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AROA BIOSURGERY LIMITED — AGM Information 2024
Jul 22, 2024
64426_rns_2024-07-22_0fdfb186-61ac-4d37-aa7e-cd829d0aa872.pdf
AGM Information
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Aroa Biosurgery (ARX) | AGM UNLOCKING REGENERATIVE HEALING FOR EVERY BODY
Important Notice and Disclaimer
This presentation (Presentation) is dated 23 July 2024 and has been prepared by Aroa Biosurgery Ltd, New Zealand company number 1980577, ARBN 638 867 473 (AROA or the Company).
Information in this Presentation
The information in this Presentation is of a general background nature, is in summary form and does not purport to be complete. This Presentation has been prepared in conjunction with an oral presentation and should not be taken out of context. It does not contain all information relevant or necessary for an investment decision or that would be required to be included in a prospectus or other disclosure document under the Corporations Act for an offer of securities in Australia or in any other jurisdiction. This Presentation is intended for investor education purposes only and is not intended as a medical device advertisement. Products shown may not be available in your region. Results may vary. The content of this Presentation is provided as at the date of this Presentation (unless otherwise stated). Except as required by applicable law, AROA does not plan to publicly update or revise any information contained in, or provided with, this Presentation whether as a result of any new information, future events, changed circumstances or otherwise.
Not a prospectus or an offer of securities
This Presentation is not a prospectus or any other offering document under Australian law (or under the law of any other jurisdiction in which an offer of securities may be received. Nothing in this Presentation should be construed as an invitation, offer or recommendation of securities in AROA (or any of its subsidiaries) for subscription, purchase or sale in any jurisdiction. Potential investors should read this presentation in conjunction with AROA’s other periodic and continuous disclosure
announcements lodged with ASX and should rely solely on their own judgement, review and analysis when making an investment decision about AROA.
Future performance
Past performance information in this Presentation is given for illustrative purposes only and should not be relied upon (and is not) an indication of future performance. The Presentation contains certain “forward-looking statements”. The words “forecast”, "outlook", "expect", "anticipate", "estimate", "intend", "believe", "guidance", "should", "could", "may", "will", "predict", "plan" and other similar expressions are intended to identify forward-looking statements. Indications of, and guidance on, future earnings and financial position and performance are also forward-looking statements. These statements are based on current expectations and assumptions regarding AROA’s business and performance, the economy and other circumstances. As with any projection or forecast, forward-looking statements in this Presentation are inherently uncertain and susceptible to changes in circumstances. Opinions involve significant elements of subjective judgement and assumptions as to future events which may or may not be correct. Actual results, performance or achievements may differ materially from those expressed or implied in forward looking statements and statements of opinion. In particular, market data reflects estimates only and investors are cautioned against placing undue reliance on it.
IP notice
AROA, Aroa Biosurgery, AROA ECM, Endoform, Myriad, Myriad Matrix, Morcells, Myriad Morcells, Myriad Ultra, Myriad Flow, Symphony and Enivo are trademarks of Aroa Biosurgery Limited. All other trademarks are properties of their respective owners. ©2024 Aroa Biosurgery Limited
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Clinical Evidence Update
Barnaby May, PhD Chief Scientific Officer, Aroa Biosurgery Limited
CLINICAL EVIDENCE UPDATE
Evidence to Date
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83 peer-reviewed 01 publications >156 conference 02 proceedings 3476 published 03 patients[(1)]
- AROA Biosurgery Limited, data on file
CLINICAL EVIDENCE UPDATE
Highlights from the Evidence
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Authentic Volumetric Resilient and
Complexity Fill Persistent
AROA ECM provides an Provides immediate Persists in the defect
ideal balance of biology & coverage and rapid despite contamination
structure to support tissue granulation tissue to protect and inflammation. [5,6]
regeneration. [1,2] exposed structures. [3,4] Enables cost-
effective utilization. [3,7]
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- Lun, S., et al., Biomaterials, 2010. 31(16): p. 4517-29. 2. Dempsey, S.G., et al., J Proteome Res, 2019. 18(4): p. 1657-1668. 3. Cormican, M.T., et al., ePlasty, 2023. 23: p. e66. 4. Bohn, G.A. and A.E. Chaffin, J Wound Care, 2020. 29(12): p. 742-749. 5.Taarea, R., et al., Trauma Cases Rev 2024. 10(1): p. 102. 6. Hsu, A., et al., Tech Coloproctol, 2023. 27(9): p. 769-774. 7. Bosque, B.A., et al., J Am Podiatr Med Assoc, 2023. 113(3).
VOLUMETRIC FILL
Provides immediate coverage and rapid granulation tissue to protect exposed structures
| REFERENCE | TYPE OF DEFECTS |
DEFECT SIZE | SAMPLE SIZE |
TIME TO TISSUE COVERAGE/FILL (WEEKS) |
|---|---|---|---|---|
| Cormican et al.(1) Traumatic 217.3±77.9 cm2 13 3.3±1.3 w |
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| Taarea et al.(2) Open abdomen 147±62.7 cm2 3 3.5±1.3 w |
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| Bosque et al.(3) Lower extremity 84.2±106 cm2 50 3.7±3.2 w |
- Cormican, M.T., et al., ePlasty, 2023. 23: p. e66. 2. Taarea, R., et al., Trauma Cases Rev 2024. 10(1): p. 102. 3. Bosque, B.A., et al., J Am Podiatr Med Assoc, 2023. 113(3).
RESILIENT AND PERSISTENT
Persists in the defect despite contamination and inflammation
| REFERENCE | TYPE OF DEFECTS |
CDC CONTAMINATION SCORE |
SAMPLE SIZE |
INFECTION RATE |
|---|---|---|---|---|
| Cormican et al.(1) Traumatic Grade II & III 13 0% |
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| Taarea et al.(2) Open abdomen Grade II 3 0% |
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| Bosque et al.(3) Lower extremity Grade IV 50 0% |
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| Chaffin et al.(4) Pilonidal Grade III 6 0% |
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| Chaffin et al.(5) Hidradenitis Grade III 8 0% |
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| Desvigne et al.(6) Non-healing wounds Grade II & III 9 11% |
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| Hsu et al.(7) Anal fistula Grade III 14 0% |
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| Bohn et al.(8) Exposed structures Grade II & III 6 0% |
- Cormican, M.T., et al., ePlasty, 2023. 23: p. e66. 2. Taarea, R., et al., Trauma Cases Rev 2024. 10(1): p. 102. 3. Bosque, B.A., et al., J Am Podiatr Med Assoc, 2023. 113(3). 4. Chaffin, A.E., et al., J Wound Care, 2021. 30(Sup7): p. S28-S34. 5. Chaffin, A.E. and M.C. Buckley, J Wound Care, 2020. 29(11): p. 624-630. 6. Desvigne, M.N., et al., Frontiers in Surgery, 2020. 7(173). 7. Hsu, A., et al., Tech Coloproctol, 2023. 27(9): p. 769-774. 8. Bohn, G.A. and A.E. Chaffin, J Wound Care, 2020. 29(12): p. 742-749.
RESILIENT AND PERSISTENT
Enables cost-effective utilization
| REFERENCE | TYPE OF DEFECTS |
CDC CONTAMINATION SCORE |
SAMPLE SIZE |
MEDIAN NUMBER OF PRODUCT APPLICATIONS |
|---|---|---|---|---|
| Cormican et al.(1) Traumatic Grade II & III 13 1.2 |
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| Taarea et al.(2) Open abdomen Grade II 3 1.0 |
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| Bosque et al.(3) Lower extremity Grade IV 50 1.0 |
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| Chaffin et al.(4) Pilonidal Grade III 6 1.0 |
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| Chaffin et al.(5) Hidradenitis Grade III 8 1.0 |
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| Desvigne et al.(6) Non-healing wounds Grade II & III 9 1.0 |
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| Hsu et al.(7) Anal fistula Grade III 14 1.0 |
||||
| Bohn et al.(8) Exposed structures Grade II & III 6 1.0 |
- Cormican, M.T., et al., ePlasty, 2023. 23: p. e66. 2. Taarea, R., et al., Trauma Cases Rev 2024. 10(1): p. 102. 3. Bosque, B.A., et al., J Am Podiatr Med Assoc, 2023. 113(3). 4. Chaffin, A.E., et al., J Wound Care, 2021. 30(Sup7): p. S28S34. 5. Chaffin, A.E. and M.C. Buckley, J Wound Care, 2020. 29(11): p. 624-630. 6. Desvigne, M.N., et al., Frontiers in Surgery, 2020. 7(173). 7. Hsu, A., et al., Tech Coloproctol, 2023. 27(9): p. 769-774. 8. Bohn, G.A. and A.E. Chaffin, J Wound Care, 2020. 29(12): p. 742-749.
EVIDENCE
Highlights to expect for FY25
Myriad in complex lower extremity reconstruction (prospective)
01
N=130
02 Myriad in trauma reconstruction (prospective) N~40-50 Endoform Real World Evidence – Venous 03 N~2000 Leg Ulcers (retrospective comparative) Symphony diabetic foot ulcers 04 N=120 (prospective comparative)
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CEO and Managing Director’s Report
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SALES
Myriad Sales
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70%
YoY
Growth
16
14
12
10
8
6
4
2
0
FY20 FY21 FY22 FY23 FY24
US$M
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01 Top priority Momentum 02 03 Large volumetric defects 04 Compelling clinical data 05 Disruptive Value MYRIAD US$ 14M TOTAL ADDRESSABLE MARKET US$ 730M
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SALES
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TELA Bio Sales
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40%
YoY
Growth
70
60
50
40
30
20
10
0
FY20 FY21 FY22 FY23 FY24
US$m
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01 Key partnership 02 Hernia & breast portfolio Momentum 03 04 Compelling clinical data 05 Disruptive value OVITEX US$ 63M TOTAL ADDRESSABLE MARKET US$ 1.9B
AROA BIOSURGERY | AGM Why AROA wins...
AROA'S COMPETITIVE ADVANTAGE
Value
01
Improved clinical outcomes
02
Low complication rates
03 Fewer applications
04 Shorter length of stay
05
Reduced product cost
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AROA'S COMPETITIVE ADVANTAGE
Product portfolio
01 AROA ECM scope
02 Unique technical capabilities
03 Complementary Enivo platform
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AROA'S COMPETITIVE ADVANTAGE
Commercial leverage
01
Knowledge & experience
02
Agile & adaptable
03
Energy & drive
04
GPOs / IDNs
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AROA'S COMPETITIVE ADVANTAGE
Low cost of goods
01 High margin manufacturing 02 Continuous improvement 03 Scalable modular process
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Winning =
+ value + product portfolio + commercial leverage + low cost of goods
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AROA GROWTH
Financial outlook[1]
01 Myriad & OviTex drive growth
02 Gross margin improves
03 Sales operating leverage
R&D ~10% sales 04
05 EBITDA margin expands
FY24
Product Revenue NZ$ 69 MILLION (YoY growth 19 – 24%)
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Product
Gross Margin
85%
Normalised
EBITDA
NZ$
($3)
MILLION
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FY25 GUIDANCE
Product Revenue NZ$ 80-87 MILLION ~25% CAGR Product Gross Margin >85% Normalised EBITDA NZ$ 2-6 MILLION
FY25 guidance is presented on a constant currency basis using a NZ$/US$ exchange rate of 0.64, compared to the average exchange rate of 0.61 in FY24. Constant currency removes the impact of exchange rate movements. Guidance is subject to TELA Bio delivering on its CY24 revenue guidance of US$74.5-76.5 million.
AROA BIOSURGERY | AGM Questions & Answers
Thank you for attending
JAMES AGNEW [email protected]
VISIT
www.aroa.com
www.linkedin.com/company /aroa-biosurgery-limited/
64 Richard Pearse Drive, Auckland 2022, New Zealand
PO Box 107111, Auckland Airport, Auckland 2150, New Zealand