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Anteris Technologies Global Corp. — AGM Information 2007
Nov 12, 2007
33869_rns_2007-11-12_b5baa8db-58ad-4a24-a225-2ad1663dd7a3.pdf
AGM Information
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Annual General Meeting 2007
bioMD Limited Innovative Biomedical Devices and Technologies
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Annual General Meeting 2007
AGENDA
WELCOME
Mr Robert Scott, Chairman of the Board
CHAIRMAN’S ADDRESS
RESOLUTIONS
1) Adopt the Remuneration Report for the Year Ended 30 June 2007 2) Re-election of Director, Mr Robert Scott
Annual General Meeting 2007
Company Highlights
3 Pre-clinical Trials successfully completed;
Ethics Approval received for a Phase II Human Clinical Trial of cardiovascular patches treated with the ADAPT Tissue Processing Technology;
Presentation at “The Society for Heart Valve Disease” 4[th ] Biennial Meeting in New York by Celxcel’s Chief Scientific Officer, Dr Leon Neethling.
Annual General Meeting 2007
ADAPT[®]
Pre-Clinical Studies 2006/07
ADAPT Treated Bovine Pericardial Tissue Patches in the Jugular Position
ADAPT Treated Kangaroo and Bovine Pericardial Tissue Patches and Kangaroo Carotid Artery Grafts Comparison of ADAPT Treated Bovine Pericardial Patch with two commercially available biomaterial patches.
Annual General Meeting 2007
PHASE II HUMAN CLINICAL TRIAL
CARDIOCEL Bioimplant Tissue Patch (ADAPT treated bovine pericardium)
Trial to be conducted at Universitas Hospital, Bloemfontein, South Africa
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Ethics Committee approval granted - University of the Free State, Bloemfontein
Annual General Meeting 2007
PHASE II HUMAN CLINICAL TRIAL
CARDIOCEL – a bioimplant tissue using ADAPT Tissue Processing Technology for the repair of heart defects in openheart surgery, e.g. “hole in the heart” procedures 50 patient trial CARDIOCEL bioimplants will be implanted over a 12 month period Post-operative 12 month follow up for each patient
Annual General Meeting 2007
PATCH MANUFACTURING
Agreement signed with The Ray & Bill Dobney Cell Tissue Therapies WA manufacturing unit at Royal Perth Hospital
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Annual General Meeting 2007
PATCH MANUFACTURING
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PHASE II HUMAN CLINICAL TRIAL
BIOCOMPATIBILITY TESTING Manufacture of patches for independent testing, giving FDA approved certificate
Annual General Meeting 2007
THE WAY FORWARD
We are here
Animal Trials
Human Trials
Manufacturing facility
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TGA / CE/ FDA
Approval
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Commercialisation Sign Licence / Co-development
Annual General Meeting 2007
Presentation at SHVD
“Enhanced Durability and Biocompatibility of Decellularised Bovine Pericardium, Crosslinked with an Ultra Low Concentration Monomeric Aldehyde and treated with ADAPT®”
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Presentation at “The Society for Heart Valve Disease” 4th Biennial Meeting in New York; Presented by Celxcel’s Chief Scientific Officer,
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Annual General Meeting 2007
ADAPT[®]
Emerging Technologies
Minimally invasive (keyhole) heart valve replacements Patent Foramen Ovale’s (PFO) Heart Defects Using Matrix to deliver “growth factors” and “stem cells”
Annual General Meeting 2007
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ADAPT[®]
ADAPT Tissue Processing Technology can be used to process bioimplants that can be used in 5 surgical specialties
Annual General Meeting 2007
ADAPT[®]
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USA Soft Tissue Market, by type, (US$865M) 2007
Ventral Hernia Staple Line
Repair
Vaginal Sling
Rotator Cuff
Reinforcement
Inguinal Hernia
Repair
Dural Repair Pelvic Floor
Source: Millennium Research Group
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Annual General Meeting 2007
Global Medical Device Companies
Multi-specialty 1[st ] Tier
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Johnson & Johnson
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Boston Scientific
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Bard / Davol
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Covidien
2[nd ] Tier
Annual General Meeting 2007
CSIRO Collaborative Research Agreement
Research completed in the Materials Robustness Phase (Stage II Phase 2) Research commenced in the revised statement of work for Stage III
Provisional patent application lodged in
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Annual General Meeting 2007
Intellectual Property
CSIRO Catheter Material
1 Patent application in progress
ADAPT Tissue Processing Technology 1 Patent granted
16 Patents pending
5 Patent applications
Annual General Meeting 2007
The Year Ahead
Global Partnering for the ADAPT Tissue Processing Technology
Co-product development Co-marketing Licensing
TGA Certification for ADAPT[® ] Tissue Processing Technology
Annual General Meeting 2007
Quality Assurance
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bioMD has Quality Assurance Accreditation to AS9001:2000
Our QA System also meets the requirements of AS13485 which specifically covers the manufacture of Medical Devices.
Annual General Meeting 2007
bioMD at a glance…
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Listed on Australian Stock Exchange - 24 March 2004 Market Capitalisation @ 31/10/07 Fully Paid Ordinary Shares Top 50 Shareholders Group Cash position @ 31/10/07 ADAPT[®] Advanced Tissue Group Average Cash Burn Anti-calcification
$10.12 million 84.3 million 73.6%
$1.9 million $70,000 per month