AstraZeneca PLC — Capital/Financing Update 2014

Nov 20, 2014

FINAL TERMS

Final Terms dated 20 November 2014

AstraZeneca PLC Issue of EUR 750,000,000 0.875 per cent. Notes due 24 November 2021 under the U.S.\$5,000,000,000 Euro Medium Term Note Programme

PART A — CONTRACTUAL TERMS

Terms used herein shall be deemed to be defined as such for the purposes of the Conditions (the "Conditions") set forth in the Base Prospectus dated 24 June 2014 and the supplemental Base Prospectus dated 17 November 2014 which together constitute a base prospectus (the "Base Prospectus") for the purposes of Directive 2003/71/EC (the "Prospectus Directive"). This document constitutes the Final Terms of the Notes described herein for the purposes of Article 5.4 of the Prospectus Directive. These Final Terms contain the final terms of the Notes and must be read in conjunction with such Base Prospectus as so supplemented. The expression "Prospectus Directive" means Directive 2003/71/EC (and amendments thereto, including the 2010 PD Amending Directive, to the extent implemented in the relevant Member State) and includes any relevant implementing measures in the Relevant Member State and the expression "2010 PD Amending Directive" means Directive 2010/73/EU).

Full information on the Issuer and the offer of the Notes described herein is only available on the basis of the combination of these Final Terms and the Base Prospectus as so supplemented. The Base Prospectus and the supplemental Base Prospectus are available for viewing at the website of the London Stock Exchange (www.londonstockexchange.com) and copies may be obtained from the specified office of the Principal Paying Agent, being currently located at Winchester House, 1 Great Winchester Street, London EC2N 2DB.

1.	Issuer:		AstraZeneca PLC
2.	(i)	Series Number:	5
	(ii)	Tranche Number:	1
3.		Specified Currency or Currencies:	Euro ("EUR")
4.	Aggregate Nominal Amount:		EUR 750,000,000
5.	Issue Price:		99.119 per cent. of the Aggregate Nominal Amount
6.	(i)	Specified Denominations:	EUR 100,000 and integral multiples of EUR 1,000 in excess thereof up to and including EUR 199,000. Definitive Notes will not be issued in denominations in excess of EUR 199,000.
	(ii)	Calculation Amount:	EUR 1,000
7.	(i)	Issue Date:	24 November 2014

	(ii)	Interest Date:	Commencement		Issue Date
8.	Maturity Date:		24 November 2021
9.	Interest Basis:			0.875 per cent. Fixed Rate
10.	Redemption/Payment Basis:		Redemption at par
11.	Change	of Redemption/Payment Basis:	Interest	or	Not Applicable
12.	Put/Call Options:		Not Applicable
13.	(i)	Status of the Notes:			Senior
	(ii)	Date Board	approval issuance of Notes obtained:	for	29 October 2014

PROVISIONS RELATING TO INTEREST (IF ANY) PAYABLE

14.	Fixed Rate Note Provisions		Applicable
	(i)	Rate of Interest:	0.875 per cent. per annum payable annually in arrear
	(ii)	Interest Payment Date(s):	24 November in each year
	(iii)	Fixed Coupon Amount:	EUR 8.75 per Calculation Amount
	(iv)	Broken Amount(s):	Not Applicable
	(v)	Day Count Fraction:	Actual/Actual (ICMA)
	(vi)	Determination Dates:	Not Applicable
15.	Floating Rate Note Provisions		Not Applicable
16.	Zero Coupon Note Provisions		Not Applicable
		PROVISIONS RELATING TO REDEMPTION
17.	Call Option		Not Applicable
18.	Put Option		Not Applicable
19.	Final Redemption Amount of each Note		EUR 1,000 per Calculation Amount
20.	Early Termination Amount
	Early	Early Redemption Amount (Tax) and Termination Amount per	As set out in the Conditions

Calculation Amount payable on redemption for taxation reasons or, as the case may be, on event of default:

GENERAL PROVISIONS APPLICABLE TO THE NOTES

21.	Form of Notes:	Temporary Global Note exchangeable for a $\frac{1}{1}$ Permanent Global Note which exchangeable for Definitive Notes in the limited circumstances specified in the Permanent Global Note.
22.	New Global Note Form:	Applicable
23.	Additional Financial Centre(s) or London other special provisions relating to Payment Dates
24.	Talons for future Coupons or No Receipts to be attached to Definitive Notes (and dates on which such Talons mature):

Not Applicable 25. Consolidation provisions:

Signed on behalf of the Issuer:

BRe $By:$

Duly authorised

PART B — OTHER INFORMATION

1. LISTING AND ADMISSION TO TRADING

• (i) Admission to trading: Application is expected to be made by the Issuer (or on its behalf) for the Notes to be admitted to trading on the Regulated Market of the London Stock Exchange with effect from 24 November 2014.
• (ii) Estimate of total expenses related to admission to trading: £3650

2. RATINGS

Ratings: The Notes to be issued have been rated:

Standard & Poor's Credit Market Services Europe Limited: AA – (negative)

Moody's Deutschland GmbH: A2 (stable)

3. INTERESTS OF NATURAL AND LEGAL PERSONS INVOLVED IN THE ISSUE/OFFER

Save as discussed in "Subscription and Sale" in the Base Prospectus, so far as the Issuer is aware, no person involved in the offer of the Notes has an interest material to the offer.

4. Fixed Rate Notes Only —YIELD

Indication of yield: 1.006 per cent.

5. OPERATIONAL INFORMATION

ISIN Code: XS1143486865

Common Code: 114348686

New Global Note intended to be held in a manner which would allow Eurosystem eligibility:

Yes. Note that the designation "Yes" simply means that the Notes are intended upon issue to be deposited with Euroclear or Clearstream, Luxembourg as common safekeeper and does not necessarily mean that the Notes will be recognised as eligible collateral for Eurosystem monetary policy and intra-day credit operations by the Eurosystem either upon issue or at any or all times during their life. Such recognition will depend upon satisfaction of the Eurosystem eligibility criteria.

Delivery: Delivery against payment

Names and addresses of additional paying agent(s) (if any): Not Applicable

TEFRA: The D Rules are applicable