ARVINAS, INC. — Director's Dealing 2025

Feb 18, 2025

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: ARVINAS, INC. (ARVN)
CIK: 0001655759
Period of Report: 2025-02-13

Reporting Person: Houston John G (Director, President and CEO)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2025-02-13	Common Stock	A	152000	—	Acquired	1188681	Direct

Derivative Transactions

Date	Security	Exercise Price	Code	Shares	A/D	Expiration	Underlying	Ownership
2025-02-13	Stock Option (right to buy)	$17.67	A	232000	Acquired	2035-02-12	Common Stock (232000)	Direct

Footnotes

F1: The restricted stock units (each, an "RSU") were granted by the issuer on February 13, 2025, pursuant to its 2018 Stock Incentive Plan (the "Plan") and each RSU represents a contingent right to receive one share of the issuer's common stock upon settlement for no consideration. The RSUs will vest over four years: 25% of the RSUs will vest on each of February 13, 2026, February 13, 2027, February 13, 2028 and February 13, 2029, subject to the reporting person's continued service with the Issuer on each vesting date.

F2: The option was granted by the Issuer on February 13, 2025, pursuant to the Plan. The shares underlying the option vest over four years: 1/4 of the shares underlying the award will vest on February 13, 2026, with the remainder of the shares vesting in equal monthly installments following February 13, 2026 through February 13, 2029, subject to the reporting person's continued service with the Issuer on each vesting date.