ANAPTYSBIO, INC — Director's Dealing 2017

Jan 31, 2017

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: ANAPTYSBIO INC (ANAB)
CIK: 0001370053
Period of Report: 2017-01-31

Reporting Person: Topper James N (Director, 10% Owner)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2017-01-31	Common Stock	C	2228377	$0.00	Acquired	2228377	Indirect
2017-01-31	Common Stock	C	733740	$0.00	Acquired	733740	Indirect
2017-01-31	Common Stock	C	209095	$0.00	Acquired	209095	Indirect
2017-01-31	Common Stock	P	311291	$15.00	Acquired	1045031	Indirect
2017-01-31	Common Stock	P	88709	$15.00	Acquired	297804	Indirect

Derivative Transactions

Date	Security	Exercise Price	Code	Shares	A/D	Expiration	Underlying	Ownership
2017-01-31	Series B Preferred Stock	$0.00	C	1428571	Disposed		Common Stock (1428571)	Indirect
2017-01-31	Series C Preferred Stock	$0.00	C	604055	Disposed		Common Stock (604055)	Indirect
2017-01-31	Series C-1 Preferred Stock	$0.00	C	195751	Disposed		Common Stock (195751)	Indirect
2017-01-31	Series D Preferred Stock	$0.00	C	733740	Disposed		Common Stock (733740)	Indirect
2017-01-31	Series D Preferred Stock	$0.00	C	209095	Disposed		Common Stock (209095)	Indirect

Footnotes

F1: In connection with the consummation of the Issuer's initial public offering on January 31, 2017, each share of Series B Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into one (1) share of Common Stock for no additional consideration, and had no expiration date. All shares of Common Stock issued upon conversion were aggregated.

F2: Represents shares held by Frazier Healthcare V, L.P., an affiliate of Frazier Healthcare Ventures. Dr. Topper is a General Partner of Frazier Healthcare. Mr. Topper disclaims beneficial ownership of these shares except to the extent of his pecuniary interest therein.

F3: Represents shares held by Frazier Healthcare VII, L.P., an affiliate of Frazier Healthcare Ventures. Dr. Topper is a General Partner of Frazier Healthcare. Mr. Topper disclaims beneficial ownership of these shares except to the extent of his pecuniary interest therein.

F4: Represents shares held by Frazier Healthcare VII-A, L.P., an affiliate of Frazier Healthcare Ventures. Dr. Topper is a General Partner of Frazier Healthcare. Mr. Topper disclaims beneficial ownership of these shares except to the extent of his pecuniary interest therein.