Appili Therapeutics Inc. — AGM Information 2021

Jun 30, 2021

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June 30, 2021

1500 Robert-Bourassa Blvd., 7th Floor Montreal QC, H3A 3S8 www.computershare.com

To: All Canadian Securities Regulatory Authorities

Dear Sir/Madam:

We advise of the following with respect to the upcoming Meeting of Security Holders for the subject Issuer:

Meeting Type : Record Date for Notice of Meeting : Record Date for Voting (if applicable) : Beneficial Ownership Determination Date : Meeting Date : Meeting Location (if available) : Issuer sending proxy related materials directly to NOBO: Issuer paying for delivery to OBO:

Annual General Meeting July 09, 2021 July 09, 2021 July 09, 2021 August 19, 2021 Halifax NS No Yes

Notice and Access (NAA) Requirements:

NAA for Beneficial Holders Yes Beneficial Holders Stratification Criteria: Not Applicable NAA for Registered Holders Yes

Voting Security Details:

Description

CLASS A COMMON SHARES

CUSIP Number ISIN 03783R107 CA03783R1073

Sincerely,

Computershare

Agent for APPILI THERAPEUTICS INC.