ANAPTYSBIO, INC — Director's Dealing 2018

May 16, 2018

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: ANAPTYSBIO INC (ANAB)
CIK: 0001370053
Period of Report: 2018-05-11

Reporting Person: Topper James N (Director)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2018-05-11	Common Stock	J	1372000	—	Disposed	973612	Indirect
2018-05-11	Common Stock	J	301024	—	Acquired	301024	Indirect
2018-05-11	Common Stock	J	301024	—	Disposed	0	Indirect
2018-05-11	Common Stock	J	31854	—	Acquired	31854	Direct

Footnotes

F1: Effective May 11, 2018, Frazier Healthcare V, L.P. ("FH V"), distributed in-kind, without consideration, a total of 1,372,000 shares of Common Stock of the Issuer to its general and limited partners. The remaining securities are held by FH V. FHM V, L.L.C. is the general partner of FHM V, L.P. which is the general partner of FH V. The reporting person disclaims beneficial ownership of all shares held by the foregoing entities except to the extent of his pecuniary interest therein, and the inclusion of these shares in this report shall not be deemed an admission of beneficial ownership of all of the reported shares for purposes of Section 16 or for any other purpose.

F2: Shares acquired by FHM V, L.P. through a distribution in-kind from FH V. FHM V, L.L.C. is the general partner of FHM V, L.P. The reporting person disclaims beneficial ownership of all shares held by the foregoing entities except to the extent of his pecuniary interest therein, and the inclusion of these shares in this report shall not be deemed an admission of beneficial ownership of all of the reported shares for purposes of Section 16 or for any other purpose.

F3: Effective May 11, 2018, FHM V, L.P. distributed in-kind, without consideration, a total of 301,024 shares of Common Stock of the Issuer to its limited partners.

F4: Shares acquired by Dr. Topper through a distribution in-kind from FHM V, L.P.