ARROWHEAD PHARMACEUTICALS, INC. — Director's Dealing 2022

Jan 5, 2022

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: ARROWHEAD PHARMACEUTICALS, INC. (ARWR)
CIK: 0000879407
Period of Report: 2021-12-31

Reporting Person: O'Brien Patrick (General Counsel)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2021-12-31	Common Stock	M	28000	$6.15	Acquired	321375	Direct
2022-01-01	Common Stock	A	60000	$0.00	Acquired	381375	Direct

Derivative Transactions

Date	Security	Exercise Price	Code	Shares	A/D	Expiration	Underlying	Ownership
2021-12-31	Stock Option (right to buy Common Stock)	$6.15	M	28000	Disposed	2026-01-01	Common Stock (28000)	Direct

Footnotes

F1: Represents shares underlying a restricted stock unit, which shares will vest in four equal annual installments.

F2: Includes previously reported shares of common stock underlying Restricted Stock Units granted to the Reporting person which are subject to
certain vesting conditions.

F3: Represents the first vesting date. Option vested over four years from date of grant.