Amoéba

Share Issue/Capital Change • Sep 15, 2022

PRESS RELEASE

AMOEBA announces the issuance of the sixth tranche of 60 bonds convertible into shares as part of its new bond financing with incentive program with Nice & Green S.A.

Chassieu (France), September 15, 2022– 5.45 pm - AMOEBA (FR0011051598 - ALMIB), producer of a biological biocide capable of eliminating bacterial risk in water and human wounds, and a biocontrol product for plant protection, still in a development phase, announces the issuance of the sixth tranche of bonds convertible into shares ("OCAs") of its new bond financing with incentive program, namely 60 OCAs numbered from 301 to 360 fully issued to Nice & Green S.A.

This issue is part of the agreement entered into with Nice & Green S.A. on December 16, 2020 with a view to setting up a bond financing with a profit-sharing program through the issuance of 480 OCAs with a nominal value of EUR 50,000 each, representing a total nominal amount of the bond issue of EUR 24,000,000 (the "Issuance Agreement").¹

The Chairman and Chief Executive Officer of the Company, using the sub-delegation granted to him by the Board of Directors at its meeting on June 24, 2021, decided to issue on September 15, 2022, 60 OCAs numbered from 301 to 360 to the benefit of Nice & Green S.A. corresponding to the sixth tranche of the bond financing.

As provided for in the issuance agreement, these OCAs were fully subscribed at a price equal to 96% of their nominal value, representing a sixth tranche of OCAs for a total net amount of EUR 2,880,000.

As a reminder, the Company maintains on its website a monitoring table of the OCAs and the number of Amoéba shares in circulation (see Investors section / Regulatories information / Other information).

As an indication, the theoretical impact of the issue of this sixth tranche of OCAs is presented in the tables below in accordance with the OCA conversion formulas on the basis of 92% of the lowest volume-weighted average trading price of the Amoéba share at closing (as published by Bloomberg) over the six (6) trading days immediately preceding September 15, 2022, namely 0.9295 euros.

• Impact of the issue on the share of shareholders' equity per share (calculation based on Amoéba's shareholders' equity as at december 31, 2021, prepared in accordance with International Financial Reporting Standards (IFRS) adjusted for capital increases completed up to September 15, 2022 i. e. 11,445,684 euros and the number of shares comprising the Company's share capital as at September 15, 2022, i. e. 42,472,936 shares) :

¹ See press release of December 21, 2020

	Quote-part des capitaux propres au 31 décembre 2021 (en euros) *
	Base non diluée	Base diluée**
Avant émission de la tranche 6	11 445 684	11 597 412
Après émission de 3 508 197 actions nouvelles résultant de la conversion de 60 OCA	14 325 684	14 477 412

(*) amount of shareholders' equity at 31 december 2021 prepared in accordance with IFRS international financial standards and adjusted for capital increases completed until September 15, 2022 (**) assuming:

• the full exercise of the business creator share subscription warrants and share subscription warrants issued and allocated by Amoéba, exercisable or not, giving the right to subscribe for 200,000 new shares

• the definitive allocation of the conditional rights to receive 25,000 free shares fully subject to a condition of uninterrupted presence.

• Impact of the issue on the participation of a shareholder holding 1% of Amoéba's share capital prior to the issue of the sixth tranche (calculation based on the number of shares comprising Amoéba's share capital as at September 15, 2022, i.e. 42,472,936 shares) :

	Participation de l'actionnaire (en %)
	Base non diluée	Base diluée*
Avant émission de la tranche 6	1%	0,99%
Après émission de 3 508 197 actions nouvelles résultant de la conversion de 60 OCA	0,92%	0,92%

(*) assuming:

• the full exercise of the business creator share subscription warrants and share subscription warrants issued and allocated by Amoéba, exercisable or not, giving the right to subscribe for 200,000 new shares
• the definitive allocation of the conditional rights to receive 25,000 free shares fully subject to a condition of uninterrupted presence.

"The objectives of the financing programme with Nice & Green SA were to develop our biocontrol application worldwide on field crops, to continue the examination of our regulatory dossiers and to restructure the company's debt while strengthening its equity (see press release of 21 December 2020). To date, even before the end of the programme, I am pleased to note that these objectives have been achieved with, in particular, the implementation of 194 field trials between 2021 and 2022, the positive recommendation from Austria for the approval of our biocontrol active substance and the full early repayment of our loan from the EIB. Amoéba can now look forward to a new phase in its development and financing with the construction of a dedicated biocontrol plant and the search for

new opportunities based on the use of the amoeba Willaertia Magna C2c Maky," said Fabrice Plasson, Chairman and CEO of Amoéba.

About AMOEBA:

Founded in 2010, Amoéba is a French company, based in Chassieu (Lyon, France), specialised in the treatment of microbiological risk in natural resources. Over the last ten years, Amoéba has developed a triple scientific, industrial and commercial expertise around the amoeba Willaertia magna C2c Maky. This biological solution is an alternative to the chemical products widely used today. Amoéba is currently focusing on the biocontrol market for plant protection, estimated at €1.6 billion (1), as well as on the US market for industrial water treatment in closed circuits. In the long term, the Company plans to develop new applications such as the treatment of chronic wounds, valued at €751 million (2) in the United States. The commercialisation of crop protection, biocides and healthcare products is subject to local regulatory approvals. The company is currently testing the biocontrol application for plant protection and does not market any products.

Amoéba is listed on Euronext Growth. The Company is a member of the BPI Excellence network and is eligible for the PEA-PME scheme. More information on www.amoeba-nature.com.

1. marketsandmarkets.com, "Wound Care Market by Product, Wound Type, End User - Global Forecast to 2021," 2016.

2.Amoéba data

Contacts:

Amoéba Valérie FILIATRE Directeur Général Adjoint +33 4 26 69 16 00 v.filiatre@amoeba-nature.com

Calyptus Relations investisseurs & Presse Nicolas Hélin/ Mathieu CALLEUX +33 1 53 65 68 68/+33 1 53 65 37 91 amoeba@calyptus.net

Disclaimer

This press release contains certain forward-looking statements concerning AMOEBA which are based on its own assumptions and hypothesis and on information that are available to us. However, AMOEBA gives no assurance that the estimates contained in such forward-looking statements will be verified, which estimates are subject to numerous risks including the risks set forth in the Universal Registration Document of AMOEBA filed with the French Financial Markets Authority (Autorité des Marchés Financiers) on April 12, 2022 under number D22-0280 (a copy of which is available on www.amoeba-nature.com). The forward-looking statements contained in this press release are also subject to risks not yet known to AMOEBA or not currently considered material by AMOEBA. The occurrence of all or part of such risks could cause actual results, financial conditions, performance or achievements of AMOEBA to be materially different from such forward-looking statements.