AMICUS THERAPEUTICS, INC. — Earnings Release 2012

May 10, 2012

*UNITED STATES SECURITIES AND EXCHANGE COMMISSION*

*Washington, D.C. 20549*

*FORM 8-K*

*CURRENT REPORT*

*PURSUANT TO SECTION 13 OR 15(d) OF THE*

*SECURITIES EXCHANGE ACT OF 1934*

Date of Report (Date of earliest event reported): May 10, 2012

*AMICUS THERAPEUTICS, INC.*

(Exact name of registrant as specified in its charter)

Delaware	001-33497	71-0869350
(State or other jurisdiction of incorporation)	(Commission File Number)	(IRS Employer Identification No.)

*1 Cedar Brook Drive, Cranbury, NJ 08512*

(Address of principal executive offices, including zip code)

Registrant’s telephone number, including area code: (609) 662-2000

(Former name or former address, if changed since last report)

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions ( see General Instruction A.2. below):

o Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

o Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

o Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

o Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

SEQ.=1,FOLIO='',FILE='C:\JMS\106199\12-11920-1\task5346367\11920-1-ba.htm',USER='106199',CD='May 10 21:09 2012'

*Item 2.02. Results of Operations and Financial Condition.*

On May 10, 2012, Amicus Therapeutics, Inc. issued a press release announcing its financial results for the quarter ended March 31, 2012. A copy of this press release is attached hereto as Exhibit 99.1.

In accordance with General Instruction B.2. of Form 8-K, the information in this Current Report on Form 8-K, including Exhibit 99.1, shall not be deemed “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), or otherwise subject to the liability of that section, nor shall it be deemed incorporated by reference in any filing under the Securities Act of 1933, as amended, or the Exchange Act, except as expressly set forth by specific reference in such a filing.

*Item 9.01. Financial Statements and Exhibits.*

(d) Exhibits: The Exhibit Index annexed hereto is incorporated herein by reference.

2

SEQ.=1,FOLIO='2',FILE='C:\JMS\106199\12-11920-1\task5346367\11920-1-ba.htm',USER='106199',CD='May 10 21:09 2012'

*SIGNATURES*

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

/s/ Geoffrey P. Gilmore
Geoffrey P. Gilmore
Senior Vice President and General
Counsel

3

SEQ.=1,FOLIO='3',FILE='C:\JMS\106199\12-11920-1\task5346367\11920-1-ba.htm',USER='106199',CD='May 10 21:09 2012'

*EXHIBIT INDEX*

Exhibit No.	Description
99.1	Press Release dated May 10, 2012

4

SEQ.=1,FOLIO='4',FILE='C:\JMS\106199\12-11920-1\task5346367\11920-1-ba.htm',USER='106199',CD='May 10 21:09 2012'