Transition Agreement

In April 2025, we determined to end the employment of Mr. Stubblefield and entered into the Transition Agreement which

provided for a transition period wherein Mr. Stubblefield would remain employed as the Director, President and Chief

Executive Officer until a successor was appointed and following such appointment, Mr. Stubblefield would remain a non-

executive employee advisor until February 28, 2026, to facilitate a smooth transition. As part of the Transition Agreement,

upon the termination of his employment on February 28, 2026, Mr. Stubblefield was eligible to receive the contractual

involuntary separation payments and benefits under his existing employment agreement, subject to his execution and

non-revocation of a release of claims. For purposes of his 2025 annual bonus, Mr. Stubblefield’s individual performance

metrics were deemed achieved based on the Company’s financial performance levels. No equity awards were

accelerated in connection with the transition or subject to continued vesting following the transition, and Mr. Stubblefield

remains subject to the restrictive covenants in his employment agreement.

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Outstanding Equity Awards at 2025 Fiscal Year-End

The following table provides information as of December 31, 2025, regarding the outstanding equity awards of our named

executive officers under the 2019 Equity Incentive Plan, the Vail Holdco Corp Equity Incentive Plan (the “Vail Plan”) and

Legacy Avantor Equity Plan. For more information, see “Executive Compensation — Elements of Compensation — Long

Term Incentive Programs.”

Name Grant Date Option awards — Number of securities underlying unexercised options (#) exercisable Number of securities underlying unexercised options (#) unexercisable (1) Option exercise price ($) Option Date Expiration Stock awards — Number of shares or units of stock that have not vested (#) (2) Market value of shares or units of stock that have not vested ($) (3) Equity incentive plan awards: Number of unearned shares, units or other rights that have not vested (#) (4) Equity incentive plan awards: Market or payout value of unearned shares, units or other rights that have not vested (#) (3)
Emmanuel Ligner 08/18/25 573,394 14.04 18/08/2035 195,924 2,245,289
R. Brent Jones 08/07/23 147,779 147,780 20.76 08/07/33 61,717 707,277
02/23/24 20,918 41,835 24.35 02/23/34 17,111 196,092 25,667 294,144
02/20/25 103,878 17.49 02/20/35 80,045 917,316 42,882 491,422
05/09/25 162,866 1,866,444
Corey Walker 06/21/24 23,488 46,974 22.12 06/21/34 18,836 215,861 28,255 323,797
02/20/25 103,878 17.49 02/20/35 42,881 491,416 42,882 491,422
05/09/25 162,866 1,866,444
Benoit Gourdier 10/02/23 19,640 19,641 20.85 10/02/33 8,393 96,184
02/23/24 20,918 41,835 24.35 02/23/34 17,111 196,092 25,667 294,144
02/20/25 86,565 17.49 02/20/35 35,734 409,512 35,735 409,523
05/09/25 162,866 1,866,444
Claudius Sokenu (5) 07/24/23 16,464 16,465 22.84 07/24/33 6,841 78,398 13,682 156,796
02/23/24 14,225 28,449 24.35 02/23/34 11,635 133,337 17,454 200,017
02/20/25 51,939 17.49 02/20/35 21,440 245,702 21,441 245,714
05/09/25 122,149 1,399,828
Michael Stubblefield 09/30/16 750,000 13.11 09/30/26
12/13/17 3,380,200 23.21 12/13/27
02/20/20 456,204 17.67 02/20/30
02/25/21 234,192 27.64 02/25/31
02/23/22 151,607 50,536 33.09 02/23/32 17,472 200,229
02/24/23 119,957 119,958 24.62 02/24/33 49,502 567,293 99,005 1,134,592
02/23/24 87,853 175,705 24.35 02/23/34 71,868 823,607 107,803 1,235,417
02/20/25 380,886 17.49 02/20/35 157,232 1,801,879 157,233 1,801,890

(1) The stock options granted from February 2021 through October 2023 vest at a rate of 25% per year on each anniversary of the date

of grant and the stock options granted from February 23, 2024, through August 18, 2025, vest at a rate of one-third per year on each

anniversary of the date of grant, i n each case, subject to the named executive officer’s continued employment through such date.

(2) Restricted stock units granted from February 2021 through October 2023 vest at a rate of 25% per year on each anniversary of the

date of grant and the restricted stock units granted on February 23, 2024, February 20, 2025 and August 20, 2025 vest at a rate of

one-third per year on each anniversary of the date of grant, the restricted stock units granted on May 9, 2025 vest at a rate of 100%

on second anniversary of the date of grant, in each case, subject to the named executive officer’s continued employment through

such date.

(3) Market value is calculated based on the closing price of Avantor’s common stock on December 31, 2025 as reported on the NYSE

($11.46 per share).

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(4) Represents the number of performance stock units at next higher level attainment. performance stock units cliff-vest, if at all, subject

to attainment of the applicable performance metrics at the end of the three-year performance period.

(5) On July 24, 2023, Mr. Sokenu received (i) 10,945 restricted stock units that vest at a rate of 50% per year on each anniversary of the

date of grant and (ii) 13,682 restricted stock units and 32,929 stock options that vest at a rate of 25% per year on each anniversary of

the date of grant. In the event of his termination without cause, the remaining unvested portion of Mr. Sokenu's July 24, 2023 awards

will vest in full.

Options Exercised and Stock Vested

The following table sets forth the value realized upon exercise of stock options and vesting of restricted stock units during

fiscal year 2025 by each of the named executive officers.

Name Option awards — Number of shares acquired on exercise (#) Value realized on exercise ($) (1) Stock awards — Number of shares acquired on vesting Value realized on vesting ($) (2)
Emmanuel Ligner
R. Brent Jones 8,556 148,019
Corey Walker 9,418 127,802
Benoit Gourdier 12,753 205,811
Claudius Sokenu 14,712 225,256
Michael Stubblefield 96,246 1,673,967

(1) Value realized on exercise is based on the fair market value of Avantor’s common stock on the date of exercise minus the exercise

price and does not necessarily reflect cash actually received by the named executive officer.

(2) Value realized on vesting is based on the fair market value of Avantor’s common stock on the date of vesting before tax withholding

and does not necessarily reflect cash actually received by the named executive officer.

Pension Benefits

Supplemental Savings Retirement Plan

Mr. Stubblefield was eligible to participate in the SSRP. The SSRP was a nonqualified deferred compensation plan that

became effective November 14, 2013 and was closed to additional contribution in September 2014. Under the SSRP,

eligible participants were entitled to defer up to 50% of their base salaries and up to 100% of their annual bonus awards.

Earnings and losses on each notional account are credited based on the performance of the benchmark funds available

under the SSRP that the participant selects. Any deferred amounts and earnings and losses thereon will be credited to a

notional account for the applicable participant and become a liability for us to such participant.

The table below provides information with respect to Mr. Stubblefield’s SSRP notional accounts.

Name Executive contributions in last FY ($) Registrant contributions in last FY ($) Aggregate earnings (losses) in last FY ($) Aggregate (withdrawals) distributions ($) Aggregate balance at last FYE ($)
Michael Stubblefield 716 4,209

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Termination and change in control arrangements

Ligner Agreement

Involuntary termination without cause (other than due to death or disability) or voluntary termination for good reason. In

the event Mr. Ligner’s employment is terminated by us without “cause” or he resigns for “good reason” (as such terms are

defined in the Ligner Agreement), in each case, subject to continued compliance with the restrictive covenants described

below and the execution and non-revocation of a release of claims against us, we will provide him with:

an amount equal to two times (or three times if such termination occurs within a two-year period following a “change in

control” as defined in the Company’s 2019 Equity Incentive Plan) the sum of (i) basic pay as of the Termination Date

and (ii) target annual bonus, in addition to any payment in lieu of notice and statutory payments, as applicable (the

“Severance Payment”). Payments will begin as soon as practicable following the termination date, not to exceed 60

days following the termination date. Any Severance Payments that are delayed as a result of the execution of the

separation and release agreement will be paid as part of the first installment of the Severance Payment;

a pro-rata portion of the annual bonus for the fiscal year in which the Termination Date occurs based on achievement of

target performance for such year determined by multiplying the amount of the target annual bonus for the full fiscal year

by a fraction, the numerator of which is the number of days during the fiscal year in which the Termination Date occurs

that Mr. Ligner had been employed, and the denominator of which is 365; and

a lump-sum cash payment in an amount equal to $75,000 if a Qualifying Termination occurs following Mr. Ligner’s

relocation to the United States.

Restrictive covenants. As a result of the restrictive covenants contained in the Ligner Agreement, Mr. Ligner agreed not to

disclose our confidential information at any time, and for the period during which he is employed by us and for the one-

year period thereafter, he has also agreed not to solicit our employees or customers, compete with us, or interfere with our

business. In addition, Mr. Ligner has agreed not to disparage us at any time, and we have agreed to instruct our officers

and directors not to publicly disparage Mr. Ligner.

Executive Severance and Change in Control Plan

In 2025, the Company established the Severance Plan applicable to its U.S.-based executive officers, transitioning from

employment agreement based severance provisions.

Involuntary Termination without “Cause” Not Following a Change in Control. In the event that any of Messrs. Jones,

Walker, Gourdier and Sokenu is terminated by us without “cause,” other than within a two-year period following a “change

in control” (as such terms are defined in the Severance Plan), subject to continued compliance with the restrictive

covenants described below and the execution and non-revocation of a release of claims against us, we will provide him

with:

an amount equal to one times his then-current base salary, paid in equal installments in accordance with our standard

payroll policies, for a period of 12 months;

an amount equal to one times his then-current target bonus opportunity, paid in equal installments in accordance with

our standard payroll policies, for a period of 12 months; and

an amount equal to one times his then-current target bonus opportunity, prorated for the year of such termination, paid

at target in equal installments in accordance with our standard payroll policies, for a period of 12 months;

continued medical insurance benefits that the applicable named executive officer would otherwise be eligible to receive

as an active employee for 12 months following the termination date, or, if earlier, until the date upon which the

applicable named executive officer becomes eligible to receive medical benefits from a subsequent employer; and

if such termination occurs prior to May 6, 2027, all unvested equity will continue to vest for 12 months post-termination.

Involuntary termination without cause or voluntary termination for good reason following a change in control. In the event

that any of Messrs. Jones, Walker, Gourdier and Sokenu are terminated by us without “cause” or resigns for “good

reason,” in each case within a two-year period following a “change in control” (as such terms are defined in the Severance

Plan) and subject to continued compliance with the restrictive covenants described below and the execution and non-

revocation of a release of claims against us, we will provide him with:

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an amount equal to two times his then-current base salary, paid in equal installments in accordance with our standard

payroll policies, for a period of 12 months;

an amount equal to two times his then-current target bonus opportunity, paid in equal installments in accordance with

our standard payroll policies, for a period of 12 months; and

an amount equal to one times his then-current target bonus opportunity, prorated for the year of such termination, paid

at target in equal installments in accordance with our standard payroll policies, for a period of 12 months; and

continued medical insurance benefits that the applicable named executive officer would otherwise be eligible to receive

as an active employee for 18 months (following the termination date, or, if earlier, until the date upon which the

applicable named executive officer becomes eligible to receive medical benefits from a subsequent employer.

Restrictive covenants. As a result of the restrictive covenants contained in the Severance Plan, each of Messrs. Jones,

Walker, Gourdier and Sokenu agreed not to disclose our confidential information at any time. Each has also agreed for the

period they are employed by us and for the one-year (two years with respect to the solicitation of our employees or

customers) period thereafter, not to compete with us or solicit our employees or customers. Messrs. Jones, Walker,

Gourdier and Sokenu have also agreed not to disparage us at any time.

Section 280G “Golden Parachute” Treatment. The Severance Plan provides that if any payments or benefits to which the

participant becomes entitled would be considered “excess parachute payments” under Section 280G of the Code, then

the amount of such payments will be reduced to avoid such characterization and the resulting excise taxes if such

reduction in payments will put the participant in a better net after tax position.

Stubblefield Agreement

Involuntary termination without cause (other than due to death or disability) or voluntary termination for good reason. In

the event Mr. Stubblefield’s employment had been terminated by us without “cause” or he resigns for “good reason” (as

such terms are defined in the Stubblefield Agreement), in each case, subject to continued compliance with the restrictive

covenants described below and the execution and non-revocation of a release of claims against us, we were to provide

him with:

an amount equal to two times his then-current base salary (or three times if such termination had occurred within a two-

year period following a “change in control” (as defined in the Company’s 2019 Equity Incentive Plan), paid in equal

installments in accordance with our standard payroll policies, for a period of 24 months (or 36 months if such

termination occurs within a two-year period following a “change in control”), beginning on the first payroll date following

the 45th day after the termination date;

an amount equal to his then-current target bonus opportunity (or three times if such termination had occurred within a

two-year period following a “change in control”), paid in equal installments in accordance with our standard payroll

policies, for a period of 12 months (or 36 months if such termination had occurred within a two year period following a

“change in control”), beginning on the first payroll date following the 45th day after the termination date; and

continued medical insurance benefits that Mr. Stubblefield would have otherwise been eligible to receive as an active

employee for 24 months (or 36 months if such termination had occurred within a two year period following a “change in

control”) following the termination date, or, if earlier, until the date upon which Mr. Stubblefield had become eligible to

receive medical benefits from a subsequent employer.

Restrictive covenants. As a result of the restrictive covenants contained in the Stubblefield Agreement, Mr. Stubblefield

agreed not to disclose our confidential information at any time, and for the period during which he is employed by us and

for the one-year period thereafter, he has also agreed not to solicit our employees or customers, compete with us, or

interfere with our business. In addition, Mr. Stubblefield has agreed not to disparage us at any time, and we have agreed

to instruct our officers and directors not to publicly disparage Mr. Stubblefield.

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Section 280G “Golden Parachute” Treatment. The Stubblefield Agreement provided that if any payments or benefits to

which he becomes entitled would be considered “excess parachute payments” under Section 280G of the Code, then the

amount of such payments will be reduced to avoid such characterization and the resulting excise taxes if such reduction in

payments will put Mr. Stubblefield in a better net after tax position.

Potential Payments upon Termination or Change in Control

The following table describes the potential payments and benefits that would have been payable to our named executive

officers assuming an eligible termination (as described above under “Executive Compensation — Executive

Compensation Tables — Termination and Change in Control Arrangements”) of their employment on December 31, 2025,

the last business day of 2025, and a change in control also occurring on such date.

The amounts shown in the table below do not include:

payments and benefits to the extent they are provided generally to all salaried employees upon termination of

employment and do not discriminate in scope, terms or operation in favor of the named executive officers; or

distributions of previously vested plan balances under the Savings Plan and the SSRP (for more information about the

SSRP, see “Executive Compensation — Executive Compensation Tables — Supplemental Savings Retirement Plan”).

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Executive Compensation Tables

Name Involuntary termination without cause ($) (1) Termination due to death or disability ($) (2) Change in control (4)
Retirement (3) Without termination With involuntary termination without cause or resignation for good reason ($)
Emmanuel Ligner
Cash severance 5,110,079 4,088,063 7,665,118
Annual cash incentive 1,533,024 1,533,024
Equity awards (continued or accelerated vesting) (5) 2,245,289 2,245,289
Estimated health & welfare benefits
Total 6,643,102 6,333,352 11,443,431
R. Brent Jones
Cash severance 1,188,000 2,376,000
Annual cash incentive 528,000 528,000
Equity awards (continued or accelerated vesting) (5) 3,755,797 5,965,537 1,414,554 5,965,537
Estimated health & welfare benefits 6,443 9,664
Total 5,478,240 5,965,537 1,414,554 8,879,202
Corey Walker
Cash severance 1,260,000 2,520,000
Annual cash incentive 560,000 560,000
Equity awards (continued or accelerated vesting) (5) 2,138,184 4,204,158 4,204,158
Estimated health & welfare benefits 18,713 28,070
Total 3,976,897 4,204,158 7,312,228
Benoit Gourdier
Cash severance 990,000 1,980,000
Annual cash incentive 440,000 440,000
Equity awards (continued or accelerated vesting) (5) 2,149,082 3,975,566 96,184 3,975,566
Estimated health & welfare benefits 51,212 76,818
Total 3,630,294 3,975,566 96,184 6,472,384
Claudius Sokenu
Cash severance 962,500 1,925,000
Annual cash incentive 412,500 412,500
Equity awards (continued or accelerated vesting) (5) 1,940,384 3,062,318 391,989 3,062,318
Estimated health & welfare benefits 5,987 8,980
Total 3,321,371 3,062,318 391,989 5,408,798
Michael Stubblefield
Cash Severance 2,280,000 3,420,000
Annual Cash Incentive 1,881,000 5,643,000
Equity Awards (continued or accelerated vesting) (5) 11,736,805 3,036,705 11,736,805
Estimated health & welfare benefits 41,771 62,656
Total 4,202,771 11,736,805 3,036,705 20,862,461

(1) Upon termination without “cause” or for “good reason” (as such term is defined in the Ligner Agreement, the Severance Plan or the

Stubblefield Agreement, as applicable), (i) Mr. Ligner is generally entitled to the sum of (a) two times the sum of his then current base

salary and target bonus and (b) his target bonus for the year (prorated for the year of termination in which termination occurs, payable

in equal installments over the 12-month period following termination; and (ii) Messrs. Jones, Walker, Gourdier and Sokenu are

generally entitled to the sum of (a) one times the sum his then current base salary plus his target bonus and (b) his target bonus for

the year (prorated for the year of termination in which termination occurs, payable in equal installments over the 12-month period

following termination and (c) if such termination occurs prior to May 6, 2027, all unvested equity will continue to vest for 12 months

post-termination and (d) are entitled to continued health benefits for up to 12 months following termination, and (iii) Mr. Stubblefield

was generally entitled to (x) two times the sum of his then current base salary payable in equal installments over the 24-month period

following termination, (y) one times his target bonus for the year in which the termination occurs payable in equal installments over

the 12-month period following termination and (z) continued health benefits for up to 24 months following termination, and (iv) the

equity awards granted to Mr. Sokenu upon joining the Company on July 23, 2023 will vest in full upon a qualifying termination per the

terms of his employment agreement.

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(2) Upon termination by reason of death, the named executive officer’s beneficiary or estate, as applicable, will be entitled to receive

compensation and benefits accrued prior to the death plus (i) all unvested restricted stock units will vest, (ii) all unvested stock

options will vest and remain exercisable for one year from the date of death and (iii) all unvested performance stock units will vest at

the target level of achievement. Upon termination by reason of disability, the named executive officer will be entitled to receive

compensation and benefits accrued prior to the disability plus (x) all unvested restricted stock units will vest, (y) all unvested stock

options will vest and remain exercisable for one year from the date of disability and (z) all unvested performance stock units will vest

at the target level of achievement.

(3) Represents the value associated with the continued vesting of unvested equity that would apply under each grant’s retirement

provisions with respect to each named executive officer who met the eligibility requirements for retirement as of December 31, 2025.

Retirement is defined as termination of employment (other than for Cause) after reaching age 55, where the sum of age and years of

continuous employment equals at least 65. As of December 31, 2025, none of our named executive officers were retirement eligible.

(4) Upon an involuntary termination within two years of a change in control or a resignation for “good reason” (such good reason

termination within two years of a change in control) (as such term is defined in the Ligner Agreement, Severance Plan or the

Stubblefield Agreement, as applicable), (i) Mr. Ligner is generally entitled to the sum of (a) three times the sum of his then current

base salary and target bonus and (b) his target bonus for the year (prorated for the year of termination in which termination occurs,

payable in equal installments over the 12-month period following termination; and (ii) Messrs. Jones, Walker, Gourdier and Sokenu

are generally entitled to the sum of (a) two times the sum his then current base salary plus target bonus and (b) his target bonus for

the year (prorated for the year of termination in which termination occurs, payable in equal installments over the 12-month period

following termination and (c) are entitled to continued health benefits for up to 18 months following termination, and (iii) Mr.

Stubblefield was entitled to (a) three times the sum of his then current base salary plus target bonus for the year in which the

termination or resignation occurs payable in equal installments over the 36-month period following termination and (b) continued

health benefits for up to 36 months following termination. The Severance Plan and Stubblefield Agreement provide that if any

payments or benefits to which the participant becomes entitled would be considered “excess parachute payments” under Section

280G of the Code, then the amount of such payments will be reduced to avoid such characterization and the resulting excise taxes if

such reduction in payments will put the participant in a better net after tax position. The amount above reflects no reduction

of payments.

(5) Represents the value of all performance stock units, unvested stock options and restricted stock units issued by the Company that

would vest upon death, disability or a change in control and assumes a change in control price of $11.46, which was the closing price

of Avantor’s common stock as reported on the NYSE on December 31, 2025. “Double-trigger” change in control vesting provisions

were adopted in 2024 for all equity awards granted in 2024 and all future awards.

CEO Pay Ratio

In accordance with SEC rules, we are providing the ratio of the annual total compensation of our CEO to the median of the

annual total compensation of our employees (other than the CEO). Because the SEC rules for identifying the median

employee and calculating the pay ratio permit companies to use various methodologies and assumptions, to apply certain

exclusions, and to make reasonable estimates that reflect their employee populations and compensation practices, the

pay ratio reported by other companies may not be comparable with the pay ratio that we report.

For fiscal 2025:

Median Employee Total Annual Compensation: $ 47,791
CEO Total Annual Compensation: $ 7,090,019
Ratio of CEO Pay to Median Employee Compensation: 148:1

We believe the foregoing ratio is a reasonable estimate calculated in a manner consistent with the SEC rules.

Because we did not experience any material changes to our employee population or changes in employee compensation

arrangements during 2025, in accordance with SEC rules, we used the median employee identified and reported in 2024

using data as of December 31, 2024 for purposes of calculating the pay ratio disclosure with respect to 2025 and that

using this median employee will not significantly affect our pay ratio disclosure.

78 2026 Proxy Statement

Equity Compensation Plans

The following table provides information as of December 31, 2025 regarding the number of shares of our common stock

that may be issued under our equity compensation plans:

Plan Category Number of Securities to be issued upon Exercise of Outstanding Options, Warrants and rights (Millions)(#)(a)) Weighted Average Exercise Price of Outstanding Options, Warrants and Rights ($)(b) Number of Securities Remaining Available for Future Issuance Under Equity Compensation Plan (Excluding Securities Reflected in Column(a)) (Millions)(#)(c)
Equity Compensation Plans Approved by Security Holders 18.4 (1) 21.18 44.2 (2)
Equity Compensation Plans Not Approved by Security Holders
Total 18.4 21.94 44.2

(1) The number of securities to be issued upon exercise of outstanding options, warrants and rights includes 6.4 million options issuable

pursuant to outstanding equity awards under the Avantor, Inc. 2019 Equity Incentive Plan. The weighted-average exercise price of

such options is $22.34. It also includes 4.6 million shares issuable pursuant to outstanding equity awards under the Vail Holdco

Equity Incentive Plan. The weighted-average exercise price of such options is $23.21. It also includes 0.9 million shares issuable

pursuant to outstanding equity awards under the Avantor Funding, Inc. 2016 Equity Incentive Plan. The weighted-average exercise

price of such options is $12.42. Reflects the weighted average exercise price of stock options only. As restricted stock unit awards

have no exercise price, they are excluded from the weighted average exercise price calculation set forth in column (b).

(2) The number of securities remaining available for issuance includes 37.5 million shares that can be issued pursuant to future awards

under the 2019 Equity Incentive Plan as well as 0.9 million shares that can be issued pursuant to the Avantor, Inc. 2019 Employee

Stock Purchase Plan. The maximum number of shares that may be granted under the 2019 Equity Incentive Plan is 23,500,000

shares without giving effect to any “evergreen” increase, pursuant to which such “Absolute Share Limit” is automatically increased on

the first day of each fiscal year through 2029 in an amount equal to the lower of (x) 1% of the total number of shares outstanding on

the last day of the immediately preceding fiscal year and (y) a lower number of shares determined by the Board of Directors.

79

Pay Versus Performance Disclosure

In accordance with SEC rules, we prepared the analysis set forth below of the relationship between the compensation

actually paid to our principal executive officer (“PEO”) and non-PEO named executive officers (the “Non-PEO NEOs”), and

certain financial performance measures over the last five years.

Pay Versus Performance Disclosure Table

The following table sets forth the compensation for our PEO and the average compensation for our Non-PEO NEOs, both

as reported in the Summary Compensation Table and with certain adjustments to reflect the compensation actually paid

("CAP") to such individuals, as defined under SEC rules, for each of 2024, 2023, 2022, 2021 and 2020. The table also

provides information on our cumulative total stockholder return ("TSR"), the cumulative TSR of our peer group, Net

Income and Revenue over such years in accordance with SEC rules.

PAY VERSUS PERFORMANCE TABLE

Year (a) Summary Compensation Table Total for Emmanuel Ligner Compensation Actually Paid to Emmanuel Ligner Summary Compensation Table Total for Michael Stubblefield Compensation Actually Paid to Michael Stubblefield Average Summary Compensation Table Total for Non-PEO NEOs (1) (d) Average Compensation Actually Paid to Non-PEO NEOs (2) (e) Value of Initial fixed $100 Investment Based On: — Avantor Total Stockholder Return (3) (f) Peer Group Total Stockholder Return (g) Net Income (4) (millions) (h) Company Selected Measure (Revenue) (millions) (i)
2025 $ 5,895,624 $ 6,099,867 $ 13,077,931 $ ( 1,380,512 ) $ 5,375,454 $ 2,060,367 $ 40.71 $ 148.36 $ ( 530.2 ) $ 6,552.2
2024 $ — $ — $ 14,525,638 $ 11,178,551 $ 3,426,772 $ 1,778,724 $ 116.09 $ 146.87 $ 711.5 $ 6,783.6
2023 $ — $ — $ 12,338,767 $ 8,925,771 $ 3,683,836 $ 2,493,597 $ 125.79 $ 143.18 $ 321.1 $ 6,967.2
2022 $ — $ — $ 10,831,766 $ ( 28,632,167 ) $ 2,553,081 $ ( 7,183,678 ) $ 116.20 $ 140.29 $ 686.5 $ 7,512.4
2021 $ — $ — $ 13,260,913 $ 45,709,309 $ 3,538,486 $ 12,019,256 $ 232.18 $ 143.09 $ 572.6 $ 7,386.1

Notes:

(1) Compensation for our Current PEO, Emmanuel Ligner and Former PEO, Michael Stubblefield , reflects the amounts reported in the

“Summary Compensation Table” for the respective years. Average compensation for our non-PEO NEOs included: (a) for 2025, R.

Brent Jones, Corey Walker, Benoit Gourdier and Claudius Sokenu; (b) for 2024, R. Brent Jones, Benoit Gourdier, James Bramwell,

Randy Stone and Claudius Sokenu; (c) for 2023, R. Brent Jones, Randy Stone, James Bramwell, Frederic Vanderhaegen, Gerard

Brophy and Thomas Szlosek; and (d) for 2022 and 2021, Thomas Szlosek, Frederic Vanderhaegen, Gerard Brophy and Sheri Lewis.

(2) Compensation “actually paid” for the PEO and average compensation “actually paid” for our non-PEOs NEOs in each of 2025, 2024,

2023, 2022 and 2021 reflects the respective amounts set forth in columns (b) and (d) of the table above, adjusted as set forth in the

tables below, as determined in accordance with SEC rules. The dollar amounts reflected in columns (b) and (d) of the table above do

not reflect the actual amount of compensation earned by or paid to the PEO and our other Non-PEO NEOs during the applicable

year. For more information regarding the decisions made by our Compensation and Human Resources Committee in regard to the

PEO’s and our other Non-PEO NEOs’ compensation for fiscal year 2025, see “Compensation Discussion and Analysis —

Compensation Philosophy and Objectives — How We Make Compensation Decisions.”

80 2026 Proxy Statement

Pay Versus Performance Disclosure

PEO SUMMARY COMPENSATION TABLE TOTAL TO COMPENSATION ACTUALLY PAID RECONCILIATION:

Current PEO — 2025 Former PEO Michael Stubblefield — 2025 2024 2023 2022 2021
Total Compensation as reported in SCT $ 5,895,624 $ 13,077,931 $ 14,525,638 $ 12,338,767 $ 10,831,766 $ 13,260,913
Subtract change in the actuarial present value of pension benefits $ — $ — $ — $ ( 7,895 ) $ — $ ( 5,342 )
Add service cost of pension benefits $ — $ — $ — $ 2,684 $ 3,421 $ 3,388
Subtract grant date fair value of equity awards granted during covered year reported in SCT $ ( 4,999,988 ) $ ( 10,875,781 ) $ ( 11,276,173 ) $ ( 10,966,272 ) $ ( 9,684,956 ) $ ( 8,633,149 )
Add fair value of equity compensation granted in current year – value at year-end $ 5,204,231 $ 5,669,429 $ 9,149,167 $ 7,305,449 $ 3,260,458 $ 18,576,571
Add dividends accrued on unvested shares/share units $ — $ — $ — $ — $ — $ —
Add/subtract change in fair value from end of prior fiscal year to end of current fiscal year for awards made in prior fiscal years that were unvested at end of current fiscal year $ — $ ( 6,197,315 ) $ ( 1,323,388 ) $ ( 921,458 ) $ ( 28,816,798 ) $ 17,291,985
Add/subtract change in fair value from end of prior fiscal year to vesting date for awards made in prior fiscal years that vested during current fiscal year $ — $ ( 579,577 ) $ 463,117 $ 1,174,497 $ ( 4,226,057 ) $ 5,214,944
Subtract fair value of forfeited awards determined at end of prior year for awards made in prior fiscal years that were forfeited during current fiscal year $ — $ ( 2,475,199 ) $ ( 359,810 ) $ — $ — $ —
Compensation Actually Paid to PEO $ 6,099,867 $ ( 1,380,512 ) $ 11,178,551 $ 8,925,771 $ ( 28,632,167 ) $ 45,709,309

AVERAGE NON-PEO SUMMARY COMPENSATION TABLE TOTAL TO COMPENSATION ACTUALLY

PAID RECONCILIATION:

Non-PEO NEOs (Average) 2025 2024 2023 2022 2021
Total Compensation as reported in SCT $ 5,375,454 $ 3,426,772 $ 3,683,836 $ 2,553,081 $ 3,538,486
Subtract change in the actuarial present value of pension benefits $ — $ — $ ( 5,613 ) $ ( 1,726 ) $ ( 2,787 )
Add service cost of pension benefits $ — $ — $ 1,806 $ 2,495 $ 2,491
Subtract grant date fair value of equity awards granted during fiscal year reported in SCT $ ( 4,469,553 ) $ ( 2,405,576 ) $ ( 3,117,887 ) $ ( 1,963,157 ) $ ( 1,861,530 )
Add fair value of equity compensation granted in current year – value at year-end $ 3,144,766 $ 1,516,142 $ 2,221,730 $ 660,865 $ 4,005,523
Add dividends accrued on unvested shares/share units $ — $ —
Add/subtract change in fair value from end of prior fiscal year to end of current fiscal year for awards made in prior fiscal years that were unvested at end of current fiscal year $ ( 1,345,092 ) $ ( 193,197 ) $ ( 81,272 ) $ ( 6,381,045 ) $ 5,398,965
Add/subtract change in fair value from end of prior fiscal year to vesting date for awards made in prior fiscal years that vested during current fiscal year $ ( 173,945 ) $ ( 72,956 ) $ 138,465 $ ( 2,054,191 ) $ 938,108
Subtract fair value of forfeited awards determined at end of prior year for awards made in prior fiscal years that were forfeited during current fiscal year $ ( 471,263 ) $ ( 492,462 ) $ ( 347,467 ) $ — $ —
Compensation Actually Paid to Non-PEO NEOs $ 2,060,367 $ 1,778,724 $ 2,493,597 $ ( 7,183,678 ) $ 12,019,256

(3) TSR is cumulative (assuming $100 was invested on December 31, 2020) for the measurement periods beginning on December 31,

2020 and ending on December 31 of each of 2025, 2024, 2023, 2022 and 2021, respectively, calculated in accordance with Item

201(e) of Regulation S-K. The peer group for purposes of this table is the S&P 500 Health Care Index. Historic stock price

performance is not necessarily indicative of future stock performance.

81

Pay Versus Performance Disclosure

(4) Reflects “Net Income” in the Company’s Consolidated statements of operations included in its Annual Reports on Form 10-K for

each of the years ended December 31, 2025, 2024, 2023, 2022 and 2021.

TABULAR LIST OF MOST IMPORTANT FINANCIAL PERFORMANCE MEASURES

The unranked list below represents, in Avantor’s view, Avantor’s most important financial measures used to link

compensation to performance:

Company Performance Metrics (1)
Adjusted EPS
Adjusted Operating Income
Free Cash Flow
Relative TSR
Revenue

(1) For more information regarding these company performance metrics and their function in the Company’s executive compensation

program, see “Compensation Discussion and Analysis.” For information about these non-GAAP financial measurements, including

reconciliations to the most directly comparable GAAP-based financial measurements, see “Appendix A — Non-GAAP Financial

Measurements.”

Relationship between Compensation Actually Paid and

Company Performance

COMPENSATION ACTUALLY PAID VS. TOTAL STOCKHOLDER RETURN

As shown in the chart below, the PEO and other NEOs’ CAP amounts are aligned with our TSR. Our higher TSR in 2021

(both on an absolute basis and relative to the S&P 500 Health Care Index) directionally aligned with higher CAP for the

PEO and NEOs, while weaker performance resulted in negative CAP in 2022 and lower CAP in 2023, 2024 and 2025.

PEO CAP (In Millions) Non-PEO NEOs CAP (In Millions) Avantor TSR S&P 500 Healthcare TSR

(a) Total stockholder return in the above chart, in the case of both the Company and our peer group as noted in footnote 3 of the above

Pay versus Performance Table, reflects the cumulative return of $100 as if invested on December 31, 2020 through December 31,

2025, calculated in accordance with Item 201(e) of Regulation S-K.

COMPENSATION ACTUALLY PAID VS. NET INCOME

82 2026 Proxy Statement

Pay Versus Performance Disclosure

Our strong Net Income growth in 2021 directionally aligned with higher CAP in that year, while Growth was slower in 2022,

2023 and in 2025, which aligned with lower compensation actually paid. The net income increase in 2024 is also aligned

with the increase in CAP.

PEO CAP (In Millions) Non-PEO NEOs CAP (In Millions) Net Income (In Millions)

COMPENSATION ACTUALLY PAID VS. COMPANY SELECTED MEASURE

Our strong Revenue growth in 2021 directionally aligned with higher CAP for that year, while growth was slower in 2022,

2023, 2024 and 2025 which aligned with lower compensation actually paid.

PEO CAP (In Millions) Non-PEO NEOs CAP (In Millions) Revenue (In Millions)

83

PROPOSAL NO. 4 Ratification of Appointment of Independent Registered Public Accounting Firm
The Board of Directors recommends a vote “ FOR ” ITEM 4, the ratification of the appointment of Deloitte & Touche LLP as our independent registered public accounting firm.

The Audit and Finance Committee approved the selection of Deloitte & Touche LLP as our independent registered public

accounting firm for 2026. The Board of Directors and the Audit and Finance Committee recommend that stockholders

ratify this selection. Deloitte & Touche LLP has served as our independent registered public accounting firm since 2010 .

Although the Company is not required to seek stockholder approval of the auditor appointment, the Board believes that

doing so is consistent with good corporate governance practices. If the appointment is not ratified, the Audit and Finance

Committee will explore the reasons for stockholder rejection and will reconsider the appointment.

A representative of Deloitte & Touche LLP will attend the Annual Meeting of Stockholders. Such representative will have

an opportunity to make a statement if he or she desires to do so and will be available to respond to appropriate questions.

84 2026 Proxy Statement

Proposal 4 Ratification of Appointment of Independent Registered Public Accounting Firm

Report of the Audit and Finance Committee

Management has the responsibility for the Company’s financial statements and overall financial reporting process,

including the Company’s systems of internal controls. The independent registered public accounting firm has the

responsibility to conduct an independent audit in accordance with generally accepted auditing standards and to issue an

opinion on the accuracy of the Company’s consolidated financial statements and the effectiveness of the Company’s

internal controls. The Audit and Finance Committee’s responsibility is to monitor and oversee these processes.

The Audit and Finance Committee has reviewed and discussed with management the Company’s audited consolidated

financial statements for the year ended December 31, 2025. The Audit and Finance Committee has discussed with the

Company’s independent registered public accounting firm, which is responsible for expressing an opinion on the

conformity of the Company’s audited consolidated financial statements with generally accepted accounting principles, the

matters required to be discussed under the applicable standards of the Public Company Accounting Oversight Board. The

Audit and Finance Committee has received from the independent registered public accounting firm the written disclosures

and the letter required by applicable requirements of the Public Company Accounting Oversight Board regarding the

independent registered public accounting firm’s communications with the Audit and Finance Committee concerning

independence, and has discussed with the independent registered public accounting firm its independence. In considering

the independence of the Company’s independent registered public accounting firm, the Audit and Finance Committee took

into consideration the amount and nature of the fees paid to the firm for non-audit services, as described below.

In reliance on the review and discussions described above, the Audit and Finance Committee has recommended to the

Board of Directors that the audited consolidated financial statements be included in the Company’s Annual Report on

Form 10-K for the year ended December 31, 2025, for filing with the SEC.

Respectfully submitted by the Audit and Finance Committee of the Board of Directors.

Joseph Massaro , Chair

Juan Andres

Simon Dingemans *

Louise Makin

Sanjeev Mehra *

Mala Murthy

  • Messrs. Dingemans and Mehra were appointed to the Audit and Finance Committee on February 19, 2026 and did not participate in

the reviews and discussions described in the Audit Committee Report prior to that date.

85

Proposal 4 Ratification of Appointment of Independent Registered Public Accounting Firm

Audit and Non-Audit Fees

Deloitte & Touche LLP served as our independent registered public accounting firm for the fiscal years ended December

31, 2024, and 2025. Fees and expenses for services rendered by Deloitte & Touche LLP in 2024 and 2025 were approved

by our Audit and Finance Committee. We have determined that the provision of these services is compatible with

maintaining the independence of our independent registered public accounting firm.

The following table presents Deloitte & Touche LLP’s fees and expenses for services rendered to us for the past two fiscal

years (in thousands):

Year Ended December 31, 2025 ($) 2024 ($)
Audit Fees (1) 5,572 5,186
Audit-Related Fees (2) 1,000
Tax Fees (3) 1,075 10
All Other Fees (4) 2 595
Total 6,649 6,791

(1) Audit fees include fees for professional services rendered for the audits of our annual financial statements, international statutory

audits and the reviews of our interim financial statements, which were included in the year to which the audit or review related;

(2) Consist of fees billed for the audit of divested business unit financial statements and separate attestation engagements in connection

with statutory audits.

(3) Consists of fees billed for services rendered in connection with tax compliance, tax advice and tax planning.

(4) For 2025, all other fees consists of fees billed for accounting research tools and related database subscriptions. For 2024, all other

fees primarily consists of fees billed for professional services rendered in connection with due diligence for a contemplated

transaction.

Pre-approval Policy for Auditor Services

The Audit and Finance Committee has the sole and direct responsibility and authority for the appointment, termination and

compensation to be paid to the independent registered public accounting firm. The Audit and Finance Committee has the

responsibility to approve, in advance, all audit services and permissible non-audit services to be performed by the

independent registered public accounting firm, as well as compensation to be paid with respect to such services.

Our Audit and Finance Committee Charter authorizes the Committee to delegate authority to pre-approve audit and

permissible non-audit services to a member of the Committee. Any decisions made by such member under delegated

authority must be presented to the full Audit and Finance Committee at its next scheduled meeting.

86 2026 Proxy Statement

Questions and Answers About the Meeting and Voting

1. Who can attend the Annual Meeting?

Stockholders of record as of March 13, 2026, will be able to attend and participate in the Annual Meeting online, vote

and submit questions during the Annual Meeting by accessing www.virtualshareholdermeeting.com/AVTR2026 . If

your shares are held in a brokerage account or by another nominee or trustee, you are considered the beneficial

owner of shares held in street name. If you are a beneficial owner, you are also invited to attend and participate in the

Annual Meeting online. For more information, see “Questions and Answers About the Meeting and Voting — 1. How do

I attend the 2026 Annual Meeting?” If you do not comply with the procedures outlined above, you will not be admitted

to the virtual Annual Meeting.

Even if you plan to attend the Annual Meeting online, we recommend that you also vote by proxy as described herein

so that your vote will be counted if you decide not to attend the Annual Meeting.

2. How do I attend the 2026 Annual Meeting?

This year’s Annual Meeting will again be a virtual meeting, conducted via live audio webcast on the Internet.

Stockholders of record as of March 13, 2026, will be able to attend and participate in the Annual Meeting online, vote

and submit questions during the Annual Meeting by accessing www.virtualshareholdermeeting.com/AVTR2026 . If

your shares are held in a brokerage account or by another nominee or trustee, you are also invited to attend and

participate in the Annual Meeting online but you need to take additional steps if you wish to vote during the meeting.

For more information, see “How do I vote if I am a beneficial owner of shares?”

Even if you plan to attend the Annual Meeting online, we recommend that you vote by proxy in advance so

that your vote will be counted if your plans change.

Access to the Audio Webcast of the Annual Meeting . The live audio webcast of the Annual Meeting will begin

promptly at 11:00 a.m., Eastern Time. Online access to the audio webcast will open approximately thirty minutes

earlier to allow time for you to log in and test the computer audio system. We encourage you to access the meeting

prior to the start time.

Log in Instructions . To attend the online Annual Meeting, log in at www.virtualshareholdermeeting.com/

AVTR2026 . Stockholders of record will need to enter the 16-digit control number appearing on their Notice of Internet

Availability of Proxy Materials or proxy card. If you are a beneficial stockholder, you may contact the bank, broker or

other institution where you hold your account if you have questions about obtaining your control number. If you do not

have a control number, you may still attend the meeting as a guest in listen-only mode.

Submitting Questions at the Virtual Annual Meeting . As part of the Annual Meeting, we will hold a live question and

answer session to answer properly submitted questions that are pertinent to the Company and meeting matters, as

time permits. Questions and answers will be grouped by topic and substantially similar questions will be grouped and

answered once.

Technical Assistance . Beginning 30 minutes prior to the start of and during the virtual Annual Meeting, we will have a

support team ready to assist stockholders with any technical difficulties they may have accessing or hearing the

virtual meeting.

If you encounter any difficulties accessing the virtual meeting during the check-in or meeting time, please call the

technical support number that will be posted on the virtual shareholder meeting log in page.

3. Am I entitled to vote and how many votes do I have?

If you were a stockholder of record of Avantor common stock at the close of business on March 13, 2026, you are

eligible to vote at the Annual Meeting. You have one vote for each share you own for each director nominee and for

each other matter presented for vote.

87

Questions and Answers About the Meeting and Voting

4. What business will be conducted at the Annual Meeting?

The table below shows, for each proposal, the vote required to approve the proposal and the

Board’s recommendation.

Proposal Required Vote Board Recommendation Effect of Abstentions and Broker Non-Votes
Item 1: Election of nine director nominees to serve one-year terms expiring in 2027 A nominee must receive a majority of the votes cast with respect to that nominee’s election at the meeting at which a quorum is present by the holders of capital stock entitled to vote in the election to be elected, which means that the number of votes cast “for” a nominee’s election must exceed the number of votes cast “against” that nominee’s election. FOR Each Nominee No effect
Item 2: Advisory approval of named executive officer compensation The affirmative vote of a majority of the voting power of the outstanding common stock present in person or represented by proxy and entitled to vote on this proposal is required to approve, on an advisory, non- binding basis, the compensation paid to our named executive officers. FOR Abstentions will be counted as present and entitled to vote on the proposal and will therefore have the effect of a negative vote. Broker non-votes will be counted as present for purposes of determining whether there is a quorum but will have no effect on the outcome of the proposal.
Item 3: Advisory vote on the frequency of future advisory votes on executive compensation The affirmative vote of a majority of the voting power of the outstanding common stock present in person or represented by proxy and entitled to vote on this proposal, however, because the vote is advisory and non-binding, if none of the frequency options receive such majority, the option receiving the greatest number of votes will be considered the expressed preference (on a non-binding, advisory basis) of the stockholders. ONE YEAR No Effect
Item 4: Ratification of appointment of Deloitte & Touche LLP as our independent registered public accounting firm for 2026 The affirmative vote of a majority of the voting power of the outstanding common stock present in person or represented by proxy and entitled to vote on this proposal is required to ratify the appointment of Deloitte & Touche LLP as our independent registered public accounting firm for 2026. FOR Abstentions will be counted as present and entitled to vote on the proposal and will therefore have the effect of a negative vote. We do not expect there to be any broker non-votes with respect to the proposal.

88 2026 Proxy Statement

Questions and Answers About the Meeting and Voting

5. What constitutes a “quorum” for the meeting?

A quorum consists of the holders of record of a majority of the voting power of the issued and outstanding shares

entitled to vote at the meeting, present in person or represented by proxy. At the close of business on March 13, 2026,

Avantor had 676,110,712 shares of common stock (excluding treasury shares) outstanding. A quorum is necessary to

conduct business at the Annual Meeting. You are part of the quorum if you have voted by proxy. Abstentions and

shares represented by “broker non-votes” are counted for purposes of determining the presence of a quorum.

6. What is the difference between holding shares as a stockholder of record/registered stockholder and as a

beneficial owner of shares?

Stockholder of Record or Registered Stockholder . If your shares of common stock are registered directly in your

name with our transfer agent, Equiniti Trust Company, you are considered a “stockholder of record” or a “registered

stockholder” of those shares.

Beneficial Owner of Shares . If your shares are held in an account at a bank, brokerage firm or other similar

organization, including shares purchased through our employee stock purchase plan, then you are a beneficial owner

of shares held in “street name.” In that case, you will have received these proxy materials from the bank, brokerage

firm or other similar organization that holds your shares. As a beneficial owner, you have the right to direct your bank,

brokerage firm or similar organization as to how to vote the shares held in your account.

7. How do I vote if I am a stockholder of record?

By Telephone or Internet . Stockholders of record can vote by touchtone telephone within the United States, U.S.

territories and Canada, using the toll-free telephone number on the proxy card or Notice, or through the Internet, using

the procedures and instructions described on the proxy card or Notice. The telephone and Internet voting procedures

are designed to authenticate stockholders’ identities, to allow stockholders to vote their shares, and to confirm that

their instructions have been recorded properly.

By Written Proxy . If you sign and return your proxy card but do not mark any selections giving specific voting

instructions, your shares represented by that proxy will be voted as recommended by the Board of Directors.

Online During the Meeting . Stockholders of record may vote during the virtual Annual Meeting by visiting the Annual

Meeting website at www.virtualshareholdermeeting.com/AVTR2026 and entering their control number listed on

their proxy card or Notice. For more information, see “How do I attend the 2026 Annual Meeting?”

Even if you plan to attend the Annual Meeting, we recommend that you also vote by proxy so that your vote will be

counted if your plans change.

8. How do I vote if I am a beneficial owner of shares?

Your broker is not permitted to vote on your behalf on the matters to be considered at the Annual Meeting, except on

the ratification of the appointment of Deloitte & Touche LLP as our independent registered public accounting firm,

without your specific instructions. If you are a beneficial owner, we encourage you to complete and return the voting

instruction form you receive from your broker, bank or other financial institution or follow the instructions provided to

you for voting your shares via telephone or the Internet. Your vote will not be counted unless you communicate your

voting decisions to your broker, bank or other financial institution before the date of the Annual Meeting. If you wish to

personally vote your shares at the meeting, you must obtain a legal proxy from your broker, bank or other financial

institution and register in advance of the Annual Meeting. For more information, see “How do I attend the 2026 Annual

Meeting?”

9. What is a broker non-vote?

A “broker non-vote” occurs when a broker submits a proxy for the meeting with respect to a routine proposal but does

not vote on non-routine proposals because the beneficial owner did not provide voting instructions on those matters.

Under NYSE rules, the proposal to ratify the appointment of an independent registered public accounting firm (Item 4)

is considered a “routine” proposal. This means that brokerage firms may vote in their discretion on behalf of clients

(beneficial owners) who have not furnished voting instructions at least 15 days before the date of the Annual Meeting.

In contrast, all of the other proposals set forth in this Proxy Statement are “non-routine”—brokerage firms that have not

received voting instructions from their clients on these matters may not vote on these proposals.

89

Questions and Answers About the Meeting and Voting

10. Can I revoke my proxy or change my vote?

If you are a record holder of shares, you may revoke your proxy at any time before it is actually voted at the Annual

Meeting by taking one of the following actions:

Delivering written notice of revocation to our Secretary at Radnor Corporate Center, Building One, Suite 200, 100

Matsonford Road, Radnor, PA 19087 by 11:59 p.m. EDT on May 6, 2026;

Submitting a later-dated proxy by 11:59 p.m. on May 6, 2026; or

Attending the Annual Meeting online and voting by following the instructions at

www.virtualshareholdermeeting.com/AVTR2026 .

Your attendance at the Annual Meeting online will not, by itself, constitute revocation of your proxy. You may also

choose another person to represent you by attending the Annual Meeting by executing a form of proxy designating

that person to act on your behalf.

If you are a beneficial stockholder and wish to revoke or change your voting instructions, you will need to follow the

procedures established by your brokerage firm, bank or other record owner.

11. Why did I receive a one-page notice in the mail regarding the Internet availability of proxy materials instead of

a full set of proxy materials?

As permitted by the SEC, instead of mailing a printed copy of our proxy materials to each stockholder of record, we

are furnishing proxy materials, including this Proxy Statement and our Annual Report on Form 10-K for the year ended

December 31, 2025, by providing access to such documents on the Internet. Stockholders will not receive printed

copies of the proxy materials unless they request them. Instead, commencing on or about March 27, 2026, a Notice of

Internet Availability of Proxy Materials (the “Notice”) was sent to most of our stockholders. The Notice explains how to

access and review the proxy materials and how to submit your proxy on the Internet. If you would like to receive a

paper or email copy of our proxy materials, please follow the instructions for requesting such materials in the Notice.

12. Why did my household only receive one set of proxy materials or one notice of Internet availability when two

stockholders live here?

SEC rules permit companies and intermediaries such as brokers to satisfy delivery requirements for Proxy Statements

and notices with respect to two or more stockholders sharing the same address by delivering a single Proxy Statement

or a single notice addressed to those stockholders. This process, which is commonly referred to as “householding,”

provides cost savings for companies and helps the environment by conserving natural resources. Some brokers

household proxy materials, delivering a single Proxy Statement or notice to multiple stockholders sharing an address

unless contrary instructions have been received from the affected stockholders. Once you have received notice from

your broker that they will be householding materials to your address, householding will continue until you are notified

otherwise or until you revoke your consent. If, at any time, you no longer wish to participate in householding and would

prefer to receive a separate Proxy Statement or notice, or if your household is receiving multiple copies of these

documents and you wish to request that future deliveries be limited to a single copy, please notify your broker. You can

also request prompt delivery of a copy of this Proxy Statement and the Annual Report by contacting the Corporate

Secretary at 610-386-1700 or: Avantor Inc., Corporate Secretary’s Office, Radnor Corporate Center, Building One,

Suite 200, 100 Matsonford Road, Radnor, PA 19087.

13. Who pays for the solicitation of proxies?

We will pay the cost of soliciting proxies. Proxies may be solicited on our behalf by directors, officers or employees (for

no additional compensation) in person or by telephone, email or fax. Brokers and other nominees will be requested to

solicit proxies or authorizations from beneficial owners and will be reimbursed for their reasonable expenses.

90 2026 Proxy Statement

Questions and Answers About the Meeting and Voting

14. Is my vote confidential?

Yes. Proxy cards, ballots and voting tabulations that identify stockholders are kept confidential, except:

as necessary to meet applicable legal requirements and to assert or defend claims for or against the Company;

in the case of a contested proxy solicitation;

if a stockholder makes a written comment on the proxy card or otherwise communicates their vote to

management; or

to allow the independent inspector of election to certify the results of the vote.

Broadridge Investor Communication Solutions, the independent proxy tabulator used by Avantor, counts the votes and

acts as the judge of election for the meeting.

15. How can I propose actions for consideration at the 2027 annual meeting of stockholders or nominate

individuals to serve as directors?

Stockholder Proposals . To be eligible for inclusion in the Proxy Statement for our 2027 Annual Meeting of

Stockholders pursuant to Rule 14a-8, we must receive your proposal on or before November 27, 2026. The proposal

should be mailed by certified mail return receipt requested to our Corporate Secretary’s Office, Avantor, Inc., 100

Matsonford Road, Building One, Suite 200, Radnor, PA 19087. Failure to deliver a proposal in accordance with this

procedure may result in it not being deemed timely received.

To make a director nomination or present other business for consideration at our 2027 Annual Meeting of Stockholders

that will not be included in the Proxy Statement, you must submit a timely notice in accordance with the procedures

described in our bylaws. To be timely, your notice must be delivered to our Secretary between January 7 , 2027, and

February 6 , 2027. If the date of the Annual Meeting of Stockholders to be held in 2027 is advanced or delayed by more

than 30 days from the anniversary date of this year’s Annual Meeting of Stockholders, your notice must be received no

earlier than 120 days prior to the Annual Meeting of Stockholders to be held in 2027 and not later than the close of

business on the later of the 90th day prior to such annual meeting or the 10th day following the day on which public

announcement of the date of such meeting is first made. Any such proposal will be considered timely only if it is

otherwise in compliance with the requirements set forth in our bylaws.

Further, if you intend to nominate a director and solicit proxies in support of such director nominee(s) (other than the

Company’s nominees) at the 2027 Annual Meeting of Stockholders in reliance on Rule 14a-19 under the Exchange

Act, in addition to the requirements set forth in the Company’s bylaws, you must also comply with the additional

requirements of Rule 14a-19 under the Exchange Act.

Proxy Access Nominations . Pursuant to our proxy access bylaw provision, a stockholder, or a group of up to 20

stockholders, that has continuously owned for three years at least 3% of our outstanding common shares, may

nominate and include in the annual meeting proxy materials up to the greater of two directors or 20% of the number of

directors serving on the Board, if the stockholder(s) and the nominee(s) meet the requirements specified in our bylaws.

Notice of director nominations submitted under the proxy access bylaw provision for the 2027 Annual Meeting of

Stockholders must be received by the Corporate Secretary between October 28 , 2026, and November 27 , 2026.

16. How can I obtain a copy of Avantor’s Annual Report on Form 10-K?

We make available, free of charge on our website, all of our filings that are made electronically with the SEC, including

Forms 10-K, 10-Q and 8-K. To access these filings, please go to our website ( www.avantorsciences.com ). Copies of

our Annual Report on Form 10-K for the year ended December 31, 2025, including financial statements thereto, filed

with the SEC, are also available without charge to stockholders upon written request addressed to:

Investor Relations

Avantor, Inc.

Radnor Corporate Center, Building One, Suite 200

100 Matsonford Road

Radnor, PA 19087

91

Other Business

The Board does not know of any other matters to be brought before the meeting. If other matters are presented, the proxy

holders have discretionary authority to vote all proxies in accordance with their best judgment. Discretionary authority for

them to do so is provided for in the proxy card.

March 27, 2026

CLAUDIUS O. SOKENU

Executive Vice President, Chief Legal and

Compliance Officer and Corporate Secretary

92 2026 Proxy Statement

Appendix A

AVANTOR, INC. AND SUBSIDIARIES

NON-GAAP FINANCIAL MEASUREMENTS

As appropriate, we supplement our results of operations determined in accordance with U.S. generally accepted

accounting principles (“GAAP”) with certain non-GAAP financial measurements that we believe are useful to investors,

creditors and others in assessing our performance. These measures should not be considered in isolation or as a

substitute for reported GAAP results because they may include or exclude certain items as compared to similar GAAP-

based measures, and such measures may not be comparable to similarly-titled measures reported by other companies.

Rather, these measures should be considered as an additional way of viewing aspects of our operations that provide a

more complete understanding of our business. We strongly encourage investors to review our consolidated financial

statements included in reports filed with the SEC in their entirety and not rely solely on any one, single financial

measurement or communication.

We have provided reconciliations of the following non-GAAP measures referred to in this Proxy Statement:

Organic net sales growth (decline) eliminates from our reported net sales change the impacts of revenues from

acquisitions and divestitures that occurred in the last year (as applicable) and changes in foreign currency exchange

rates. We believe that this measurement is useful as a way to measure and evaluate our underlying commercial

operating performance consistently across our segments and the periods presented.

Adjusted operating income is our net income or loss adjusted for the following items: (i) interest expense, (ii) income tax

expense, (iii) amortization of acquired intangible assets, (iv) losses on extinguishment of debt, (v) charges associated

with the impairment of certain assets, (vi) gain on sale of business, and (vii) certain other adjustments. We believe that

this measurement is as ways to analyze the underlying trends in our business consistently across the periods

presented. Additionally, Adjusted operating income is our segment profitability measure under GAAP.

Adjusted EBITDA is our net income or loss adjusted for the following items: (i) interest expense, (ii) income tax

expense, (iii) amortization of acquired intangible assets, (iv) depreciation expense, (v) losses on extinguishment of

debt, (vi) charges associated with the impairment of certain assets, (vii) gain on sale of business, and (viii) certain other

adjustments. We believe that this measurement is useful as a way to analyze the underlying trends in our business

consistently across the periods presented.

Adjusted EPS is our adjusted net income divided by our diluted GAAP weighted average share count adjusted for anti-

dilutive instruments. We believe that this measurement is an additional way to analyze the underlying trends in our

business consistently across the periods presented.

Adjusted net income is our net income or loss first adjusted for the following items: (i) amortization of acquired

intangible assets, (ii) losses on extinguishment of debt, (iii) charges associated with the impairment of certain assets,

(iv) gain on sale of business, and (v) certain other adjustments. From this amount, we then add or subtract an assumed

incremental income tax impact on the above noted pre-tax adjustments, using estimated tax rates, to arrive at Adjusted

Net Income. We believe that this measure is useful as a way to analyze the business consistently across the periods

presented.

Adjusted net leverage is equal to our gross debt, reduced by our cash and cash equivalents, divided by our trailing 12-

month Adjusted EBITDA (excluding stock-based compensation expense and including the expected run-rate effect of

cost synergies and the incremental results of completed acquisitions and divestitures as if those acquisitions and

divestitures had occurred on the first day of the trailing 12-month period). We believe that this measurement is a useful

way to evaluate and measure the Company’s capital allocation strategies and the underlying trends in the business.

Free cash flow is equal to our cash flows from operating activities, less capital expenditures, plus direct transaction

costs and income taxes paid related to acquisitions and divestitures (as applicable) in the period. Free cash flow

conversion is free cash flow divided by adjusted net income. We believe that these measures are useful as it provides a

view on the Company’s ability to generate cash for use in financing or investing activities.

93

Appendix A

Adjusted EBITDA

(in millions) Year ended December 31, — 2025 2024
Net income (loss) $ (530.2) $ 711.5
Amortization 301.1 299.8
Loss on extinguishment of debt 4.6 10.9
Restructuring and severance charges (1) 29.8 82.8
Transformation expenses (2) 61.7 58.9
Reserve for certain legal matters, net (3) 7.3 9.2
Other (4) 20.9 (3.9)
Impairment charges (5) 785.0
Gain (loss) on sale of business (6) 5.1 (446.6)
Pension termination charges (7) 16.3 9.3
Income tax (benefit) expense applicable to pretax adjustments (87.9) (54.2)
Adjusted Net Income 613.7 677.7
Interest expense, net 169.8 218.8
Depreciation 109.1 105.7
Income tax provision applicable to Adjusted Net Income 176.8 196.6
Adjusted EBITDA $ 1,069.4 $ 1,198.8

(1) Reflects the incremental expenses incurred in the period related to restructuring initiatives to increase profitability and productivity.

Costs included in this caption are specific to employee severance, site-related exit costs, and contract termination costs. These

expenses represent costs incurred to achieve the Company’s publicly-announced cost transformation initiative.

(2) Represents incremental expenses directly associated with the Company’s publicly-announced cost transformation initiative, primarily

related to the cost of external advisors.

(3) Represents charges and legal costs, net of recoveries, in connection with certain litigation and other contingencies that are unrelated

to our core operations and not reflective of on-going business and operating results.

(4) Represents net foreign currency (gain) loss from financing activities, other stock-based compensation expense (benefit), $6.7 million

of severance and transition costs associated with the replacement of our Chief Executive Officer in 2025, and other costs.

(5) Relates to the goodwill impairment of our Distribution reporting unit.

(6) The amount reported in 2024 reflects the gain on the sale of our Clinical Services business. The amount reported in 2025 reflects

post-closing purchase price adjustments related to that sale.

(7) Represents pension termination charges related to termination of our U.S. Pension Plan.

94 2026 Proxy Statement

Appendix A

Adjusted Operating Income

(in millions) Year ended December 31, — 2025 2024
Net income (loss) $ (530.2) $ 711.5
Interest expense, net 169.8 218.8
Income tax expense 88.9 142.4
Loss on extinguishment of debt 4.6 10.9
Other (expense) income, net 20.7 1.2
Operating income (loss) (246.2) 1,084.8
Amortization 301.1 299.8
Restructuring and severance charges (1) 29.8 82.8
Transformation expenses (2) 61.7 58.9
Reserve for certain legal matters, net (3) 7.3 9.2
Other (4) 14.0 0.9
Impairment charges (5) 785.0
Gain (loss) on sale of business (6) 5.1 (446.6)
Adjusted Operating Income $ 957.8 $ 1,089.8

(1) Reflects the incremental expenses incurred in the period related to restructuring initiatives to increase profitability and productivity.

Costs included in this caption are specific to employee severance, site-related exit costs, and contract termination costs. These

expenses represent costs incurred to achieve the Company’s publicly-announced cost transformation initiative.

(2) Represents incremental expenses directly associated with the Company’s publicly-announced cost transformation initiative, primarily

related to the cost of external advisors.

(3) Represents charges and legal costs, net of recoveries, in connection with certain litigation and other contingencies that are unrelated

to our core operations and not reflective of on-going business and operating results.

(4) Represents other stock-based compensation expense (benefit), $6.7 million of severance and transition costs associated with the

replacement of our Chief Executive Officer in 2025, and other costs.

(5) Relates to the goodwill impairment of our Distribution reporting unit.

(6) The amount reported in 2024 reflects the gain on the sale of our Clinical Services business. The amount reported in 2025 reflects

post-closing purchase price adjustments related to that sale.

95

Appendix A

Adjusted Earnings per Share

(shares in millions) Year ended December 31, — 2025 2024
Diluted earnings (loss) per share (GAAP) $ (0.78) $ 1.04
Amortization 0.44 0.44
Loss on extinguishment of debt 0.01 0.02
Restructuring and severance charges 0.04 0.12
Transformation expenses 0.09 0.09
Reserve for certain legal matters, net 0.01 0.01
Other 0.04 (0.01)
Impairment charges 1.15
Gain (loss) on sale of business 0.01 (0.65)
Pension termination charges 0.02 0.01
Income tax (benefit) expense applicable to pretax adjustments (0.13) (0.08)
Adjusted EPS (non-GAAP) $ 0.90 $ 0.99
Weighted average shares outstanding:
Share count for Adjusted EPS (non-GAAP) 680.6 681.9

Free Cash Flow

(shares in millions) Year ended December 31, — 2025 2024
Net cash provided by operating activities $ 623.8 $ 840.8
Capital expenditures (128.8) (148.8)
Divestiture-related transaction expenses and taxes paid 1.4 76.3
Free cash flow (non-GAAP) $ 496.4 $ 768.3

96 2026 Proxy Statement

Appendix A

Adjusted Net Leverage

(dollars in millions)
Total debt, gross $ 3,967.9
Less cash and cash equivalents (365.4)
$ 3,602.5
Trailing twelve months Adjusted EBITDA $ 1,069.4
Trailing twelve months ongoing stock-based compensation expense 47.6
$ 1,117.0
Adjusted Net leverage (non-GAAP) 3.2 x

Net Sales

(in millions) December 31, — 2025 2024 Reconciliation of net sales growth (decline) to organic net sales growth (decline) — Net Sales growth (decline) Foreign currency impact Divestiture Impact Organic net sales growth (decline)
Laboratory Solutions $ 4,399.7 $ 4,610.1 $ (210.4) $ 86.0 $ (147.9) $ (148.5)
Bioscience Production 2,152.5 2,173.5 (21.0) 18.7 (39.7)
Total $ 6,552.2 $ 6,783.6 $ (231.4) $ 104.7 $ (147.9) $ (188.2)

CORPORATE

HEADQUARTERS

One Radnor Corporate Center

Building One, Suite 200

100 Matsonford Road

Radnor, PA 19087

(610) 386-1700

AVANTOR, INC. avantor RANDOR CORPORATE CENTER BUILDING ONE, SUITE 200 100 MATSONFORD ROAD RADNOR, PA 19087 TO VOTE, MARK BLOCKS BELOW IN BLUE OR BLACK INK AS FOLLOWS: SCAN TO VIEW MATERIALS & VOTE VOTE BY INTERNET Before The Meeting - Go to www.proxyvote.com or scan the QR Barcode above Use the Internet to transmit your voting instructions and for electronic delivery of information. Vote by 11:59 PM. ET on May 7, 2025. Have your proxy card in hand when you access the web site and follow the instructions to obtain your records and to create an electronic voting instruction form. During The Meeting - Go to www.virtualshareholdermeeting.com/AVTR2025 You may attend the meeting via the Internet and vote during the meeting. Have the information that is printed in the box marked by the arrow available and follow the instructions. VOTE BY PHONE - 1-800-690-6903 Use any touch-tone telephone to transmit your voting instructions. Vote by 11:59 PM. ET on May 7, 2025. Have your proxy card in hand when you call and then follow the instructions. VOTE BY MAIL Mark, sign and date your proxy card and return it in the postage-paid envelope we have provided or return it to Vote Processing, do Broadridge, 51 Mercedes Way, Edgewood, NY 11717. V65534-P26497 THIS

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Important Notice Regarding the Availability of Proxy Materials for the Annual Meeting: The Notice & Proxy Statement and Annual Report are available at www.proxyvote.com V65535-P26497 AVANTOR, INC. Annual Meeting of Stockholders May 8, 2025 11:00 AM ET This proxy is solicited by the Board of Directors The stockholder(s) hereby appoint(s) Claudius Sokenu and Scott Baker, or either of them, as proxies and attorneys-in-fact, each with the power to act without the other and to appoint his substitute, and hereby authorize(s) them to vote, as designated on the reverse side of this proxy card and in their discretion on such other business as may properly come before such meeting, all of the shares of Common Stock of AVANTOR, INC. that the stockholder(s) is/are entitled to vote at the Annual Meeting of Stockholders to be held at 11:00 AM ET on May 8, 2025, and any adjournment or postponement thereof and otherwise to represent the stockholder(s) at such meeting with all powers possessed by the stockholder(s) if personally present at the meeting. This proxy, when properly executed, will be voted in the manner directed herein. If no such direction is made but the card is signed, this proxy will be voted in accordance with the Board of Directors' recommendations, and the discretion of the proxies with respect to such other business as

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